Chemical And Biological Synthesis

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Chemical and Biological Synthesis

Author : Nick J Westwood
Publisher : Royal Society of Chemistry
ISBN 13 : 178801507X
Total Pages : 339 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Chemical and Biological Synthesis by : Nick J Westwood

Download or read book Chemical and Biological Synthesis written by Nick J Westwood and published by Royal Society of Chemistry. This book was released on 2018-08-16 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic chemistry plays a central role in many areas of chemical biology; utilising recent case studies, the goal of Chemical and Biological Synthesis is to highlight the full impact that the preparation of novel reagents can have in chemical biology. Covering the synthetic approaches that can be applied across the whole field of chemical biology, this book provides synthetic chemists with the broader context to which their work contributes and the biological questions that can be addressed through it. An ideal guide for postgraduate students and researchers in synthetic organic chemistry and chemical biology, Chemical and Biological Synthesis introduces synthetic techniques and methods to those who wish to incorporate synthesis for the first time in their biology-focused research programmes.

Asymmetric Synthesis with Chemical and Biological Methods

Author : Dieter Enders
Publisher : John Wiley & Sons
ISBN 13 : 3527610634
Total Pages : 470 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Asymmetric Synthesis with Chemical and Biological Methods by : Dieter Enders

Download or read book Asymmetric Synthesis with Chemical and Biological Methods written by Dieter Enders and published by John Wiley & Sons. This book was released on 2007-06-27 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by two of the leading researchers in the field, this book provides a deep, interdisciplinary insight into stoichiometric and catalytic reactions in this continuously expanding area. A plethora of top German scientists with an international reputation covers various aspects, from classical organic chemistry to process development, and from the theoretical background to biological methods using enzymes. Throughout the focus is on the development of new synthetic methods in asymmetric synthesis, the synthesis of natural and bioactive compounds and the latest developments in both chemical and biological methods of catalysis, as well as the investigation of special technical and biotechnical aspects.

Diversity-Oriented Synthesis

Author : Andrea Trabocchi
Publisher : John Wiley & Sons
ISBN 13 : 1118618149
Total Pages : 550 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Diversity-Oriented Synthesis by : Andrea Trabocchi

Download or read book Diversity-Oriented Synthesis written by Andrea Trabocchi and published by John Wiley & Sons. This book was released on 2013-06-17 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover an enhanced synthetic approach to developing and screening chemical compound libraries Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology. Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book: Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles Expands on the concept of diversity-oriented synthesis by describing chemical libraries Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications. Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

Organoselenium Compounds in Biology and Medicine

Author : Vimal Kumar Jain
Publisher : Royal Society of Chemistry
ISBN 13 : 1788010299
Total Pages : 457 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Organoselenium Compounds in Biology and Medicine by : Vimal Kumar Jain

Download or read book Organoselenium Compounds in Biology and Medicine written by Vimal Kumar Jain and published by Royal Society of Chemistry. This book was released on 2017-10-03 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organoselenium shows incredible promise in medicine, particularly cancer therapy. This book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications. Divided into three sections, the first section describes synthetic advances in bioactive selenium compounds, revealing how organoselenium compound toxicity, redox properties and specificity can be further tuned. The second section explains the biophysics and biochemistry of organoselenium compounds, as well as selenoproteins. The final section closes with several chapters devoted to therapeutic and medicinal applications of organoselenium compounds, covering radioprotectors, anticancer agents and antioxidant behaviour. With contributions from leading global experts, this book covers recent advances in the field and is an ideal reference for those researching organoselenium compounds.

Chemical Approaches to the Synthesis of Peptides and Proteins

Author : Paul Lloyd-Williams
Publisher : CRC Press
ISBN 13 : 9780849391422
Total Pages : 306 pages
Book Rating : 4.3/5 (914 download)

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Book Synopsis Chemical Approaches to the Synthesis of Peptides and Proteins by : Paul Lloyd-Williams

Download or read book Chemical Approaches to the Synthesis of Peptides and Proteins written by Paul Lloyd-Williams and published by CRC Press. This book was released on 1997-04-23 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic chemists working on the synthesis of natural products have long found a special challenge in the preparation of peptides and proteins. However, more reliable, more efficient synthetic preparation methods have been developed in recent years. This reference evaluates the most important synthesis methods available today, and also considers methods that show promise for future applications. This text describes the state of the art in efficient synthetic methods for the synthesis of both natural and artificial large peptide and protein molecules. Subjects include an introduction to basic topics, linear solid-phase synthesis of peptides, peptide synthesis in solution, convergent solid-phase synthesis, methods for the synthesis of branched peptides, formation of disulfide bridges, and more. The book emphasizes strategies and tactics that must be considered for the successful synthesis of peptides.

Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules

Author : Yuichi Kobayashi
Publisher : Springer
ISBN 13 : 9789811362460
Total Pages : 0 pages
Book Rating : 4.3/5 (624 download)

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Book Synopsis Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules by : Yuichi Kobayashi

Download or read book Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules written by Yuichi Kobayashi and published by Springer. This book was released on 2020-08-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes cutting-edge organic syntheses of biologically active compounds, isolation of pharmaceutically promising compounds from microorganisms, drug design, and progress on chemical biology. Synthetic strategy and tactics are summarized for super-carbon chain compounds, antitumor polycycles, aryl C-glycoside, antimycins, duocarmycins, cannabinoids, and other compounds. Special chapters are devoted to synthesis and biochemistry of fatty acid metabolites, which play a central role in the initiation and resolution of inflammation. The book provides a quick survey of trending topics in organic synthesis and chemical tools for biological investigation, and furnishes ideas for future research in organic synthesis. In addition, the contents can easily be understood by young chemists, graduate students, and those who are looking for new research based on organic chemistry.

Beyond the Molecular Frontier

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309168392
Total Pages : 238 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Beyond the Molecular Frontier by : National Research Council

Download or read book Beyond the Molecular Frontier written by National Research Council and published by National Academies Press. This book was released on 2003-03-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.

Biological Synthesis of Nanoparticles and Their Applications

Author : L Karthik
Publisher : CRC Press
ISBN 13 : 0429555784
Total Pages : 299 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Biological Synthesis of Nanoparticles and Their Applications by : L Karthik

Download or read book Biological Synthesis of Nanoparticles and Their Applications written by L Karthik and published by CRC Press. This book was released on 2019-12-06 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Synthesis of Nanoparticles and Their Applications gives insight into the synthesis of nanoparticles utilizing the natural routes. It demonstrates various strategies for the synthesis of nanoparticles utilizing plants, microscopic organisms like bacteria, fungi, algae and so forth. It orchestrates interdisciplinary hypothesis, ideas, definitions, models and discoveries associated with complex cell of the prokaryotes and eukaryotes. Highlights: Discusses biological approach towards the nanoparticle synthesis Describes the role of nanotechnology in the field of medicine and its medical devices Covers application and usage of the chemicals at the molecular level to act as catalysts and binding products for both organic and inorganic Chemical Reactions Reviews application in physics such as solar cells, photovoltaics and other usage Microorganisms can aggregate and detoxify substantial metals because of different reductase enzymes, which can diminish metal salts to metal nanoparticles. The readers after going through this book will have detailed account of mechanism of bio-synthesis of nanoparticles.

Advanced Chemical Biology

Author : Howard C. Hang
Publisher : John Wiley & Sons
ISBN 13 : 3527826300
Total Pages : 806 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Advanced Chemical Biology by : Howard C. Hang

Download or read book Advanced Chemical Biology written by Howard C. Hang and published by John Wiley & Sons. This book was released on 2023-02-06 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Chemical Biology The modern approach to teaching chemical biology Advanced Chemical Biology is organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures, including core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis. Advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology, are covered in separate sections. Every chapter is homogeneous in style and layout, consisting of a short historical introduction followed by a description of the underlying concepts and a selection of recent examples of how the concept has been turned into practice. The subdivision of the contents into core and supplemental chapters enables a flexible use in teaching, both for a one-semester and a two-semester course. Written by authors and editors coming from the leading scientific institutions that have developed the concepts and technologies for this discipline, Advanced Chemical Biology includes specific information on topics like: DNA function, synthesis and engineering, chemical approaches to genome integrity, and RNA function, synthesis, and probing Chemical approaches to transcription and RNA regulation in vivo, chemical biology of genome engineering, and peptide/protein synthesis and engineering Directed evolution for chemical biology, chemical biology of cellular metabolism, chemical biology of lipids, and protein post-translational modifications Chemical glycobiology, chemical and enzymatic modification of proteins, genetic code expansion, bio-orthogonal chemistry, and cellular imaging With its broad scope and focus on turning concepts into applications, Advanced Chemical Biology is an excellent starting point for anyone entering the field and looking for a guide to the wide range of available methods and strategies that chemical biology has to offer. With a Foreword by Nobel Laureate Carolyn Bertozzi.

Industrialization of Biology

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309316553
Total Pages : 167 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Industrialization of Biology by : National Research Council

Download or read book Industrialization of Biology written by National Research Council and published by National Academies Press. This book was released on 2015-06-29 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.

Essentials of Chemical Biology

Author : Andrew D. Miller
Publisher : John Wiley & Sons
ISBN 13 : 1119437970
Total Pages : 564 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Essentials of Chemical Biology by : Andrew D. Miller

Download or read book Essentials of Chemical Biology written by Andrew D. Miller and published by John Wiley & Sons. This book was released on 2024-01-24 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Chemical Biology Discover a detailed knowledge of concepts and techniques that shape this unique multi-discipline Chemical Biology is devoted to understanding the way that Biology works at the molecular level. This is a problem-driven multi-discipline, incorporating as it does Organic, Physical, Inorganic, and Analytical Chemistry alongside newer emerging molecular disciplines. In recent years, Chemical Biology has emerged as a vibrant and growing multi-discipline distinct from Biochemistry that is focused on the quantitative analyses of the structures and functions of biological macromolecules and macromolecular lipid assemblies, at first in isolation, then in vitro and in vivo. The second edition of the Essentials of Chemical Biology begins with a thorough introduction to the structure of biological macromolecules and macromolecular lipid assemblies, before moving on to the principles of chemical and biological synthesis, followed by descriptions of a comprehensive variety of research techniques and experimental methods. In addition, the second edition now includes new sections on the behaviour of biological macromolecules and macromolecular lipid assemblies in cells in vitro and in organisms in vivo. Given this, the second edition of the Essentials of Chemical Biology promises to cement itself as the leading introduction to Chemical Biology, incorporating descriptions of cutting-edge research wherever appropriate. Hence, readers of the second edition of the Essentials of Chemical Biology will find: a general expansion in understanding of basic molecular mechanisms in Biology moving towards cellular and organismal mechanisms entirely new chapters covering miniaturization and array technologies, Chemical Cell Biology, and the interface between Chemical Biology and Nanotechnology updates to chapters reflecting recent research developments an increased engagement with medical applications Essentials of Chemical Biology is ideal for advanced undergraduates or (post) graduate students in Chemical Biology and adjacent fields.

Green Processes for Nanotechnology

Author : Vladimir A. Basiuk
Publisher : Springer
ISBN 13 : 3319154613
Total Pages : 446 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Green Processes for Nanotechnology by : Vladimir A. Basiuk

Download or read book Green Processes for Nanotechnology written by Vladimir A. Basiuk and published by Springer. This book was released on 2015-03-25 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the state-of-the-art survey of green techniques in preparation of different classes of nanomaterials, with an emphasis on the use of renewable sources. Key topics covered include fabrication of nanomaterials using green techniques as well as their properties and applications, the use of renewable sources to obtain nanomaterials of different classes, from simple metal and metal oxide nanoparticles to complex bioinspired nanomaterials, economic contributions of nanotechnology to green and sustainable growth, and more. This is an ideal book for students, lecturers, researchers and engineers dealing with versatile (mainly chemical, biological, and medical) aspects of nanotechnology, including fabrication of nanomaterials using green techniques and their properties and applications.

Cyclic Peptides

Author : Jesko Koehnke
Publisher : Royal Society of Chemistry
ISBN 13 : 1782625283
Total Pages : 392 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Cyclic Peptides by : Jesko Koehnke

Download or read book Cyclic Peptides written by Jesko Koehnke and published by Royal Society of Chemistry. This book was released on 2017-12-15 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to utility in biology and drug discovery.

Biomimetic Organic Synthesis

Author : Erwan Poupon
Publisher : John Wiley & Sons
ISBN 13 : 3527634762
Total Pages : 1024 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Biomimetic Organic Synthesis by : Erwan Poupon

Download or read book Biomimetic Organic Synthesis written by Erwan Poupon and published by John Wiley & Sons. This book was released on 2011-05-09 with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this exciting 2 volume set, the approach and methodology of bio-inspired synthesis of complex natural products is laid out, backed by abundant practical examples from the authors' own work as well as from the published literature. Volume 1 describes the biomimetic synthesis of alkaloids. Volume 2 covers terpenes, polyketides, and polyphenols. A discussion of the current challenges and frontiers in biomimetic synthesis concludes this comprehensive handbook. Key features: Biomimetic Strategies have become an every-day tool not only for chemists but also for biologists. The synthetic applications are overwhelming, making this comprehensive 2 volume work a must-have for everyone working in the field. Unifying both synthetic and biosynthetic aspects, this book covers everything from organocatalysis and natural product synthesis to synthetic biology and even green chemistry.

Total Synthesis of Natural Products

Author : Jie Jack Li
Publisher : Springer Science & Business Media
ISBN 13 : 3642340652
Total Pages : 292 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Total Synthesis of Natural Products by : Jie Jack Li

Download or read book Total Synthesis of Natural Products written by Jie Jack Li and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.

Efficiency in Natural Product Total Synthesis

Author : Pei-Qiang Huang
Publisher : John Wiley & Sons
ISBN 13 : 1118605403
Total Pages : 512 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Efficiency in Natural Product Total Synthesis by : Pei-Qiang Huang

Download or read book Efficiency in Natural Product Total Synthesis written by Pei-Qiang Huang and published by John Wiley & Sons. This book was released on 2018-10-16 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis • Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section • Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals

Chemical Ligation

Author : Luca D. D'Andrea
Publisher : John Wiley & Sons
ISBN 13 : 1119044103
Total Pages : 492 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Chemical Ligation by : Luca D. D'Andrea

Download or read book Chemical Ligation written by Luca D. D'Andrea and published by John Wiley & Sons. This book was released on 2017-04-03 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting a wide array of information on chemical ligation – one of the more powerful tools for protein and peptide synthesis – this book helps readers understand key methodologies and applications that protein therapeutic synthesis, drug discovery, and molecular imaging. • Moves from fundamental to applied aspects, so that novice readers can follow the entire book and apply these reactions in the lab • Presents a wide array of information on chemical ligation reactions, otherwise scattered across the literature, into one source • Features comprehensive and multidisciplinary coverage that goes from basics to advanced topics • Helps researchers choose the right chemical ligation technique for their needs