A Primer in Biological Data Analysis and Visualization Using R

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Publisher : Columbia University Press
ISBN 13 : 0231554400
Total Pages : 255 pages
Book Rating : 4.2/5 (315 download)

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Book Synopsis A Primer in Biological Data Analysis and Visualization Using R by : Gregg Hartvigsen

Download or read book A Primer in Biological Data Analysis and Visualization Using R written by Gregg Hartvigsen and published by Columbia University Press. This book was released on 2021-06-29 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: R is the most widely used open-source statistical and programming environment for the analysis and visualization of biological data. Drawing on Gregg Hartvigsen’s extensive experience teaching biostatistics and modeling biological systems, this text is an engaging, practical, and lab-oriented introduction to R for students in the life sciences. Underscoring the importance of R and RStudio in organizing, computing, and visualizing biological statistics and data, Hartvigsen guides readers through the processes of correctly entering and analyzing data and using R to visualize data using histograms, boxplots, barplots, scatterplots, and other common graph types. He covers testing data for normality, defining and identifying outliers, and working with non-normally distributed data. Students are introduced to common one- and two-sample tests as well as one- and two-way analysis of variance (ANOVA), correlation, and linear and nonlinear regression analyses. This volume also includes a section on advanced procedures and a chapter outlining algorithms and the art of programming using R. This second edition has been revised to be current with the versions of R software released since the book’s original publication. It features updated terminology, sources, and examples throughout.

Primer to Analysis of Genomic Data Using R

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Author :
Publisher : Springer
ISBN 13 : 3319144758
Total Pages : 270 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Primer to Analysis of Genomic Data Using R by : Cedric Gondro

Download or read book Primer to Analysis of Genomic Data Using R written by Cedric Gondro and published by Springer. This book was released on 2015-05-18 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through this book, researchers and students will learn to use R for analysis of large-scale genomic data and how to create routines to automate analytical steps. The philosophy behind the book is to start with real world raw datasets and perform all the analytical steps needed to reach final results. Though theory plays an important role, this is a practical book for graduate and undergraduate courses in bioinformatics and genomic analysis or for use in lab sessions. How to handle and manage high-throughput genomic data, create automated workflows and speed up analyses in R is also taught. A wide range of R packages useful for working with genomic data are illustrated with practical examples. The key topics covered are association studies, genomic prediction, estimation of population genetic parameters and diversity, gene expression analysis, functional annotation of results using publically available databases and how to work efficiently in R with large genomic datasets. Important principles are demonstrated and illustrated through engaging examples which invite the reader to work with the provided datasets. Some methods that are discussed in this volume include: signatures of selection, population parameters (LD, FST, FIS, etc); use of a genomic relationship matrix for population diversity studies; use of SNP data for parentage testing; snpBLUP and gBLUP for genomic prediction. Step-by-step, all the R code required for a genome-wide association study is shown: starting from raw SNP data, how to build databases to handle and manage the data, quality control and filtering measures, association testing and evaluation of results, through to identification and functional annotation of candidate genes. Similarly, gene expression analyses are shown using microarray and RNAseq data. At a time when genomic data is decidedly big, the skills from this book are critical. In recent years R has become the de facto tool for analysis of gene expression data, in addition to its prominent role in analysis of genomic data. Benefits to using R include the integrated development environment for analysis, flexibility and control of the analytic workflow. Included topics are core components of advanced undergraduate and graduate classes in bioinformatics, genomics and statistical genetics. This book is also designed to be used by students in computer science and statistics who want to learn the practical aspects of genomic analysis without delving into algorithmic details. The datasets used throughout the book may be downloaded from the publisher’s website.

Molecular Data Analysis Using R

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Publisher : John Wiley & Sons
ISBN 13 : 1119165024
Total Pages : 354 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Molecular Data Analysis Using R by : Csaba Ortutay

Download or read book Molecular Data Analysis Using R written by Csaba Ortutay and published by John Wiley & Sons. This book was released on 2017-02-06 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the difficulties experienced by wet lab researchers with the statistical analysis of molecular biology related data. The authors explain how to use R and Bioconductor for the analysis of experimental data in the field of molecular biology. The content is based upon two university courses for bioinformatics and experimental biology students (Biological Data Analysis with R and High-throughput Data Analysis with R). The material is divided into chapters based upon the experimental methods used in the laboratories. Key features include: • Broad appeal--the authors target their material to researchers in several levels, ensuring that the basics are always covered. • First book to explain how to use R and Bioconductor for the analysis of several types of experimental data in the field of molecular biology. • Focuses on R and Bioconductor, which are widely used for data analysis. One great benefit of R and Bioconductor is that there is a vast user community and very active discussion in place, in addition to the practice of sharing codes. Further, R is the platform for implementing new analysis approaches, therefore novel methods are available early for R users.

