Vaccines For Dummies

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119787831
Total Pages : 46 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Vaccines For Dummies by : Megan Coffee

Download or read book Vaccines For Dummies written by Megan Coffee and published by John Wiley & Sons. This book was released on 2021-07-09 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inoculate yourself against the confusion and misinformation surrounding vaccines Measles, mumps, and rubella—oh my! Why are we vaccinating our children—and ourselves—against these diseases, and what goes on in our bodies after the needle comes out? Vaccines For Dummies will inform and entertain you about all things vax, including how the first vaccines were discovered, what’s in modern vaccines, how they are tested and approved for use, and why the CDC’s vaccine schedule is what it is. Inside, you’ll also find a complete guide to vaccine benefits, potential side effects, and contraindications, so you’ll be ready when shot time comes. From the very first inoculations hundreds of years ago to the brand new COVID-19 shot, creating immunity to diseases has become a human specialty. If you’re wondering how safe and how necessary it all is, you aren’t alone. In Vaccines For Dummies, we’ll explore the issue from every angle, empowering you to take charge of your wellbeing. With this book, you will: Discover the ABCs of vaccines, including what they’re made of and how they work Learn about each recommended childhood and adult immunization, plus the seasonal flu shot, all with this evidence-based guide Take a journey through vaccine history, meeting the major players of yesterday and today Decide what’s right for your family, with the help of the most recent vaccine science Parents, parents-to-be, adults of any age, and anyone who wants to delve into the microscopic world of pathogens and their arch nemeses (antigens and antibodies) will get a double dose of knowledge from Vaccines For Dummies.

How to Make a Vaccine

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Author :
Publisher : University of Chicago Press
ISBN 13 : 022679265X
Total Pages : 185 pages
Book Rating : 4.2/5 (267 download)

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Book Synopsis How to Make a Vaccine by : John Rhodes

Download or read book How to Make a Vaccine written by John Rhodes and published by University of Chicago Press. This book was released on 2021-04-12 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Distinguished expert in vaccine development John Rhodes tells the story of the first approved COVID-19 vaccines and offers an essential, up-to-the-minute primer on how scientists discover, test, and distribute vaccines. As the COVID-19 pandemic has affected every corner of the world, changing our relationship to our communities, to our jobs, and to each other, the most pressing question has been—when will it end? Researchers around the globe are urgently trying to answer this question by racing to test and distribute a vaccine that could end the greatest public health threat of our time. In How to Make a Vaccine, an expert who has firsthand experience developing vaccines tells an optimistic story of how three hundred years of vaccine discovery and a century and a half of immunology research have come together at this powerful moment—and will lead to multiple COVID-19 vaccines. Dr. John Rhodes draws on his experience as an immunologist, including working alongside a young Anthony Fauci, to unravel the mystery of how vaccines are designed, tested, and produced at scale for global deployment. Concise and accessible, this book describes in everyday language how the immune system evolved to combat infection, how viruses responded by evolving ways to evade our defenses, and how vaccines do their work. That history, and the pace of current research developments, make Rhodes hopeful that multiple vaccines will protect us. Today the complex workings of the immune system are well understood. The tools needed by biomedical scientists stand ready to be used, and more than 160 vaccine candidates have already been produced. But defeating COVID-19 won’t be the end of the story: Rhodes describes how discoveries today are also empowering scientists to combat future threats to global health, including a recent breakthrough in the development of genetic vaccines, which have never before been used in humans. As the world prepares for a vaccine, Rhodes offers a current and informative look at the science and strategies that deliver solutions to the crisis.

