The Prefrontal Cortex As An Executive Emotional And Social Brain

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The Prefrontal Cortex as an Executive, Emotional, and Social Brain

Author : Masataka Watanabe
Publisher : Springer
ISBN 13 : 4431565086
Total Pages : 276 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis The Prefrontal Cortex as an Executive, Emotional, and Social Brain by : Masataka Watanabe

Download or read book The Prefrontal Cortex as an Executive, Emotional, and Social Brain written by Masataka Watanabe and published by Springer. This book was released on 2017-02-22 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to the executive, emotional, social, and integrative functions of the prefrontal cortex (PFC). The PFC has usually been studied only with its executive function or with its emotional function, but recent studies indicate that the PFC plays important roles in integrating executive and emotional functions as well as in social behavior. The first part of the book reviews the functional organization of the PFC in human and nonhuman primates. The subsequent part focuses on the integrator of executive and emotional functions. The third part presents the integrator of executive and social functions, and the final part discusses the default mode of brain activities. There are chapters on animal studies, because functional significance of the PFC cannot be described without referring to those studies. Thus many methodologies are presented such as human neuropsychological, neuroimaging, and stimulation studies, and animal neuropsychological, neurophysiological, neurochemical, neuroanatomical, and neuroimaging studies. Bringing those together, this volume provides a timely and concise picture of the function of the PFC. The result is a valuable resource for students and scientists, providing up-to-date information on this emerging research topic.

The Prefrontal Cortex

Author : Joaquin M. Fuster
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 364 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Prefrontal Cortex by : Joaquin M. Fuster

Download or read book The Prefrontal Cortex written by Joaquin M. Fuster and published by Lippincott Williams & Wilkins. This book was released on 1997 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Prefrontal Cortex

Author : Ana Starcevic
Publisher : BoD – Books on Demand
ISBN 13 : 1789239036
Total Pages : 134 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Prefrontal Cortex by : Ana Starcevic

Download or read book Prefrontal Cortex written by Ana Starcevic and published by BoD – Books on Demand. This book was released on 2018-10-03 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prefrontal cortex reaches its greatest development in the human brain, making up nearly one third of the neocortex. Due to its remarkable evolution, the prefrontal cortex plays an important role in higher integrative functions such as information processing, thinking, understanding, attention, behavior, motivation, emotions, working memory, and analysis. This book brings together theoretical and technical research advances on the prefrontal cortex, from the basic explanations of the neuronal architecture of the prefrontal cortex and its anatomy, presenting it as a morphological substrate for many psychological conditions, through normal and altered connectivity and its manifestation in different behavior and identification of organizational levels inside the prefrontal cortex through different neuroimaging methods. It also provides an interdisciplinary view of the prefrontal cortex and its issues and discovers the main role of this part of brain in psychosocial, economic, and cultural adaptation.

The Prefrontal Cortex

Author : Joaquin Fuster
Publisher : Academic Press
ISBN 13 : 012408060X
Total Pages : 461 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis The Prefrontal Cortex by : Joaquin Fuster

Download or read book The Prefrontal Cortex written by Joaquin Fuster and published by Academic Press. This book was released on 2015-05-22 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Prefrontal Cortex, Fifth Edition, provides users with a thoroughly updated version of this comprehensive work that has historically served as the classic reference on this part of the brain. The book offers a unifying, interdisciplinary perspective that is lacking in other volumes written about the frontal lobes, and is, once again, written by the award-winning author who discovered "memory cells," the physiological substrate of working memory. The fifth edition constitutes a comprehensive update, including all the major advances made on the physiology and cognitive neuroscience of the region since publication in 2008. All chapters have been fully revised, and the overview of prefrontal functions now interprets experimental data within the theoretical framework of the new paradigm of cortical structure and dynamics (the Cognit Paradigm), addressing the accompanying social, economic, and cultural implications. Provides a distinctly interdisciplinary view of the prefrontal cortex, covering all major methodologies, from comparative anatomy to modern imaging Unique analysis and synthesis of a large body of basic and clinical data on the subject (more than 2000 references) Written by an award-winning author who discovered "memory cells," the physiological substrate of working memory Synthesizes evidence that the prefrontal cortex constitutes a complex pre-adaptive system Incorporates emerging study of the role of the frontal lobes in social, economic, and cultural adaptation

