Directed Selectivity In Organic Synthesis

Download Directed Selectivity In Organic Synthesis full books in PDF, epub, and Kindle. Read online Directed Selectivity In Organic Synthesis ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Directed Selectivity in Organic Synthesis

Download Directed Selectivity in Organic Synthesis PDF Online Free

Author : Tanja Gaich
Publisher : John Wiley & Sons
ISBN 13 : 3527667296
Total Pages : 368 pages
Book Rating : 4.5/5 (276 download)

Book Synopsis Directed Selectivity in Organic Synthesis by : Tanja Gaich

Download or read book Directed Selectivity in Organic Synthesis written by Tanja Gaich and published by John Wiley & Sons. This book was released on 2014-01-21 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together examples that until now were often hidden and widely spread throughout the original literature, this textbook shows how to use the correct reagents, conditions or reaction sequences to have access to all possible stereoisomers when beginning synthesis with only a single starting material. Adopting a didactic approach, the authors have chosen general and simple examples throughout the book so that these reactions can be transferred easily to other reaction types. While of major interest to master and PhD students alike, this book is also a source of valuable information for organic chemists in both academia and industry. Additional material for lectures at www.wiley-vch.de/textbooks

Selectivity in Organic Synthesis

Download Selectivity in Organic Synthesis PDF Online Free

Author : Robert S. Ward
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.3/5 (91 download)

Book Synopsis Selectivity in Organic Synthesis by : Robert S. Ward

Download or read book Selectivity in Organic Synthesis written by Robert S. Ward and published by John Wiley & Sons. This book was released on 1999-05-04 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selectivity is an important part of organic synthesis. The whole basis of organic chemistry, and especially organic synthesis, depends upon the selectivity which can be achieved in organic reactions. This concise textbook describes the strategies which can be adopted to improve selectivity, and the reactions which have been specially designed to afford high selectivity. The book illustrates the range of processes to which these principles can be applied and the high degree of selectivity which can be achieved. Selectivity in Organic Synthesis provides a solid introduction to this subject, focusing on the key areas and applications. Selectivity in Organic Synthesis features: * A concise introduction to selectivity in organic chemistry. * Lucidly written text including many carefully chosen examples and applications. * Numerous problems along with their solutions to help and encourage the reader. Suitable for organic chemistry students taking a course on organic synthesis or asymmetric synthesis in the 3rd or final year of an undergraduate chemistry course or in the first year of a postgraduate course.

Directed Evolution of Selective Enzymes

Download Directed Evolution of Selective Enzymes PDF Online Free

Author : Manfred T. Reetz
Publisher : John Wiley & Sons
ISBN 13 : 3527316604
Total Pages : 320 pages
Book Rating : 4.5/5 (273 download)

Book Synopsis Directed Evolution of Selective Enzymes by : Manfred T. Reetz

Download or read book Directed Evolution of Selective Enzymes written by Manfred T. Reetz and published by John Wiley & Sons. This book was released on 2016-12-19 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by one of the world's leading organic chemists, this authoritative reference provides an overview of basic strategies in directed evolution and introduces common gene mutagenesis, screening and selection methods. Throughout the text, emphasis is placed on methodology development to maximize efficiency, reliability and speed of the experiments and to provide guidelines for efficient protein engineering. Professor Reetz highlights the application of directed evolution experiments to address limitations in the field of enzyme selectivity, substrate scope, activity and robustness. He critically reviews recent developments and case studies, takes a look at future applications in the field of organic synthesis, and concludes with lessons learned from previous experiments.

