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Green Techniques For Organic Synthesis And Medicinal Chemistry
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Book Synopsis Green Techniques for Organic Synthesis and Medicinal Chemistry by : Wei Zhang
Download or read book Green Techniques for Organic Synthesis and Medicinal Chemistry written by Wei Zhang and published by John Wiley & Sons. This book was released on 2018-03-19 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.
Book Synopsis Green Approaches in Medicinal Chemistry for Sustainable Drug Design by : Bimal K. Banik
Download or read book Green Approaches in Medicinal Chemistry for Sustainable Drug Design written by Bimal K. Banik and published by Elsevier. This book was released on 2020-04-09 with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6. Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability Reflects on techniques for a broad range of compounds and materials Highlights sustainable and green chemistry pathways for molecular synthesis
Book Synopsis Green Sustainable Process for Chemical and Environmental Engineering and Science by : Inamuddin
Download or read book Green Sustainable Process for Chemical and Environmental Engineering and Science written by Inamuddin and published by Elsevier. This book was released on 2021-11-17 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green Sustainable Process for Chemical and Environmental Engineering and Science: Switchable Solvents explores the preparation, properties, chemical processes and applications of this class of green solvents. The book provides an in-depth overview on the area of switchable solvents in various industrial applications, focusing on the purification and extraction of chemical compounds utilizing green chemistry protocols that include liquid-liquid, solid-liquid, liquid-gas and lipids separation technologies. In addition, it includes recent advances in greener extraction and separation processes. This book will be an invaluable guide to students, professors, scientists and R&D industrial specialists working in the field of sustainable chemistry, organic, analytical, chemical engineering, environmental and pharmaceutical sciences. Provides a broad overview of switchable solvents in sustainable chemical processes Compares the use of switchable solvents as greener solvents over conventional solvents Outlines eco-friendly organic synthesis and chemical processes using switchable solvents Lists various industrial separations/extraction processes using switchable solvents
Book Synopsis Organic Synthesis by : Belakatte Parameshwarappa Nandeshwarappa
Download or read book Organic Synthesis written by Belakatte Parameshwarappa Nandeshwarappa and published by BoD – Books on Demand. This book was released on 2020-05-27 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book ‘Organic Synthesis - A Nascent Relook’ is a compendium of the recent progress in all aspects of organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic, green chemistry and medicinal chemistry, polymer chemistry, as well as analytical methods in organic chemistry. The book presents the latest developments in these fields. The chapters are written by chosen experts who are internationally known for their eminent research contributions. Organic synthesis is the complete chemical synthesis of a target molecule. In this book, special emphasis is given to the synthesis of various bioactive heterocycles. Careful selection of various topics in this book will serve the rightful purpose for the chemistry community and the industrial houses at all levels.
Book Synopsis Contemporary Chemical Approaches for Green and Sustainable Drugs by : Marianna Torok
Download or read book Contemporary Chemical Approaches for Green and Sustainable Drugs written by Marianna Torok and published by Elsevier. This book was released on 2022-08-26 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs. This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science. Provides an integrative overview of the environmental risks of drugs and drug by products to support chemists in pre-emptively addressing these issues Highlights the advantages of computer-aided drug design, green and sustainable sourcing, and novel methods for the production of safer, more effective drugs Presents individual chapters written by renowned experts with diverse backgrounds Reflects research in practice through selected case studies and extensive state-of-the-art reference sections to serve as a starting point in the design of any specialized environmentally-conscious medicinal chemistry project
Book Synopsis Green Synthetic Approaches for Biologically Relevant Heterocycles by : Goutam Brahmachari
Download or read book Green Synthetic Approaches for Biologically Relevant Heterocycles written by Goutam Brahmachari and published by Elsevier. This book was released on 2021-03-20 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesis Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches Presents information in an accessible style with an emphasis on sustainability
Book Synopsis Green Chemistry in the Pharmaceutical Industry by : Peter J. Dunn
Download or read book Green Chemistry in the Pharmaceutical Industry written by Peter J. Dunn and published by John Wiley & Sons. This book was released on 2010-02-02 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by three of the world's leading pharmaceutical scientists, this is the first book on this important and hot topic, containing much previously unpublished information. As such, it covers all aspects of green chemistry in the pharmaceutical industry, from simple molecules to complex proteins, and from drug discovery to the fate of pharmaceuticals in the environment. Furthermore, this ready reference contains several convincing case studies from industry, such as Taxol, Pregabalin and Crestor, illustrating how this multidisciplinary approach has yielded efficient and environmentally-friendly processes. Finally, a section on technology and tools highlights the advantages of green chemistry.
