Synthetic Polypeptides as Antigens

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Publisher : Elsevier
ISBN 13 : 0080858880
Total Pages : 245 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Synthetic Polypeptides as Antigens by : J.P. Briand

Download or read book Synthetic Polypeptides as Antigens written by J.P. Briand and published by Elsevier. This book was released on 1988-11-01 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Polypeptides as Antigens is the first volume to give a comprehensive treatment under one cover of the various techniques used for synthesizing peptides by the solid phase approach, for coupling them to carrier molecules and analyzing their immunochemical activity by a variety of immunoassays. This book also describes methods for analyzing the antigenic structure of proteins and predicting the location of their antigenic sites. Recent advances in the detection of gene products with antipeptide antibodies, and the still controversial use of synthetic peptides as vaccines are also described. The book provides: - detailed descriptions of procedures - extensive bibliography - detailed analysis of the structural basis of antigenicity in proteins Synthetic Polypeptides as Antigens is intended for researchers and graduate students in molecular biology, protein structure, immunology, virology, and microbiology. Those using synthetic peptides as immunological probes will find this a most useful book, as will those wishing to overcome the difficulties of achieving antigenic mimicry by synthesis.

Synthetic Peptides as Antigens

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470513292
Total Pages : 318 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Synthetic Peptides as Antigens by : Ruth Porter

Download or read book Synthetic Peptides as Antigens written by Ruth Porter and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Synthetic Polypeptides as Antigens

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Author :
Publisher :
ISBN 13 : 9780444809759
Total Pages : 227 pages
Book Rating : 4.8/5 (97 download)

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Book Synopsis Synthetic Polypeptides as Antigens by : M. H. V. Van Regenmortel

Download or read book Synthetic Polypeptides as Antigens written by M. H. V. Van Regenmortel and published by . This book was released on 1988 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Polypeptides as Antigens is the first volume to give a comprehensive treatment under one cover of the various techniques used for synthesizing peptides by the solid phase approach, for coupling them to carrier molecules and analyzing their immunochemical activity by a variety of immunoassays. This book also describes methods for analyzing the antigenic structure of proteins and predicting the location of their antigenic sites. Recent advances in the detection of gene products with antipeptide antibodies, and the still controversial use of synthetic peptides as vaccines are also described. The book provides: - detailed descriptions of procedures - extensive bibliography - detailed analysis of the structural basis of antigenicity in proteins Synthetic Polypeptides as Antigens is intended for researchers and graduate students in molecular biology, protein structure, immunology, virology, and microbiology. Those using synthetic peptides as immunological probes will find this a most useful book, as will those wishing to overcome the difficulties of achieving antigenic mimicry by synthesis.

Synthetic Peptides as Antigens

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Author :
Publisher : Elsevier Science
ISBN 13 : 9780444821751
Total Pages : 380 pages
Book Rating : 4.8/5 (217 download)

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Book Synopsis Synthetic Peptides as Antigens by : S. Muller

Download or read book Synthetic Peptides as Antigens written by S. Muller and published by Elsevier Science. This book was released on 1999-12-09 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This newest edition to the Laboratory Techniques Series gives current state of the art use of synthetic peptides in molecular biology and practical protocols on how to conjugate peptides, immunize animals with peptides and monitor immune responses to peptides in vitro. It gives background information on antigenic specificity, prediction of antigenic sites in proteins and applications of peptides in immunology and virology, as probes in diagnosis and as vaccines. The book also describes antigenicity of proteins and methods to localize antigenic sites as well as methods for predicting epitoxes, and gives detailed protocols for peptide-carrier conjugation, immunization with peptides, and peptide immunoassays. The volume also describes typical use of antipeptide antibodies in molecular and cellular biology as well as the use of peptides in the diagnosis of viral infections and autoimmune diseases, and the use of peptides as potential synthetic vaccines. An excellent edition to an excellent series, available in hardbound and paperback.

Synthetic Polypeptides as Antigens

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Author :
Publisher :
ISBN 13 : 9780720442007
Total Pages : 0 pages
Book Rating : 4.4/5 (42 download)

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Book Synopsis Synthetic Polypeptides as Antigens by :

Download or read book Synthetic Polypeptides as Antigens written by and published by . This book was released on 1988 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Synthetic Polypeptides as Antigens

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Author :
Publisher :
ISBN 13 : 9780720442007
Total Pages : 0 pages
Book Rating : 4.4/5 (42 download)

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Book Synopsis Synthetic Polypeptides as Antigens by : Marc H. V. VanRegenmortel

Download or read book Synthetic Polypeptides as Antigens written by Marc H. V. VanRegenmortel and published by . This book was released on 1988 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Peptide Antibodies

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Author :
Publisher : Springer Nature
ISBN 13 : 1071639145
Total Pages : 270 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Peptide Antibodies by : Gunnar Houen

