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How To Make A Vaccine
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Book Synopsis How to Make a Vaccine by : John Rhodes
Download or read book How to Make a Vaccine written by John Rhodes and published by University of Chicago Press. This book was released on 2021-04-12 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Distinguished expert in vaccine development John Rhodes tells the story of the first approved COVID-19 vaccines and offers an essential, up-to-the-minute primer on how scientists discover, test, and distribute vaccines. As the COVID-19 pandemic has affected every corner of the world, changing our relationship to our communities, to our jobs, and to each other, the most pressing question has been—when will it end? Researchers around the globe are urgently trying to answer this question by racing to test and distribute a vaccine that could end the greatest public health threat of our time. In How to Make a Vaccine, an expert who has firsthand experience developing vaccines tells an optimistic story of how three hundred years of vaccine discovery and a century and a half of immunology research have come together at this powerful moment—and will lead to multiple COVID-19 vaccines. Dr. John Rhodes draws on his experience as an immunologist, including working alongside a young Anthony Fauci, to unravel the mystery of how vaccines are designed, tested, and produced at scale for global deployment. Concise and accessible, this book describes in everyday language how the immune system evolved to combat infection, how viruses responded by evolving ways to evade our defenses, and how vaccines do their work. That history, and the pace of current research developments, make Rhodes hopeful that multiple vaccines will protect us. Today the complex workings of the immune system are well understood. The tools needed by biomedical scientists stand ready to be used, and more than 160 vaccine candidates have already been produced. But defeating COVID-19 won’t be the end of the story: Rhodes describes how discoveries today are also empowering scientists to combat future threats to global health, including a recent breakthrough in the development of genetic vaccines, which have never before been used in humans. As the world prepares for a vaccine, Rhodes offers a current and informative look at the science and strategies that deliver solutions to the crisis.
Book Synopsis Epidemiology and Prevention of Vaccine-Preventable Diseases, 13th Edition E-Book by : Jennifer Hamborsky, MPH, MCHES
Download or read book Epidemiology and Prevention of Vaccine-Preventable Diseases, 13th Edition E-Book written by Jennifer Hamborsky, MPH, MCHES and published by Public Health Foundation. This book was released on 2015-10-19 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Public Health Foundation (PHF) in partnership with the Centers for Disease Control and Prevention (CDC) is pleased to announce the availability of Epidemiology and Prevention of Vaccine-Preventable Diseases, 13th Edition or “The Pink Book” E-Book. This resource provides the most current, comprehensive, and credible information on vaccine-preventable diseases, and contains updated content on immunization and vaccine information for public health practitioners, healthcare providers, health educators, pharmacists, nurses, and others involved in administering vaccines. “The Pink Book E-Book” allows you, your staff, and others to have quick access to features such as keyword search and chapter links. Online schedules and sources can also be accessed directly through e-readers with internet access. Current, credible, and comprehensive, “The Pink Book E-Book” contains information on each vaccine-preventable disease and delivers immunization providers with the latest information on: Principles of vaccination General recommendations on immunization Vaccine safety Child/adult immunization schedules International vaccines/Foreign language terms Vaccination data and statistics The E-Book format contains all of the information and updates that are in the print version, including: · New vaccine administration chapter · New recommendations regarding selection of storage units and temperature monitoring tools · New recommendations for vaccine transport · Updated information on available influenza vaccine products · Use of Tdap in pregnancy · Use of Tdap in persons 65 years of age or older · Use of PCV13 and PPSV23 in adults with immunocompromising conditions · New licensure information for varicella-zoster immune globulin Contact [email protected] for more information. For more news and specials on immunization and vaccines visit the Pink Book's Facebook fan page
Book Synopsis Opportunities in Biotechnology for Future Army Applications by : National Research Council
Download or read book Opportunities in Biotechnology for Future Army Applications written by National Research Council and published by National Academies Press. This book was released on 2001-07-11 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report surveys opportunities for future Army applications in biotechnology, including sensors, electronics and computers, materials, logistics, and medical therapeutics, by matching commercial trends and developments with enduring Army requirements. Several biotechnology areas are identified as important for the Army to exploit, either by direct funding of research or by indirect influence of commercial sources, to achieve significant gains in combat effectiveness before 2025.
Book Synopsis The Children's Vaccine Initiative by : Institute of Medicine
Download or read book The Children's Vaccine Initiative written by Institute of Medicine and published by National Academies Press. This book was released on 1993-02-01 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Children's Vaccine Initiative is an international endeavor to ensure that children throughout the world are immunized. This book notes that one of the best opportunities to address the growing problem of immunization in the United States and to improve the health of children in developing countries lies in marshaling the vaccine development and production efforts in the United States and abroad. The book contains information on the nature and status of vaccine development and production efforts in the United States and abroad, and it recommends ways to enhance participation in the International Children's Vaccine Initiative.
Book Synopsis Practical Aspects of Vaccine Development by : Parag Kolhe
Download or read book Practical Aspects of Vaccine Development written by Parag Kolhe and published by Elsevier. This book was released on 2021-09-08 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Formulation, Development and Manufacturing of Vaccines: The Practical Aspects provides an industry perspective on vaccine product development and manufacture that covers their formulation development, manufacture and delivery/in-use considerations of vaccine production. With the increasing complexity of vaccine products in development, there is a need for a comprehensive review of the current state of the industry and its challenges. While formulation scientists working in biotherapeutic development may be familiar with proteins, vaccines present unique challenges, including the wide range of vaccine components that may comprise proteins, polysaccharides, protein-polysaccharide conjugates, adjuvants, etc. and the varying stability and behavior of solution- and suspension-based systems. This book is an essential resource for formulation scientists, researchers in vaccine development throughout medical and life sciences, and advanced students. Includes formulation considerations for various vaccine types, including proteins, polysaccharides, conjugates and live vaccines Considers process development for solution, suspension and lyophilized products Explores the future potential of vaccines, including multi-component vaccines and novel delivery mechanisms/devices
Book Synopsis Computer-Aided Vaccine Design by : Joo Chuan Tong
Download or read book Computer-Aided Vaccine Design written by Joo Chuan Tong and published by Elsevier. This book was released on 2013-07-31 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. Chapters include: MHC and T cell responses; Immunoglobulins and B cell responses; Scientific publications and databases; Database design; Computational T cell vaccine design; Computational B cell vaccine design; infectious disease informatics; Vaccine safety and quality assessments; and Vaccine adjuvant informatics. Essential reading for any biologist who wants to understand methods of computer-aided vaccine design Description of available data sources and publicly available software, with detailed analysis of strengths and weaknesses Theoretical concepts and practical examples of database design and development for a virtual screening campaign
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :030968224X Total Pages :273 pages Book Rating :4.3/5 (96 download)
Book Synopsis Framework for Equitable Allocation of COVID-19 Vaccine by : National Academies of Sciences, Engineering, and Medicine
Download or read book Framework for Equitable Allocation of COVID-19 Vaccine written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-11-30 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the coronavirus disease 2019 (COVID-19) pandemic and the societal disruption it has brought, national governments and the international community have invested billions of dollars and immense amounts of human resources to develop a safe and effective vaccine in an unprecedented time frame. Vaccination against this novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), offers the possibility of significantly reducing severe morbidity and mortality and transmission when deployed alongside other public health strategies and improved therapies. Health equity is intertwined with the impact of COVID-19 and there are certain populations that are at increased risk of severe illness or death from COVID-19. In the United States and worldwide, the pandemic is having a disproportionate impact on people who are already disadvantaged by virtue of their race and ethnicity, age, health status, residence, occupation, socioeconomic condition, or other contributing factors. Framework for Equitable Allocation of COVID-19 Vaccine offers an overarching framework for vaccine allocation to assist policy makers in the domestic and global health communities. Built on widely accepted foundational principles and recognizing the distinctive characteristics of COVID-19, this report's recommendations address the commitments needed to implement equitable allocation policies for COVID-19 vaccine.