Book Synopsis Green Chemistry Strategies for Drug Discovery by : Emily A. Peterson
Download or read book Green Chemistry Strategies for Drug Discovery written by Emily A. Peterson and published by Royal Society of Chemistry. This book was released on 2015-06-30 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incorporation of Green Chemistry is a relatively new phenomenon in the drug discovery discipline, since the scale that chemists operate on in drug discovery is smaller than those of process and manufacturing chemistry. The necessary metrics are more difficult to obtain in drug discovery due to the diversity of reactions conducted. However, pharmaceutical companies are realizing that incorporation of green chemistry techniques at earlier stages of drug development can speed the development of a drug candidate. Edited by experts who have pioneered green chemistry efforts within their own institutions, this book provides a practical guide for both academic and industrial labs wanting to know where to start with introducing greener approaches for greatest return on investment. The Editors have taken a comprehensive approach to the topic covering the entire drug discovery process from molecule conception, through synthesis, formulation and toxicology with specific examples and case studies where green chemistry strategies have been implemented. Currently employed as well as emerging techniques for performing greener drug discovery chemistry are addressed as well as cutting-edge topics like biologics discovery. Moreover, important surrounding issues such as intellectual property are included. This book will serve as a practical guide for both academic and industrial chemists who work across the breadth of the drug discovery discipline. Ultimately, readers will learn how to incorporate green chemistry strategies into their everyday workflow without slowing down their science.
Book Synopsis Green Chemistry: Synthesis of Bioactive Heterocycles by : K. L. Ameta
Download or read book Green Chemistry: Synthesis of Bioactive Heterocycles written by K. L. Ameta and published by Springer. This book was released on 2014-06-17 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc. The book also provides an insight of how green chemistry techniques are specific to the bioactive heterocyclic compounds.
Book Synopsis Process Chemistry in the Pharmaceutical Industry by : Kumar Gadamasetti
Download or read book Process Chemistry in the Pharmaceutical Industry written by Kumar Gadamasetti and published by CRC Press. This book was released on 1999-05-06 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing guidance for chemists and other scientists entering pharmaceutical discovery and development, this up-to-the-minute reference presents contributions from an international group of nearly 50 renowned researchers—offering a solid grounding in synthetic and physical organic chemistry, and clarifying the roles of various specialties in the development of new drugs. Featuring over 1000 references, tables, and illustrations, Process Chemistry in the Pharmaceutical Industry is sure to find its way to the bookshelves of organic, physical, analytical, process, and medicinal chemists and biochemists; pharmacists; and upper-level undergraduate and graduate students in these disciplines.
Book Synopsis Green and Sustainable Medicinal Chemistry by : Louise Summerton
Download or read book Green and Sustainable Medicinal Chemistry written by Louise Summerton and published by Royal Society of Chemistry. This book was released on 2016-03-08 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical manufacturing was one of the first industries to recognize the importance of green chemistry, with pioneering work including green chemistry metrics and alternative solvents and reagents. Today, other topical factors also have to be taken into consideration, such as rapidly depleting resources, high energy costs and new legislation. This book addresses current challenges in modern green chemical technologies and sustainability thinking. It encompasses a broad range of topics covered by the CHEM21 project – Europe’s largest public-private partnership project which aims to develop a toolbox of sustainable technologies for green chemical intermediate manufacture. Divided into two sections, the book first gives an overview of the key green chemistry tools, guidance and considerations aimed at developing greener processes, before moving on to look at cutting-edge synthetic methodologies. Featuring innovative research, this book is an invaluable reference for chemists across academia and industry wanting to further their knowledge and understanding of this important topic.
Book Synopsis Green Chemistry in Drug Discovery by : Paul F. Richardson
Download or read book Green Chemistry in Drug Discovery written by Paul F. Richardson and published by Humana. This book was released on 2021-10-26 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book highlights several emerging areas in the implementation of green chemistry in medicinal chemistry drug discovery with a specific focus on their application to the expeditious discovery of new biologically active entities. Divided into three sections, the collection explores greener approaches to chemical transformations that are both prevalent and have been highlighted as challenging within the pharmaceutical industry, overall synthetic strategy, as well as the implementation and impact of a range of enabling technologies within medicinal chemistry. As a volume of the Methods in Pharmacology and Toxicology series, chapters provide the kind of key insight that can guide researchers toward greater success in the lab. Authoritative and practical, Green Chemistry in Drug Discovery: From Academia to Industry provides both a fundamental insight into the progress that has been made as well as some of the challenges that still exist for these techniques to be effectively implemented in the drug discovery process in a routine manner.
Book Synopsis Protecting-Group-Free Organic Synthesis by : Rodney A. Fernandes
Download or read book Protecting-Group-Free Organic Synthesis written by Rodney A. Fernandes and published by John Wiley & Sons. This book was released on 2018-05-25 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a comprehensive account of established protecting-group-free synthetic routes to molecules of medium to high complexity This book supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and back the global need of practicing green chemistry. The only resource of its kind to focus entirely on protecting-group-free synthesis, it is edited by a leading practitioner in the field, and features enlightening contributions by top experts and researchers from across the globe. The introductory chapter includes a concise review of historical developments, and discusses the concepts, need for, and future prospects of protecting-group-free synthesis. Following this, the book presents information on protecting-group-free synthesis of complex natural products and analogues, heterocycles, drugs, and related pharmaceuticals. Later chapters discuss practicing protecting-group-free synthesis using carbohydrates and of glycosyl derivatives, glycol-polymers and glyco-conjugates. The book concludes with a chapter on latent functionality as a tactic toward formal protecting-group-free synthesis. A comprehensive account of established protecting-group-free (PGF) synthetic routes to molecules of medium to high complexity Benefits total synthesis, methodology development and drug synthesis researchers Supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and support the global need of practicing green chemistry Covers a topic that is gaining importance because it renders syntheses more economical Protecting-Group-Free Organic Synthesis: Improving Economy and Efficiency is an important book for academic researchers in synthetic organic chemistry, green chemistry, medicinal and pharmaceutical chemistry, biochemistry, and drug discovery.