Download or read book Peptide Antibodies written by Gunnar Houen and published by Springer Nature. This book was released on with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Structure of Antigens

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Publisher : CRC Press
ISBN 13 : 9780849388675
Total Pages : 404 pages
Book Rating : 4.3/5 (886 download)

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Book Synopsis Structure of Antigens by : Marc H. V. Van Regenmortel

Download or read book Structure of Antigens written by Marc H. V. Van Regenmortel and published by CRC Press. This book was released on 1992-12-07 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structure of Antigens discusses a variety of topics dealing with the structural basis of antigenicity. Topics include the analytical methods used to elucidate the structure of antigens, the structure of antibodies, the principles underlying modern immunoassays and the measurement of antibody binding affinity, and physicochemical principles and methodological aspects. The book also considers major groups of antigens distinguished by their functional activity and biological role (e.g., drugs, autoantigens, snake toxins, allergens) or by their association with particular biological systems (e.g., antigens of microorganisms). Structure of Antigens will provide a current, useful, reference for researchers and graduate students in all fields of biological science who need an overview of antigenic specificity. VOLUME II

Immunobiology of Proteins and Peptides IV

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1468454420
Total Pages : 332 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Immunobiology of Proteins and Peptides IV by : M. Zouhair Atassi

Download or read book Immunobiology of Proteins and Peptides IV written by M. Zouhair Atassi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This symposium was established in 1976 for the purpose of bringing to gether once every two or three years, active investigators in the fore front of contemporary immunology, to present their findings and to discuss their significance in the light of current concepts and to identify important new directions of investigation. The founding of the symposium was stimulated by the achievement of major breakthroughs in the under standing of the immune recognition of proteins and peptides. We believed that these breakthroughs will lead to the creation of a new generation of peptides which should have enormous potential in biological, therapeutic and basic applications. This anticipated explosion has finally occurred and many applications of these peptides are now being realized. The main symposia topics of the fourth symposium were: T-cell recognition of proteins, structure and function of the T-cell receptor, presentation of protein antigens, recycling and activation of membrane receptor molecules, Ir-gene control of T-cell responses and methods of cell separation. The molecular features recognized by antibodies on proteins were the first immune recognition sites to be local ized and confirmed by synthetic peptides. The complete antigenic structures of several proteins have been defined, and individual antigenic sites have been described on many more proteins. More recently, major breakthroughs have been reported in the immune recognition of proteins by T cells.

Nature of Immune Tolerance by Means of Synthetic Polypeptide Antigens

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Author :
Publisher :
ISBN 13 :
Total Pages : 95 pages
Book Rating : 4.:/5 (227 download)

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Book Synopsis Nature of Immune Tolerance by Means of Synthetic Polypeptide Antigens by : Sara Bauminger

Download or read book Nature of Immune Tolerance by Means of Synthetic Polypeptide Antigens written by Sara Bauminger and published by . This book was released on 1966 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contents: Specificity of Immunological Tolerance to Poly-DL-alanyl Proteins; The Immune Response of Inbred Strains of Guinea-pigs to Polylysyl Rabbit Serum Albumin; Differences in Immune Response to Synthetic Antigens in Two Inbred Strains of Guinea Pigs; Induction of Unresponsiveness to Delayed-Type Reactions in Guinea Pigs; Formation and Isolation of Rabbit Antibodies to a Synthetic Antigen of Low Molecular Weight; Competition of Antigenic Determinants; Further Studies on the Immunogenicity of D-Amino Acid Polymers; Immune Response to Collagen-like Synthetic Polypeptides.

Synthetic Peptides in Biology and Medicine

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Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 276 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Synthetic Peptides in Biology and Medicine by : Kari Alitalo

Download or read book Synthetic Peptides in Biology and Medicine written by Kari Alitalo and published by Elsevier Science & Technology. This book was released on 1985 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Use of Synthetic Antigens for Diagnosis of Infectious Diseases

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Publisher :
ISBN 13 :
Total Pages : 80 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis The Use of Synthetic Antigens for Diagnosis of Infectious Diseases by : WHO Scientific Group on the Use of Synthetic Antigens for Diagnosis of Infectious Diseases

Download or read book The Use of Synthetic Antigens for Diagnosis of Infectious Diseases written by WHO Scientific Group on the Use of Synthetic Antigens for Diagnosis of Infectious Diseases and published by . This book was released on 1989 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunobiology of Proteins and Peptides-III

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1468479741
Total Pages : 278 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Immunobiology of Proteins and Peptides-III by : M. Z. Atassi

