Synthesis of 1S-ethyl-4-substituted Quinolizidines and Other Potentially Bioactive Compounds

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (892 download)

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Book Synopsis Synthesis of 1S-ethyl-4-substituted Quinolizidines and Other Potentially Bioactive Compounds by : Vladislav Semak

Download or read book Synthesis of 1S-ethyl-4-substituted Quinolizidines and Other Potentially Bioactive Compounds written by Vladislav Semak and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biological Activities of Alkaloids

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Publisher : MDPI
ISBN 13 : 3039289276
Total Pages : 270 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Biological Activities of Alkaloids by : Sabino Aurelio Bufo

Download or read book Biological Activities of Alkaloids written by Sabino Aurelio Bufo and published by MDPI. This book was released on 2020-05-13 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products are increasingly attracting attention from both basic and applied science. Plant secondary metabolites, especially alkaloids, are receiving interest from a wide range of researchers due to their biological activity. They are produced to protect plants from diseases and herbivores. Therefore, they reveal a toxic activity that affects organisms at various levels of biological organization. A growing amount of research is proving their antimicrobial, antifungal, insecticidal, and anticancer activities. That makes them applicable in various fields from medicine, to pharmacology, veterinary, and toxicology, to crop protection. This Special Issue of Toxins, “Biological Activities of Alkaloids: From Toxicology to Pharmacology", collects 15 manuscripts describing the ecological, biological, pharmacological, and toxicological effects as well as structural and analytical aspects of plant alkaloids, their mode of action, and possible application in veterinary, medicine, and plant protection. These studies prove the potential for alkaloid application in various areas of science.

Diversity Oriented Synthesis

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Publisher : Frontiers Media SA
ISBN 13 : 2889457885
Total Pages : 150 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Diversity Oriented Synthesis by : Andrea Basso

Download or read book Diversity Oriented Synthesis written by Andrea Basso and published by Frontiers Media SA. This book was released on 2019-03-22 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Has the concept of Diversity Oriented Synthesis remained unchanged over these two decades, or do we observe improvements or deviations from the original guidelines drawn by the pioneers? The aim of this Research Topic is to collect contributions on the state-of-the-art and progress of Diversity Oriented Synthesis, and to foresee its shape in the next decade.

Plant-derived Natural Products

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Publisher : Springer Science & Business Media
ISBN 13 : 0387854983
Total Pages : 588 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Plant-derived Natural Products by : Anne E. Osbourn

Download or read book Plant-derived Natural Products written by Anne E. Osbourn and published by Springer Science & Business Media. This book was released on 2009-07-07 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.

World Malaria Report 2015

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Publisher : World Health Organization
ISBN 13 : 9241565152
Total Pages : 283 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis World Malaria Report 2015 by : World Health Organization

Download or read book World Malaria Report 2015 written by World Health Organization and published by World Health Organization. This book was released on 2016-01-30 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Malaria Report 2015assesses global malaria disease trends and changes in the coverage and financing of malaria control programs between 2000 and 2015. It also summarizes progress towards international targets, and provides regional and country profiles that summarize trends in each WHO region and each country with malaria. The report is produced with the help of WHO regional and country offices, ministries of health in endemic countries, and a broad range of other partners. The data presented are assembled from the 96 countries and territories with ongoing malaria transmission, and a further five countries that have recently eliminated malaria. Most data are those reported for 2014 and 2015, although in some cases projections have been made into 2015, to assess progress towards targets for 2015.

Anionic Annulations in Organic Synthesis

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Publisher : Elsevier
ISBN 13 : 0128138017
Total Pages : 466 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Anionic Annulations in Organic Synthesis by : Dipakranjan Mal

Download or read book Anionic Annulations in Organic Synthesis written by Dipakranjan Mal and published by Elsevier. This book was released on 2018-10-25 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anionic Annulations in Organic Synthesis: A Versatile and Prolific Class of Ring-Forming Reactions is a comprehensive review of the main annulations for the construction of cyclic structures and their use in the total synthesis of functional molecules. The book explores in detail the Hauser, Robinson, Sammes, and Myers annulations, all of which are beneficial to constructing substrates with complex molecular structures suitable for pharmaceutical purposes. This volume begins with an in-depth introduction on the history and perspectives of annulations. It then covers different categories of annulation in each chapter, examining their application to drug synthesis for a range of different medicinal compounds. Anionic Annulations in Organic Synthesis delivers a thorough analysis of the topic and provides the tools necessary to master anionic organic chemistry. It is a valuable resource for chemists, researchers, and students seeking a complete and detailed understanding of anionic annulations. - Serves as a useful tool to both academic and industrial researchers in the field - Includes numerous examples of anionic annulations and how to apply them practically in research and industry - Features anionic annulations that are particularly effective for the synthesis of polyoxygenated polycyclic compounds

