Stereoselective Synthesis of Drugs and Natural Products

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118628330
Total Pages : 1836 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Stereoselective Synthesis of Drugs and Natural Products by : Vasyl Andrushko

Download or read book Stereoselective Synthesis of Drugs and Natural Products written by Vasyl Andrushko and published by John Wiley & Sons. This book was released on 2013-08-16 with total page 1836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.

Stereoselective Synthesis of Drugs and Natural Products, 2 Volume Set

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Author :
Publisher : Wiley
ISBN 13 : 9781118032176
Total Pages : 0 pages
Book Rating : 4.0/5 (321 download)

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Book Synopsis Stereoselective Synthesis of Drugs and Natural Products, 2 Volume Set by : Vasyl Andrushko

Download or read book Stereoselective Synthesis of Drugs and Natural Products, 2 Volume Set written by Vasyl Andrushko and published by Wiley. This book was released on 2013-10-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.

Stereoselective Synthesis of Drugs and Natural Products, Two Volume Set

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (999 download)

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Book Synopsis Stereoselective Synthesis of Drugs and Natural Products, Two Volume Set by : Vasyl Andrushko

Download or read book Stereoselective Synthesis of Drugs and Natural Products, Two Volume Set written by Vasyl Andrushko and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Classics in Stereoselective Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 9783527324521
Total Pages : 664 pages
Book Rating : 4.3/5 (245 download)

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Book Synopsis Classics in Stereoselective Synthesis by : Erick M. Carreira

Download or read book Classics in Stereoselective Synthesis written by Erick M. Carreira and published by John Wiley & Sons. This book was released on 2009-02-09 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die wichtigsten und nützlichsten Methoden der modernen stereoselektiven Synthese sind in diesem Band zusammengefasst. Viele anschauliche Beispiele für die Darstellung von Wirkstoffen und Naturstoffen regen zur gezielten Abwandlung und Integration in eigene Synthesewege an. Dabei geht es den Autoren weniger darum, das Gebiet in seiner Gesamtheit darzustellen; vielmehr versuchen sie, die wirklich grundlegenden Ansätze auszuwählen, die jeder organische Synthesechemiker kennen und anwenden sollte.

Studies in Natural Products Chemistry

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Author :
Publisher : Elsevier
ISBN 13 : 1483100979
Total Pages : 730 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Studies in Natural Products Chemistry by : Atta-ur- Rahman

Download or read book Studies in Natural Products Chemistry written by Atta-ur- Rahman and published by Elsevier. This book was released on 2013-10-22 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies in Natural Products Chemistry, Volume 10: Stereoselective Synthesis (Part F) is a collection of articles about studies on important organic molecules. The book covers studies such as that on the synthesis of cembranes as well as its natural occurrence and bioactivity; the stereoselective synthesis of Vitamin D; the synthesis of isoquinolinequinone antibiotics; and the nucleophilic addition chemistry of polyunsaturated carbonyl compounds. Also covered in the book are subjects such as developments in the synthesis of medium ring ethers; the biological properties, chemistry, and synthesis of didemnins; and natural products synthesis based on novel ring transformation. The text is recommended for organic chemists who would like to know more about the progresses in the study of important organic molecules and their implications in different fields.

Stereoselective Synthesis

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642784968
Total Pages : 147 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Stereoselective Synthesis by : Eckhard Ottow

Download or read book Stereoselective Synthesis written by Eckhard Ottow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Devising methods and reagents for stereoselective synthesis is an intellectually demanding venture. Six experts on diastereo- and enantioselective synthesis contributed their papers to this volume. They were presented at a symposium on stereoselective synthesis to honour Professor Dr. Dr. h.c. Rudolf Wiechert's achievements in medicinal chemistry research. The symposium was organized by the Schering AG on the occasion of Professor Wiechert's 65th birthday.

