Cell Biology in Environmental Toxicology

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Publisher :
ISBN 13 :
Total Pages : 310 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Cell Biology in Environmental Toxicology by : Miren P. Cajaraville

Download or read book Cell Biology in Environmental Toxicology written by Miren P. Cajaraville and published by . This book was released on 1995 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Biology plays a relevant role in understanding the effects of xenobiotics on organisms and ecosystems because the cell is the site of xenobiotic accumulation, metabolism and reaction, and offers tools and new approaches for the biological assessment of pollution, such as the use of cultured cells in toxicity testing and cellular biomarkers in environmental monitoring. This book comprises reviews of the existing knowledge and new ideas put forward during a course held in the University of the Basque Country in June 1994. It has been designed to provide a rational assessment of current potential methods and concepts to solve problems as well as directions for future research.

Free Radical Biology and Environmental Toxicity

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Publisher : Springer Nature
ISBN 13 : 3030834468
Total Pages : 392 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Free Radical Biology and Environmental Toxicity by : Kavindra Kumar Kesari

Download or read book Free Radical Biology and Environmental Toxicity written by Kavindra Kumar Kesari and published by Springer Nature. This book was released on 2022-03-11 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main aim of this book is to collect a series of research articles and reviews from a diverse group of scientists to share their research work on the role of free radical research and environmental toxicity. This book presents various state-of-the-art chapters of recent progress in the field of cellular toxicology and clinical manifestations of various disorders. Topics include cell signaling, various risk factors, the pathophysiology of disease instigation and distribution, mechanistic insights into metal and nanoparticle toxicity, neural toxicity, nongenotoxic carcinogenicity, immune and idiosyncratic toxicity, prevention, biomarkers related to disease progression and therapeutic strategies. In particular, this book provides valuable insight for researchers, pathologists, and clinicians with an interest in toxicological research and cellular impairments with special emphasis on therapeutic advancement.

Environmental Toxicology

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Publisher : Springer Science & Business Media
ISBN 13 : 1461457645
Total Pages : 737 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Environmental Toxicology by : Edward A. Laws

Download or read book Environmental Toxicology written by Edward A. Laws and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 737 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Toxicology provides a detailed, comprehensive introduction to this key area of sustainability and public health research. The broad coverage includes sections on ecological risk assessment, monitoring, mechanisms, fate and transport, prevention, and correctives, as well as treatment of the health effects of solar radiation and toxicology in the ocean. The 23 state-of-the-art chapters provide a multi-disciplinary perspective on this vital area, which encompasses environmental science, biology, chemistry, and public health.

The Cytoskeleton

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Publisher : Springer Science & Business Media
ISBN 13 : 1461321611
Total Pages : 262 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis The Cytoskeleton by : Thomas W. Clarkson

Download or read book The Cytoskeleton written by Thomas W. Clarkson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on reviews and research presentations given at the 16th Rochester International Conference on Environmental Toxicity, entitled liThe Cytoskeleton: A Target for Toxic Agents," held on June 4, 5 and 6 in 1984. The conference provided an in-depth discussion of the effects a~d mechanism of action of some toxic agents on the cytoskeleton. Mamma"lian and other eukaryotic cells contain protein networks within the cytoplasm comprised of microfilaments, intermediate Hlaments and microtubules. These components of the cytoskeleton playa key role in cell shape, motility, intracellular organization and transport, and cell division. Furthermore, the cytoskeleton, via associations with the cell membrane, appears to function in intracellular communication and cellular responses to membrane events. Because of the complex functional roles of the cytoskeleton which vary with cell type, degree of differentiation, and cell cycle, its disruption may result in a variety of cellular changes. This expanding field in cell biology has already attracted the interest of toxicologists and environmental health scientists as a potentially fruitful area of research. Indeed, there is mounting evidence that certain toxic and chemotherapeutic compounds, as well as physical agents such as radiation and hydrostatic pressure, disrupt the normal structure and function of the cytoskeleton. This may be an important step in the overall expression of their action. It was, therefore, an opportune time to hold a conference to encourage the development of this area of toxicology and to suggest directions for future research.