Vaccine Development and Manufacturing

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118870905
Total Pages : 456 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Vaccine Development and Manufacturing by : Emily P. Wen

Download or read book Vaccine Development and Manufacturing written by Emily P. Wen and published by John Wiley & Sons. This book was released on 2014-10-06 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccine Manufacturing and Production is an invaluable reference on how to produce a vaccine - from beginning to end - addressing all classes of vaccines from a processing, production, and regulatory viewpoint. It will provide comprehensive information on the various fields involved in the production of vaccines, from fermentation, purification, formulation, to regulatory filing and facility designs. In recent years, there have been tremendous advances in all aspects of vaccine manufacturing. Improved technology and growth media have been developed for the production of cell culture with high cell density or fermentation. Vaccine Manufacturing and Production will serve as a reference on all aspects of vaccine production by providing an in-depth description of the available technologies for making different types of vaccines and the current thinking in facility designs and supply issues. This book will provide insight to the issues scientists face when producing a vaccine, the steps that are involved, and will serve as a reference tool regarding state-of-the-art vaccine manufacturing technologies and facility set-up. Highlights include: Comprehensive coverage of vaccine production : from a process point of view- fermentation to purification to formulation developments; from a production point of view - from facility design to manufacturing; and from a regulatory point of view - requirements from government agencies Authors from different major pharmaceutical and biotechnology companies Describes the challenges and issues involved in vaccine production and manufacturing of the different classes of vaccines, an area not covered by other books currently on the market

Veterinary Vaccines

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Publisher : John Wiley & Sons
ISBN 13 : 1119506263
Total Pages : 350 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Veterinary Vaccines by : Samia Metwally

Download or read book Veterinary Vaccines written by Samia Metwally and published by John Wiley & Sons. This book was released on 2021-04-01 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a concise and authoritative reference on the use of vaccines against diseases of livestock Compiled by Senior Animal Health Officers at The Food and Agriculture Organization of the United Nations, and with contributions from international leading experts, Veterinary Vaccines: Principles and Applications is a concise and authoritative reference featuring easily readable reviews of the latest research in vaccinology and vaccine immune response to pathogens of major economic impact to livestock. It covers advice and recommendations for vaccine production, quality control, and effective vaccination schemes including vaccine selection, specifications, vaccination programs, vaccine handling in the field, application, failures, and assessment of herd protection. In addition, the book presents discussions on the current status and potential future developments of vaccines and vaccination against selected transboundary animal diseases. Provides a clear and comprehensive guide on using veterinary vaccines to protect livestock from diseases Teaches the principles of vaccinology and vaccine immune response Highlights the vaccine production schemes and standards for quality control testing Offers easy-to-read reviews of the most current research on the subject Gives readers advice and recommendations on which vaccination schemes are most effective Discusses the today’s state of vaccines and vaccination against selected transboundary animal diseases as well as possible future developments in the field Veterinary Vaccines: Principles and Applications is an important resource for veterinary practitioners, animal health department officials, vaccine scientists, and veterinary students. It will also be of interest to professional associations and NGO active in livestock industry.

Microbiology For Dummies

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Publisher : John Wiley & Sons
ISBN 13 : 1119544416
Total Pages : 384 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Microbiology For Dummies by : Jennifer Stearns

Download or read book Microbiology For Dummies written by Jennifer Stearns and published by John Wiley & Sons. This book was released on 2019-02-28 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiology For Dummies (9781119544425) was previously published as Microbiology For Dummies (9781118871188). While this version features a new Dummies cover and design, the content is the same as the prior release and should not be considered a new or updated product. Microbiology is the study of life itself, down to the smallest particle Microbiology is a fascinating field that explores life down to the tiniest level. Did you know that your body contains more bacteria cells than human cells? It's true. Microbes are essential to our everyday lives, from the food we eat to the very internal systems that keep us alive. These microbes include bacteria, algae, fungi, viruses, and nematodes. Without microbes, life on Earth would not survive. It's amazing to think that all life is so dependent on these microscopic creatures, but their impact on our future is even more astonishing. Microbes are the tools that allow us to engineer hardier crops, create better medicines, and fuel our technology in sustainable ways. Microbes may just help us save the world. Microbiology For Dummies is your guide to understanding the fundamentals of this enormously-encompassing field. Whether your career plans include microbiology or another science or health specialty, you need to understand life at the cellular level before you can understand anything on the macro scale. Explore the difference between prokaryotic and eukaryotic cells Understand the basics of cell function and metabolism Discover the differences between pathogenic and symbiotic relationships Study the mechanisms that keep different organisms active and alive You need to know how cells work, how they get nutrients, and how they die. You need to know the effects different microbes have on different systems, and how certain microbes are integral to ecosystem health. Microbes are literally the foundation of all life, and they are everywhere. Microbiology For Dummies will help you understand them, appreciate them, and use them.