A Primer for Computational Biology

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Publisher :
ISBN 13 : 9780870719264
Total Pages : 0 pages
Book Rating : 4.7/5 (192 download)

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Book Synopsis A Primer for Computational Biology by : Shawn T. O'Neil

Download or read book A Primer for Computational Biology written by Shawn T. O'Neil and published by . This book was released on 2017-12-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Primer for Computational Biology aims to provide life scientists and students the skills necessary for research in a data-rich world. The text covers accessing and using remote servers via the command-line, writing programs and pipelines for data analysis, and provides useful vocabulary for interdisciplinary work. The book is broken into three parts: Introduction to Unix/Linux: The command-line is the "natural environment" of scientific computing, and this part covers a wide range of topics, including logging in, working with files and directories, installing programs and writing scripts, and the powerful "pipe" operator for file and data manipulation. Programming in Python: Python is both a premier language for learning and a common choice in scientific software development. This part covers the basic concepts in programming (data types, if-statements and loops, functions) via examples of DNA-sequence analysis. This part also covers more complex subjects in software development such as objects and classes, modules, and APIs. Programming in R: The R language specializes in statistical data analysis, and is also quite useful for visualizing large datasets. This third part covers the basics of R as a programming language (data types, if-statements, functions, loops and when to use them) as well as techniques for large-scale, multi-test analyses. Other topics include S3 classes and data visualization with ggplot2.

Data Analysis for the Life Sciences with R

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Publisher : CRC Press
ISBN 13 : 1498775861
Total Pages : 461 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Data Analysis for the Life Sciences with R by : Rafael A. Irizarry

Download or read book Data Analysis for the Life Sciences with R written by Rafael A. Irizarry and published by CRC Press. This book was released on 2016-10-04 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.

An Introduction to R

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Publisher : Pelagic Publishing Ltd
ISBN 13 : 1784273392
Total Pages : 311 pages
Book Rating : 4.7/5 (842 download)

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Book Synopsis An Introduction to R by : Mark Gardener

Download or read book An Introduction to R written by Mark Gardener and published by Pelagic Publishing Ltd. This book was released on 2023-05-23 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: The modern world is awash with data. The R Project is a statistical environment and programming language that can help to make sense of it all. A huge open-source project, R has become enormously popular because of its power and flexibility. With R you can organise, analyse and visualise data. This clear and methodical book will help you learn how to use R from the ground up, giving you a start in the world of data science. Learning about data is important in many academic and business settings, and R offers a potent and adaptable programming toolbox. The book covers a range of topics, including: importing/exporting data, summarising data, visualising data, managing and manipulating data objects, data analysis (regression, ANOVA and association among others) and programming functions. Regardless of your background or specialty, you'll find this book the perfect primer on data analysis, data visualisation and data management, and a springboard for further exploration.

Biostatistics with R

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Publisher : Springer Science & Business Media
ISBN 13 : 1461413028
Total Pages : 355 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Biostatistics with R by : Babak Shahbaba

Download or read book Biostatistics with R written by Babak Shahbaba and published by Springer Science & Business Media. This book was released on 2011-12-15 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biostatistics with R is designed around the dynamic interplay among statistical methods, their applications in biology, and their implementation. The book explains basic statistical concepts with a simple yet rigorous language. The development of ideas is in the context of real applied problems, for which step-by-step instructions for using R and R-Commander are provided. Topics include data exploration, estimation, hypothesis testing, linear regression analysis, and clustering with two appendices on installing and using R and R-Commander. A novel feature of this book is an introduction to Bayesian analysis. This author discusses basic statistical analysis through a series of biological examples using R and R-Commander as computational tools. The book is ideal for instructors of basic statistics for biologists and other health scientists. The step-by-step application of statistical methods discussed in this book allows readers, who are interested in statistics and its application in biology, to use the book as a self-learning text.