Systems Biology in Toxicology and Environmental Health

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Publisher : Academic Press
ISBN 13 : 0128015683
Total Pages : 284 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Systems Biology in Toxicology and Environmental Health by : Rebecca Fry

Download or read book Systems Biology in Toxicology and Environmental Health written by Rebecca Fry and published by Academic Press. This book was released on 2015-06-11 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents. Introductory chapters on molecular and cellular biology, toxicology and computational biology are included as well as an assessment of systems-based tools used to evaluate environmental health risks. Further topics include research on environmental toxicants relevant to human health and disease, various high-throughput technologies and computational methods, along with descriptions of the biological pathways associated with disease and the developmental origins of disease as they relate to environmental contaminants. Systems Biology in Toxicology and Environmental Health is an essential reference for undergraduate students, graduate students, and researchers looking for an introduction in the use of systems biology approaches to assess environmental exposures and their impacts on human health. Provides the first reference of its kind, demonstrating the application of systems biology in environmental health and toxicology Includes introductions to the diverse fields of molecular and cellular biology, toxicology, and computational biology Presents a foundation that helps users understand the connections between the environment and health effects, and the biological mechanisms that link them

Environmental Toxicology

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Publisher : Elsevier
ISBN 13 : 9780080458731
Total Pages : 560 pages
Book Rating : 4.4/5 (587 download)

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Book Synopsis Environmental Toxicology by : T.W. Moon

Download or read book Environmental Toxicology written by T.W. Moon and published by Elsevier. This book was released on 2005-02-19 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: This sixth volume in this established series deals with the biochemical responses of fish to different environmental/ecological factors. Environmental Toxicology captures vital issues affecting the responses of fish to the chemical surroundings of their environment. Chapters included in this volume identify the systems found in fish to deal with xenobiotics, hormonal interactions initiated in the presence of these chemicals, the unique mechanisms used by fish to adjust to the present chemicals, and the new and evolving mixtures of chemicals in their environment. Also included, is a crucial review of the new methods being applied in fish systems to understand the effects of xenobiotics to fish fitness - a key theme in environmental health and critical to the future of fish populations. * Entirely new topic discussion and most recent volume in the acclaimed series * Includes chapters detailed on a cellular level * Introduces discussion of pharmaceutical effects on fish

Environmental Cell Biology

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Publisher : Addison Wesley Longman
ISBN 13 :
Total Pages : 138 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Environmental Cell Biology by : John L. Howland

Download or read book Environmental Cell Biology written by John L. Howland and published by Addison Wesley Longman. This book was released on 1975 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular and Biochemical Toxicology

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Publisher : John Wiley & Sons
ISBN 13 : 1118679725
Total Pages : 804 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Molecular and Biochemical Toxicology by : Robert C. Smart

Download or read book Molecular and Biochemical Toxicology written by Robert C. Smart and published by John Wiley & Sons. This book was released on 2013-03-05 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential resource for graduate students, academic and industrial toxicologists, and environmental health scientists and professionals Over the course of thirty years and three editions, Introduction to Biochemical Toxicology has been an important source for coverage of the ongoing quest to define the biochemical, cellular, and molecular events induced by toxicants at the cellular and organismic levels. Now, as the principles and methods of molecular and cellular biology as well as genomic sciences play an ever increasing role in mechanistic toxicology, significant changes have been made to the book, resulting in this important new edition-now titled Molecular and Biochemical Toxicology, Fourth Edition. Much more than an introductory text, this crucial new edition has been completely revised to provide timely and thorough coverage of the underlying biochemical, molecular, and cellular mechanisms through which toxicants produce their adverse effects. Toxicological issues are covered from the molecule to the cell to the organ level. Complex methods used in toxicology are also described in a straightforward, easy-to-understand style. Additional features of this new edition include: New chapters that explore the interface between toxicology and genomic sciences, including: bioinformatics, proteomics, metabolomics, and toxicogenomics Increased emphasis on structure, mechanism, and regulation of xenobiotic metabolizing enzymes, toxicogenetics, and xenobiotic transporters Additional new chapters on: molecular epidemiology and genetic susceptibility, DNA damage and mutagenesis, DNA repair, mechanisms of cell death, mitochondrial dysfunction, metals, reproductive toxicology, developmental toxicology, and reactive oxygen/metabolites and toxicity Molecular and Biochemical Toxicology, Fourth Edition guides graduate students, toxicologists, and environmental health professionals through the principles of molecular and biochemical toxicology and the complex mechanisms of toxicity. Whether it's used in the classroom or in industry, research, or academia, this book is essential for anyone interested in understanding the molecular mechanisms through which toxicants produce adverse effects.

