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Efficiency In Natural Product Total Synthesis
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Book Synopsis Efficiency in Natural Product Total Synthesis by : Pei-Qiang Huang
Download or read book Efficiency in Natural Product Total Synthesis written by Pei-Qiang Huang and published by John Wiley & Sons. This book was released on 2018-07-24 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis • Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section • Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals
Book Synopsis Efficiency in Natural Product Total Synthesis by : Pei-Qiang Huang
Download or read book Efficiency in Natural Product Total Synthesis written by Pei-Qiang Huang and published by John Wiley & Sons. This book was released on 2018-10-16 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis • Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section • Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals
Book Synopsis Total Synthesis of Natural Products by : Jie Jack Li
Download or read book Total Synthesis of Natural Products written by Jie Jack Li and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.
Book Synopsis From Biosynthesis to Total Synthesis by : Alexandros L. Zografos
Download or read book From Biosynthesis to Total Synthesis written by Alexandros L. Zografos and published by John Wiley & Sons. This book was released on 2016-04-18 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on biosynthesis, this book provides readers with approaches and methodologies for modern organic synthesis. By discussing major biosynthetic pathways and their chemical reactions, transformations, and natural products applications; it links biosynthetic mechanisms and more efficient total synthesis. • Describes four major biosynthetic pathways (acetate, mevalonate, shikimic acid, and mixed pathways and alkaloids) and their related mechanisms • Covers reactions, tactics, and strategies for chemical transformations, linking biosynthetic processes and total synthesis • Includes strategies for optimal synthetic plans and introduces a modern molecular approach to natural product synthesis and applications • Acts as a key reference for industry and academic readers looking to advance knowledge in classical total synthesis, organic synthesis, and future directions in the field
Book Synopsis The Total Synthesis of Natural Products, Volume 7 by : John ApSimon
Download or read book The Total Synthesis of Natural Products, Volume 7 written by John ApSimon and published by John Wiley & Sons. This book was released on 2009-09-22 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: The appearance of the seventh volume of The Total Synthesis of Natural Products signals the continued health of the art and science of organic synthesis. This new volume contains a chapter updating monoterpene synthesis and reviews the newer areas of leukotrienes and macro-cyclic lactones. The Total Synthesis of Natural Products, Volume Seven forms an integral part of the invaluable working reference begun in Volumes One through Six, to which chemists may turn for the available data on the total synthesis of complex molecules. Lessons learned from the synthetic challenges presented here by various natural products will serve as a sound base for this continually evolving field.
Book Synopsis Total Synthesis of Natural Products, the "Chiron" Approach by : Stephen Hanessian
Download or read book Total Synthesis of Natural Products, the "Chiron" Approach written by Stephen Hanessian and published by Pergamon. This book was released on 1983 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Protecting-Group-Free Organic Synthesis by : Rodney A. Fernandes
Download or read book Protecting-Group-Free Organic Synthesis written by Rodney A. Fernandes and published by John Wiley & Sons. This book was released on 2018-08-20 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a comprehensive account of established protecting-group-free synthetic routes to molecules of medium to high complexity This book supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and back the global need of practicing green chemistry. The only resource of its kind to focus entirely on protecting-group-free synthesis, it is edited by a leading practitioner in the field, and features enlightening contributions by top experts and researchers from across the globe. The introductory chapter includes a concise review of historical developments, and discusses the concepts, need for, and future prospects of protecting-group-free synthesis. Following this, the book presents information on protecting-group-free synthesis of complex natural products and analogues, heterocycles, drugs, and related pharmaceuticals. Later chapters discuss practicing protecting-group-free synthesis using carbohydrates and of glycosyl derivatives, glycol-polymers and glyco-conjugates. The book concludes with a chapter on latent functionality as a tactic toward formal protecting-group-free synthesis. A comprehensive account of established protecting-group-free (PGF) synthetic routes to molecules of medium to high complexity Benefits total synthesis, methodology development and drug synthesis researchers Supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and support the global need of practicing green chemistry Covers a topic that is gaining importance because it renders syntheses more economical Protecting-Group-Free Organic Synthesis: Improving Economy and Efficiency is an important book for academic researchers in synthetic organic chemistry, green chemistry, medicinal and pharmaceutical chemistry, biochemistry, and drug discovery.