Indole Ring Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 0470512180
Total Pages : 704 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Indole Ring Synthesis by : Gordon W. Gribble

Download or read book Indole Ring Synthesis written by Gordon W. Gribble and published by John Wiley & Sons. This book was released on 2016-08-08 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade — highlighted by the power of transition metal catalysis — this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known. Following presentation of the classic indole ring syntheses and many newer methods, coverage continues with indole ring syntheses via pyrroles, indolines, oxindoles, isatins, radical and photochemical reactions, aryne cycloadditions. This extensive volume concludes with the modern transition metal–catalyzed indole ring syntheses that utilize copper, palladium, rhodium, gold, ruthenium, platinum, and other metals to fashion the indole ring Indole Ring Synthesis is a comprehensive, authoritative and up-to-date guide to the synthesis of this important heterocycle for organic chemists, pharmaceutical researchers and those interested in the chemistry of natural products.

Sonochemical Reactions

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Publisher : BoD – Books on Demand
ISBN 13 : 1838800018
Total Pages : 162 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Sonochemical Reactions by : Selcan Karakuş

Download or read book Sonochemical Reactions written by Selcan Karakuş and published by BoD – Books on Demand. This book was released on 2020-03-25 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was written by authors in the field of ultrasound-assited synthesis and their applications. Among others, some of the topics covered are: ultrasound-assited synthesis of metal/metal oxide nanoparticles, graphene nanosheets, and ultrasound applications. In this book, authors focused on recent studies, applications, and new technological developments on fundamental properties of the ultrasound process.

The Science of Flavonoids

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Publisher : Springer Science & Business Media
ISBN 13 : 9780387745503
Total Pages : 300 pages
Book Rating : 4.7/5 (455 download)

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Book Synopsis The Science of Flavonoids by : Erich Grotewold

Download or read book The Science of Flavonoids written by Erich Grotewold and published by Springer Science & Business Media. This book was released on 2008 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the only book of its kind to provide an overview of the science of flavonoids in plants.

Alkaloids - Secrets of Life:

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Publisher : Elsevier
ISBN 13 : 0080475337
Total Pages : 325 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Alkaloids - Secrets of Life: by : Tadeusz Aniszewski

Download or read book Alkaloids - Secrets of Life: written by Tadeusz Aniszewski and published by Elsevier. This book was released on 2007-03-22 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alkaloids, represent a group of interesting and complex chemical compounds, produced by the secondary metabolism of living organisms in different biotopes. They are relatively common chemicals in all kingdoms of living organisms in all environments. Two hundred years of scientific research has still not fully explained the connections between alkaloids and life.Alkaloids-Chemistry, Biological Significance, Applications and Ecological Role provides knowledge on structural typology, biosynthesis and metabolism in relation to recent research work on alkaloids. Considering an organic chemistry approach to alkaloids using biological and ecological explanation. Within the book several questions that persist in this field of research are approached as are some unresearched areas. The book provides beneficial text for an academic and professional audience and serves as a source of knowledge for anyone who is interested in the fascinating subject of alkaloids. Each chapter features an abstract. Appendices are included, as are a listing of alkaloids, plants containing alkaloids and some basic protocols of alkaloid analysis.* Presents the ecological role of alkaloids in nature and ecosystems * Interdisciplinary and reader friendly approach* Up-to-date knowledge

Biochemical Targets of Plant Bioactive Compounds

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Publisher : CRC Press
ISBN 13 : 0203013719
Total Pages : 864 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Biochemical Targets of Plant Bioactive Compounds by : Gideon Polya

