The Rhesus Monkey Brain In Stereotaxic Coordinates

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The Rhesus Monkey Brain in Stereotaxic Coordinates

Author : George Paxinos
Publisher : Academic Press
ISBN 13 : 0128158530
Total Pages : 394 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Rhesus Monkey Brain in Stereotaxic Coordinates by : George Paxinos

Download or read book The Rhesus Monkey Brain in Stereotaxic Coordinates written by George Paxinos and published by Academic Press. This book was released on 2024-03-01 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paxinos and Petrides' The Rhesus Monkey Brain in Stereotaxic Coordinates is the most comprehensive and accurate atlas of the monkey brain currently available. The fourth edition of this classic book will be a complete revision, featuring many improvements and upgrades. Containing coronal diagrams and accompanying photographic plates spaced at 120 μm intervals, this atlas follows the same nomenclature and abbreviations conventions as the mouse, rat, chicken, and human brain atlases published under George Paxinos’ leadership. This atlas is suitable for researchers who work with both monkeys and humans. Constructed by the established leaders in neuroanatomical atlas development, the new edition will again be the indispensable resource for all scientists working on the primate nervous system. 141 completely revised coronal diagrams and accompanying colour photographic plates spaced at approximately 120 μm intervals 60 colour photographic coronal plates of SMI immunoreactivity with completely revised delineations Includes MR images at approximately the same levels as the coronal diagrams Follows the same nomenclature and abbreviations as the mouse, rat, chicken, marmoset and human brain atlases, with indications of correspondence to alternative macaque nomenclatures This atlas was used for the delineation and nomenclature of MRI-based macaque brain atlases for neuroimaging analyses, including the SARM

A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates

Author : Kadharbatcha S. Saleem
Publisher : Academic Press
ISBN 13 : 0123850878
Total Pages : 402 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates by : Kadharbatcha S. Saleem

Download or read book A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates written by Kadharbatcha S. Saleem and published by Academic Press. This book was released on 2012-04-23 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates, Second Edition maps the detailed architectonic subdivisions of the cortical and subcortical areas in the macaque monkey brain using high-resolution magnetic resonance (MR) images and the corresponding histology sections in the same animal. This edition of the atlas is unlike anything else available as it includes the detailed cyto- and chemoarchitectonic delineations of the brain areas in all three planes of sections (horizontal, coronal, and sagittal) that are derived from the same animal. This is a significant progress because in functional imaging studies, such as fMRI, both the horizontal and sagittal planes of sections are often the preferred planes given that multiple functionally active regions can be visualized simultaneously in a single horizontal or sagittal section. This combined MRI and histology atlas is designed to provide an easy-to-use reference for anatomical and physiological studies in macaque monkeys, and in functional-imaging studies in human and non-human primates using fMRI and PET. The first rhesus monkey brain atlas with horizontal, coronal, and sagittal planes of sections, derived from the same animal Shows the first detailed delineations of the cortical and subcortical areas in horizontal, coronal, and sagittal plane of sections in the same animal using different staining methods Horizonal series illustrates the dorsoventral extent of the left hemisphere in 47 horizontal MRI and photomicrographic sections matched with 47 detailed diagrams (Chapter 3) Coronal series presents the full rostrocaudal extent of the right hemisphere in 76 coronal MRI and photomicrographic sections, with 76 corresponding drawings (Chapter 4) Sagittal series shows the complete mediolateral extent of the left hemisphere in 30 sagittal MRI sections, with 30 corresponding drawings (Chapter 5). The sagittal series also illustrates the location of different fiber tracts in the white matter Individual variability - provides selected cortical and subcortical areas in three-dimensional MRI (horizontal, coronal, and sagittal MRI planes). For comparison, it also provides similar areas in coronal MRI section in six other monkeys. (Chapter 6) Vasculature - indicates the corresponding location of all major blood vessels in horizontal, coronal, and sagittal series of sections Provides updated information on the cortical and subcortical areas, such as architectonic areas and nomenclature, with references, in chapter 2 Provides the sterotaxic grid derived from the in-vivo MR image

The Mouse Brain in Stereotaxic Coordinates: Compact Second Edition

Author : George Paxinos
Publisher : Academic Press
ISBN 13 : 9780125476409
Total Pages : 0 pages
Book Rating : 4.4/5 (764 download)

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Book Synopsis The Mouse Brain in Stereotaxic Coordinates: Compact Second Edition by : George Paxinos

Download or read book The Mouse Brain in Stereotaxic Coordinates: Compact Second Edition written by George Paxinos and published by Academic Press. This book was released on 2003-11-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mouse Brain in Stereotaxic Coordinates, Second Edition has been the acknowledged reference in this field since the publication of the first edition, and is now available in a Compact Edition. This will provide a more affordable option for students, as well as researchers needing an additional lab atlas. This version includes the coronal diagrams delineating the entire brain as well as the introductory text from the Deluxe edition. It is an essential reference for anyone studying the mouse brain or related species.