Stereoselective Synthesis in Organic Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 1461383277
Total Pages : 534 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Stereoselective Synthesis in Organic Chemistry by : Atta-ur-Rahman

Download or read book Stereoselective Synthesis in Organic Chemistry written by Atta-ur-Rahman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Studies in Natural Products Chemistry

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Author :
Publisher : Elsevier
ISBN 13 : 1483163539
Total Pages : 938 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Studies in Natural Products Chemistry by : Atta-ur-Rahman

Download or read book Studies in Natural Products Chemistry written by Atta-ur-Rahman and published by Elsevier. This book was released on 2013-10-22 with total page 938 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies in Natural Products Chemistry, Volume 14: Stereoselective Synthesis, Part I is a collection of discourses on the stereoselective synthesis of the anticancer anthrucycline antibiotics; tetramic acid antibiotics; 3-and 4-deoxyhexoses; polysaccharides; levoglucosenone as precursor to natural products; synthesis of oligoribonucleotides; and oxidation of guaiazulene. This volume deals with a broad range of natural products focusing on the synthesis of antibiotics and anticancer agents — anthracyclines, tetramic acid, taxodione, vinblastine, and vincristine. These aforementioned drugs are used for the treatment of cancer (anthracyclines) and Hodgkin's disease and childhood acute leukemia (vinblastine and vincristine). The importance of the latest developments in the stereocontrolled synthesis of polysaccharides is discussed as polysaccharides play a fundamental role in cell life and have many technical applications. The synthesis of bioactive carbohydrates 3- and 4-deoxy-hexoses is compared with the more occurring deoxyhexoses in nature such as the 2-deoxy, 6-deoxy, and 2,6-dideoxy-hexoses, because the former are rare compounds and useful tools in the study of biological and biochemical properties of mono- and oligosaccharides, glycoproteins, and antibiotics. Alkaloids derived from Apocynaceae are known for their medicinal properties; hence the synthetic approaches to vinblastine and vincristine are discussed. Because of the minute amounts available from herbal sources, efforts toward their chemical synthesis are given more reference. This book can be a useful reference for the organic chemists. Chemical researchers, pharmaceutical scientists, and professionals of bioorganic chemistry will likewise gain a lot from this collection.

Studies in Natural Products Chemistry

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Author :
Publisher : Elsevier
ISBN 13 : 9780080541778
Total Pages : 1108 pages
Book Rating : 4.5/5 (417 download)

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Book Synopsis Studies in Natural Products Chemistry by : Atta-ur-Rahman

Download or read book Studies in Natural Products Chemistry written by Atta-ur-Rahman and published by Elsevier. This book was released on 1996-05-01 with total page 1108 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Volume 18 of this well-established series, Professor Atta-ur-Rahman again brings together the work of several of the world's leading authorities in organic chemistry. Their contributions demonstrate the rapid, ongoing development of this field by illustrating many of the latest advances in synthetic methods, total synthesis, structure determination, biosynthetic pathways, and biological activity. The opening chapter presents an overview of strategies for the synthesis of several classes of natural products with an emphasis on complex polycyclic systems. Subsequent chapters discuss the synthesis of specific classes of compounds, including morphine, polyketides, acetogenins, nonactic acid derivatives, complex spirocyclic ethers, ä-lactam and pyridone derivatives, inositol phosphates, sphingolipids, brassinosteroids, Hernandia lignans, and dimeric steroidal pyrazine alkaloids. Finally, the ever stronger links between chemistry and biology are reinforced by chapters on the origin and function of secondary metabolites, bioactive conformations of gastrin hormones, and immunochemistry.

Studies in Natural Products Chemistry

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Author :
Publisher : Elsevier
ISBN 13 : 1483193241
Total Pages : 540 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Studies in Natural Products Chemistry by : Atta-ur-Rahman