Aquatic Toxicology

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Publisher : CRC Press
ISBN 13 : 1351078321
Total Pages : 553 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Aquatic Toxicology by : Donald C. Malins

Download or read book Aquatic Toxicology written by Donald C. Malins and published by CRC Press. This book was released on 2018-01-18 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aquatic Toxicology examines research findings on the chronic effects of pollutants on aquatic species. Understanding these chronic effects is vital to determining the impact of small concentrations of pollutants on aquatic life in rivers, estuaries, lakes, and coastal waters. Featuring research from renowned experts in the field, this book evaluates modern techniques in the fields of molecular biology and biochemistry. It is indispensable to aquatic toxicologists, aquatic biochemists, fisheries scientists, industrial chemists, and researchers at federal, state, and university levels.

Small-scale Freshwater Toxicity Investigations

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Publisher : Springer Science & Business Media
ISBN 13 : 1402031203
Total Pages : 563 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Small-scale Freshwater Toxicity Investigations by : Christian Blaise

Download or read book Small-scale Freshwater Toxicity Investigations written by Christian Blaise and published by Springer Science & Business Media. This book was released on 2006-01-16 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: This broad review is the first to gather comprehensive information on the complete contemporary range of toxicity testing procedures and hazard assessment procedures, which is normally scattered and difficult to find. The two-volume set provides a consistent, template-based approach, linking relevant information on background, theory and practice to each bioassay. Volume 1 covers small-scale toxicity test methods. Includes extensive glossary.

Cell Culture Methods for In Vitro Toxicology

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Publisher : Springer Science & Business Media
ISBN 13 : 9781402004278
Total Pages : 166 pages
Book Rating : 4.0/5 (42 download)

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Book Synopsis Cell Culture Methods for In Vitro Toxicology by : Glyn Stacey

Download or read book Cell Culture Methods for In Vitro Toxicology written by Glyn Stacey and published by Springer Science & Business Media. This book was released on 2001-12-31 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies. It deals with major cell types studied in the field of toxicology and will be useful for anyone wishing to start work with animal cell cultures or to refresh their knowledge relating to in vitro cell models. Fundamental chapters deal with the general biology of cytotoxicity and cell immortalisation these are key issues for in vitro systems addressing the `3Rs' principle. Up-to-date overviews deal with the use of cells from liver, brain and intestine. In addition, biochemical analysis of cell responses, biotransformation pathways in cells and recombinant approaches to the early detection of cell stress are also covered in detail. Prominent features of in vitro technologies also include regulation, biosafety and standardisation. Dedicated chapters deal with these issues in a practical way in order to lead the reader to the right source of information. This book provides an up-to-date, informative and practical review of cell culture methods for in vitro toxicology. It will be of equal benefit to students and experienced toxicologists with little experience of in vitro cell culture.

Cellular and Molecular Toxicology

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Publisher : Gulf Professional Publishing
ISBN 13 : 9780444508683
Total Pages : 674 pages
Book Rating : 4.5/5 (86 download)

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Book Synopsis Cellular and Molecular Toxicology by : J.P. Vanden Heuvel