The New Executive Brain

Author : Elkhonon Goldberg
Publisher : Oxford University Press
ISBN 13 : 0199758506
Total Pages : 353 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis The New Executive Brain by : Elkhonon Goldberg

Download or read book The New Executive Brain written by Elkhonon Goldberg and published by Oxford University Press. This book was released on 2009-08-12 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Elkhonon Goldberg's groundbreaking The Executive Brain was a classic of scientific writing, revealing how the frontal lobes command the most human parts of the mind. Now he offers a completely new book, providing fresh, iconoclastic ideas about the relationship between the brain and the mind. In The New Executive Brain, Goldberg paints a sweeping panorama of cutting-edge thinking in cognitive neuroscience and neuropsychology, one that ranges far beyond the frontal lobes. Drawing on the latest discoveries, and developing complex scientific ideas and relating them to real life through many fascinating case studies and anecdotes, the author explores how the brain engages in complex decision-making; how it deals with novelty and ambiguity; and how it addresses moral choices. At every step, Goldberg challenges entrenched assumptions. For example, we know that the left hemisphere of the brain is the seat of language--but Goldberg argues that language may not be the central adaptation of the left hemisphere. Apes lack language, yet many also show evidence of asymmetric hemispheric development. Goldberg also finds that a complex interaction between the frontal lobes and the amygdale--between a recently evolved and a much older part of the brain--controls emotion, as conscious thoughts meet automatic impulses. The author illustrates this observation with a personal example: the difficulty he experienced when trying to pick up a baby alligator he knew to be harmless, as his amygdala battled his effort to extend his hand. In the years since the original Executive Brain, Goldberg has remained at the front of his field, constantly challenging orthodoxy. In this revised and expanded edition, he affirms his place as one of our most creative and insightful scientists, offering lucid writing and bold, paradigm-shifting ideas.

What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology

Author :
Publisher : Academic Press
ISBN 13 : 0323853374
Total Pages : 490 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology by :

Download or read book What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology written by and published by Academic Press. This book was released on 2021-03-28 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: What does Medial Frontal Cortex Signal During Behavior? Insights from Behavioral Neurophysiology, Volume 158 addresses and highlights a question that has remained central to cognitive and systems neuroscience since its inception, namely, what does the medial frontal cortex do? With insights from 17 of the fields leading teams of scientists, this volume attempts to address this question covering several topics with chapters including What do single unit responses in dorsal anterior cingulate cortex mean?, Social Processing by the Primate Medial Frontal Cortex, Medial frontal cortex and the temporal control of action, The midcingulate cortex and temporal integration, and more. Additional chapters cover The anterior cingulate cortex and event-based modulation of autonomic states, Integration of value and action in medial prefrontal neural systems, Secondary motor cortex: broadcasting and biasing animal’s decisions through long-range circuits, The prefrontal cortex in social cognition, Representing task strategies in the medial prefrontal cortex, Prefrontal contributions to action control in rodents, From affective to cognitive processings: functional organization of the medial frontal cortex, and much more. Comprises the perspectives of a diverse array of world-leading researchers in medial frontal cortex function Provides the latest theoretical and data-based evidence for the function of medial frontal cortex Presents the importance of systems-based neuroscience approaches to the understanding of medial frontal cortex function

The Infant Mind

Author : Maria Legerstee
Publisher : Guilford Press
ISBN 13 : 1462508170
Total Pages : 385 pages
Book Rating : 4.4/5 (625 download)

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Book Synopsis The Infant Mind by : Maria Legerstee

Download or read book The Infant Mind written by Maria Legerstee and published by Guilford Press. This book was released on 2013-01-22 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrating cutting-edge research from multiple disciplines, this book provides a dynamic and holistic picture of the developing infant mind. Contributors explore the transactions among genes, the brain, and the environment in the earliest years of life. The volume probes the neural correlates of core sensory, perceptual, cognitive, emotional, and social capacities. It highlights the importance of early relationships, presenting compelling findings on how parent-infant interactions influence neural processing and brain maturation. Innovative research methods are discussed, including applications of behavioral, hormonal, genetic, and brain imaging technologies.

Principles of Frontal Lobe Function

Author : Donald T. Stuss
Publisher : Oxford University Press, USA
ISBN 13 : 0199837759
Total Pages : 799 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Principles of Frontal Lobe Function by : Donald T. Stuss

Download or read book Principles of Frontal Lobe Function written by Donald T. Stuss and published by Oxford University Press, USA. This book was released on 2013-01-31 with total page 799 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Frontal Lobe Function, Second Edition is an expanded volume, divided into 9 sections representing major research and clinical disciples, including new topics such as social neuroscience. This book will provide clinicians, researchers, and students with the most current information as the mystery of the frontal lobes is unraveled.

The Little Black Book of Neuropsychology

Author : Mike R. Schoenberg
Publisher : Springer Science & Business Media
ISBN 13 : 0387769781
Total Pages : 974 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis The Little Black Book of Neuropsychology by : Mike R. Schoenberg

Download or read book The Little Black Book of Neuropsychology written by Mike R. Schoenberg and published by Springer Science & Business Media. This book was released on 2011-01-11 with total page 974 pages. Available in PDF, EPUB and Kindle. Book excerpt: From translating the patient’s medical records and test results to providing recommendations, the neuropsychological evaluation incorporates the science and practice of neuropsychology, neurology, and psychological sciences. The Little Black Book of Neuropsychology brings the practice and study of neuropsychology into concise step-by-step focus—without skimping on scientific quality. This one-of-a-kind assessment reference complements standard textbooks by outlining signs, symptoms, and complaints according to neuropsychological domain (such as memory, language, or executive function), with descriptions of possible deficits involved, inpatient and outpatient assessment methods, and possible etiologies. Additional chapters offer a more traditional approach to evaluation, discussing specific neurological disorders and diseases in terms of their clinical features, neuroanatomical correlates, and assessment and treatment considerations. Chapters in psychometrics provide for initial understanding of brain-behavior interpretation as well as more advanced principals for neuropsychology practice including new diagnostic concepts and analysis of change in performance over time. For the trainee, beginning clinician or seasoned expert, this user-friendly presentation incorporating ‘quick reference guides’ throughout which will add to the practice armentarium of beginning and seasoned clinicians alike. Key features of The Black Book of Neuropsychology: Concise framework for understanding the neuropsychological referral. Symptoms/syndromes presented in a handy outline format, with dozens of charts and tables. Review of basic neurobehavioral examination procedure. Attention to professional issues, including advances in psychometrics and diagnoses, including tables for reliable change for many commonly used tests. Special “Writing Reports like You Mean It” section and guidelines for answering referral questions. Includes appendices of practical information, including neuropsychological formulary. The Little Black Book of Neuropsychology is an indispensable resource for the range of practitioners and scientists interested in brain-behavior relationships. Particular emphasis is provided for trainees in neuropsychology and neuropsychologists. However, the easy to use format and concise presentation is likely to be of particular value to interns, residents, and fellows studying neurology, neurological surgery, psychiatry, and nurses. Finally, teachers of neuropsychological and neurological assessment may also find this book useful as a classroom text. "There is no other book in the field that covers the scope of material that is inside this comprehensive text. The work might be best summed up as being a clinical neuropsychology postdoctoral residency in a book, with the most up to date information available, so that it is also an indispensible book for practicing neuropsychologists in addition to students and residents...There is really no book like this available today. It skillfully brings together the most important foundationsof clinical neuropsychology with the 'nuts and bolts' of every facet of assessment. It also reminds the more weathered neuropsychologists among us of the essential value of neuropsychological assessment...the impact of the disease on the patient’s cognitive functioning and behavior may only be objectively quantified through a neuropsychological assessment." Arch Clin Neuropsychol (2011) first published online June 13, 2011 Read the full review acn.oxfordjournals.org

The Wiley Handbook of Cognitive Control

Author : Tobias Egner
Publisher : John Wiley & Sons
ISBN 13 : 1118920546
Total Pages : 629 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis The Wiley Handbook of Cognitive Control by : Tobias Egner

Download or read book The Wiley Handbook of Cognitive Control written by Tobias Egner and published by John Wiley & Sons. This book was released on 2017-03-20 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering basic theory, new research, and intersections with adjacent fields, this is the first comprehensive reference work on cognitive control – our ability to use internal goals to guide thought and behavior. Draws together expert perspectives from a range of disciplines, including cognitive psychology, neuropsychology, neuroscience, cognitive science, and neurology Covers behavioral phenomena of cognitive control, neuroanatomical and computational models of frontal lobe function, and the interface between cognitive control and other mental processes Explores the ways in which cognitive control research can inform and enhance our understanding of brain development and neurological and psychiatric conditions

The Neuroscience of Emotion

Author : Ralph Adolphs
Publisher : Princeton University Press
ISBN 13 : 140088991X
Total Pages : 374 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis The Neuroscience of Emotion by : Ralph Adolphs

Download or read book The Neuroscience of Emotion written by Ralph Adolphs and published by Princeton University Press. This book was released on 2018-06-05 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new framework for the neuroscientific study of emotions in humans and animals The Neuroscience of Emotion presents a new framework for the neuroscientific study of emotion across species. Written by Ralph Adolphs and David J. Anderson, two leading authorities on the study of emotion, this accessible and original book recasts the discipline and demonstrates that in order to understand emotion, we need to examine its biological roots in humans and animals. Only through a comparative approach that encompasses work at the molecular, cellular, systems, and cognitive levels will we be able to comprehend what emotions do, how they evolved, how the brain shapes their development, and even how we might engineer them into robots in the future. Showing that emotions are ubiquitous across species and implemented in specific brain circuits, Adolphs and Anderson offer a broad foundation for thinking about emotions as evolved, functionally defined biological states. The authors discuss the techniques and findings from modern neuroscientific investigations of emotion and conclude with a survey of theories and future research directions. Featuring color illustrations throughout, The Neuroscience of Emotion synthesizes the latest in neuroscientific work to provide deeper insights into how emotions function in all of us.

The Social Brain

Author : Jean Decety
Publisher : MIT Press
ISBN 13 : 0262044145
Total Pages : 441 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis The Social Brain by : Jean Decety

Download or read book The Social Brain written by Jean Decety and published by MIT Press. This book was released on 2020-08-18 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: A range of empirical and theoretical perspectives on the relationship between biology and social cognition from infancy through childhood. Recent research on the developmental origins of the social mind supports the view that social cognition is present early in infancy and childhood in surprisingly sophisticated forms. Developmental psychologists have found ingenious ways to test the social abilities of infants and young children, and neuroscientists have begun to study the neurobiological mechanisms that implement and guide early social cognition. Their work suggests that, far from being unfinished adults, babies are exquisitely designed by evolution to capture relevant social information, learn, and explore their social environments. This volume offers a range of empirical and theoretical perspectives on the relationship between biology and social cognition from infancy through childhood. The contributors consider scientific advances in early social perception and cognition, including findings on the development of face processing and social perceptual biases; explore recent research on early infant competencies for language and theory of mind, including a developmental account of how young children become moral agents and the role of electrophysiology in identifying psychological processes that underpin social cognition; discuss the origins and development of prosocial behavior, reviewing evidence for a set of innate predispositions to be social, cooperative, and altruistic; examine how young children make social categories; and analyze atypical social cognition, including autism spectrum disorder and psychopathy. Contributors Lior Abramson, Renée Baillargeon, Pascal Belin, Frances Buttelmann, Sofia Cardenas, Michael J. Crowley, Fabrice Damon, Jean Decety, Michelle de Haan, Ghislaine Dehaene-Lambertz, Melody Buyukozer Dawkins, Xiao Pan Ding, Kristen A. Dunfield, Rachel D. Fine, Ana Fló, Jennifer R. Frey, Susan A. Gelman, Diane Goldenberg, Marie-Hélène Grosbras, Tobias Grossmann, Caitlin M. Hudac, Dora Kampis, Tara A. Karasewich, Ariel Knafo-Noam, Tehila Kogut, Ágnes Melinda Kovács, Valerie A. Kuhlmeier, Kang Lee, Narcis Marshall, Eamon McCrory, David Méary, Christos Panagiotopoulos, Olivier Pascalis, Markus Paulus, Kevin A. Pelphrey, Marcela Peña, Valerie F. Reyna, Marjorie Rhodes, Ruth Roberts, Hagit Sabato, Darby Saxbe, Virginia Slaughter, Jessica A. Sommerville, Maayan Stavans, Nikolaus Steinbeis, Fransisca Ting, Florina Uzefovsky, Essi Viding

The Orbitofrontal Cortex

Author : Edmund Rolls
Publisher : Oxford University Press, USA
ISBN 13 : 0198845995
Total Pages : 318 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis The Orbitofrontal Cortex by : Edmund Rolls

Download or read book The Orbitofrontal Cortex written by Edmund Rolls and published by Oxford University Press, USA. This book was released on 2019 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'The Orbitofrontal Cortex' explores a part of the brain that is important in human emotion, pleasure, decision-making, valuation, and personality. The book is unique in providing a coherent multidisciplinary approach to understanding the functions of one of the most interesting regions of the human brain, in both health and in disease.

Emotion and Reason

Author : Warren D. TenHouten
Publisher : Routledge
ISBN 13 : 1317580605
Total Pages : 383 pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis Emotion and Reason by : Warren D. TenHouten

Download or read book Emotion and Reason written by Warren D. TenHouten and published by Routledge. This book was released on 2014-06-23 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although much academic work has been done on the areas of mind, brain, and society, a theoretical synthesis of the three levels of analysis – the biological, the mental, and the social – has not until now been put forward. In Emotion and Reason, Warren TenHouten presents a truly comprehensive classification of the emotions. The book analyzes six key emotions: anger, acceptance, aggressiveness, love, joy and happiness, and anticipation. It places them in historical context, relates them to situations of work and intimacy, and explains their functioning within an individuated, autonomous character structure. Divided into four parts, the book presents a socioevolutionary theory of the emotions – Affect-spectrum Theory (AST), which is based on a synthesis of three models, of the emotions, of social relationships, and of cognition. This book will be of value to undergraduate and postgraduate students, as well as researchers, with an interest in the sociology of emotions, anthropology of emotions, social psychology, affective neuroscience, political science, behavioral neuroeconomics and philosophy.

The Cognitive Neuroscience of Mind

Author : Michael S. Gazzaniga
Publisher : MIT Press
ISBN 13 : 0262014017
Total Pages : 259 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis The Cognitive Neuroscience of Mind by : Michael S. Gazzaniga

Download or read book The Cognitive Neuroscience of Mind written by Michael S. Gazzaniga and published by MIT Press. This book was released on 2010 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: These essays on a range of topics in the cognitive neurosciences report on the progress in the field over the twenty years of its existence and reflect the many groundbreaking scientific contributions and enduring influence of Michael Gazzaniga, 'the godfather of cognitive neuroscience'.

Impulsivity and Compulsivity

Author : John M. Oldham
Publisher : American Psychiatric Pub
ISBN 13 : 9780880486767
Total Pages : 314 pages
Book Rating : 4.4/5 (867 download)

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Book Synopsis Impulsivity and Compulsivity by : John M. Oldham

Download or read book Impulsivity and Compulsivity written by John M. Oldham and published by American Psychiatric Pub. This book was released on 1996 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, impulsive and compulsive behaviors have been categorized as fundamentally distinct. However, patients often exhibit both of these behaviors. This common comorbidity has sparked renewed interest in the factors contributing to the disorders in which these behaviors are prominent. Impulsivity and Compulsivity applies a provocative spectrum model to this psychopathology. The spectrum model is consistent with a dimensional model for psychopathology and considers the dynamic interaction of biopsychosocial forces in the development of impulsive and compulsive disorders. In this important work on impulsive/compulsive psychopathology, leading researchers and clinicians share their expertise on the phenomenological, biological, psychodynamic, and treatment aspects of these disorders. Differential diagnosis, comorbidity of the impulsive-compulsive spectrum of disorders, and assessment by the seven-factor model of temperament and character are discussed. Chapters are also dedicated to the antianxiety function of impulsivity and compulsivity, defense mechanisms in impulsive disorders versus obsessive-compulsive disorders, and the unique aspects of psychotherapy with impulsive and compulsive patients. Clinical researchers and clinicians will be enlightened by this exceptional work. The information provided is supplemented with clinical vignettes, and the final chapter provides a synthetic summary that offers a unified, dynamic approach to impulsive and compulsive behavior.

The Frontal Lobes and Neuropsychiatric Illness

Author : Stephen P. Salloway
Publisher : American Psychiatric Pub
ISBN 13 : 1585628034
Total Pages : 275 pages
Book Rating : 4.5/5 (856 download)

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Book Synopsis The Frontal Lobes and Neuropsychiatric Illness by : Stephen P. Salloway

Download or read book The Frontal Lobes and Neuropsychiatric Illness written by Stephen P. Salloway and published by American Psychiatric Pub. This book was released on 2008-11-01 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: This exciting volume brings together the latest work of 26 recognized experts in clinical neuropsychiatry, neuropsychology, neuroscience, and neuroimaging. Its chapters are organized into sections that cover a broad range of topics related to advances in our understanding of normal and abnormal frontal lobe functions. Part 1 introduces frontal lobe dysfunction as a common pathway leading to social and occupational disability, arguing that our aging population with its decline in executive cognitive abilities mandates corresponding eligibility and treatment changes in public and private health disability policies. Part 2 delineates the anatomy and neurochemistry of the extended frontal systems underlying neuropsychiatric illness, including colorful illustrations of three key prefrontal-subcortical circuits; a description of the functional anatomy of the orbitofrontal cortex and its relationship to obsessive-compulsive disorder (OCD); the intricate pharmacology of working memory systems and how they apply to schizophrenia; the lateralization of prefrontal cognitive functions; and a framework for understanding the role played by the prefrontal cortex in consciousness and self-awareness. Part 3 clarifies the overused diagnosis "frontal lobe syndrome" seen in clinical practice, identifying three prefrontal syndromes for further study -- dorsolateral dysexecutive syndrome, orbitofrontal disinhibited syndrome, and mesial frontal apathetic syndrome -- that align with the anatomical systems described in Part 2 of this volume. Also included are common problems -- and suggested solutions -- in diagnosis and treatment, a practical overview of the assessment of frontal lobe functions with guidelines for bedside and formal neuropsychological examination, and comprehensive treatment strategies. Part 4 covers the role of the frontal lobes in major neuropsychiatric illnesses, discussing evidence that shows prefrontal and anterior temporal hypometabolism in primary and secondary depression; reviewing anatomical, imaging, and neurochemical studies in schizophrenia; describing the neuropsychological and neuropsychiatric sequelae of closed head injury; summarizing the neurological substrates related to interesting and often dramatic cases of content-specific delusions; and concluding with a report on the stereotactic neurosurgical treatment of refractory OCD and its implications for understanding frontal lobe function. This remarkable work is intended for psychiatrists, neurologists, psychologists, basic and clinical neuroscientists, and trainees from each of these disciplines, who will welcome it as a valuable tool in understanding the complexities of what was once considered the terra incognita of the brain.