Magnetic Resonance Imaging of the Rhesus Monkey Brain

Author : Roland Tammer
Publisher : Vandenhoeck & Ruprecht
ISBN 13 : 9783525404249
Total Pages : 0 pages
Book Rating : 4.4/5 (42 download)

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Book Synopsis Magnetic Resonance Imaging of the Rhesus Monkey Brain by : Roland Tammer

Download or read book Magnetic Resonance Imaging of the Rhesus Monkey Brain written by Roland Tammer and published by Vandenhoeck & Ruprecht. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The purpose of this work is to provide a comprehensive atlas of the rhesus monkey brain based on state-of-the-art MRI. It offers three-dimensional coverage at high isotropic spatial resolution and with contrasts which are compatible with human MRI studies. The work further includes advanced techniques such as magnetic resonance angiography and diffusion tensor imaging which may be exploited for a visualization of the intracranial vasculature and the virtual reconstruction of nerve fiber tracts, respectively. This MRI atlas is expected to serve ... as a reference source for easy identification of anatomical structures in the rhesus monkey brain. All cross-sectional images are presented in a stereotaxic coordinate system that is defined in accordance with internal brain structures rather than outer landmarks of the head or skull. Because the atlas entirely focuses on in vivo MRI, the resolution does not reach a microscopic scale similar to histology"--Introduction, p. 9.

The Mouse Brain in Stereotaxic Coordinates: Compact Second Edition

Author : George Paxinos
Publisher : Gulf Professional Publishing
ISBN 13 : 9780125476409
Total Pages : 130 pages
Book Rating : 4.4/5 (764 download)

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Book Synopsis The Mouse Brain in Stereotaxic Coordinates: Compact Second Edition by : George Paxinos

Download or read book The Mouse Brain in Stereotaxic Coordinates: Compact Second Edition written by George Paxinos and published by Gulf Professional Publishing. This book was released on 2004 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of 'The Mouse Brain in Steroetaxic Coordinates' includes lower brainstem sections, an entire sagittal plan of section and includes a revised section on all delineations, especially of the cortex.

Atlas of the Spinal Cord

Author : Gulgun Sengul
Publisher : Academic Press
ISBN 13 : 9780123978769
Total Pages : 0 pages
Book Rating : 4.9/5 (787 download)

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Book Synopsis Atlas of the Spinal Cord by : Gulgun Sengul

Download or read book Atlas of the Spinal Cord written by Gulgun Sengul and published by Academic Press. This book was released on 2012-10-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Atlas of the Spinal Cord is the first comprehensive atlas of rodent and primate spinal cords. This atlas features histological images and labeled drawings of every segment from rat, mouse, marmoset monkey, rhesus monkey, and human spinal cords. Nissl-stained section images and matching drawings for each segment are supplemented by up to four histochemical or immunohistochemical images on a facing page. The neuron groups supplying major limb muscles are identified in each species. Constructed by the established leaders in neuroanatomical atlas development, this new atlas will be the indispensible resource for scientists who work on rodent or primate spinal cord.

A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates

Author : Kadharbatcha S. Saleem
Publisher : Elsevier
ISBN 13 : 0080467776
Total Pages : 336 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates by : Kadharbatcha S. Saleem

Download or read book A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates written by Kadharbatcha S. Saleem and published by Elsevier. This book was released on 2006-11-21 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas maps the detailed architectonic subdivisions of the cortical and subcortical areas in the macaque monkey brain using high-resolution magnetic resonance (MR) images and the corresponding histology sections in the same animal. This book presents the detailed mapping of the architectonic areas in the horizontal plane of sections with reference to the MRI that has not been reported previously in macaque monkeys. In the second part of the atlas, the coronal plane is presented using the same technique. A third part shows the quick identification of several important cortical and subcortical areas (around 30 areas) in horizontal, coronal and sagittal MR images. This atlas is unlike anything else available as it includes and compares each section to imaging data. This is a significant progress, as the vast majority of research in the field now routinely work with fMRI images. · Provides the first combined MRI and Histology maps of the cortical and subcortical areas of any non-human primate species · Shows the first detailed delineations of the cortical and subcortical areas in both horizontal and coronal planes in the same animal using five different staining methods · Illustrates the entire dorsoventral extent of the left hemisphere in 47 horizontal MRI and photomicrographs matched with 47 detailed diagrams (Chapter 3) · Presents the full rostrocaudal extent of the right hemisphere in 76 coronal MRI and photomicrographs, and 76 corresponding drawings (Chapter 4) · Illustrates the selected cortical and subcortical areas in horizontal, coronal and sagittal MRI planes (Chapter 5) · Provides the sterotaxic grid derived from the in-vivo MR image · Likely to become a standard reference for anatomical, physiological, and functional imaging studies in primates (fMRI, PET and MEG)

Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 4: Toxicologic Pathology of Organ Systems

Author : Wanda M. Haschek
Publisher : Elsevier
ISBN 13 : 032399282X
Total Pages : 910 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 4: Toxicologic Pathology of Organ Systems by : Wanda M. Haschek

Download or read book Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 4: Toxicologic Pathology of Organ Systems written by Wanda M. Haschek and published by Elsevier. This book was released on 2024-05-02 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume Four: Toxicologic Pathology of Organ Systems is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Organ systems covered include cardiac, vascular and skeletal muscle systems and the endocrine, respiratory, reproductive, digestive and nervous systems. Completely revised with a new olfactory chapter, this new release is an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Presents updated chapters on systems toxicologic pathology, including new chapter on olfactory Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full-color images in both the print and electronic versions to highlight difficult concepts with clear illustrations

The Marmoset Brain in Stereotaxic Coordinates

Author : George Paxinos
Publisher : Academic Press
ISBN 13 : 9780124158184
Total Pages : 0 pages
Book Rating : 4.1/5 (581 download)

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Book Synopsis The Marmoset Brain in Stereotaxic Coordinates by : George Paxinos

Download or read book The Marmoset Brain in Stereotaxic Coordinates written by George Paxinos and published by Academic Press. This book was released on 2011-10-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Marmoset Brain in Stereotaxic Coordinates is the most comprehensive atlas of the brain of this animal available. The atlas is constructed in the style of The Rat Brain in Stereotaxic Coordinates, the most-cited book in neuroscience. It represents a collaboration between world leaders in neuroanatomy of the primate cortex and subcortex. It will be an indispensible tool for neuroanatomists, behavioral neuroscientists, and molecular biologists trying to understand the primate brain. ENDORSED BY SOCIETY FOR BRAIN MAPPING AND THERAPEUTICS (SBMT) - SBMT is a non-profit society organized for the purpose of encouraging basic and clinical scientists who are interested in areas of Brain Mapping, engineering, stem cell, nanotechnology, imaging and medical device to improve the diagnosis, treatment and rehabilitation of patients afflicted with neurological disorders. This society promotes the public welfare and improves patient care through the translation of new technologies/therapies into life saving diagnostic and therapeutic procedures. The Society is focused in breaking boundaries of science, technology, medicine, art and healthcare policy. For more information about how to become a member or participate in SBMT programs please visit: www.WorldBrainMapping.org

Fundamental Neuropathology for Pathologists and Toxicologists

Author : Brad Bolon
Publisher : John Wiley & Sons
ISBN 13 : 1118002237
Total Pages : 661 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Fundamental Neuropathology for Pathologists and Toxicologists by : Brad Bolon

Download or read book Fundamental Neuropathology for Pathologists and Toxicologists written by Brad Bolon and published by John Wiley & Sons. This book was released on 2011-08-08 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers pathologists, toxicologists, other medical professionals, and students an introduction to the discipline and techniques of neuropathology – including chemical and environmental, biological, medical, and regulatory details important for performing an analysis of toxicant-induced neurodiseases. In addition to a section on fundamentals, the book provides detailed coverage of current practices (bioassays, molecular analysis, and nervous system pathology) and practical aspects (data interpretation, regulatory considerations, and tips for preparing reports).

Methods for Neural Ensemble Recordings, Second Edition

Author : Miguel A. L. Nicolelis
Publisher : CRC Press
ISBN 13 : 9781420006414
Total Pages : 296 pages
Book Rating : 4.0/5 (64 download)

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Book Synopsis Methods for Neural Ensemble Recordings, Second Edition by : Miguel A. L. Nicolelis

Download or read book Methods for Neural Ensemble Recordings, Second Edition written by Miguel A. L. Nicolelis and published by CRC Press. This book was released on 2007-12-03 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last ten years neural ensemble recording grew into a well-respected and highly data-lucrative science. New experimental paradigms, including the fabrication of high-density microelectrodes, new surgical implantation techniques, multi-channel signal processing, and the establishment of direct real-time brain-machine interfaces, hold promise not just for neurophysiology research, but also for new-generation prosthetic devices aimed at restoring mobility and communication skills in severely disabled patients. Extensively updated and expanded, Methods for Neural Ensemble Recording, Second Edition distills the current state-of-the-science and provides the nuts and bolts foundation from which to advance the field for the next ten years. With contributions from pioneering researchers, this second edition begins with an overview of microwire array design for chronic neural recordings. Demonstrating the diversity now enjoyed in the field, the book reviews new surgical techniques for chronic implantation of microwire arrays in not just rodents, but primates as well. It explores microelectrode microstimulation of brain tissue, discusses multielectrode recordings in the somatosensory system and during learning, and analyzes neural ensemble recordings from the central gustatory-reward pathways in awake and behaving animals. An exploration of new strategies for neural ensemble data analysis for Brain-Machine Interface (BMI) applications foreshadows an investigation into employing BMI to restore neurological function. Using multielectrode field potential recordings, contributions define global brain states and propose conceptual and technical approaches to human neural ensemble recordings in the future.

The Claustrum

Author : John R. Smythies
Publisher : Academic Press
ISBN 13 : 012404722X
Total Pages : 408 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis The Claustrum by : John R. Smythies

Download or read book The Claustrum written by John R. Smythies and published by Academic Press. This book was released on 2013-11-11 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present day is witnessing an explosion of our understanding of how the brain works at all levels, in which complexity is piled on complexity, and mechanisms of astonishing elegance are being continually discovered. This process is most developed in the major areas of the brain, such as the cortex, thalamus, and striatum. The Claustrum instead focuses on a small, remote, and, until recently, relatively unknown area of the brain. In recent years, researchers have come to believe that the claustrum is concerned with consciousness, a bold hypothesis supported by the claustrum’s two-way connections with nearly every other region of the brain and its seeming involvement with multisensory integrations—the hallmark of consciousness. The claustrum, previously in a humble position at the back of the stage, might in fact be the conductor of the brain’s orchestra. The Claustrum brings together leading experts on the claustrum from the varied disciplines of neuroscience, providing a state-of-the-art presentation of what is currently known about the claustrum, promising lines of current research (including epigenetics), and projections of new lines of investigation on the horizon. Develops a unifying hypothesis about the claustrum’s role in consciousness, as well as the integration of sensory information and other higher brain functions. Discusses the involvement of the claustrum with autism, schizophrenia, epilepsy, Alzheimer’s disease, and Parkinson’s disease Coverage of all aspects of the claustrum, from its evolution and development to promising new lines of research, including epigenetics, provides a platform and point of reference for future investigative efforts

Neuroprosthetics

Author : Justin C. Sanchez
Publisher : CRC Press
ISBN 13 : 1466553243
Total Pages : 236 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Neuroprosthetics by : Justin C. Sanchez

Download or read book Neuroprosthetics written by Justin C. Sanchez and published by CRC Press. This book was released on 2018-09-03 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master the tools of design thinking using Neuroprosthetics: Principles and Applications. Developed from successfully tested material used in an undergraduate and graduate level course taught to biomedical engineering and neuroscience students, this book focuses on the use of direct neural sensing and stimulation as a therapeutic intervention for complex disorders of the brain. It covers the theory and applications behind neuroprosthetics and explores how neuroprosthetic design thinking can enhance value for users of a direct neural interface. The book explains the fundamentals of design thinking, introduces essential concepts from neuroscience and engineering illustrating the major components of neuroprosthetics, and presents practical applications. In addition to describing the approach of design thinking (based on facts about the user’s needs, desires, habits, attitudes, and experiences with neuroprosthetics), it also examines how effectively "human centered" neuroprosthetics can address people’s needs and interactions in their daily lives. Identifying concepts and features of devices that work well with users of a direct neural interface, this book: Outlines the signal sensing capabilities and trade-offs for common electrode designs, and determines the most appropriate electrode for any neuroprosthetic application Specifies neurosurgical techniques and how electronics should be tailored to capture neural signals Provides an understanding of the mechanisms of neural–electrode performance and information contained in neural signals Provides understanding of neural decoding in neuroprosthetic applications Describes the strategies that can be used to promote long-term therapeutic interventions for humans through the use of neuroprosthetics The first true primary text for undergraduate and graduate students in departments of neuroscience and bioengineering that covers the theory and applications behind this science, Neuroprosthetics: Principles and Applications provides the fundamental knowledge needed to understand how electrodes translate neural activity into signals that are useable by machines and enables readers to master the tools of design thinking and apply them to any neuroprosthetic application.

Neuraxial Therapeutics

Author : Tony Yaksh
Publisher : Springer Nature
ISBN 13 : 3031395581
Total Pages : 829 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Neuraxial Therapeutics by : Tony Yaksh

Download or read book Neuraxial Therapeutics written by Tony Yaksh and published by Springer Nature. This book was released on 2024-01-02 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive reference of the neuraxial route for the delivery of therapeutics. It reviews the historical evolution of this approach from its inception in the later 1800's to present day. This amply referenced text covers basic discussions of spinal anatomy, embryogenesis, neuraxial vascularity, cerebrospinal fluid flow dynamics and parenchymal molecule movement. The pharmacokinetic and pharmacodynamic properties of different intrathecal agents are explored in detail with particular reference to clinical correlates in pain and spasticity. Particular attention is paid to the issues relevant to preclinical models of intrathecal delivery and the assessment of spinal pathologies arising from acute and chronic intrathecal drug delivery. Chapters provide essential discussions of clinical aspects of patient care, including patient evaluation and screening, trialing and device management, troubleshooting problems and addressing complications, best practices, cost-effectiveness and future of the therapy. Clinicians and researchers who practice intrathecal therapy and study neuraxial mechanisms will find Neuraxial Therapeutics, to be an invaluable guide to this treatment modality.

Recent Developments in Neuroanatomical Terminology

Author : Hans J. ten Donkelaar
Publisher : Frontiers Media SA
ISBN 13 : 2889631265
Total Pages : 220 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Recent Developments in Neuroanatomical Terminology by : Hans J. ten Donkelaar

Download or read book Recent Developments in Neuroanatomical Terminology written by Hans J. ten Donkelaar and published by Frontiers Media SA. This book was released on 2019-11-01 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present series of papers are meant to provoke discussion on neuroanatomical terminology. After publication of the Terminologia Neuroanatomica (TNA 2017; http://FIPAT.library.dal.ca) and its recent ratification by the International Federation of Associations of Anatomists (IFAA), August 9 in London (UK), several neuroscientists were invited to give their views on this new official IFAA terminology. This resulted in 12 papers and one commentary on the following topics: (A) Further development of a developmental ontology; (B) Common terminology for cerebral cortex and thalamus; (C) White matter tracts; and (D) Neuron types. The suggestions made to improve the TNA will be considered in the next version of the TNA. Neuroanatomical terminology should remain an actively ongoing endeavor and concerns all using this nomenclature, whether in Latin, English or other languages.

The Rat Brain in Stereotaxic Coordinates

Author : George Paxinos
Publisher : Academic Press
ISBN 13 : 9780123919496
Total Pages : 0 pages
Book Rating : 4.9/5 (194 download)

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Book Synopsis The Rat Brain in Stereotaxic Coordinates by : George Paxinos

Download or read book The Rat Brain in Stereotaxic Coordinates written by George Paxinos and published by Academic Press. This book was released on 2013-10-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its first edition in 1982, the Paxinos and Watson rat brain atlas has become the most trusted source of accurate coordinates and anatomical information in laboratories throughout the world. It has been cited over 60,000 times, making it the most cited publication in neuroscience. The seventh edition incorporates new findings on developmental gene expression and presents the boundaries of neuromeres in sagittal sections.

Magnetic Resonance Scanning and Epilepsy

Author : Simon D. Shorvon
Publisher : Springer Science & Business Media
ISBN 13 : 1461525462
Total Pages : 297 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Magnetic Resonance Scanning and Epilepsy by : Simon D. Shorvon

Download or read book Magnetic Resonance Scanning and Epilepsy written by Simon D. Shorvon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: It was only in 1980 that the first recognisable magnetic resonance images of the human brain were published, by Moore and Holland from Nottingham University in England. There then followed a number of clinical trials of brain imaging, the most notable from the Hammersmith Hospital in London using a system designed by EMI, the original manufacturers of the first CT machines. A true revolution in medicine has ensued; in only a few years there are thousands of scanning units, and magnetic resonance imaging (MRI) has assumed a central importance in medical investigation. It is an extraordinary fact that within a few years of development, the esoteric physics of nuclear spin, angular momentum, and magnetic vector precession were harnessed to provide exquisite images of living anatomy; modem science has no greater tribute. That indisputable king of neurology and the oldest of recorded conditions, epilepsy, has not been untouched by the new technology; indeed, it is our view that the introduction of MRI of electroencephalography (EEG) in the late has been as important to epilepsy as was that 1930s. Now, for the first time, the structural and aetiological basis of the condition is susceptible to thorough investigation, and MRI can provide structural detail to parallel the functional detail of EEG. MRI has the same potential as had EEG over 50 years ago, to provide a new level of understanding of the basic mechanisms, the clinical features and the treatment of epilepsy.