Regulation of the Growth of Human Breast Cancer Cells by the Angiotensin II Receptor AT2

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Publisher :
ISBN 13 :
Total Pages : 88 pages
Book Rating : 4.:/5 (598 download)

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Book Synopsis Regulation of the Growth of Human Breast Cancer Cells by the Angiotensin II Receptor AT2 by : Sucharitha Balasubramaniam

Download or read book Regulation of the Growth of Human Breast Cancer Cells by the Angiotensin II Receptor AT2 written by Sucharitha Balasubramaniam and published by . This book was released on 2004 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Exploration of the Regulation of Breast Cancer by the Angiotensin II Receptor AT2

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Publisher :
ISBN 13 :
Total Pages : 8 pages
Book Rating : 4.:/5 (742 download)

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Book Synopsis Exploration of the Regulation of Breast Cancer by the Angiotensin II Receptor AT2 by :

Download or read book Exploration of the Regulation of Breast Cancer by the Angiotensin II Receptor AT2 written by and published by . This book was released on 2002 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: Overexpression of ErbB2 and ErbB3 receptors, members of the ErbB receptor family, are correlated to the transformation of breast, ovarian and many other cell types into malignant tumors. This involvement of the ErbB receptor family in the control of cell proliferation and its role in human malignancies has led to intense studies of these receptors and their regulatory mechanisms. The ErbB family is consisted of four homologous members, the EGFR or ErbBl, ErbB2, ErbB3 and ErbB4, and these molecules can homodimerize or heterodimerize and activate growth-promoting signaling in response to binding of a number of structurally similar growth factors. This situation makes regulation of growth-promoting signaling by ErbB family receptors in cancer very complex. Identification of a mechanism to regulate growth-promoting cell signaling by these receptors may lead to the development of effective treatments to inhibit tumor growth in breast and ovarian cancer types that show ErbB2 and ErbB3 receptor overexpression.

The Cancer Stem Cell Niche

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Publisher : Academic Press
ISBN 13 : 0323853250
Total Pages : 246 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis The Cancer Stem Cell Niche by : Susie Nilsson

Download or read book The Cancer Stem Cell Niche written by Susie Nilsson and published by Academic Press. This book was released on 2021-02-09 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cancer Stem Cell Niche, Volume Five in the Advances in Stem Cells and their Niches series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Acute lymphoblastic leukemia and the bone marrow microenvironment, Stem cell niches in bone and their roles in cancer metastasis, The role of vasculature in cancer stem cell niches, The lung cancer stem cell niche, The prostate cancer stem cell niche: Genetic drivers and therapeutic approaches, Impact of prostate cancer stem cell niches on prostate cancer tumorigenesis and progression, The testicular cancer stem cell niche. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Stem Cells and their Niches series Includes the latest information on the Cancer Stem Cell Niche

Frontiers in Research of the Renin-Angiotensin System on Human Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 1402063725
Total Pages : 310 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Frontiers in Research of the Renin-Angiotensin System on Human Disease by : Po Sing Leung

Download or read book Frontiers in Research of the Renin-Angiotensin System on Human Disease written by Po Sing Leung and published by Springer Science & Business Media. This book was released on 2007-10-16 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary aim of this book is to provide a topical and timely forum for the critical appraisal of an area of renin-angiotensin system (RAS) research that is expanding rapidly. In this respect, a collection of thirteen chapters from distinguished and world-class experts in the field has been presented on the contemporary research of the RAS and their implications in human disease. This book is an indispensable tool tailor-made for specialists, non-specialists and the novice.

The Protective Arm of the Renin Angiotensin System (RAS)

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Publisher : Academic Press
ISBN 13 : 0128014857
Total Pages : 312 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Protective Arm of the Renin Angiotensin System (RAS) by : Thomas Unger

Download or read book The Protective Arm of the Renin Angiotensin System (RAS) written by Thomas Unger and published by Academic Press. This book was released on 2015-04-18 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin–angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Focusing on recent research, The Protective Arm of the Renin Angiotensin System presents a host of new experimental studies on specific components of the RAS, namely angiotensin AT2 receptors (AT2R), the angiotensin (1–7) peptide with its receptor Mas, and the enzyme ACE 2, which exert significant beneficial, health-promoting actions by counterbalancing the well-known harmful arm of the RAS with its classical angiotensin AT1 receptor. This innovative concept of the protective arm of the RAS, examined in this reference, represents an indispensable background and will be a strong support for biomedical students, researchers, cardiologists, surgeons, nephrologists, diabetologists, and endocrinologists, as well as any other physician or researcher concerned with RAS physiology, pathophysiology and clinical implications. - Provides a complete understanding of the protective side of the Renin Angiotensin System (RAS) involving angiotensin AT2 receptor, ACE2, and Ang(1-7)/Mas receptor - Combines the knowledge of editors who pioneered research on the protective renin angiotensin system including; Dr. Thomas Unger, one of the founders of AT2 receptor research; Dr. Ulrike M. Steckelings, who contributed significantly to first preclinical studies with a novel specific AT2-agonist, and Dr. Robson Santos who pioneered research on angiotensin-(1-7) and its receptor Mas. - Shows that the protective RAS axes are able to ameliorate the course of several cardiovascular, renal, metabolic and neurological diseases - Provides the basis for the understanding of a novel therapeutic approach to stimulate components of the protective arm of the RAS.

