The Genetics Of Cancer

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The Genetics of Cancer

Author : Gajanan V. Sherbet
Publisher : Academic Press
ISBN 13 : 9780080542485
Total Pages : 338 pages
Book Rating : 4.5/5 (424 download)

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Book Synopsis The Genetics of Cancer by : Gajanan V. Sherbet

Download or read book The Genetics of Cancer written by Gajanan V. Sherbet and published by Academic Press. This book was released on 1997-06-22 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by internationally recognized experts, The Genetics of Cancer provides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression of cancer. The Genetics of Cancer will be useful to all graduate students, clinicians, and researchers working in the fields of cancer biology, genetics, and molecular biology. Clonal evolution of the metastasis phenotype Cell Cycle regulation Apoptosis in tumour growth and metastasis Angiogenesis in cancer Cell surface glycoproteins and their receptors Proteinases and their inhibitors in cancer invasion Oncogenes and cancer metastasis Developmental genes Tumour suppressor genes Metastasis suppressor genes Dominant metastasis-associated genes

The Genetics of Cancer

Author : B.A. Ponder
Publisher : Springer Science & Business Media
ISBN 13 : 9401106770
Total Pages : 222 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis The Genetics of Cancer by : B.A. Ponder

Download or read book The Genetics of Cancer written by B.A. Ponder and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Principles of Cancer Genetics

Author : Fred Bunz
Publisher : Springer
ISBN 13 : 9401774846
Total Pages : 343 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Principles of Cancer Genetics by : Fred Bunz

Download or read book Principles of Cancer Genetics written by Fred Bunz and published by Springer. This book was released on 2016-03-01 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of a widely used textbook that consolidates the basic concepts of the cancer gene theory and provides a framework for understanding the genetic basis of cancer. Particular attention is devoted to the origins of the mutations that cause cancer, and the application of evolutionary theory to explain how the cell clones that harbor cancer genes tend to expand. Focused on the altered genes and pathways that cause the growth of the most common tumors, Principles of Cancer Genetics is aimed at advanced undergraduates who have completed introductory coursework in genetics, biology and biochemistry, medical students and medical house staff. For students with a general interest in cancer, this book provides a highly accessible and readable overview. For more advanced students contemplating future study in the field of oncology and cancer research, this concise book will be useful as a primer.

Pediatric Cancer Genetics

Author : Nathaniel H. Robin
Publisher : Elsevier Health Sciences
ISBN 13 : 0323495966
Total Pages : 350 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Pediatric Cancer Genetics by : Nathaniel H. Robin

Download or read book Pediatric Cancer Genetics written by Nathaniel H. Robin and published by Elsevier Health Sciences. This book was released on 2017-08-22 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of the many key facets of pediatric cancer genetics with this concise, practical resource by Dr. Nathaniel H. Robin and Meagan Farmer, MS, CGC, MBA. Ideal for pediatric oncologists and all providers who care for children, this easy-to-read reference addresses the remarkable potential of genetic testing as well as the complexities of choosing the correct test, understanding the results, and counseling the family. Features a wealth of information on pediatric cancer genetics, including the epidemiology and biology of cancer and the genetic evaluation process and role of genetic counselors. Highlights examples of syndromes that present in childhood and increase susceptibility to cancer. Discusses the genetic evaluation process in context of the multidisciplinary care of children with cancer. Considers the ethical and legal issues of genetic testing in children and provides illustrative case examples. Consolidates today’s available information and guidance in this timely area into one convenient resource.

Understanding Genomic and Hereditary Cancer Risk

Author : Suzanne M. Mahon
Publisher :
ISBN 13 : 9781635930498
Total Pages : 0 pages
Book Rating : 4.9/5 (34 download)

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Book Synopsis Understanding Genomic and Hereditary Cancer Risk by : Suzanne M. Mahon