Book Synopsis Green Organic Reactions by : Gopinathan Anilkumar
Download or read book Green Organic Reactions written by Gopinathan Anilkumar and published by Springer Nature. This book was released on 2021-03-27 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents important developments and applications of green chemistry, especially in the field of organic chemistry. The chapters give a brief account of green organic reactions in water, green organic reactions using microwave and in solvent-free conditions. In depth discussions on the green aspects of ionic liquids, flow reactions, and recoverable catalysts are provided in this book. An exclusive chapter devoted to green Lewis acid is also included. The potential of supercritical fluids as green solvents in various areas of organic reactions is explained as well. This book will be a valuable reference for beginners as well as advanced researchers interested in green organic chemistry.
Book Synopsis Greene's Protective Groups in Organic Synthesis by : Peter G. M. Wuts
Download or read book Greene's Protective Groups in Organic Synthesis written by Peter G. M. Wuts and published by John Wiley & Sons. This book was released on 2012-12-20 with total page 1108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fourth Edition of Greene's Protective Groups in Organic Synthesis continues to be an indispensable reference for controlling the reactivity of the most common functional groups during a synthetic sequence. This new edition incorporates the significant developments in the field since publication of the third edition in 1998, including... New protective groups such as the fluorous family and the uniquely removable 2-methoxybenzenesulfonyl group for the protection of amines New techniques for the formation and cleavage of existing protective groups, with examples to illustrate each new technique Expanded coverage of the unexpected side reactions that occur with protective groups New chart covering the selective deprotection of silyl ethers 3,100 new references from the professional literature The content is organized around the functional group to be protected, and ranges from the simplest to the most complex and highly specialized protective groups.
Book Synopsis Greener Synthesis of Organic Compounds by : Ahindra Nag
Download or read book Greener Synthesis of Organic Compounds written by Ahindra Nag and published by CRC Press. This book was released on 2022-05-30 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an interdisciplinary, integrative overview of environmental problem-solving using mild reaction conditions, green reagents, waste free and energy efficient synthesis in both industry and academic world. Discussions include a broad, integrated perspective on sustainability, integrated risk, multi-scale changes and impacts taking place within ecosystems worldwide. Features: This book serves as a reference book for scientific investigators who need to do greener synthesis of organic compounds, drugs and natural products under mild reaction condition using green reagents, eco-friendly catalysts and benign reaction mediums over traditional synthetic processes which is a key driving force of scientists. Greener synthesis of multiple value-added heterocycles opens up a new horizon towards the organic catalysis and for this purpose, development of natural resources acts as an effective catalyst. Using environmentally friendly reaction medium e.g. ACC, WETSA, WEBSA have been used for the synthesis of some crucial heterocyclic scaffolds such as bisenols and 2-amino-4H-pyrans, tetraketones, pyrans, and biaryls. This book can also be used as a textbook for graduate and post graduate level courses for students. Furthermore, the problems with answers in book will add better understanding for students.
Book Synopsis Organic Sonochemistry by : Jean-Marc Lévêque
Download or read book Organic Sonochemistry written by Jean-Marc Lévêque and published by Springer. This book was released on 2018-10-11 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides informative, useful, and stimulating reading on the topic of organic sonochemistry – the core of ultrasound-based applications. Given the increasing interest in new and improved technologies, allied to their green and sustainable character (not always a valid premise), there is a great attraction for organic chemists to apply these protocols in synthesis and process chemistry. Unfortunately, as with other enabling technologies, many researchers new to the field have received a simple and dishonest message: just switch on! Therefore a significant portion of sonochemical syntheses lack reproducibility (surprisingly cavitation control and/or ultrasonic parameters are omitted) and the actual role of sonication remains uncertain. While this book does not provide a detailed description of fundamentals, the introductory remarks highlight the importance of cavitational effects and their experimental control. It presents a number of concepts of sonochemical reactivity and empirical rules with pertinent examples, often from classical and recent literature. It then focuses on scenarios of current interest where organic chemistry, and synthesis in particular, may benefit from sonication in terms of both chemical and mechanical activation. The “sustainable corner” of this field is largely exemplified through concepts like atom economy, renewable sources, wasteless syntheses, and benign solvents as reaction media. This book is useful for both researchers and graduate students, especially those familiar with the field of sonochemistry and applications of ultrasound in general. However, it is also of interest to a broader audience as it discusses the fundamentals, techniques, and experimental skills necessary for scientists wishing to initiate the use of ultrasound in their domain of expertise.