Download or read book Immunobiology of Proteins and Peptides-III written by M. Z. Atassi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This symposia series, founded in 1976, is devoted to the advancement and dissemination of knowledge in the field in immunology, particularly as it relates to the immune recognition and responses to protein and peptide antigens. Leading investigators are convened every 2 or 3 years for the purpose of consolidating the research on protein and peptide antigens of defined structure and to focus on these findings in the context of contemporary immunology. Each symposium has focussed on a particular aspect of molecular and cellular immunology of proteins and peptides. It is extremely gratifying that, in the last 2-3 years, the scientific community has shown a heightened interest in the study and understanding of protein and peptide antigens. The third symposium was devoted to viral and bacterial antigens. Great advances have been made in recent years in the elucidation and synthesis of protein antigenic sites. These, together with advances in cloning, expression and sequencing of protein genes, have offered new avenues for the preparation of synthetic vaccines for viral, bacterial and other antigens. Such vaccines have been the aspiration of immunologists for over 20 years. The meeting has served to integrate and correlate the current knowledge of these systems with developing trends in immunology and to identify the most promising new directions for future investigations.

Catalytic Antibodies

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Publisher : John Wiley & Sons
ISBN 13 : 0470514116
Total Pages : 270 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Catalytic Antibodies by : Derek J. Chadwick

Download or read book Catalytic Antibodies written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic antibodies. The recognition that monoclonal antibodies can possess catalytic activity is a recent advance with profound ramifications for chemistry. In addition to their potential commercial applications as catalysts for reactions, for which there are no known enzymes, antibodies promise to provide valuable insight into the detailed mechanisms of biological catalysis and organic chemistry.

Peptide Antigens

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Publisher : Irl Press
ISBN 13 : 9780199634521
Total Pages : 252 pages
Book Rating : 4.6/5 (345 download)

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Book Synopsis Peptide Antigens by : G. Brian Wisdom

Download or read book Peptide Antigens written by G. Brian Wisdom and published by Irl Press. This book was released on 1994 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptide antigens and anti-peptide antibodies are widely used in biochemistry and molecular biology for the measurement, location, and purification of specific oligopeptides. More recently the application of these reagents has expanded, for example in the identification and mapping of the binding sites of antibodies and T-cell receptors and in the identification and characterization of proteins which are known only by their primary structure. This volume provides practical guidance to the major techniques used in the exploitation of peptide antigens and anti-peptide antibodies. The chapters give detailed protocols for the prediction of epitopes, peptides synthesis, the preparation of peptide immunogens, immunoaffinity chromatography, immunoassays, and the mapping of epitopes using both synthetic peptides and phage display systems. Peptide Antigens: A Practical Approach covers all practical aspects of this important and growing subject. It is a unique compendium of methods for workers in biochemistry, molecular biology, and immunology who need to use this technology in their research.

Synthetic Peptides

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Publisher : Oxford University Press
ISBN 13 : 9780198030430
Total Pages : 404 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Synthetic Peptides by : Gregory Grant

Download or read book Synthetic Peptides written by Gregory Grant and published by Oxford University Press. This book was released on 2002-04-04 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first synthetic peptides were produced a century ago. In the ensuing period, they have developed as valuable research tools that are readily available to all researchers. However, since most researchers do not make their own peptides, they are often unfamiliar with not only the synthetic chemistry but also with important and useful aspects of design, analysis, handling, and applications. This volume is the second edition of a volume that was first published 10 years ago. It is written by experts in the field who provide detailed descriptions as well as practical advice for producing and using synthetic peptides. The various chapters cover peptide design considerations, the synthetic chemistry, the evaluation of the synthetic product, and the modern applications of synthetic peptides. This includes the basic principles of peptide structure, analysis and chain assembly as well as the latest in selective disulfide bond formation, new strategies for the production of large peptides, and sequencing peptides by mass spectrometry. This book was designed with the intent of providing useful information both for the novices to the field as well as more seasoned practitioners. Its contents will help prevent problems commonly encountered and allow scientists to optimize their use of synthetic peptides.

Immunobiology of Proteins and Peptides—II

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Publisher : Springer Science & Business Media
ISBN 13 : 1468443313
Total Pages : 227 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Immunobiology of Proteins and Peptides—II by : M. Zouhair Atassi

Download or read book Immunobiology of Proteins and Peptides—II written by M. Zouhair Atassi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune response is largely dependent on molecular inter actions involving proteins. The recognition of antigen molecules, whether they are proteins or non-proteins, whether they are self or non-self, takes place at the molecular-cellular interface through membrane receptor molecules that are proteins. The initial step of recognition activates a complex series of cellular events requiring some mechanism of cell-cell interactions and communi cations, eventually leading to antibody production. This biolo gical cascade is controlled at several positions along its con secutive pathways by protein molecules, either in the free form or as receptors on membranes of cells committed to this activity. Clearly, then, the proper understanding of the response by cells of the immune system will depend, to a great measure, on the definition of the molecular events involving protein interactions. Obviously, cells work via molecules and molecules work via cells and, at this level of functional resolution, molecular immunology and cellular immunology will merge and will depend heavily on protein chemistry.