Download or read book Understanding Genomic and Hereditary Cancer Risk written by Suzanne M. Mahon and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Collecting a family medical history is a regular component of the nursing assessment process that often includes information on familial cancer diagnoses, and patients may fear that they or their loved ones might be at increased risk for developing cancer because of hereditary factors. Although true inherited risk for developing cancer is much less common than acquired risk for developing cancer, approximately 10% of cancer diagnoses can be attributed to inherited risk. The identification of families exhibiting hereditary cancer syndromes enables individuals at risk to engage in increased surveillance and, in some cases, risk-reducing surgery and other preventive measures, which ultimately lead to decreasing the morbidity and mortality associated with a cancer diagnosis. The role of the nurse in helping patients to understand and manage hereditary cancer risk requires specialized knowledge of genetics and genomics concepts. Understanding Genomic and Hereditary Cancer Risk: A Handbook for Oncology Nurses provides background on basic genetic and genomic concepts, particularly those related to hereditary risk for developing cancer, to aid nurses in knowing when and why to refer patients. It also provides reliable information about how and why genetic and genomic testing can both aid in treatment decisions and also guide recommendations for cancer prevention and early detection. The nurse's role in genetic testing and counseling are discussed, as are questions and answers about types of testing, including direct-to-consumer genetic testing. Following genetic testing, most genetics professionals provide detailed information about recommendations for care, including recommendations for ongoing prevention and early detection. For patients who are found to have a harmful mutation, these recommendations can be extensive and are based on the personal and family medical history, as well as the specific variant. This book provides quick overviews of many of the more common hereditary variants as well as resources for more information. This handbook provides nurses with the essentials to understand genomic and hereditary cancer risk, to assist in facilitating interprofessional care with genetics and other oncology professionals, and to provide their patients with accurate and reassuring information"--

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Genetics: A Clinical Approach

Author : Xavier Llor
Publisher : McGraw Hill Professional
ISBN 13 : 1260440281
Total Pages : 474 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis Cancer Genetics: A Clinical Approach by : Xavier Llor

Download or read book Cancer Genetics: A Clinical Approach written by Xavier Llor and published by McGraw Hill Professional. This book was released on 2021-11-19 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ultimate guide to caring for and communicating with patients suffering with hereditary cancer syndromes Providing the essential tools needed to understand clinical cancer genetics, Cancer Genetics: A Clinical Approach builds your mastery of differential diagnosis formulation, all the available genetic testing options at your disposal, interpreting results logically and accurately, and educating patients and their families about effective cancer prevention methods. This unparalleled resource walks you through the process of effectively and thoughtfully counseling patients—from pre-test counseling and relaying test results to navigating the legal implications of hereditary conditions and coping with the resulting psychological challenges. Cancer Genetics: A Clinical Approach is ideal for both specialized cancer genetics clinics or any healthcare professional seeking to improve their skills in identifying patients with possible hereditary cancer syndromes and recognizing which ones should be referred to a high-risk/clinical genetics specialty program.

Molecular Genetics of Cancer

Author : John K. Cowell
Publisher : Gulf Professional Publishing
ISBN 13 : 9780121501006
Total Pages : 544 pages
Book Rating : 4.5/5 (1 download)

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Book Synopsis Molecular Genetics of Cancer by : John K. Cowell

Download or read book Molecular Genetics of Cancer written by John K. Cowell and published by Gulf Professional Publishing. This book was released on 2001 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first volume was published, there has been significant success in isolating genes responsible for particular cancers as well as a major improvement in our understanding of the molecular events leading to tumors. This book explores possible genetic treatments that can suppress cancer cells that have formed tumors and it presents the details of the isolation and characterization of new human cancer genes that have recently been identified. Molecular Genetics of Cancer, 2E is an essential book for anyone involved in cancer research and the search for a cure.

Cancer Genetics and Psychotherapy

Author : Parvin Mehdipour
Publisher : Springer
ISBN 13 : 3319645501
Total Pages : 1170 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Cancer Genetics and Psychotherapy by : Parvin Mehdipour

Download or read book Cancer Genetics and Psychotherapy written by Parvin Mehdipour and published by Springer. This book was released on 2017-09-20 with total page 1170 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide the readers with the most comprehensive and latest accounts of research and development in this field by emphasizing on the manner of relation between doctors and cancer patients in direction of improving the patients’ style of life. This book, partly, will deal with psychotherapy by considering cancer patients, benefits, hazards and also social impacts including life style. The social supports as the key and influential paradigms will be challenged as a comparative insight by considering the global unity in order to provide a reasonable model to improve the interaction between cancer and psychological nest. In this book, the real stories of cancer patient will be also provided. The initial insight of sections includes: 1) Brief classifications and key points of clinical and histopatological aspects of each organ. 2) Brief view of genetic alterations in each organ. 3) Therapeutic aspects. 4) Brief classifications and key points of Psychology in cancer. 5) The interactions of clinical aspects with psychological field.