Book Synopsis Chemical and Biological Synthesis by : Nick J Westwood
Download or read book Chemical and Biological Synthesis written by Nick J Westwood and published by Royal Society of Chemistry. This book was released on 2018-08-16 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic chemistry plays a central role in many areas of chemical biology; utilising recent case studies, the goal of Chemical and Biological Synthesis is to highlight the full impact that the preparation of novel reagents can have in chemical biology. Covering the synthetic approaches that can be applied across the whole field of chemical biology, this book provides synthetic chemists with the broader context to which their work contributes and the biological questions that can be addressed through it. An ideal guide for postgraduate students and researchers in synthetic organic chemistry and chemical biology, Chemical and Biological Synthesis introduces synthetic techniques and methods to those who wish to incorporate synthesis for the first time in their biology-focused research programmes.
Book Synopsis The Total Synthesis of Natural Products by : John ApSimon
Download or read book The Total Synthesis of Natural Products written by John ApSimon and published by . This book was released on 1973 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Classics in Total Synthesis by : K. C. Nicolaou
Download or read book Classics in Total Synthesis written by K. C. Nicolaou and published by John Wiley & Sons. This book was released on 1996-04-11 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: K.C. Nicolaou - Winner of the Nemitsas Prize 2014 in Chemistry This book is a must for every synthetic chemist. With didactic skill and clarity, K. C. Nicolaou and E. Sorensen present the most remarkable and ingenious total syntheses from outstanding synthetic organic chemists. To make the complex strategies more accessible, especially to the novice, each total synthesis is analyzed retrosynthetically. The authors then carefully explain each synthetic step and give hints on alternative methods and potential pitfalls. Numerous references to useful reviews and the original literature make this book an indispensable source of further information. Special emphasis is placed on the skillful use of graphics and schemes: Retrosynthetic analyses, reaction sequences, and stereochemically crucial steps are presented in boxed sections within the text. For easy reference, key intermediates are also shown in the margins. Graduate students and researchers alike will find this book a gold mine of useful information essential for their daily work. Every synthetic organic chemist will want to have a copy on his or her desk.
Book Synopsis The logic of chemical synthesis by : E.J. Corey
Download or read book The logic of chemical synthesis written by E.J. Corey and published by Рипол Классик. This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Medicinal Natural Products by : Paul M. Dewick
Download or read book Medicinal Natural Products written by Paul M. Dewick and published by John Wiley & Sons. This book was released on 2002-01-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.
Book Synopsis Retrosynthetic Analysis and Synthesis of Natural Products 1 by : Olivier Piva
Download or read book Retrosynthetic Analysis and Synthesis of Natural Products 1 written by Olivier Piva and published by John Wiley & Sons. This book was released on 2019-09-24 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: For chemists, attempting to mimic nature by synthesizing complex natural products from raw material is a challenge that is fraught with pitfalls. To tackle this unique but potentially rewarding task, researchers can rely on well-established reactions and methods of practice, or apply their own synthesis methods to verify their potential. Whatever the goal and its complexity, there are multiple ways of achieving it. We must now establish a strategic and effective plan that requires the minimum number of steps, but lends itself to widespread use. This book is structured around the study of a dozen target products (butyrolactone, macrolide, indole compound, cyclobutanic terpene, spiro- and polycyclic derivatives, etc.). For each product, the different disconnections are presented and the associated syntheses are analyzed step by step. The key reactions are described explicitly, followed by diagrams showing the range of impact of certain transformations. This set of data alone is conducive to understanding syntheses and indulging in this difficult, but worthwhile activity.