Computational Genomics with R

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Publisher : CRC Press
ISBN 13 : 1498781861
Total Pages : 462 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Computational Genomics with R by : Altuna Akalin

Download or read book Computational Genomics with R written by Altuna Akalin and published by CRC Press. This book was released on 2020-12-16 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.

Using R for Biostatistics

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Publisher : Springer Nature
ISBN 13 : 3030624048
Total Pages : 929 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Using R for Biostatistics by : Thomas W. MacFarland

Download or read book Using R for Biostatistics written by Thomas W. MacFarland and published by Springer Nature. This book was released on 2021-03-02 with total page 929 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the open source R software language that can be implemented in biostatistics for data organization, statistical analysis, and graphical presentation. In the years since the authors’ 2014 work Introduction to Data Analysis and Graphical Presentation in Biostatistics with R, the R user community has grown exponentially and the R language has increased in maturity and functionality. This updated volume expands upon skill-sets useful for students and practitioners in the biological sciences by describing how to work with data in an efficient manner, how to engage in meaningful statistical analyses from multiple perspectives, and how to generate high-quality graphics for professional publication of their research. A common theme for research in the diverse biological sciences is that decision-making depends on the empirical use of data. Beginning with a focus on data from a parametric perspective, the authors address topics such as Student t-Tests for independent samples and matched pairs; oneway and twoway analyses of variance; and correlation and linear regression. The authors also demonstrate the importance of a nonparametric perspective for quality assurance through chapters on the Mann-Whitney U Test, Wilcoxon Matched-Pairs Signed-Ranks test, Kruskal-Wallis H-Test for Oneway Analysis of Variance, and the Friedman Twoway Analysis of Variance. To address the element of data presentation, the book also provides an extensive review of the many graphical functions available with R. There are now perhaps more than 15,000 external packages available to the R community. The authors place special emphasis on graphics using the lattice package and the ggplot2 package, as well as less common, but equally useful, figures such as bean plots, strip charts, and violin plots. A robust package of supplementary material, as well as an introduction of the development of both R and the discipline of biostatistics, makes this ideal for novice learners as well as more experienced practitioners.

R Bioinformatics Cookbook

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Publisher :
ISBN 13 : 9781789950694
Total Pages : 316 pages
Book Rating : 4.9/5 (56 download)

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Book Synopsis R Bioinformatics Cookbook by : Dan MacLean

Download or read book R Bioinformatics Cookbook written by Dan MacLean and published by . This book was released on 2019-10-11 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 60 recipes to model and handle real-life biological data using modern libraries from the R ecosystem Key Features Apply modern R packages to handle biological data using real-world examples Represent biological data with advanced visualizations suitable for research and publications Handle real-world problems in bioinformatics such as next-generation sequencing, metagenomics, and automating analyses Book Description Handling biological data effectively requires an in-depth knowledge of machine learning techniques and computational skills, along with an understanding of how to use tools such as edgeR and DESeq. With the R Bioinformatics Cookbook, you'll explore all this and more, tackling common and not-so-common challenges in the bioinformatics domain using real-world examples. This book will use a recipe-based approach to show you how to perform practical research and analysis in computational biology with R. You will learn how to effectively analyze your data with the latest tools in Bioconductor, ggplot, and tidyverse. The book will guide you through the essential tools in Bioconductor to help you understand and carry out protocols in RNAseq, phylogenetics, genomics, and sequence analysis. As you progress, you will get up to speed with how machine learning techniques can be used in the bioinformatics domain. You will gradually develop key computational skills such as creating reusable workflows in R Markdown and packages for code reuse. By the end of this book, you'll have gained a solid understanding of the most important and widely used techniques in bioinformatic analysis and the tools you need to work with real biological data. What you will learn Employ Bioconductor to determine differential expressions in RNAseq data Run SAMtools and develop pipelines to find single nucleotide polymorphisms (SNPs) and Indels Use ggplot to create and annotate a range of visualizations Query external databases with Ensembl to find functional genomics information Execute large-scale multiple sequence alignment with DECIPHER to perform comparative genomics Use d3.js and Plotly to create dynamic and interactive web graphics Use k-nearest neighbors, support vector machines and random forests to find groups and classify data Who this book is for This book is for bioinformaticians, data analysts, researchers, and R developers who want to address intermediate-to-advanced biological and bioinformatics problems by learning through a recipe-based approach. Working knowledge of R programming language and basic knowledge of bioinformatics are prerequisites.