Asymmetric Organic Synthesis with Enzymes

Download Asymmetric Organic Synthesis with Enzymes PDF Online Free

Author : Vicente Gotor
Publisher : John Wiley & Sons
ISBN 13 : 9783527318254
Total Pages : 348 pages
Book Rating : 4.3/5 (182 download)

Book Synopsis Asymmetric Organic Synthesis with Enzymes by : Vicente Gotor

Download or read book Asymmetric Organic Synthesis with Enzymes written by Vicente Gotor and published by John Wiley & Sons. This book was released on 2008-03-31 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perfect for biochemists, synthetic and organic chemists, this book covers all important reactions, including C-C coupling reactions, oxidation reactions and many more. Divided into two parts, the first section on methodology presents new innovative methods for enzymatic catalysis optimization, including such new trends as medium engineering, directed evolution and computer-aided prediction of enantioselectivity. The second and main section deals with applications to synthesis, showing important reaction types and their applications. Only those reactions with very high selectivity are presented, allowing readers to improve their own reaction yields.

Metal Promoted Selectivity in Organic Synthesis

Download Metal Promoted Selectivity in Organic Synthesis PDF Online Free

Author : A. Noels
Publisher : Springer Science & Business Media
ISBN 13 : 9401134081
Total Pages : 375 pages
Book Rating : 4.4/5 (11 download)

Book Synopsis Metal Promoted Selectivity in Organic Synthesis by : A. Noels

Download or read book Metal Promoted Selectivity in Organic Synthesis written by A. Noels and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: The demand for selective organic reactions is growing more acute everyday. Indeed, greater product selectivity has an important impact on energy and resource utilization, in terms of reduced process energy requirements for product separation and purification, in terms of low-value by-products, and in terms of environmental acceptance and compatibility. Moreover, more and more chemicals, especially pharmaceuticals, have to be sold in an optically active form. The search for selectivity constitutes a tremendous challenge for the chemists. In the last two decades, homogeneous transition metal based catalysis has emerged as one of the most promising tools for obtaining selectivity. In connection with developments in this area, this book contains updated and expanded versions of most of the lectures presented at a Cornett course held in Trieste (Italy) in 1989 and sponsored by the European Community. A primary aim is to cultivate a deeper understanding of the parameters that govern the selectivities and stimulate a wider utilization of transition metal based catalysis in organic synthesis. All aspects of selectivity, chemo-, regio-, stereo- and enantioselectivity are considered and illustrated by applications in various fields or organic synthesis. The impact of catalysis in oxydation, reduction, carbonylation reactions, carbene chemistry, in Ni and Pd promoted dimerizations, oligomerizations as well as fonctionalisations is stressed, quite often with special emphasis laid on reaction mechanisms. In this aspect, the last chapter examplifies the interest of high pressure NMR and IR when investigating the nature of reaction intermediates in homogeneous reactions.

Templated Organic Synthesis

Download Templated Organic Synthesis PDF Online Free

Author : François Diederich
Publisher : John Wiley & Sons
ISBN 13 : 3527613536
Total Pages : 431 pages
Book Rating : 4.5/5 (276 download)

Book Synopsis Templated Organic Synthesis by : François Diederich

Download or read book Templated Organic Synthesis written by François Diederich and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Template-controlled reactions allow the synthesis of complex molecules which would hardly be achievable through classical methods. This handbook offers authoratative information on how noncovalent and covalent templates can be effectively applied to control reaction rates as well as regio- and stereoselectivity. From the concepts of template control such as molecular imprinting, self-replication, and reversible tether-directed remote functionalization, the reader is led to template-based ring-closing reactions, oligomerizations, and multiple functionalizations and their application in the synthesis of supramolecular scaffolds and natural products. The editors and authors (J. F. Stoddart, G. Wulf, D. Lynn, R. Breslow. F. Diederich, just to name a few ) , all internationally recognized experts in their area, succeeded in presenting the manifold aspects of template-controlled synthesis in a didactic way, making this methodology accessible to a broad readership of organic synthetic chemists. Well-selected, reliable key experimental protocols and an up-to-date reference list underline the practical approach of this valuable handbook. Being the first book of its kind, it will serve as a pacemaker and stimulate future research.