Download or read book Studies in Natural Products Chemistry written by Atta-ur-Rahman and published by Elsevier. This book was released on 2013-10-22 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies in Natural Products Chemistry Volume 12: Stereoselective Synthesis (Part H) reviews the stereoselective synthetic and mechanistic chemistry of bicyclomycin. It discusses chemical studies of the taxane diterpenes; the synthetic methodology for 2-amino alcohols of biological interest; and the synthesis and structure of hydroxylated indolizidines. Some of the topics covered in the book are the synthetic routes to the oxahydrindene subunit of the avermectin-milbemycin family of antiparasitic agents; isolation, structure elucidation, biosynthesis, and biological activity of the avermectins; two-stage coupling process of macrolide antibiotics synthesis; and synthesis of the rifamycin S ansa-chain compound. The complete synthesis of erythromycin A is also covered. The role of isocyanides in the synthesis of beta lactam antibiotics and the characteristics of the beta lactam antibiotics are discussed. The development of an A-Ring annulation strategy for taxane synthesis is also presented. A chapter is devoted to the advances in the synthesis of tumor-promoting diterpenes. The book can provide useful information to chemists, biologists, students, and researchers.

Stereoselective Synthesis

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Publisher :
ISBN 13 :
Total Pages : 756 pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis Stereoselective Synthesis by :

Download or read book Stereoselective Synthesis written by and published by . This book was released on 1989 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stereoselective Synthesis

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Author :
Publisher : Elsevier Science & Technology
ISBN 13 : 9780444872982
Total Pages : 564 pages
Book Rating : 4.8/5 (729 download)

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Book Synopsis Stereoselective Synthesis by : Atta-ur- Rahman

Download or read book Stereoselective Synthesis written by Atta-ur- Rahman and published by Elsevier Science & Technology. This book was released on 1989 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Section 1

Stereoselective Synthesis

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Author :
Publisher : Elsevier Science & Technology
ISBN 13 : 9780444880338
Total Pages : 776 pages
Book Rating : 4.8/5 (83 download)

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Book Synopsis Stereoselective Synthesis by : Atta-ur Rahman

Download or read book Stereoselective Synthesis written by Atta-ur Rahman and published by Elsevier Science & Technology. This book was released on 1989 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: Section 1

Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119006422
Total Pages : 480 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis by : Jean Rodriguez

Download or read book Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis written by Jean Rodriguez and published by John Wiley & Sons. This book was released on 2015-04-08 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining the important research topic of multiple bond-forming transformations with green chemistry, this book helps chemists identify recent sustainable stereoselective synthetic sequences. • Combines the important research topic of multiple bond-forming transformations with green chemistry and sustainable development • Offers a valuable resource for preparing compounds with multiple stereogenic centers, an important field for synthetic chemists • Organizes chapters by molecular structure of final products, making for a handbook-style resource • Discusses applications of the synthesis of natural products and of drug intermediates • Brings together otherwise-scattered information about a number of key, efficient chemical reactions

Studies in Natural Products Chemistry

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Author :
Publisher : Elsevier
ISBN 13 : 9780080541785
Total Pages : 772 pages
Book Rating : 4.5/5 (417 download)

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Book Synopsis Studies in Natural Products Chemistry by : Atta-ur-Rahman

Download or read book Studies in Natural Products Chemistry written by Atta-ur-Rahman and published by Elsevier. This book was released on 1995-08-10 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies in Natural Products Chemistry

Stereoselective Synthesis

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Author :
Publisher : Elsevier Science Limited
ISBN 13 : 9780444872982
Total Pages : 543 pages
Book Rating : 4.8/5 (729 download)

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Book Synopsis Stereoselective Synthesis by : Atta-ur Rahman

Download or read book Stereoselective Synthesis written by Atta-ur Rahman and published by Elsevier Science Limited. This book was released on 1989 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second volume to be devoted to the area of stereoselective synthesis. It reviews and highlights important and new contributions by eminent scientists on a wide variety of organic reactions and strategies to the stereoselective synthesis of complex structures which will provide stimulating reading for many synthetic organic chemists.

Stereoselective Synthesis

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Author :
Publisher : Elsevier Science Limited
ISBN 13 : 9780444822642
Total Pages : 757 pages
Book Rating : 4.8/5 (226 download)

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Book Synopsis Stereoselective Synthesis by : Atta-ur- Rahman

Download or read book Stereoselective Synthesis written by Atta-ur- Rahman and published by Elsevier Science Limited. This book was released on 1995-01-01 with total page 757 pages. Available in PDF, EPUB and Kindle. Book excerpt: Section 1