Data Analysis Using R (Low Priced Edition): A Primer for Data Scientist

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Author :
Publisher : Notion Press
ISBN 13 : 9781685549596
Total Pages : 500 pages
Book Rating : 4.5/5 (495 download)

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Book Synopsis Data Analysis Using R (Low Priced Edition): A Primer for Data Scientist by : DR DHAVAL MAHETA.

Download or read book Data Analysis Using R (Low Priced Edition): A Primer for Data Scientist written by DR DHAVAL MAHETA. and published by Notion Press. This book was released on 2021-11-22 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this book is to address the needs of students in using software for data science. The pace and content of this book is set in such a way so that it gives user friendly approach to students and other learners. The key features of this book are more than 60 packages have been discussed with relevant examples. The author has also incorporated the data analysis using R-Commander which is Graphic User Interface (GUI) of R programming. This book is a primer for upcoming fields such as Data Science and Machine Learning.

Data Analysis in Medicine and Health using R

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Publisher : CRC Press
ISBN 13 : 1000957322
Total Pages : 329 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Data Analysis in Medicine and Health using R by : Kamarul Imran Musa

Download or read book Data Analysis in Medicine and Health using R written by Kamarul Imran Musa and published by CRC Press. This book was released on 2023-09-12 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data analysis plays a vital role in guiding medical treatment plans, patient care, and the formulation of control and prevention policies in the field of healthcare. In today's era, researchers in these domains require a firm grasp of data, statistical concepts, and programming skills due to the increasing complexity of data. Reproducible analyses and cutting-edge statistical methods are becoming increasingly necessary. This book, which is both comprehensive and highly practical, addresses these challenges by laying a solid foundation of data and statistical theory for readers. Subsequently, it equips them with practical skills to conduct analyses using the powerful R programming language, widely used by statisticians. The book takes a gentle approach to help readers navigate data and statistical analysis using R, minimizing the learning curve. RStudio is used as the integrated development environment (IDE) for enhanced productivity for readers to run their R codes. Following a logical sequence commonly applied in medical and health research, the book covers fundamental concepts of data analysis and statistical modeling techniques. It provides readers, including those with limited statistical knowledge and programming skills, with hands-on experience through R programming. The online version of this book is available on bookdown.org, a publishing platform provided by RStudio, PBC specifically designed to host books written using the "bookdown" package in R. Additionally, all R codes and datasets in this book can be found on the author's GitHub repository.

Genomics Data Analysis for Crop Improvement

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Publisher : Springer Nature
ISBN 13 : 9819969131
Total Pages : 378 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Genomics Data Analysis for Crop Improvement by : Priyanka Anjoy

Download or read book Genomics Data Analysis for Crop Improvement written by Priyanka Anjoy and published by Springer Nature. This book was released on 2024-02-10 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses complex problems associated with crop improvement programs, using a wide range of programming solutions, for genomics data handling and sustainable agriculture. It describes important concepts in genomics data analysis and sequence-based mapping approaches along with references. The book contains 16 chapters on recent developments in several methods of genomic data analysis for crop improvements and sustainable agriculture, all authored by eminent researchers who are experts in their fields. These chapters focus on applications of a wide range of key bioinformatics topics, including assembly, annotation, and visualization of next-generation sequencing (NGS) data; expression profiles of coding and noncoding RNA; statistical and quantitative genetics; trait-based association analysis, quantitative trait loci (QTL) mapping, and artificial intelligence in genomic studies. Real examples and case studies in the book will come in handy when applying the techniques. The relative scarcity of reference materials covering bioinformatics applications as compared with the readily available books also enhances the utility of this book. The targeted readers of the book are scientists, researchers, and bioinformaticians from genomics and advanced breeding in different areas. The book will appeal to the applied researchers engaged in crop improvements and sustainable agriculture by using bioinformatics tools, students, research project leaders, and practitioners from the various marginal disciplines and interdisciplinary research.