Vaccinology

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Publisher : John Wiley & Sons
ISBN 13 : 0470656166
Total Pages : 404 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Vaccinology by : Gregg N. Milligan

Download or read book Vaccinology written by Gregg N. Milligan and published by John Wiley & Sons. This book was released on 2015-02-16 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.

Vaccine Epidemic

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Author :
Publisher : Simon and Schuster
ISBN 13 : 1626366640
Total Pages : 512 pages
Book Rating : 4.6/5 (263 download)

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Book Synopsis Vaccine Epidemic by : Louise Kuo Habakus

Download or read book Vaccine Epidemic written by Louise Kuo Habakus and published by Simon and Schuster. This book was released on 2011-02-09 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public health officials state that vaccines are safe and effective, but the truth is far more complicated. Vaccination is a serious medical intervention that always carries the potential to injure and cause death as well as to prevent disease. Coercive vaccination policies deprive people of free and informed consent—the hallmark of ethical medicine. Americans are increasingly concerned about vaccine safety and the right to make individual, informed choices together with their healthcare practitioners. Vaccine Epidemic focuses on the searing debate surrounding individual and parental vaccination choice in the United States. Habakus, Holland, and Rosenberg edit and introduce a diverse array of interrelated topics concerning the explosive vaccine controversy, including the ethics of vaccination mandates, corrupting conflicts of interest in the national vaccine program, and personal narratives of parents, children, and soldiers who have suffered vaccine injury. Newly updated with additional chapters focusing on institutional scientific misconduct, mandates for healthcare workers, concerns about HPV vaccine development, and the story behind the Supreme Court’s recent vaccine decision, Vaccine Epidemic remains the essential handbook for the vaccination choice movement and required reading for all people contemplating vaccination for themselves and their children.

Biotechnology for Beginners

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Publisher : Academic Press
ISBN 13 : 0323855709
Total Pages : 476 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Biotechnology for Beginners by : Reinhard Renneberg

Download or read book Biotechnology for Beginners written by Reinhard Renneberg and published by Academic Press. This book was released on 2023-01-16 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology for Beginners, Third Edition presents the latest developments in the evolving field of biotechnology which has grown to such an extent over the past few years that increasing numbers of professional’s work in areas that are directly impacted by the science. This book offers an exciting and colorful overview of biotechnology for professionals and students in a wide array of the life sciences, including genetics, immunology, biochemistry, agronomy and animal science. This book will also appeals to lay readers who do not have a scientific background but are interested in an entertaining and informative introduction to the key aspects of biotechnology. Authors Renneberg and Loroch discuss the opportunities and risks of individual technologies and provide historical data in easy-to-reference boxes, highlighting key topics. The book covers all major aspects of the field, from food biotechnology to enzymes, genetic engineering, viruses, antibodies, and vaccines, to environmental biotechnology, transgenic animals, analytical biotechnology, and the human genome. Covers the whole of biotechnology Presents an extremely accessible style, including lavish and humorous illustrations throughout Includes new chapters on CRISPR cas-9, COVID-19, the biotechnology of cancer, and more

The Vaccine Book

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Author :
Publisher : Little, Brown Spark
ISBN 13 : 0316213632
Total Pages : 226 pages
Book Rating : 4.3/5 (162 download)

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Book Synopsis The Vaccine Book by : Robert W. Sears

Download or read book The Vaccine Book written by Robert W. Sears and published by Little, Brown Spark. This book was released on 2011-10-26 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: ***COMPLETELY REVISED AND UPDATED IN 2019*** ***New Covid Chapter Added in 2023*** The Vaccine Book offers parents a fair, impartial, fact-based resource from the most trusted name in pediatrics. Dr. Bob devotes each chapter in the book to a disease/vaccine pair and offers a comprehensive discussion of what the disease is, how common or rare it is, how serious or harmless it is, the ingredients of the vaccine, and any possible side effects from the vaccine. This completely revised edition offers: Updated information on each vaccine and disease More detail on vaccines' side effects Expanded discussions of combination vaccines A new section on adult vaccines Additional options for alternative vaccine schedules A guide to Canadian vaccinations The Vaccine Book provides exactly the information parents want and need as they make their way through the vaccination maze.

