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Author : Dennis Cooper
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (16 download)
Download or read book Towards the Rapid and Efficient Stereoselective Synthesis of Tetrahydropyrans written by Dennis Cooper and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kiyoun Lee
Publisher : Springer
ISBN 13 : 3319044621
Total Pages : 198 pages
Book Rating : 4.3/5 (19 download)
Download or read book Stereoselective Syntheses of Tetrahydropyrans written by Kiyoun Lee and published by Springer. This book was released on 2014-07-08 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: In his thesis, Kiyoun Lee describes his studies into tandem and organocatalytic oxa-conjugate addition reactions for the synthesis of complex tetrahydropyrans (THP). Readers gain insight into the new methods Lee employs for the synthesis of biologically interesting natural products including (+)-leucascandrolide A, (+)-dactylolide, and (±)diospongin A. The reactions Lee investigates are applicable to a broad range of substrates and proceed with excellent stereoselectivity. Moreover, the methodologies allow the synthesis of a wide range of THP-containing compounds. The development of reactions, such as those discussed by Lee, has the potential to impact natural product synthesis, pharmaceutical development and chemical biology.
Author : Mihály Nógrádi
Publisher : John Wiley & Sons
ISBN 13 : 3527615687
Total Pages : 386 pages
Book Rating : 4.5/5 (276 download)
Download or read book Stereoselective Synthesis written by Mihály Nógrádi and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: The state-of-the-art in stereoselective synthesis! Thoroughly revised and updated, this enlarged second edition offers a plethora of valuable information on methods and reagents in stereoselective synthesis. Methods have been selected for high efficiency and selectivity; mechanistic aspects are treated succinctly, with a strong emphasis on practical applications. For this new edition, material has been added on * homogeneous diastereoselective hydrogenations * enantioselective oxidations * novel, efficient chiral auxiliaries Much of the information given is presented in figures and tables, which makes the book a valuable reference work for the practically minded organic chemist. From reviews of the first edition: 'The extensive material in the volume should prove particularly useful to anyone involved in synthetic chemistry or teaching a course in organic chemistry.' Journal of Medicinal Chemistry 'With nearly 1400 references cited, the book contains a wealth of information and should be a useful addition to the chemist's library.' The American Scientist
Author : Eckhard Ottow
Publisher : Springer Science & Business Media
ISBN 13 : 3642784968
Total Pages : 147 pages
Book Rating : 4.6/5 (427 download)
Download or read book Stereoselective Synthesis written by Eckhard Ottow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Devising methods and reagents for stereoselective synthesis is an intellectually demanding venture. Six experts on diastereo- and enantioselective synthesis contributed their papers to this volume. They were presented at a symposium on stereoselective synthesis to honour Professor Dr. Dr. h.c. Rudolf Wiechert's achievements in medicinal chemistry research. The symposium was organized by the Schering AG on the occasion of Professor Wiechert's 65th birthday.
Author : Nahla Ahmed Elsaid
Publisher :
ISBN 13 :
Total Pages : 356 pages
Book Rating : 4.3/5 (121 download)
Download or read book Stereoselective Synthesis of Tetrahydrofurans and Tetrahydropyrans written by Nahla Ahmed Elsaid and published by . This book was released on 2001 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Erick M. Carreira
Publisher : Wiley-VCH
ISBN 13 : 9783527299669
Total Pages : 0 pages
Book Rating : 4.2/5 (996 download)
Download or read book Classics in Stereoselective Synthesis written by Erick M. Carreira and published by Wiley-VCH. This book was released on 2009-02-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a noteworthy compilation of the groundbreaking methods of stereoselective synthesis, belonging to the repertoire of every modern practitioner of synthetic organic chemistry. The general principles underlying these processes are highlighted as they form the basis for the rapid and continuing developments in the field. The work also features illustrative examples of drug and natural product syntheses, resulting in a rich source of stimulating ideas for the efficient use of asymmetric reactions in the construction of stereochemically complex structures. From the contents: "Macrocyclic stereocontrol "Carbonyl addition reactions "alpha-Functionalization of enolates "Aldol and allylation reactions "Chiral acetals "Alkene hydroboration, reduction, and oxidation "Additions to C=N bonds and synthesis of amino acids "Conjugate additions "Chiral carbanions "Metal-catalyzed allylations "Cyclopropanations and CH-insertion reactions "Sigmatropic rearrangements "Diels-Alder and hetero-Diels-Alder reactions "[3+2]- and [2+2]-cycloaddition reactions
Author : Megan Lesley Bolla
Publisher :
ISBN 13 : 9780549714866
Total Pages : 286 pages
Book Rating : 4.7/5 (148 download)
Download or read book Stereoselective Synthesis of Highly Functionalized Tetrahydropyran Rings written by Megan Lesley Bolla and published by . This book was released on 2008 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Described in this dissertation are several methods developed for the stereoselective synthesis of tetrahydropyrans rings. Initially, an effort to expand the Mukaiyama Aldol-Prins cyclization reaction to disubstituted (E)-enol ethers was explored. The Mukaiyama-Michael cascade reaction was then discovered by a fortuitous result. Investigating this method provided an unexpected tetrahydropyran product containing 2,6-trans geometry, and is rationalized considering both steric and electronic effects. Finally, a two-step [4+2] inverse demand HDA annulation reaction and rearrangement was developed for the diastereoselective synthesis of 2,4,5,6- tetra-substituted tetrahydropyran rings.