Author :Centers for Disease Control and Prevention CDC Publisher :Oxford University Press ISBN 13 :0190628634 Total Pages :672 pages Book Rating :4.1/5 (96 download)
Book Synopsis CDC Yellow Book 2018: Health Information for International Travel by : Centers for Disease Control and Prevention CDC
Download or read book CDC Yellow Book 2018: Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.
Book Synopsis The Vaccine Book by : Barry R. Bloom
Download or read book The Vaccine Book written by Barry R. Bloom and published by Academic Press. This book was released on 2016-06-23 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy
Book Synopsis Vaccine Supply and Innovation by : National Research Council
Download or read book Vaccine Supply and Innovation written by National Research Council and published by National Academies Press. This book was released on 1985-02-01 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United States is facing a vaccine shortage that may threaten public health. This book examines vaccine research and development, production and supply, and utilization and offers recommendations aimed at ensuring vaccine supply and promoting innovation. In addition, this comprehensive volume provides information on the adverse reactions associated with the range of vaccines used in the United States and contains the most thorough analysis ever published on the state of the law regarding vaccine-related injury and compensation for vaccine injury.
Book Synopsis Vaccine Analysis: Strategies, Principles, and Control by : Brian K. Nunnally
Download or read book Vaccine Analysis: Strategies, Principles, and Control written by Brian K. Nunnally and published by Springer. This book was released on 2014-11-27 with total page 665 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.
Book Synopsis A Shot to Save the World by : Gregory Zuckerman
Download or read book A Shot to Save the World written by Gregory Zuckerman and published by Penguin. This book was released on 2021-10-26 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: "An inspiring and informative page-turner." –Walter Isaacson Longlisted for the FT/McKinsey Business Book of the Year Award The authoritative account of the race to produce the vaccines that are saving us all, from the #1 New York Times bestselling author of The Man Who Solved the Market Few were ready when a mysterious respiratory illness emerged in Wuhan, China in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization. A French businessman dismissed by many as a fabulist. A Turkish immigrant with little virus experience. A quirky Midwesterner obsessed with insect cells. A Boston scientist employing questionable techniques. A British scientist despised by his peers. Far from the limelight, each had spent years developing innovative vaccine approaches. Their work was met with skepticism and scorn. By 2020, these individuals had little proof of progress. Yet they and their colleagues wanted to be the ones to stop the virus holding the world hostage. They scrambled to turn their life’s work into life-saving vaccines in a matter of months, each gunning to make the big breakthrough—and to beat each other for the glory that a vaccine guaranteed. A #1 New York Times bestselling author and award-winning Wall Street Journal investigative journalist lauded for his “bravura storytelling” (Gary Shteyngart) and “first-rate” reporting (The New York Times), Zuckerman takes us inside the top-secret laboratories, corporate clashes, and high-stakes government negotiations that led to effective shots. Deeply reported and endlessly gripping, this is a dazzling, blow-by-blow chronicle of the most consequential scientific breakthrough of our time. It’s a story of courage, genius, and heroism. It’s also a tale of heated rivalries, unbridled ambitions, crippling insecurities, and unexpected drama. A Shot to Save the World is the story of how science saved the world.
Book Synopsis Vaccines for the 21st Century by : Institute of Medicine
Download or read book Vaccines for the 21st Century written by Institute of Medicine and published by National Academies Press. This book was released on 2001-02-21 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.
Book Synopsis The Vaccine Book by : Robert W. Sears
Download or read book The Vaccine Book written by Robert W. Sears and published by Little, Brown Spark. This book was released on 2011-10-26 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: ***COMPLETELY REVISED AND UPDATED IN 2019*** ***New Covid Chapter Added in 2023*** The Vaccine Book offers parents a fair, impartial, fact-based resource from the most trusted name in pediatrics. Dr. Bob devotes each chapter in the book to a disease/vaccine pair and offers a comprehensive discussion of what the disease is, how common or rare it is, how serious or harmless it is, the ingredients of the vaccine, and any possible side effects from the vaccine. This completely revised edition offers: Updated information on each vaccine and disease More detail on vaccines' side effects Expanded discussions of combination vaccines A new section on adult vaccines Additional options for alternative vaccine schedules A guide to Canadian vaccinations The Vaccine Book provides exactly the information parents want and need as they make their way through the vaccination maze.
Book Synopsis Vaccines for Veterinarians E-Book by : Ian R Tizard
Download or read book Vaccines for Veterinarians E-Book written by Ian R Tizard and published by Elsevier Health Sciences. This book was released on 2019-11-19 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Both a theoretical text and a practical handbook, Vaccines for Veterinarians is the first of its kind to bring the basic science of animal vaccination and the practical details of vaccine use together in one single volume. From the first chapter on the history of vaccination and the triumph of rinderpest eradication to the last chapter on the rapidly emerging field of cancer vaccines, this book offers a truly comprehensive grounding in established and emerging vaccines for both major and minor species. Specific topics include viral vectored vaccines, DNA-plasmid vaccines, RNA vaccines, reverse vaccinology, the complexities of adjuvant use, vaccine failures and adverse events, vaccine production and regulation, robotic vaccination machines, contraceptive and production-enhancing vaccines, and so much more. At a time when resistance to human vaccination is receiving much publicity, this evidence-based book is the ideal counter to ill-informed speculation — serving as a timely reminder that vaccination is essential for the control of infectious diseases in animals. Well-respected and experienced veterinary author, Ian Tizard, provides expert guidance on the topic of vaccinations and immunology in veterinary medicine. Expert Consult site offers an online version of the book, making it easy to search the entire book electronically. The latest information on viral vectored vaccines keeps you up-to-date on the topic as well as the properties and relative advantages of currently used vectors in animal vaccines. Survey of vaccine responses covers the different mechanisms by which the immune system responds to different types of vaccines. Inclusion of the latest vaccine technologies discusses the advantages and disadvantages of DNA-plasmid vaccines, RNA vaccines, and more. Coverage of adverse events and hypersensitivities includes the best ways to treat them and report them. Coverage of passive immunization discusses the growing use of therapeutic monoclonal antibodies in veterinary medicine. Coverage of immunotherapy includes recent improvements and new products in both active and passive immunotherapy against animal cancers.
Book Synopsis History of Vaccine Development by : Stanley A. Plotkin
Download or read book History of Vaccine Development written by Stanley A. Plotkin and published by Springer Science & Business Media. This book was released on 2011-05-11 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. This book covers the history of the methodological progress in vaccine development and to the social and ethical issues raised by vaccination. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines." Contributing authors include pioneers in the field, such as Samuel L. Katz and Hilary Koprowski. This history of vaccines is relatively short and many of its protagonists are still alive. This book was written by some of the chief actors in the drama whose subject matter is the conquest of epidemic disease.
Book Synopsis Vaccine Epidemic by : Louise Kuo Habakus
Download or read book Vaccine Epidemic written by Louise Kuo Habakus and published by Simon and Schuster. This book was released on 2011-02-09 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public health officials state that vaccines are safe and effective, but the truth is far more complicated. Vaccination is a serious medical intervention that always carries the potential to injure and cause death as well as to prevent disease. Coercive vaccination policies deprive people of free and informed consent—the hallmark of ethical medicine. Americans are increasingly concerned about vaccine safety and the right to make individual, informed choices together with their healthcare practitioners. Vaccine Epidemic focuses on the searing debate surrounding individual and parental vaccination choice in the United States. Habakus, Holland, and Rosenberg edit and introduce a diverse array of interrelated topics concerning the explosive vaccine controversy, including the ethics of vaccination mandates, corrupting conflicts of interest in the national vaccine program, and personal narratives of parents, children, and soldiers who have suffered vaccine injury. Newly updated with additional chapters focusing on institutional scientific misconduct, mandates for healthcare workers, concerns about HPV vaccine development, and the story behind the Supreme Court’s recent vaccine decision, Vaccine Epidemic remains the essential handbook for the vaccination choice movement and required reading for all people contemplating vaccination for themselves and their children.