Reduction

Download Reduction PDF Online Free

Author : Barry M. Trost
Publisher : Elsevier
ISBN 13 : 0080912516
Total Pages : 1166 pages
Book Rating : 4.0/5 (89 download)

Book Synopsis Reduction by : Barry M. Trost

Download or read book Reduction written by Barry M. Trost and published by Elsevier. This book was released on 1992-09-08 with total page 1166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains 37 chapters on methods for reducing functional groups, organized into four main parts. (i) Reduction of C=X systems, where X is an electronegative heteroatom, divided into 14 chapters based on the degree of reduction, the oxidation level of the C=X substrate, and on the nature of the reagent. (ii) Reduction of X=Y systems, divided into three chapters, covering the reduction of such groups as nitro, azo, and the various kinds of P=O and S=O groups. (iii) Reduction of C=C and C≡C, divided into 12 chapters based on the method of reduction, with aromatic, heteroaromatic, and conjugated systems treated separately, and including an extensive discussion of hydrometallation. (iv) Reduction of single bonds, C-X to C-H, in eight chapters, including the hydrogenolysis of the various kinds of C-X bonds, the reduction of epoxides, and the reduction of vinyl derivatives to alkenes. Each chapter includes a discussion of chemoselectivity, regioselectivity, and stereoselectivity, wherever it is appropriate, and most include advice on the reagent of choice, and the mechanistic basis of the various methods of reduction. In short, it is, within the space available, as near to a comprehensive account of reduction in organic chemistry as one could hope for.

Comprehensive Organic Synthesis: Additions to and substitutions at C-C[pi]-Bonds

Download Comprehensive Organic Synthesis: Additions to and substitutions at C-C[pi]-Bonds PDF Online Free

Author : Barry M. Trost
Publisher : Elsevier
ISBN 13 : 9780080405957
Total Pages : 1328 pages
Book Rating : 4.4/5 (59 download)

Book Synopsis Comprehensive Organic Synthesis: Additions to and substitutions at C-C[pi]-Bonds by : Barry M. Trost

Download or read book Comprehensive Organic Synthesis: Additions to and substitutions at C-C[pi]-Bonds written by Barry M. Trost and published by Elsevier. This book was released on 1991 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 4 focuses on additions and the resulting substitutions at carbon-carbon &pgr;-bonds. Part 1 includes processes generally considered as simple polar reactions, reactive electrophiles and nucleophiles adding to alkenes and alkynes. A major topic is Michael-type addition to electron deficient &pgr;-bonds, featured in the first six chapters. In part 2 are collected the four general processes leading to nucleophilic aromatic substitution, including radical chain processes and transition metal activation through to &pgr;-complexation. Metal-activated addition (generally by nucleophiles) to alkenes and polyenes is presented in part 3, including allylic alkylation catalyzed by palladium. The coverage of nonpolar additions in part 4 includes radical additions, organometal addition (Heck reaction), carbene addition, and 1,3-dipolar cycloadditions.

Remote C-H Bond Functionalizations

Download Remote C-H Bond Functionalizations PDF Online Free

Author : Debabrata Maiti
Publisher : John Wiley & Sons
ISBN 13 : 3527346678
Total Pages : 450 pages
Book Rating : 4.5/5 (273 download)

Book Synopsis Remote C-H Bond Functionalizations by : Debabrata Maiti

Download or read book Remote C-H Bond Functionalizations written by Debabrata Maiti and published by John Wiley & Sons. This book was released on 2021-04-26 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to contemporary advancements in the field of distal C-H functionalizations An important and dynamic topic within the modern field of organic synthesis, selective functionalization of C-H bonds can be used in a variety of applications across the pharmaceutical and agrochemical industries. Remote C-H Bond Functionalizations presents an inclusive account of the most recent developments and potential applications of performing variegated functionalizations selectively at the distal positions of organic compounds. Featuring contributions by an international team of experts, this authoritative volume provides deep insight into distal functionalizations, including detailed discussion of mechanisms, the engineering of templates, and the design of strategies. The text covers a diverse range of topics including C-H functionalization of palladium/norbornene catalysis, ruthenium-catalyzed remote functionalization, the non-directed distal C(sp2)-H, functionalization, transition metal catalyzed distal para-selective C-H functionalization, and much more. Reviewing contemporary advancements in the field while laying the foundation for future research, this important resource: Provides the most recent research and thorough coverage of the subject available in a single volume Offers practical information on C-H functionalizations in various industries Includes an up-to-date introduction to distal C-H functionalizations Remote C-H Bond Functionalizations is a must-read for every synthetic chemist, including chemists working with organometallics, organic chemists and researchers, and industrial chemists.

Oxidation

Download Oxidation PDF Online Free

Author : Barry M. Trost
Publisher : Elsevier
ISBN 13 : 0080912508
Total Pages : 1039 pages
Book Rating : 4.0/5 (89 download)

Book Synopsis Oxidation by : Barry M. Trost

Download or read book Oxidation written by Barry M. Trost and published by Elsevier. This book was released on 1992-09-08 with total page 1039 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers all methods of oxidation for use in organic synthesis. Emphasis has been placed on selectivity and functional group compatibility together with practical utility and applications. The volume is broadly divided to cover oxidation of unactivated carbon-hydrogen bonds, oxidation of activated carbon-hydrogen bonds, that is to say those adjacent to activating substituents and adjacent to heteroatoms, and oxidation of carbon-carbon double bonds. The volume also covers oxidation of C-X bonds, carbon-carbon single bonds, heteroatom oxidation and a number of special topics such as electrochemical methods, oxidative rearrangements, solid supported reagents, electron transfer oxidation, and biological methods.

Comprehensive Organic Synthesis

Download Comprehensive Organic Synthesis PDF Online Free

Author : Barry M. Trost
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (634 download)

Book Synopsis Comprehensive Organic Synthesis by : Barry M. Trost

Download or read book Comprehensive Organic Synthesis written by Barry M. Trost and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Enzyme Engineering

Download Enzyme Engineering PDF Online Free

Author : Manfred T. Reetz
Publisher : John Wiley & Sons
ISBN 13 : 3527350330
Total Pages : 405 pages
Book Rating : 4.5/5 (273 download)

Book Synopsis Enzyme Engineering by : Manfred T. Reetz

Download or read book Enzyme Engineering written by Manfred T. Reetz and published by John Wiley & Sons. This book was released on 2023-01-10 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzyme Engineering An authoritative and up-to-date discussion of enzyme engineering and its applications In Enzyme Engineering: Selective Catalysts for Applications in Biotechnology, Organic Chemistry, and Life Science, a team of distinguished researchers deliver a robust treatment of enzyme engineering and its applications in various fields such as biotechnology, life science, and synthesis. The book begins with an introduction to different protein engineering techniques, covers topics like gene mutagenesis methods for directed evolution and rational enzyme design. It includes industrial case studies of enzyme engineering with a focus on selectivity and activity. The authors also discuss new and innovative areas in the field, involving machine learning and artificial intelligence. It offers several insightful perspectives on the future of this work. Readers will also find: A thorough introduction to directed evolution and rational design as protein engineering techniques Comprehensive explorations of screening and selection techniques, gene mutagenesis methods in directed evolution, and guidelines for applying gene mutagenesis in organic chemistry, pharmaceutical applications, and biotechnology Practical discussions of protein engineering of enzyme robustness relevant to organic and pharmaceutical chemistry Treatments of artificial enzymes as promiscuous catalysts Various lessons learned from semi-rational and rational directed evolution A transdisciplinary treatise, Enzyme Engineering: Selective Catalysts for Applications in Biotechnology, Organic Chemistry, and Life Science is perfect for protein engineers, theoreticians, organic, and pharmaceutical chemists as well as transition metal researchers in catalysis and biotechnologists.