Book Synopsis The Total Synthesis of Natural Products, Volume 1 by : John ApSimon
Download or read book The Total Synthesis of Natural Products, Volume 1 written by John ApSimon and published by Wiley-Interscience. This book was released on 1973-04-20 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vocabulary of Organic Chemistry Milton Orchin, Fred Kaplan, Roger S. Macomber, R. Marshall Wilson & Hans W. Zimmer Identifies those terms and concepts which now constitute the vocabulary of organic chemists, then defines and explains these terms and concepts, most often using examples. Organized so that subject matter builds successively on increasingly varied and complex material. All terms and concepts related to a particular area are placed together, except for one chapter on name and type reactions, which is alphabetically arranged. The only book of its kind valuable to students, teachers and chemical professionals alike. 1980 Protective Groups in Organic Synthesis Theodora W. Greene Provides essential information on transformations of organic molecules, including instructions and references for the protection and regeneration of the major organic functional groups: -OH, -NH, -SH, -COOH, and C = O. Covers the best methods of formation and cleavage, properties of protective groups, selection of a group for a particular need. Organization is by functional groups to be protected, with groups arranged in order of increasing complexity of structure, and with most efficient methods of formation or cleavage described first. Charts show the reactivities of 270 of the most commonly used protective groups to 108 reagents, selected as prototypes for the entire array of reagents available to the organic chemist. 1981 Basics of Electroorganic Synthesis Demetrios K. Kyriacou A veteran organic electrochemist illuminates fundamental ideas and principles by means of selected examples from the literature and his own research, demonstrating the practical unity of the field in a clear, concise manner. Describes the general electroorganic reaction and illustrates the general mode of concepts and applications in the area of electrosynthesis. Contains a brief survey of electroorganic reactions and coverage of special topics and the praxis of electroorganic synthesis. 1981
Book Synopsis Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules by : Yuichi Kobayashi
Download or read book Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules written by Yuichi Kobayashi and published by Springer. This book was released on 2020-08-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes cutting-edge organic syntheses of biologically active compounds, isolation of pharmaceutically promising compounds from microorganisms, drug design, and progress on chemical biology. Synthetic strategy and tactics are summarized for super-carbon chain compounds, antitumor polycycles, aryl C-glycoside, antimycins, duocarmycins, cannabinoids, and other compounds. Special chapters are devoted to synthesis and biochemistry of fatty acid metabolites, which play a central role in the initiation and resolution of inflammation. The book provides a quick survey of trending topics in organic synthesis and chemical tools for biological investigation, and furnishes ideas for future research in organic synthesis. In addition, the contents can easily be understood by young chemists, graduate students, and those who are looking for new research based on organic chemistry.
Book Synopsis Strategic Applications of Named Reactions in Organic Synthesis by : Laszlo Kurti
Download or read book Strategic Applications of Named Reactions in Organic Synthesis written by Laszlo Kurti and published by Elsevier. This book was released on 2005-04-29 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. * The first reference work on named reactions to present colored schemes for easier understanding * 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples * An opening list of abbreviations includes both structures and chemical names * Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works * Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools * Extensive index quickly locates information using words found in text and drawings
Book Synopsis Drug Discovery and Design Using Natural Products by : Jorddy Neves Cruz
Download or read book Drug Discovery and Design Using Natural Products written by Jorddy Neves Cruz and published by Springer Nature. This book was released on 2023-08-28 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historically, natural products have great relevance for the development of new drugs. Natural molecules, in addition to directly providing new compounds with different therapeutic functions have provided scaffolds and a great diversity of structures that serve as inspiration for the design and discovery of new drugs. The great structural complexity and the significant number of natural compounds that can be obtained and their advantages also present some historical problems that need to be overcome. Issues such as difficulty in isolation, difficulty in synthesizing compounds found in nature in the laboratory, screening to evaluate the biological properties of these compounds, and structural optimization to enhance the pharmacological properties of biomolecules; are some of the main difficulties encountered in research with natural products and in the design/discovery of new medicines. Therefore, this book addresses the great scientific advances that provide practical solutions to using natural products to develop new drugs. We address topics related to the genesis of research projects that use natural products to design new drugs. We address the discovery of new species, initial processes for identification and extraction of compounds, isolation and identification of these structures, techniques, and advances in vitro and in vivo methods that support the discovery of new natural drugs, synthesis of new compounds from natural molecules, in silico optimization processes of potentially promising compounds.