Angiotensin Vol. I

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540406402
Total Pages : 576 pages
Book Rating : 4.4/5 (64 download)

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Book Synopsis Angiotensin Vol. I by : E. M. Abdel-Rahman

Download or read book Angiotensin Vol. I written by E. M. Abdel-Rahman and published by Springer Science & Business Media. This book was released on 2004-03-31 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: with contributions by numerous experts

Handbook of Biologically Active Peptides

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Publisher : Elsevier
ISBN 13 : 0080463797
Total Pages : 1682 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Handbook of Biologically Active Peptides by : Abba Kastin

Download or read book Handbook of Biologically Active Peptides written by Abba Kastin and published by Elsevier. This book was released on 2011-04-28 with total page 1682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for individuals ranging from peptide researchers, to biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and to endocrinologists. Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas with which they would not ordinarily be familiar.*Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas that they would not ordinarily be familiar.*Fascinating relationships described in the book include the presence of some peptides originally found in frog skin that persist in the human human and brain where they can affect food intake and obesity.

Control of Gene Expression by Catecholamines and the Renin-Angiotensin System

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792379812
Total Pages : 252 pages
Book Rating : 4.3/5 (798 download)

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Book Synopsis Control of Gene Expression by Catecholamines and the Renin-Angiotensin System by : Heinz Rupp

Download or read book Control of Gene Expression by Catecholamines and the Renin-Angiotensin System written by Heinz Rupp and published by Springer Science & Business Media. This book was released on 2000-11-30 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The special issue of Molecular and Cellular Biochemistry focuses on `Control of Gene Expression by Catecholamines and the Renin-Angiotensin System' in health and disease. In recent years, great progress has been made in the understanding of catecholamine and angiotensin II modulated gene expression. There is also increasing evidence that catecholamine and angiotensin II induced cellular injury not solely arises from classical pathways but also from a perturbed gene expression. Taking into account that catecholamines and angiotensin II are vital for a balanced gene expression of many cells, the intriguing possibility arises that various disease are initiated or aggravated by such an imbalance. Catecholamine and angiotensin II influences can be in excess arising from, for example, hypercaloric food intake or psychosocial stress. During early progression of heart failure, sympathetic activity and angiotensin II influences also become increased. Due to beta-adrenergic receptor downregulation, depressed catecholamine influences are expected in the final stage of heart failure. An imbalanced influence of catecholamines and angiotensin II on gene expression leads to disordered molecular structures of the cell and an impaired cell function. This focused issue is organized into chapters concentrating on catecholamines, angiotensin II, and the interaction between catecholamines and angiotensin II. Basic biochemical processes are covered in detail and the potential of these pathways for explaining chronic diseases associated with excess catecholamine and angiotensin II influences should become apparent. It is hoped that this focussed issue triggers novel research into the development of drugs that are targeted at diseases characterized by an imbalanced gene expression involving catecholamines and angiotensin II.

The Ohio Journal of Science

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ISBN 13 :
Total Pages : 238 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Ohio Journal of Science by :

Download or read book The Ohio Journal of Science written by and published by . This book was released on 2005 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes book reviews and abstracts.

Nephrology and Fluid/Electrolyte Physiology

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323568777
Total Pages : 472 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Nephrology and Fluid/Electrolyte Physiology by : William Oh

Download or read book Nephrology and Fluid/Electrolyte Physiology written by William Oh and published by Elsevier Health Sciences. This book was released on 2018-06-25 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Richard Polin's Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today's practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. - Stay fully up to date in this fast-changing field with Nephrology and Fluid/Electrolyte Physiology, 3rd Edition. - New chapters on Inherited Disorders of Calcium, Phosphate and Magnesium; Fluid and Electrolyte Management of High Risk Infants; Renal Development and Molecular Pathogenesis of Renal Dysplasia; and Prenatal Programming, which describes how prenatal insults can result in hypertension, kidney and cardiovascular disease. - The most current clinical information, including new content on the molecular basis for hereditary tubulopathies and inherited disorders of calcium, phosphate, and magnesium homeostasis. - New information on genetics and pharmacology, neonatal hypertension, diuretic use in the newborn, prenatal programming of adult diseases, lung fluid balance, and much more. - Consistent chapter organization to help you find information quickly and easily. - The most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. Purchase each volume individually, or get the entire 7-volume set!Gastroenterology and NutritionHematology, Immunology and GeneticsHemodynamics and CardiologyInfectious Disease and Pharmacology New Volume!Nephrology and Fluid/Electrolyte PhysiologyNeurologyThe Newborn Lung

Respiratory Regulation - The Molecular Approach

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Publisher : Springer Science & Business Media
ISBN 13 : 9400745486
Total Pages : 353 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Respiratory Regulation - The Molecular Approach by : Mieczyslaw Pokorski

Download or read book Respiratory Regulation - The Molecular Approach written by Mieczyslaw Pokorski and published by Springer Science & Business Media. This book was released on 2012-07-27 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, an international collaborative effort in the area of molecular respiratory research, showcases a broad range of multidisciplinary approaches to unravel and analyze the underlying mechanisms of a spectrum of respiratory ailments. It discusses immunological and genetic respiratory disorders, cancer, respiratory allergies and cough, sleep disordered breathing and many others. Exciting new results and up-to-date critical overviews of widely debated topics pertaining to respiratory disorders are presented. The contributions provide evidence for the growing interest of the international community of researchers in the field of respiration. The book incorporates modern molecular approaches to diagnostic and treatment solutions, underscoring the need for rational, evidence-based treatment methods. Combining cutting edge basic and clinical research with expert knowledge and experience this book is essential reading for medical students, research scientists and practicing specialists in pulmonology, immunology and allergology.

Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 2292 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Topics in Anti-Cancer Research

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Publisher : Bentham Science Publishers
ISBN 13 : 1608051366
Total Pages : 561 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Topics in Anti-Cancer Research by : Atta-ur Rahman

Download or read book Topics in Anti-Cancer Research written by Atta-ur Rahman and published by Bentham Science Publishers. This book was released on 2013-07-31 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second volume of the Patent eBook Series titled Topics in Anti-Cancer Research. The eBook includes updated chapters on topics relevant to contemporary cancer research published in the journal, Recent Patents on Anti-Cancer Drug Discovery. This volume covers scientific and patented novel chemotherapeutic agents and drugs for metastatic castration-resistant prostate cancer and Ras/ Raf /MEK/ERK pathway, P1K, AKT and mTORC1/2 inhibitors, ATPase inhibitors for cancer therapy, and sphingomyelin biosynthesis which regulates cancer cell death and growth. Other chapters also explain research on biochemical regulation i.e. cell cycle and energy metabolism, the role of genetic variations of FcγRs gamma receptors in monoclonal antibody based anti-cancer therapy and effectiveness of antiangiogenic therapy, endogenous angiogenesis inhibitors and anti-angiogenic drugs for the treatment of renal cell carcinoma, prevention of cancer by ribonucleotide reductase, anticancer activity of Erlotinib in glioblastoma and the mechanisms of action of nanodrugs and nano-sized camptothecin drugs in cancer chemotherapy. The volume also covers recent studies in the field of onconutrition. The broad range of topics covered in this second volume will be of immense interest to clinicians, scientists and R&D experts seeking new targets for the prevention of cancer, novel oncogenic biomarkers, and methods for cancer therapy.

Encyclopedia of Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 3540368477
Total Pages : 3307 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Encyclopedia of Cancer by : Manfred Schwab

Download or read book Encyclopedia of Cancer written by Manfred Schwab and published by Springer Science & Business Media. This book was released on 2008-09-23 with total page 3307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.

The Renin Angiotensin System in Cancer, Lung, Liver and Infectious Diseases

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Publisher : Springer Nature
ISBN 13 : 3031236211
Total Pages : 499 pages
Book Rating : 4.0/5 (312 download)

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Book Synopsis The Renin Angiotensin System in Cancer, Lung, Liver and Infectious Diseases by : Sukhwinder K. Bhullar

Download or read book The Renin Angiotensin System in Cancer, Lung, Liver and Infectious Diseases written by Sukhwinder K. Bhullar and published by Springer Nature. This book was released on 2023-03-14 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book of the series on “Advances in Biochemistry in Health and Disease” includes state-of-the-art information on the status of renin-angiotensin system (RAS) in the form of 24 chapters. This book has been organized into three sections: (i) General Implications of RAS in human health and Infectious Diseases, (ii) Lung, Liver and Kidney Diseases, and (iii) Development of Cancer. Each chapter has discussed comprehensive knowledge regarding the molecular and cellular aspects of the role of RAS in the pathophysiology and pharmacotherapy of different disease processes. Biochemical mechanisms associated with angiotensin II type 1 and type II receptors, and angiotensin (1-7) MAS receptors for the occurrence of both harmful and beneficial effects of prolonged activation of RAS in different diseases have been outlined. It is noteworthy to point out that different chapter in this book were prepared by recognized global expertise in the area of inflammation, oxidative stress and signal transduction pathways to highlight the role of RAS in different diseases. It is our sincere hope that this book will be of great interest to both biomedical investigators and health professionals as well as graduate students and postdoctoral fellows all over the world.

Handbook of Neurochemistry and Molecular Neurobiology

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Publisher : Springer Science & Business Media
ISBN 13 : 0387303472
Total Pages : 511 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Handbook of Neurochemistry and Molecular Neurobiology by : Maarten E.A. Reith

Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Maarten E.A. Reith and published by Springer Science & Business Media. This book was released on 2007-06-12 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1840 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1840 pages. Available in PDF, EPUB and Kindle. Book excerpt: