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Author : Stuart C. Apfel
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.3/5 (91 download)
Download or read book Clinical Applications of Neurotrophic Factors written by Stuart C. Apfel and published by Lippincott Williams & Wilkins. This book was released on 1997 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lawrence Kruger
Publisher : CRC Press
ISBN 13 : 1439812101
Total Pages : 432 pages
Book Rating : 4.4/5 (398 download)
Download or read book Translational Pain Research written by Lawrence Kruger and published by CRC Press. This book was released on 2009-11-24 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practicality of clinical trials, Translational Pain Research: From Mouse to Man effectively bridges the gap between basic research and patient care by humanely examining rodent models for pain associated with bone cancer, osteoarthritis, fibromyalgia, and cardiac episodes. Distinguished Team of International Contributors In addition to addressing the groundbreaking technical advances in tract tracing, endocannabinoids, cannabis, gene therapy, siRNA gene studies, and the role of glia, cytokines, P2X receptors and ATP, this book also presents cutting-edge information on: Nociceptor sensitization Muscle nociceptors and metabolite detection Visceral afferents in disease Innovative rodent model for bone cancer pain Highly specific receptor cloning Modular molecular mechanisms relevant to painful neuropathies This sharply focused work also discusses unexpected discoveries derived from brain-imaging studies related to thalamic pain. Translational Pain Research covers the progress made toward bringing laboratory science (much of it at the molecular level) to our understanding of pain phenomena in humans, with the ultimate goal of reducing the suffering that often accompanies pain and its indirect consequences.
Author : Kurt Jellinger
Publisher : Springer Science & Business Media
ISBN 13 : 9783211837979
Total Pages : 398 pages
Book Rating : 4.8/5 (379 download)
Download or read book Ageing and Dementia written by Kurt Jellinger and published by Springer Science & Business Media. This book was released on 2002-08-20 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiological studies, modern clinical, neuroimaging, neuropsychological, molecular biological, and genetic studies have considerably enhanced our knowledge about ageing processes of the human brain, its sequelae, diagnostic, and therapeutic possibilities and limits. In addition to Alzheimer's disease and other degenerative dementias, the impact of cerebrovascular lesions and their risk factors in the pathogenesis of cognitive disorders of the aged are increasingly acknowledged, and the recognition of mild cognitive impairment as a frequent initial stage of developing dementia is becoming an increasingly important diagnostic and therapeutic problem. The included papers were presented at the 7th International Symposium in Graz, Sept. 2001 and give a timely overview of the current and future concepts of pathogenesis, diagnosis, and treatment strategies of pathological brain ageing and dementias, early recognition of mild cognitive impairment and future possiblities of prevention of dementing processes.
Author : Gregory R. Bock
Publisher : John Wiley & Sons
ISBN 13 : 0470514876
Total Pages : 264 pages
Book Rating : 4.4/5 (75 download)
Download or read book Growth Factors as Drugs for Neurological and Sensory Disorders written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Degeneration of sensory receptors or of the nerves innervating them leads to a sensory deficit. Various strategies have been tried for promoting regrowth of sensory receptors, particularly in the eye and ear. The latest data from experimental studies in animals are presented in the book including applications of BDNF and CNTF in the eye and epidermal growth factor in the ear.
Author : John R. Wingard
Publisher : Springer Science & Business Media
ISBN 13 : 1461550130
Total Pages : 407 pages
Book Rating : 4.4/5 (615 download)
Download or read book Clinical Applications of Cytokines and Growth Factors written by John R. Wingard and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hematopoietic system plays roles that are crucial for survival of the host: delivery of oxygen to tissues, arrest of accidental blood leaking from blood vessels, and fending off of invading microbes by humoral, cell-mediated, and phagocytic immunity. The activity of the hematopoietic system is staggering: daily, a normal adult produces approximately 2.5 billion erythrocytes, 2.5 billion platelets, and 1 billion granulocytes per kilogram of body weight. This production is adjusted in a timely fashion to changes in actual needs and can vary from nearly none to many times the normal rate depending on needs which vary from day to day, or even minute to minute. In response to a variety of stimuli, the cellular components of the blood are promptly increased or decreased in production to maintain appropriate numbers to optimally protect the host from hypoxia, infection, and hemorrhage. How does this all happen and happen without over or under responding? There has been extraordinary growth in our understanding ofhematopoiesis over the last two decades. Occupying center stage is the pluripotent stern cell and its progeny. Hematopoietic stern cells have been characterized by their capacity for self renewal and their ability to proliferate and differentiate along multiple lineages. Few in number, the stern cell gives rise to all circulating neutrophils, erythrocytes, lymphoid cells, and platelets. In hematopoietic transplantation, the stern cell is capable of restoring long-term hematopoiesis in a lethally irradiated host.
Author : Hugo Lagercrantz
Publisher : Cambridge University Press
ISBN 13 : 0521889758
Total Pages : 427 pages
Book Rating : 4.5/5 (218 download)
Download or read book The Newborn Brain written by Hugo Lagercrantz and published by Cambridge University Press. This book was released on 2010-01-07 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this respected work presents a comprehensive review of basic mechanisms of fetal and neonatal brain development.
Author : Simons Michael
Publisher : World Scientific
ISBN 13 : 981314338X
Total Pages : 284 pages
Book Rating : 4.8/5 (131 download)
Download or read book Fibroblast Growth Factors: Biology And Clinical Application - Fgf Biology And Therapeutics written by Simons Michael and published by World Scientific. This book was released on 2016-12-27 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fibroblast growth factor (FGF) family of ligands and the corresponding family of FGF receptor tyrosine kinases comprise one of the most versatile and diverse growth factor signaling families in vertebrates, found virtually in every tissue and cell type where they regulate metabolic and physiologic function, maintain tissue homeostasis, and mediate injury response, tissue repair, and regeneration. As a result, FGFs play critical roles in a wide variety of normal biological and abnormalities in FGF signaling can lead to a variety of disease states from developmental malformations, to atherosclerosis, pulmonary hypertension and cancer among many others. A thorough understanding of this system is necessary for critical insights into both normal and disease biology and is essential to development of rationale therapeutic strategies aimed at treatment of FGF-dependent diseases states. Recent years have seen advances in our understanding of FGFs role in endothelial and, more general, vascular biology, the subject of this book. In particular, FGFs have been implicated in the maintenance of vascular homeostasis and control of blood vessel permeability while aberrant FGF signaling has been shown to be central to the development of pulmonary hypertension, and endothelial-to-mesenchymal transition, a process implicated in the development of atherosclerosis. Finally, FGFs ability to stimulate blood vessel growth has been explored in therapeutic angiogenesis approaches. With this in mind, the present monograph is structured to provide comprehensive information to a reader interested in FGFs in general and vascular biology in particular. To this end, we explore everything from the structure and signaling of FGFs and their receptors (Chapters 1, 2 and 3) to their role in the regulation of vascular homeostasis (Chapter 4) and cardiovascular diseases (Chapters 5 and 6). We then address new developments in FGF therapeutics (chapter 7) and explore FGF biology in the epithelium (Chapter 8) thereby providing a complete analysis of this growth factor family biology in two closely related but distinctly different environments — endothelium and epithelium. Finally, we examine FGF biology in eye disease and in cancer. It is our hope that this comprehensive treatment of FGF vascular biology and its application will provide the reader with the accurate and timely summary of this rapidly moving field.
Author : Napoleone Ferrara
Publisher : CRC Press
ISBN 13 : 1420004379
Total Pages : 280 pages
Book Rating : 4.4/5 (2 download)
Download or read book Angiogenesis written by Napoleone Ferrara and published by CRC Press. This book was released on 2006-08-15 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why a new book on angiogenesis and why now? For the first time concepts proposed over 30 years ago have found clinical validation. In the last two years the first antiangiogenic agents have been approved by the FDA for the treatment of cancer and age-related macular degeneration. Not surprisingly, this clinical success has raised a new set of basic
Author : Yusuf Tutar
Publisher : BoD – Books on Demand
ISBN 13 : 1789231124
Total Pages : 152 pages
Book Rating : 4.7/5 (892 download)
Download or read book Plasma Medicine written by Yusuf Tutar and published by BoD – Books on Demand. This book was released on 2018-05-16 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasma can be defined as the extracellular matrix of blood cells. Plasma components, their role in human health risk evaluation, and their functional and clinical analyses are covered in this book. Furthermore, physical plasma-ionized gas is one of the four fundamental states of matter. This homonym has begun to emerge because it can interact with living systems. The physical plasma biomedical applications are reviewed in drug delivery and wound healing medical applications. This approach revolutionizes the therapeutic approaches in medicine and may open up new concepts and clinical applications. The book is an essential source for researchers in the field and provides a platform for different professions.
Author : Jeffrey Kordower
Publisher : Elsevier
ISBN 13 : 9780080556987
Total Pages : 526 pages
Book Rating : 4.5/5 (569 download)
Download or read book CNS Regeneration written by Jeffrey Kordower and published by Elsevier. This book was released on 2011-04-28 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of CNS Regeneration updates the burgeoning field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. While the book covers numerous areas in detail, special emphasis is given to discussions of movement disorders such as Parkinson’s disease, Alzheimer’s disease, and spinal cord injury. Incorporates information gained from cutting-edge photomicroscopy techniques Includes current information on clinical trials Presents chapters on stem cells and other novel treatments for diseases of the CNS
Author : Eduardo E. Benarroch
Publisher : Elsevier Health Sciences
ISBN 13 : 0750675365
Total Pages : 1110 pages
Book Rating : 4.7/5 (56 download)
Download or read book Basic Neurosciences with Clinical Applications written by Eduardo E. Benarroch and published by Elsevier Health Sciences. This book was released on 2006-01-01 with total page 1110 pages. Available in PDF, EPUB and Kindle. Book excerpt: This single-author book covers basic aspects of neuroscience, including concepts of molecular biology, neurochemistry, and electrophysiology, and makes direct clinical correlations in a concise and coherent manner. This concise, coherent text provides a link between basic science and clinical correlations.Readers will benefit from the author's expertise as an academic clinical neurologist.This text provides a concise review of basic neuroscience concepts that are included in several qualifying examinations, including the National Boards.
Author : Jay R. Lieberman
Publisher : Springer Science & Business Media
ISBN 13 : 1592598633
Total Pages : 398 pages
Book Rating : 4.5/5 (925 download)
Download or read book Bone Regeneration and Repair written by Jay R. Lieberman and published by Springer Science & Business Media. This book was released on 2007-10-27 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of articles by leading orthopedic and craniofacial surgeons and researchers comprehensively reviews the biology of bone formation and repair, the basic science of autologous bone graft, allograft, bone substitutes, and growth factors, and explore their clinical application in patients with bone repair problems.
Author :
Publisher : Academic Press
ISBN 13 : 0128201908
Total Pages : 404 pages
Book Rating : 4.1/5 (282 download)
Download or read book Rapid Acting Antidepressants written by and published by Academic Press. This book was released on 2020-06-29 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advances in Pharmacology series presents a variety of chapters from the best authors in the field. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
Author : B. Hamprecht
Publisher : Springer Science & Business Media
ISBN 13 : 3642709400
Total Pages : 221 pages
Book Rating : 4.6/5 (427 download)
Download or read book Neurobiochemistry written by B. Hamprecht and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Humberto Foyaca Sibat
Publisher : BoD – Books on Demand
ISBN 13 : 9535126008
Total Pages : 281 pages
Book Rating : 4.5/5 (351 download)
Download or read book Update on Amyotrophic Lateral Sclerosis written by Humberto Foyaca Sibat and published by BoD – Books on Demand. This book was released on 2016-09-14 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains selected peer-reviewed chapters which cover updated information on ALS written by international researchers. Update on Amyotrophic Lateral Sclerosis is comprised of 13 chapters from some of the world's top central nervous system researchers and neurologists to provide a timely review of the most recent developments in ALS, covering historic aspects, experimental animal models, genetics, pathogenesis, clinical aspects and imagenology among others. Contributors from Belgium, France, Japan, India, Italy, Mexico, Russia, South Africa, and Switzerland have collaborated enthusiastically and efficiently, dedicating their time to create this reader-friendly yet comprehensive work which includes many explanatory figures, tables and photos to enhance legibility and make the book clinically useful. We are looking forward with confidence and pride in the remarkable role that this book will play for a new vision and mission.
Author : Nguyen TK Thanh
Publisher : CRC Press
ISBN 13 : 1351685422
Total Pages : 1408 pages
Book Rating : 4.3/5 (516 download)
Download or read book Clinical Applications of Magnetic Nanoparticles written by Nguyen TK Thanh and published by CRC Press. This book was released on 2018-02-06 with total page 1408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering the latest information in magnetic nanoparticle (MNP) research, this book builds upon the success of the first volume and provides an updated and comprehensive review, from synthesis, characterization, and biofunctionalization to clinical applications of MNPs, including the diagnosis and treatment of cancers. The book captures some of emerging research area which was not available in the first volume. Good Manufacturing Practices and Commercialization of MNPs are also included. This volume, also written by some of the most qualified experts in the field, incorporates new developments in the literature, and continues to bridge the gaps between the different areas in this field.
Author : Francesco Baino
Publisher : BoD – Books on Demand
ISBN 13 : 9535136410
Total Pages : 334 pages
Book Rating : 4.5/5 (351 download)
Download or read book Scaffolds in Tissue EngineeringMaterials, Technologies and Clinical Applications written by Francesco Baino and published by BoD – Books on Demand. This book was released on 2017-12-13 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials are often designed to act as scaffolds, i.e., 3D porous templates that support and stimulate the growth of healthy tissue and then safely dissolve once they have performed their functions. This book provides a picture of the current state of the art in the field of scaffolds for tissue engineering, highlighting the potential associated to the latest scientific and technological advancements. The former part of the book focuses on the repair of "hard" tissues (primarily bone) by means of bioceramic/glass scaffolds, and the latter deals with the applications of polymeric scaffolds for regenerating "soft" tissues and structures including the peripheral nerve, heart, gastric mucosa and pancreas. Special emphasis is given to the challenges associated to scaffold manufacturing, biomimetic properties and cell-scaffold interactions.