Comprehensive Organic Synthesis

Download Comprehensive Organic Synthesis PDF Online Free

Author :
Publisher :
ISBN 13 : 9780080359298
Total Pages : 21 pages
Book Rating : 4.3/5 (592 download)

Book Synopsis Comprehensive Organic Synthesis by :

Download or read book Comprehensive Organic Synthesis written by and published by . This book was released on 1991 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Side Reactions in Organic Synthesis II

Download Side Reactions in Organic Synthesis II PDF Online Free

Author : Florencio Zaragoza Dörwald
Publisher : John Wiley & Sons
ISBN 13 : 3527681728
Total Pages : 417 pages
Book Rating : 4.5/5 (276 download)

Book Synopsis Side Reactions in Organic Synthesis II by : Florencio Zaragoza Dörwald

Download or read book Side Reactions in Organic Synthesis II written by Florencio Zaragoza Dörwald and published by John Wiley & Sons. This book was released on 2014-06-23 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new textbook is the successor to the volume "Side Reactions in Organic Synthesis - A Guide to Successful Synthesis Design" (2004), written by the same author. Whereas the predecessor mainly covered the limitations of aliphatic substitution reactions, this new volume focuses on the most important aromatic substitution reactions, both electrophilic and nucleophilic, such as amination reactions, halogenation reactions, Friedel-Crafts acylations, or transition metal-catalyzed arylation reactions. Each chapter not only describes the scope of a specific reaction type, but also reveals what cannot be achieved with this reaction, i.e. what type of side reactions are to be expected with certain starting materials or electrophiles/nucleophiles. With its unique approach, this is a must-have book for graduate students in organic chemistry and synthetic chemists both in academia and industry!

Organic Synthesis Highlights V

Download Organic Synthesis Highlights V PDF Online Free

Author : Hans-Günther Schmalz
Publisher : John Wiley & Sons
ISBN 13 : 3527620494
Total Pages : 452 pages
Book Rating : 4.5/5 (276 download)

Book Synopsis Organic Synthesis Highlights V by : Hans-Günther Schmalz

Download or read book Organic Synthesis Highlights V written by Hans-Günther Schmalz and published by John Wiley & Sons. This book was released on 2008-09-26 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here, H.-G. Schmalz and T. Wirth have put together a collection of current contributions on the most important topics in organic chemistry all in one handy book. Like its successful predecessors, this volume provides readers with numerous articles on the current state of synthetic methods and their applications. The wide range covered by nearly forty contributions ensures a concise overview of the latest developments in the field, whether they be new methods of C-C bond formation or racemization, asymmetric phase-transfer catalysis or stereoselective metathesis reactions, solid phase reactions or particularly elegant syntheses of challenging natural products. Throughout, the highly renowned authors guarantee the exceptionally high quality of the articles, making this an indispensable read for everyone wanting to stay abreast of developments in organic chemistry.

Directed Metallation

Download Directed Metallation PDF Online Free

Author : Naoto Chatani
Publisher : Springer
ISBN 13 : 3540758097
Total Pages : 206 pages
Book Rating : 4.5/5 (47 download)

Book Synopsis Directed Metallation by : Naoto Chatani

Download or read book Directed Metallation written by Naoto Chatani and published by Springer. This book was released on 2007-10-03 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the broad scientific readership with a comprehensive summary and critical overview of a topic in organometallic chemistry. A wide variety of catalytic functionalization reactions of C-H bonds by the utilization of a chelation have been developed recently and are comprehensively discussed in this book by leading experts. In addition, new approaches to directed hydrometalation and directed carbometalation as a key step are also discussed.

Organolithiums

Download Organolithiums PDF Online Free

Author : Jonathan Clayden
Publisher : Elsevier
ISBN 13 : 9780080432625
Total Pages : 408 pages
Book Rating : 4.4/5 (326 download)

Book Synopsis Organolithiums by : Jonathan Clayden

Download or read book Organolithiums written by Jonathan Clayden and published by Elsevier. This book was released on 2002-07-12 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organolithiums: Selectivity for Synthesis.