Biostatistical Design and Analysis Using R

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Publisher : John Wiley & Sons
ISBN 13 : 144436247X
Total Pages : 578 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Biostatistical Design and Analysis Using R by : Dr Murray Logan

Download or read book Biostatistical Design and Analysis Using R written by Dr Murray Logan and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: R — the statistical and graphical environment is rapidly emerging as an important set of teaching and research tools for biologists. This book draws upon the popularity and free availability of R to couple the theory and practice of biostatistics into a single treatment, so as to provide a textbook for biologists learning statistics, R, or both. An abridged description of biostatistical principles and analysis sequence keys are combined together with worked examples of the practical use of R into a complete practical guide to designing and analyzing real biological research. Topics covered include: simple hypothesis testing, graphing exploratory data analysis and graphical summaries regression (linear, multi and non-linear) simple and complex ANOVA and ANCOVA designs (including nested, factorial, blocking, spit-plot and repeated measures) frequency analysis and generalized linear models. Linear mixed effects modeling is also incorporated extensively throughout as an alternative to traditional modeling techniques. The book is accompanied by a companion website www.wiley.com/go/logan/r with an extensive set of resources comprising all R scripts and data sets used in the book, additional worked examples, the biology package, and other instructional materials and links.

Introduction to Data Science

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Publisher : CRC Press
ISBN 13 : 1000708039
Total Pages : 794 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Introduction to Data Science by : Rafael A. Irizarry

Download or read book Introduction to Data Science written by Rafael A. Irizarry and published by CRC Press. This book was released on 2019-11-20 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Data Science: Data Analysis and Prediction Algorithms with R introduces concepts and skills that can help you tackle real-world data analysis challenges. It covers concepts from probability, statistical inference, linear regression, and machine learning. It also helps you develop skills such as R programming, data wrangling, data visualization, predictive algorithm building, file organization with UNIX/Linux shell, version control with Git and GitHub, and reproducible document preparation. This book is a textbook for a first course in data science. No previous knowledge of R is necessary, although some experience with programming may be helpful. The book is divided into six parts: R, data visualization, statistics with R, data wrangling, machine learning, and productivity tools. Each part has several chapters meant to be presented as one lecture. The author uses motivating case studies that realistically mimic a data scientist’s experience. He starts by asking specific questions and answers these through data analysis so concepts are learned as a means to answering the questions. Examples of the case studies included are: US murder rates by state, self-reported student heights, trends in world health and economics, the impact of vaccines on infectious disease rates, the financial crisis of 2007-2008, election forecasting, building a baseball team, image processing of hand-written digits, and movie recommendation systems. The statistical concepts used to answer the case study questions are only briefly introduced, so complementing with a probability and statistics textbook is highly recommended for in-depth understanding of these concepts. If you read and understand the chapters and complete the exercises, you will be prepared to learn the more advanced concepts and skills needed to become an expert.

Presenting Scientific Data in R

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Author :
Publisher : Oxford University Press
ISBN 13 : 0198870477
Total Pages : 205 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis Presenting Scientific Data in R by : ROSALIND K.. RUXTON HUMPHREYS (GRAEME D.)

Download or read book Presenting Scientific Data in R written by ROSALIND K.. RUXTON HUMPHREYS (GRAEME D.) and published by Oxford University Press. This book was released on 2022-07-15 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written primarily for students embarking on an undergraduate bioscience degree, this primer provides an accessible, straightforward, and approachable guide to data presentation using R.

Graphical Data Analysis with R

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Publisher : CRC Press
ISBN 13 : 1498715249
Total Pages : 306 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Graphical Data Analysis with R by : Antony Unwin

Download or read book Graphical Data Analysis with R written by Antony Unwin and published by CRC Press. This book was released on 2015-03-25 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: See How Graphics Reveal Information Graphical Data Analysis with R shows you what information you can gain from graphical displays. The book focuses on why you draw graphics to display data and which graphics to draw (and uses R to do so). All the datasets are available in R or one of its packages and the R code is available at rosuda.org/GDA. Graphical data analysis is useful for data cleaning, exploring data structure, detecting outliers and unusual groups, identifying trends and clusters, spotting local patterns, evaluating modelling output, and presenting results. This book guides you in choosing graphics and understanding what information you can glean from them. It can be used as a primary text in a graphical data analysis course or as a supplement in a statistics course. Colour graphics are used throughout.