Author : Gregory Dominic Parker
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (591 download)
Download or read book The Stereoselective Synthesis of Substituted Tetrahydropyrans Using Acid-promoted Prins Cyclisations written by Gregory Dominic Parker and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Vasyl Andrushko
Publisher : John Wiley & Sons
ISBN 13 : 1118628330
Total Pages : 1836 pages
Book Rating : 4.1/5 (186 download)
Download or read book Stereoselective Synthesis of Drugs and Natural Products written by Vasyl Andrushko and published by John Wiley & Sons. This book was released on 2013-08-16 with total page 1836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.
Download or read book M-CPBA-mediated Stereoselective Synthesis of Sulfonyl Tetrahydropyrans written by and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Navjeet Kaur
Publisher : Elsevier
ISBN 13 : 0128202831
Total Pages : 526 pages
Book Rating : 4.1/5 (282 download)
Download or read book Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles written by Navjeet Kaur and published by Elsevier. This book was released on 2020-04-25 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles provides a useful guide to key approaches being explored in this area. The volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Drawing on the experience of its expert author, the book is a useful guide on the key approaches being explored in this area. Following a user-friendly structure based on specific six-membered heterocycle ring groups, this volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Highlights new methodologies for the synthesis of different six-membered heterocycles Provides an up-to-date overview of this fast-moving field with an easy-to-use structure Includes novel approaches used in the study and application of catalysts in synthetic organic reactions
Author : Jean Rodriguez
Publisher : John Wiley & Sons
ISBN 13 : 1118672712
Total Pages : 472 pages
Book Rating : 4.1/5 (186 download)
Download or read book Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis written by Jean Rodriguez and published by John Wiley & Sons. This book was released on 2015-04-27 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining the important research topic of multiple bond-forming transformations with green chemistry, this book helps chemists identify recent sustainable stereoselective synthetic sequences. • Combines the important research topic of multiple bond-forming transformations with green chemistry and sustainable development • Offers a valuable resource for preparing compounds with multiple stereogenic centers, an important field for synthetic chemists • Organizes chapters by molecular structure of final products, making for a handbook-style resource • Discusses applications of the synthesis of natural products and of drug intermediates • Brings together otherwise-scattered information about a number of key, efficient chemical reactions
Author : Navjeet Kaur
Publisher : CRC Press
ISBN 13 : 1000733416
Total Pages : 404 pages
Book Rating : 4.0/5 (7 download)
Download or read book Metals and Non-metals written by Navjeet Kaur and published by CRC Press. This book was released on 2020-01-28 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design of new processes that avoid the use of toxic reagents has been the focus of intense research of late. Catalysis by metals and non-metals offers diverse opportunities for the development of new organic reactions with promising range of selectivities—chemoselectivity, regioselectivity, diastereoselectivity, and enantioselectivity. Furthermore, these transformations frequently occur under mild conditions, tolerate a broad array of functional groups, and proceed with high stereoselectivity. The area of catalysis is sometimes referred to as a ‘foundational pillar’ of green chemistry. Catalytic reactions often reduce energy requirements and decrease separations because of increased selectivity; they are also capable of permitting the use of renewable feedstocks of less toxic reagents or minimizing the quantities of reagents needed. New catalytic organic synthesis methodologies have, thus, offered several possibilities for considerable improvement in the eco-compatibility of fine chemical production. Hence, these catalytic methodologies have emerged as powerful tools for the efficient and chemoselective synthesis of heterocyclic molecules. Key Features: Presents the synthesis of different five-membered heterocycles. Contains the most up-to-date information in this fast-moving field. Covers novel catalytic approaches used in the study and application of catalysts in synthetic organic reactions. Presents new methodologies for the synthesis of heterocycles.
Author : Masahisa Nakada
Publisher : Springer Nature
ISBN 13 : 9819716195
Total Pages : 518 pages
Book Rating : 4.8/5 (197 download)
Download or read book Modern Natural Product Synthesis written by Masahisa Nakada and published by Springer Nature. This book was released on with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 860 pages
Book Rating : 4.F/5 ( download)
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2003 with total page 860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lutz H. Gade
Publisher : John Wiley & Sons
ISBN 13 : 3527673296
Total Pages : 632 pages
Book Rating : 4.5/5 (276 download)
Download or read book Molecular Catalysts written by Lutz H. Gade and published by John Wiley & Sons. This book was released on 2014-06-30 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highlighting the key aspects and latest advances in the rapidly developing field of molecular catalysis, this book covers new strategies to investigate reaction mechanisms, the enhancement of the catalysts' selectivity and efficiency, as well as the rational design of well-defined molecular catalysts. The interdisciplinary author team with an excellent reputation within the community discusses experimental and theoretical studies, along with examples of improved catalysts, and their application in organic synthesis, biocatalysis, and supported organometallic catalysis. As a result, readers will gain a deeper understanding of the catalytic transformations, allowing them to adapt the knowledge to their own investigations. With its ideal combination of fundamental and applied research, this is an essential reference for researchers and graduate students both in academic institutions and in the chemical industry. With a foreword by Nobel laureate Roald Hoffmann.
Author :
Publisher :
ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.3/5 (91 download)
Download or read book Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by and published by . This book was released on 2008 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