Vaccines and Autoimmunity

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Publisher : John Wiley & Sons
ISBN 13 : 1118663438
Total Pages : 394 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Vaccines and Autoimmunity by : Yehuda Shoenfeld

Download or read book Vaccines and Autoimmunity written by Yehuda Shoenfeld and published by John Wiley & Sons. This book was released on 2015-07-07 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.

You Wouldn't Want to Live Without Insects!

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Author :
Publisher : The Salariya Book Company
ISBN 13 : 1910184586
Total Pages : 40 pages
Book Rating : 4.9/5 (11 download)

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Book Synopsis You Wouldn't Want to Live Without Insects! by : Anne Rooney

Download or read book You Wouldn't Want to Live Without Insects! written by Anne Rooney and published by The Salariya Book Company. This book was released on 2021-02-02 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nasty stinging creatures that destroy crops and spread disease – if that's your opinion of insects, read this fascinating book to discover the other side of the story. Without insects to pollinate flowers, we would have no fruit. Without bees, we would have no honey. Maggots are not pretty, but they help to make the world a cleaner and healthier place. You Wouldn’t Want to Live Without Insects! is part of a brand-new science and technology strand within the internationally acclaimed You Wouldn’t Want to Be series. The clear, engaging text and humorous illustrations bring the subject to life and stimulate young readers' curiosity about the world around them. Specially commissioned cartoon-style illustrations in full colour make these books attractive and accessible even to reluctant readers. Information is conveyed through captions, labels and humorous speech bubbles in addition to the main text. Illustrated sidebars headed ‘How It Works’, ‘Top Tip’ or ‘You Can Do It’ supply more facts, describe simple, safe experiments, or steps that readers can take to help make the world a better place. Each volume includes a timeline and a list of ‘Did You Know?’ facts.

Birth Plans For Dummies

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118432134
Total Pages : 412 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Birth Plans For Dummies by : Rachel Gurevich

Download or read book Birth Plans For Dummies written by Rachel Gurevich and published by John Wiley & Sons. This book was released on 2012-10-09 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: The easy, trusted way to develop a birth plan As an expectant mother and parent, navigating all of the information and options for labor and delivery can be cumbersome and confusing. Birth Plans For Dummies, is the ultimate resource guide to help you understand, develop, and implement a plan for the birth of your baby. A birth plan is a communication tool for expectant mothers and those involved in the delivery of a child. The plan explains the mother's preferences for labor and delivery and eliminates any confusion. There are a wide variety of methods, strategies, and techniques available to pregnant women preparing for delivery—and this hands-on, friendly guide covers them all. Covers choosing the setting and method that best fits the mothers needs and wishes Informs expectant parents about the numerous pain management and labor intervention options Provides instruction on developing and writing a birth plan and putting it into action If you are an expectant mother or parent looking for a guide to help develop a plan for the birth of your child, then Birth Plans For Dummies is the perfect book for you.

Crohn's and Colitis For Dummies

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 111987579X
Total Pages : 343 pages
Book Rating : 4.1/5 (198 download)

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Book Synopsis Crohn's and Colitis For Dummies by : Tauseef Ali

Download or read book Crohn's and Colitis For Dummies written by Tauseef Ali and published by John Wiley & Sons. This book was released on 2022-09-19 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get relief from your inflammatory bowel disease symptoms Crohn’s disease and ulcerative colitis are diseases that disrupt your body’s ability to digest food, absorb nutrition, and eliminate waste in a healthy manner. Crohn’s And Colitis For Dummies is the ultimate reference to these common forms of inflammatory bowel disease (IBD), including tips on how to recognize and control the symptoms, so you can get your life back. Get ideas for keeping disease in check through diet and lifestyle changes, learn about the various medical and surgical treatment options, and discover healthier living with this friendly Dummies guide. This updated edition covers the latest research on IBD and new therapies that are helping today’s Crohn’s and colitis patients. You’ll also find resources that will help and offer hope as you navigate your diagnosis. Learn about the different forms of inflammatory bowel disease Ask the right questions at the doctor’s office Make simple changes that will improve your symptoms Know that there’s hope and that you are not alone This book is perfect for anyone who has been recently diagnosed with Crohn’s or colitis, and for those who suspect they may have an IBD. If you’re a caregiver or family member of an IBD sufferer, you’ll also love the easy-to-understand information inside.