Download or read book Cellular and Molecular Toxicology written by J.P. Vanden Heuvel and published by Gulf Professional Publishing. This book was released on 2002-02-14 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 14 in the series Comprehensive Toxicology extends and complements the previously published 13-volume set. This volume will be available separately. Toxicology is the study of the nature and actions of chemicals on biological systems. In more primitive times, it really was the study of poisons. However, in the early 1500s, it was apparent to Paracelsus that "the dose differentiates a poison and a remedy". Clearly, the two most important tenets of toxicology were established during that time. The level of exposure (dose) and the duration of exposure (time) will determine the degree and nature of a toxicological response. Since that time the discipline of toxicology has made major advances in identifying and characterizing toxicants. The growth of toxicology as a scientific discipline has been driven to a large extent by the use of extremely powerful molecular and cell biology techniques. The overall aim of this volume is to demonstrate how these advances are being used to elucidate causal pathways (or linkages) for potential adverse health consequences of human exposure to environmental chemicals or radiation. A unique feature of this volume is its illustration of how carefully-designed studies of the molecular mechanisms of chemical action provide not only understanding of the potential toxicity of the chemical under investigation, but also new insights into the functioning of the biological system used as an experimental model. Each chapter contains a listing of major peer-reviewed articles and reviews and useful web-sites. In addition, each chapter contains a broad introductory section that outlines the subsequent sections. These Introductory and Overview sections are designed to be stand alone chapters, and may be packaged as a textbook in graduate level courses.

Toxicology of the Human Environment

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Publisher :
ISBN 13 : 9780367804770
Total Pages : 512 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Toxicology of the Human Environment by : Christopher J. Rhodes

Download or read book Toxicology of the Human Environment written by Christopher J. Rhodes and published by . This book was released on 2000 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The environment in which human beings live is complex and we may encounter many different potentially toxic chemical substances during the course of our lives. These xenobiotic agents may invade the living system in the form of environmental pollutants, in the diet, as pharmaceutically administered compounds or even as chemical weapons and it is becoming widely recognised that free radicals are often involved in this toxicity.The book covers all aspects of toxic agents in the environment from their detection to their effects. Final year undergraduates and postgraduates studying toxicology, biochemistry, cell biology or environmental science will find this book valuable reading, whilst researchers in academia, the pharmaceutical industry, and public health laboratories will appreciate it as a comprehensive reference.

In vitro Environmental Toxicology - Concepts, Application and Assessment

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Publisher : Springer
ISBN 13 : 3319459082
Total Pages : 324 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis In vitro Environmental Toxicology - Concepts, Application and Assessment by : Georg Reifferscheid

Download or read book In vitro Environmental Toxicology - Concepts, Application and Assessment written by Georg Reifferscheid and published by Springer. This book was released on 2017-05-16 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science.Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification.In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

DNA Replication - Damage from Environmental Carcinogens

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Publisher : Springer
ISBN 13 : 9401772126
Total Pages : 43 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis DNA Replication - Damage from Environmental Carcinogens by : Huidong Zhang

Download or read book DNA Replication - Damage from Environmental Carcinogens written by Huidong Zhang and published by Springer. This book was released on 2015-05-25 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the main concepts concerning DNA damage due to environmental carcinogens, the effects of DNA damage on DNA replication using a single DNA polymerase or DNA replisome, and the effects of carcinogens on various cell activities. It also introduces the detailed protocols for bypassing DNA damage. As we know, various environmental carcinogens are produced as a result of industry, agriculture, chemical engineering and vehicle exhaust in our daily life. It has been reported that the environmental carcinogens can be connected to tumors and cancer, directly threatening human health. In this regard, DNA replication is highly susceptible to damage. This book provides graduate students and researchers with an overview of the effects of environmental carcinogens on DNA replication and biological activities in cells. It offers important information for research in the areas of biochemistry, cell biology, medicine, toxicology and public health.

Essentials Of Environmental Toxicology

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Publisher : CRC Press
ISBN 13 : 0203362799
Total Pages : 189 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Essentials Of Environmental Toxicology by : William Hughes

Download or read book Essentials Of Environmental Toxicology written by William Hughes and published by CRC Press. This book was released on 2003-09-02 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This introductory text addresses the principles and mechanisms of toxicology as applied to environmentally-encountered toxic agents. Each chapter concludes with review questions that may be used for student self-testing and topics covered include dose response, hazards and risk assessment, determination of toxicity, pesticides, metals, plastics, organic solvents, environmental carcinogens, teratogens and mutagens.

Mechanistic Toxicology

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Publisher : CRC Press
ISBN 13 : 9780849372728
Total Pages : 424 pages
Book Rating : 4.3/5 (727 download)

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Book Synopsis Mechanistic Toxicology by : Urs A. Boelsterli

Download or read book Mechanistic Toxicology written by Urs A. Boelsterli and published by CRC Press. This book was released on 2007-03-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology