The Nude Mouse in Oncology Research

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Author :
Publisher : CRC Press
ISBN 13 : 1351085662
Total Pages : 350 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis The Nude Mouse in Oncology Research by : Epie Boven

Download or read book The Nude Mouse in Oncology Research written by Epie Boven and published by CRC Press. This book was released on 2018-01-18 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nude, athymic mouse (nu/nu) has become generally accepted as a valuable tool to study the biology and therapy of human cancers. This volume presents a critical review of the scientific merits of the animal as a recipient of human tumor tissue transplants. Important information is provided regarding biology, immunology, and measures for genetic and microbiological control of the nude mouse. The discussion of transplantation sites and transplantability of human tumor tissue to the animals includes both the description of host factors and the tumor type involved. The characterization and monitoring of xenografts is followed by a review on their possible application for studies in tumor biology, such as hormones, growth factors, drug resistance, tumor markers, and heterogeneity. Experimental therapy is dedicated to cytostatic agents, hormones, monoclonal antibodies, cytokines, differentiation inducers and radiotherapy. The book also provides critical remarks regarding the limitation of the nude-mouse tumor models. The Nude Mouse in Oncology Research will provide essential reference information for oncology researchers, researchers who work with the nude mouse on a regular basis, and pharmaceutical companies.

The Nude Mouse in Oncology Research

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Author :
Publisher : CRC Press
ISBN 13 : 9780849365317
Total Pages : 352 pages
Book Rating : 4.3/5 (653 download)

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Book Synopsis The Nude Mouse in Oncology Research by : Epie Boven

Download or read book The Nude Mouse in Oncology Research written by Epie Boven and published by CRC Press. This book was released on 1991-10-07 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nude, athymic mouse (nu/nu) has become generally accepted as a valuable tool to study the biology and therapy of human cancers. This volume presents a critical review of the scientific merits of the animal as a recipient of human tumor tissue transplants. Important information is provided regarding biology, immunology, and measures for genetic and microbiological control of the nude mouse. The discussion of transplantation sites and transplantability of human tumor tissue to the animals includes both the description of host factors and the tumor type involved. The characterization and monitoring of xenografts is followed by a review on their possible application for studies in tumor biology, such as hormones, growth factors, drug resistance, tumor markers, and heterogeneity. Experimental therapy is dedicated to cytostatic agents, hormones, monoclonal antibodies, cytokines, differentiation inducers and radiotherapy. The book also provides critical remarks regarding the limitation of the nude-mouse tumor models. The Nude Mouse in Oncology Research will provide essential reference information for oncology researchers, researchers who work with the nude mouse on a regular basis, and pharmaceutical companies.

The Nude Mouse in Experimental and Clinical Research

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Author :
Publisher : Elsevier
ISBN 13 : 0323147348
Total Pages : 518 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis The Nude Mouse in Experimental and Clinical Research by : Jorgen Fogh

Download or read book The Nude Mouse in Experimental and Clinical Research written by Jorgen Fogh and published by Elsevier. This book was released on 2014-01-01 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nude Mouse in Experimental and Clinical Research presents the state of knowledge regarding the nude mouse and its applications to different branches of scientific research. The research studies featured in this book emphasize the academic status of a broad range of subjects and techniques of nude mouse research. The text consists of 21 chapters, each discussing an important aspect of nude mouse research. Some chapters discuss the biological aspect such as physiology, genes, and breeding and mass production of the mouse. A number of the chapters also discuss the general observations of the mouse like histopathological observations and their background. The applications of the nude mouse to human tumor and cancer cell research are likewise given emphasis. This book will be of valuable importance to both students and researchers in the fields of medicine, biology, and pathology.

The Nude Mouse in Experimental and Clinical Research

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Publisher :
ISBN 13 :
Total Pages : 616 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Nude Mouse in Experimental and Clinical Research by : Jørgen Fogh

Download or read book The Nude Mouse in Experimental and Clinical Research written by Jørgen Fogh and published by . This book was released on 1978 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Proceedings of the Symposium on the Use of Athymic (Nude) Mice in Cancer Research, Battelle Memorial Institute, Columbus, Ohio, June 15-16, 1977

Download Proceedings of the Symposium on the Use of Athymic (Nude) Mice in Cancer Research, Battelle Memorial Institute, Columbus, Ohio, June 15-16, 1977 PDF Online Free

Author :
Publisher : Fischer Gustav Verlag GmbH & Company KG
ISBN 13 :
Total Pages : 326 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Proceedings of the Symposium on the Use of Athymic (Nude) Mice in Cancer Research, Battelle Memorial Institute, Columbus, Ohio, June 15-16, 1977 by : David P. Houchens

Download or read book Proceedings of the Symposium on the Use of Athymic (Nude) Mice in Cancer Research, Battelle Memorial Institute, Columbus, Ohio, June 15-16, 1977 written by David P. Houchens and published by Fischer Gustav Verlag GmbH & Company KG. This book was released on 1978 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunodeficient Mice in Oncology

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Author :
Publisher :
ISBN 13 :
Total Pages : 608 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immunodeficient Mice in Oncology by : H. H. Fiebig

Download or read book Immunodeficient Mice in Oncology written by H. H. Fiebig and published by . This book was released on 1992 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Patient-Derived Mouse Models of Cancer

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Author :
Publisher : Humana
ISBN 13 : 9783319861586
Total Pages : 0 pages
Book Rating : 4.8/5 (615 download)

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Book Synopsis Patient-Derived Mouse Models of Cancer by : Robert M. Hoffman

Download or read book Patient-Derived Mouse Models of Cancer written by Robert M. Hoffman and published by Humana. This book was released on 2018-06-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text highlights seminal discoveries and also provides comprehensive and state-of the-art approach to mouse models of human patient tumors. These areas include training, basic techniques, as well as general troubleshooting. Subsequent chapters focus on the different mouse models of patient tumors including the various strains of immunodeficient mice currently available and the transplantation techniques that can be used as well as state-of-the-art imaging techniques. Practical applications of the models from drug discovery, genome analysis to personalized treatment are also covered. Written by experts in that field, each of these sections address these critical issues. A brief review of the existing literature addressing the particular topic follows in each section. Presently, there is no single source to provide information on technique and uses of mouse models of human patient tumors. Patient-Derived Mouse Models of Cancer will satisfy this need for cancer researchers, oncologists, pharmaceutical and biotechnology industry scientists as well as molecular biologists studying in vivo systems

Immunodeficient Animals for Cancer Research

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Author :
Publisher : Springer
ISBN 13 : 1349050148
Total Pages : 245 pages
Book Rating : 4.3/5 (49 download)

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Book Synopsis Immunodeficient Animals for Cancer Research by : S. Sparrow

Download or read book Immunodeficient Animals for Cancer Research written by S. Sparrow and published by Springer. This book was released on 1980-06-18 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Thymusaplastic nude Mice and rats in clinical oncology

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Author :
Publisher :
ISBN 13 : 9780895741547
Total Pages : pages
Book Rating : 4.7/5 (415 download)

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Book Synopsis Thymusaplastic nude Mice and rats in clinical oncology by : Mice

Download or read book Thymusaplastic nude Mice and rats in clinical oncology written by Mice and published by . This book was released on 1981 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunodeficient Animals

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Author :
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 252 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immunodeficient Animals by : Wolfgang Arnold

Download or read book Immunodeficient Animals written by Wolfgang Arnold and published by S. Karger AG (Switzerland). This book was released on 1996 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The classic immunodeficient mutants nude, scid and rnu have an important function in experimental cancer research: they allow unique methods of investigation and provide data of clinical relevance. This volume presents the state of the art of research work based on the use of these immunodeficient animal models. One section is dedicated to the biological aspects and immunological properties of immunodeficient mutants. Another part includes articles on xenogenous transplantation of human tumors, focusing on the establishment of transplantable lines, growth characteristics and tumor markers. Special attention is given to new approaches in the fields of chemotherapy, radiation therapy and immunotherapy. Various contributors consider in vitro methods as alternative models. In addition to current data, this publication contains useful technical and methodological information and is therefore valuable not only for specialists but also for scientists entering the field of experimental cancer research.

Thymusaplastic Nude Mice and Rats in Clinical Oncology

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Author :
Publisher :
ISBN 13 : 9780895741547
Total Pages : 556 pages
Book Rating : 4.7/5 (415 download)

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Book Synopsis Thymusaplastic Nude Mice and Rats in Clinical Oncology by : Gunther B. Bastert

Download or read book Thymusaplastic Nude Mice and Rats in Clinical Oncology written by Gunther B. Bastert and published by . This book was released on 1981 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bibliography of the Nude Mouse

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Author :
Publisher :
ISBN 13 :
Total Pages : 52 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Bibliography of the Nude Mouse by : Jørgen Rygaard

Download or read book Bibliography of the Nude Mouse written by Jørgen Rygaard and published by . This book was released on 1977 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: 443 numbered references to literature (mostly journal articles). "Bibliography is based on the questionnaire sent out by the Nude Mouse Secretariat in the autumn of 1975. To this is added references collected elsewhere." Alphabetical arrangement by primary authors. Entries include bibliographical information. Subject index.

IMMUNOLOGY OF NUDE MICE

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Author :
Publisher : Springer
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis IMMUNOLOGY OF NUDE MICE by : Miroslav Holub

Download or read book IMMUNOLOGY OF NUDE MICE written by Miroslav Holub and published by Springer. This book was released on 1989-04-30 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology of Nude Mice presents a discussion of the nature of this viable laboratory mutant. This new volume updates all immunological information contained in the sparse literature concerning nude mice. It comprehensively explores some of the fre-quent questions associated with nude mice, such as if the mutant is really athymic or if the thymic defect causes all of the other deviations from brain to gonads. The practical consequences of hairlessness of the mutant are also consid-ered. Illustrated with original photographs and tables doc-umenting novel facts in immunology and physiology of nude mice, this publication is valuable for investigators and stu-dents entering the field.

Tumor Models in Cancer Research

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1607619687
Total Pages : 682 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Tumor Models in Cancer Research by : Beverly A. Teicher

Download or read book Tumor Models in Cancer Research written by Beverly A. Teicher and published by Springer Science & Business Media. This book was released on 2010-12-01 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past 6 years since the first edition of this book have seen great progress in the development of genetically engineered mouse (GEM) models of cancer. These models are finding an important role in furthering our understanding of the biology of malignant disease. A comfortable position for GEM models in the routine conduct of screening for potential new therapeutics is coming more slowly but is coming. Increasing numbers of genetically engineered mice are available, some with conditional activation of oncogenes, some with multiple genetic changes providing mouse models that are moving closer to the human disease.

Patient Derived Tumor Xenograft Models

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Author :
Publisher : Academic Press
ISBN 13 : 0128040610
Total Pages : 486 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Patient Derived Tumor Xenograft Models by : Rajesh Uthamanthil

Download or read book Patient Derived Tumor Xenograft Models written by Rajesh Uthamanthil and published by Academic Press. This book was released on 2016-10-13 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory. Offers guidance on data interpretation and regulatory aspects Provides useful techniques and strategies for working with PDX models Includes practical tools and potential pitfalls for best practices Compiles all knowledge of PDX models research in one resource Presents the results of first ever global survey on standards of PDX development and usage in academia and industry

Immune-deficient Animals in Biomedical Research

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Author :
Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 444 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immune-deficient Animals in Biomedical Research by : Jørgen Rygaard

Download or read book Immune-deficient Animals in Biomedical Research written by Jørgen Rygaard and published by S. Karger AG (Switzerland). This book was released on 1987 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Alternatives to Animal Testing

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Author :
Publisher : Springer
ISBN 13 : 9811324476
Total Pages : 130 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Alternatives to Animal Testing by : Hajime Kojima

Download or read book Alternatives to Animal Testing written by Hajime Kojima and published by Springer. This book was released on 2018-12-27 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.