Raising Goats For Dummies

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Publisher : John Wiley & Sons
ISBN 13 : 0470633808
Total Pages : 360 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Raising Goats For Dummies by : Cheryl K. Smith

Download or read book Raising Goats For Dummies written by Cheryl K. Smith and published by John Wiley & Sons. This book was released on 2010-01-28 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to raise goats and start reaping the benefits of owning these fun and useful animals Raising goats is a major part of human life (and survival) around the world. The movement has increased in popularity in recent years as consumers embrace a more sustainable lifestyle, reject commercialism, move to organic food options, and raise concerns about industrial agriculture practices. Raising Goats For Dummies provides you with an introduction to all aspects of owning, caring for, and the day-to-day benefits of raising goats. Breaks down the complicated process of choosing and purchasing the right goat breed to meet your needs and getting facilities for your goat set up. Provides in-depth information on proper grooming, handling, feeding, and milking Covers the basics of goat health and nutrition Offers tips and advice for using your goat to produce milk, meat, fiber, and more You'll quickly understand what makes these useful and delightful creatures so popular and gain the knowledge and skills to properly care for and utilize their many offerings with help from Raising Goats For Dummies.

The Vaccine Book

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Author :
Publisher : Academic Press
ISBN 13 : 012805400X
Total Pages : 664 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Vaccine Book by : Barry R. Bloom

Download or read book The Vaccine Book written by Barry R. Bloom and published by Academic Press. This book was released on 2016-06-23 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy

Vaccinology

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1405185740
Total Pages : 552 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Vaccinology by : W. John W. Morrow

Download or read book Vaccinology written by W. John W. Morrow and published by John Wiley & Sons. This book was released on 2012-09-04 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering all aspects of vaccine research and development in one volume, this authoritative resource takes a comprehensive and systematic approach to the science of vaccinology focusing not only on basic science, but also on the many stages required to commercialize and navigate the regulatory requirements for human application, both in the United States and Europe. Reviews in detail the process of designing a vaccine, from the initial stages of antigen discovery to human application Includes evaluation of vaccine efficacy and safety Details clinical trial design, including regulatory requirements Discusses the emerging field of active cellular immunotherapy Vaccinology: Principles and Practice provides an invaluable resource for clinicians, scientific and medical researchers, lecturers and postdoctoral fellows working in the field of vaccines.

Who Doesn’t Want to be Vaccinated? Determinants of Vaccine Hesitancy During COVID-19

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Author :
Publisher : International Monetary Fund
ISBN 13 : 1513573713
Total Pages : 41 pages
Book Rating : 4.5/5 (135 download)

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Book Synopsis Who Doesn’t Want to be Vaccinated? Determinants of Vaccine Hesitancy During COVID-19 by : Hibah Khan

Download or read book Who Doesn’t Want to be Vaccinated? Determinants of Vaccine Hesitancy During COVID-19 written by Hibah Khan and published by International Monetary Fund. This book was released on 2021-05-06 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quick vaccine rollouts are crucial for a strong economic recovery, but vaccine hesitancy could prolong the pandemic and the need for social distancing and lockdowns. We use individual-level data from nationally representative surveys developed by YouGov and Imperial College London to empirically examine the determinants of vaccine hesitancy across 17 countries and over time. Vaccine demand depends on demographic features such as age and gender, but also on perceptions about the severity of COVID-19 and side effects of the vaccine, vaccine access, compliance with protective behaviors, overall trust in government, and how information is shared with peers. We then introduce vaccine hesitancy into an extended SIR model to assess its impact on pandemic dynamics. We find that hesitancy can increase COVID-19 infections and deaths significantly if it slows down vaccine rollouts, but has a smaller impact if all willing adults can be immunized rapidly.