Living with Hereditary Cancer Risk

Author : Kathy Steligo
Publisher : JHU Press
ISBN 13 : 1421444259
Total Pages : 496 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Living with Hereditary Cancer Risk by : Kathy Steligo

Download or read book Living with Hereditary Cancer Risk written by Kathy Steligo and published by JHU Press. This book was released on 2022-09-27 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book provides a comprehensive overview of hereditary cancer for a general audience, with coverage of the genetic tests available for detecting risk for heritable cancers as well as options for medical and surgical treatment"--

Cancer Genomics for the Clinician

Author : Ramaswamy Govindan, MD
Publisher : Springer Publishing Company
ISBN 13 : 082616868X
Total Pages : 184 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Cancer Genomics for the Clinician by : Ramaswamy Govindan, MD

Download or read book Cancer Genomics for the Clinician written by Ramaswamy Govindan, MD and published by Springer Publishing Company. This book was released on 2019-01-28 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Genomics for the Clinician is a practical guide to cancer genomics and its application to cancer diagnosis and care. The book begins with a brief overview of the various types of genetic alterations that are encountered in cancer, followed by accessible and applicable information on next generation sequencing technology and bioinformatics; tumor heterogeneity; whole genome, exome, and transcriptome sequencing; epigenomics; and data analysis and interpretation. Each chapter provides essential explanations of concepts, terminology, and methods. Also included are tips for interpreting and analyzing molecular data, as well as a discussion of molecular predictors for targeted therapies covering hematologic malignancies and solid tumors. The final chapter explains the use of FDA-approved genomic-based targeted therapies for breast cancer, lung cancer, sarcomas, gastrointestinal cancers, urologic cancers, head and neck cancer, thyroid cancer, and many more. Assembled in an accessible format specifically designed for the non-expert, this book provides the clinical oncologist, early career practitioner, and trainee with an essential understanding of the molecular and genetic basis of cancer and the clinical aspects that have led to advancements in diagnosis and treatment. With this resource, physicians and trainees will increase their breadth of knowledge and be better equipped to educate patients and families who want to know more about their genetic predispositions to cancer and the targeted therapies that could be considered and prescribed. Key Features: Describes how cancer genomics and next generation sequencing informs cancer screening, risk factors, therapeutic options, and clinical management across cancer types Explains what mutations are, what tests are needed, and how to interpret the results Provides information on FDA-approved targeted therapies that are being used in the clinic Covers different sequencing platforms and technologies and how they perform in research settings Includes access to the fully searchable eBook

Clinical Gynecologic Oncology E-Book

Author : Philip J. DiSaia
Publisher : Elsevier Health Sciences
ISBN 13 : 0323443168
Total Pages : 700 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Clinical Gynecologic Oncology E-Book by : Philip J. DiSaia

Download or read book Clinical Gynecologic Oncology E-Book written by Philip J. DiSaia and published by Elsevier Health Sciences. This book was released on 2017-02-04 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most readable, most comprehensive book in its field, Clinical Gynecologic Oncology, 9th Edition is the leading reference for diagnosis and treatment of gynecologic cancers – a must-have reference for improving outcomes and providing effective care. A "who’s who" list of contributing authors, under the editorial direction of Drs. Philip DiSaia and William Creasman, provides expert guidance on clinical presentations and management, now fully up to date with a brand-new design for faster, easier reference. Contains useful appendices covering staging, screening, nutritional therapy, toxicity criteria, blood component therapy, and radiation therapy. Covers hot topics such as multi-panel genetic testing, target therapies, sentinel node concept in endometrial cancer and vulvar cancer, and robotic surgery. Updates include new quick-reference features such as key point boxes with bulleted lists, highlighted key text, enhanced chapter outlines, and a brand-new design throughout. Includes up-to-date references and algorithms, making this text a comprehensive resource for clinical practice, personal study, and exam review. Helps you take advantage of the latest advances in early detection and improved treatment options for gynecologic cancers, especially uterine and cervical cancers.

A Practical Guide to Human Cancer Genetics

Author : S. V. Hodgson
Publisher : Cambridge University Press
ISBN 13 : 052168563X
Total Pages : 411 pages
Book Rating : 4.5/5 (216 download)

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Book Synopsis A Practical Guide to Human Cancer Genetics by : S. V. Hodgson

Download or read book A Practical Guide to Human Cancer Genetics written by S. V. Hodgson and published by Cambridge University Press. This book was released on 2007 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 2006 third edition of this very successful book provides a comprehensive and practical guide to the diagnosis and management of inherited disorders conferring susceptibility to cancer. Issues discussed include risk assessment, genetic counselling, predictive testing and organisation of a cancer genetics service. A full reference list gives access to background literature. With molecular information, screening guidelines and management advice, this new edition will provide geneticists and clinicians in all disciplines with an invaluable resource for screening, managing and advising patients.

Risky Genes

Author : Jessica Mozersky
Publisher : Routledge
ISBN 13 : 0415502284
Total Pages : 178 pages
Book Rating : 4.4/5 (155 download)

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Book Synopsis Risky Genes by : Jessica Mozersky

Download or read book Risky Genes written by Jessica Mozersky and published by Routledge. This book was released on 2013 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: What does it mean to be told you have an increased risk of genetic breast cancer because you are of Ashkenazi Jewish origin? In a time of ever increasing knowledge about variations in genetic disease risk among different populations, there is a pressing need for research regarding the implications of such information for members of high-risk populations. With first hand, intimate descriptions of women's experiences of being Jewish and of being at increased risk of genetic breast cancer, this book offers new insight into the ongoing debates regarding the implications of genetic research for populations, and of new genetic knowledge for individual and collective identity.

Cancer Gene Therapy

Author : David T. Curiel
Publisher : Springer Science & Business Media
ISBN 13 : 1592597858
Total Pages : 490 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Cancer Gene Therapy by : David T. Curiel

Download or read book Cancer Gene Therapy written by David T. Curiel and published by Springer Science & Business Media. This book was released on 2007-11-03 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete introduction and guide to the latest developments in cancer gene therapy-from bench to bedside. The authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize and eliminate cancer cells, and the targeting of the nonmalignant stromal cells that support their growth. They also thoroughly examine the advantages and limitations of the different therapies and detail strategies to overcome obstacles to their clinical implementation. Topics of special interest include vector-targeting techniques, the lessons learned to date from clinical trials of cancer gene therapy, and the regulatory guidelines for future trials. Noninvasive techniques to monitor the extent of gene transfer and disease regression during the course of treatment are also discussed.

Clinical Gynecology

Author : Eric J. Bieber
Publisher : Cambridge University Press
ISBN 13 : 1107040396
Total Pages : 1127 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Clinical Gynecology by : Eric J. Bieber

Download or read book Clinical Gynecology written by Eric J. Bieber and published by Cambridge University Press. This book was released on 2015-04-23 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.

A Practical Guide to Human Cancer Genetics

Author : Shirley V. Hodgson
Publisher : Cambridge University Press
ISBN 13 : 9780521649612
Total Pages : 354 pages
Book Rating : 4.6/5 (496 download)

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Book Synopsis A Practical Guide to Human Cancer Genetics by : Shirley V. Hodgson

Download or read book A Practical Guide to Human Cancer Genetics written by Shirley V. Hodgson and published by Cambridge University Press. This book was released on 1999-07-22 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This extensively updated and expanded edition provides the busy clinician with an essential overview of the latest developments in human cancer genetics--an area that has made significant advances since publication of the first edition. The opening section presents the principles of cancer genetics and introduces the basic concepts and mechanisms of tumorigenesis and inherited predisposition to cancer. The second part of the book provides information, on a systems basis, on the incidence, significance and management of predisposition to individual cancers. The final section deals with specific inherited cancer syndromes, giving practical guidance on clinical investigation, screening and management of affected patients and relatives at risk. The authors also provide up-to-date details of the genetic mapping of inherited cancer syndromes and the molecular genetic changes in individual cancers. Finally, an appendix provides a helpful revision guide to the fundamental principles of genetics. This practical and clear account will benefit clinicians and research workers in oncology, genetics, surgery and general medicine.