Download or read book Biochemical Targets of Plant Bioactive Compounds written by Gideon Polya and published by CRC Press. This book was released on 2003-05-15 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: When introduced to the human body, bioactive metabolites produced by plants for self defense bind to particular biochemical targets, most notably to proteins involved in signaling by hormones and neurotransmitters. This, essentially, is the basis for the effects of herbal medicine. While herbal medicine preparations may act by complex synergistic interactions, molecular explanations of herbal medicine efficacy and side effects ultimately require definition of the biochemical targets of individual plant bioactive constituents. Biochemical Targets of Plant Bioactive Compounds is a comprehensive and user-friendly reference guide to biochemical targets of plant defensive compounds. With 500 pages of tables, it presents a mine of succinctly summarized information relating to bioactive compound structures, plant sources, biochemical targets and physiological effects that can be readily accessed via chemical compound, plant genus, plant common name and subject indexes. With introductory chapters providing reviews of the structural diversity of plant defensive compounds and biochemistry, this book is an invaluable reference for biomedical professionals in the fields of alternative/complementary medicine, natural product chemistry, toxicology, pharmacology, and botany.

Aziridines and Epoxides in Organic Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 9783527312139
Total Pages : 532 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Aziridines and Epoxides in Organic Synthesis by : Andrei K. Yudin

Download or read book Aziridines and Epoxides in Organic Synthesis written by Andrei K. Yudin and published by John Wiley & Sons. This book was released on 2006-02-20 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aziridines and epoxides are among the most widely used intermediates in organic synthesis, acting as precursors to complex molecules due to the strains incorporated in their skeletons. Besides their importance as reactive intermediates, many biologically active compounds also contain these three-membered rings. Filling a gap in the literature, this clearly structured book presents the much needed information in a compact and concise way. The renowned editor has succeeded in gathering together excellent authors to cover synthesis, applications, and the biological aspects in equal depth. Divided roughly equally between aziridines and epoxides, the twelve chapters discuss: * Synthesis of aziridines * Nucleophilic ring-opening of aziridines and epoxides * Organic synthesis with aziridine building blocks * Vinyl aziridines in organic synthesis * Diastereoselective aziridination reagents * Synthetic aspects of aziridinomitocene chemistry * Biosynthesis of biologically important aziridines * Organic catalysis of epoxide and aziridine ring formation * Metal-mediated synthesis of epoxides * Asymmetric epoxide ring opening chemistry * Epoxides in complex molecule synthesis * Biological activity of epoxide-containing molecules A high-quality reference manual for academic and industrial chemists alike.

Phytochemicals as Lead Compounds for New Drug Discovery

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Publisher : Elsevier
ISBN 13 : 0128178914
Total Pages : 382 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Phytochemicals as Lead Compounds for New Drug Discovery by : Chukwuebuka Egbuna

Download or read book Phytochemicals as Lead Compounds for New Drug Discovery written by Chukwuebuka Egbuna and published by Elsevier. This book was released on 2019-09-07 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases. Written by a global team of experts, Phytochemicals as Lead Compounds for New Drug Discovery is an ideal resource for drug developers, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, and other researchers in those fields. It will also be very valuable to professors, students, and researchers in this domain. - Presents fundamental concepts and factors affecting choice for plant-based products - Details the FDA drug candidacy acceptance criteria, including bottlenecks and way forward - Highlights recent advances in computational-based drug discovery - Focuses on the discovery of new drugs and potential druggable targets for the treatment of chronic diseases of world importance

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1832 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1832 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hydroformylation for Organic Synthesis

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Publisher : Springer
ISBN 13 : 3642450598
Total Pages : 233 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Hydroformylation for Organic Synthesis by : Maurizio Taddei

Download or read book Hydroformylation for Organic Synthesis written by Maurizio Taddei and published by Springer. This book was released on 2014-07-08 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Role of Metals and Ligands in Organic Hydroformylation, by Luca Gonsalvi, Antonella Guerriero, Eric Monflier, Frédéric Hapiot, Maurizio Peruzzini. Hydroformylation in Aqueous Biphasic Media Assisted by Molecular Receptors, by Frédéric Hapiot, Hervé Bricout, Sébastien Tilloy, Eric Monflier. Asymmetric Hydroformylation, by Bernabé F. Perandones, Cyril Godard, Carmen Claver. Domino Reactions Triggered by Hydroformylation, by Elena Petricci, Elena Cini. Rhodium-Catalyzed Hydroformylation in Fused Azapolycycles Synthesis, by Roberta Settambolo. Hydroformylation in Natural Product Synthesis, by Roderick W. Bates, Sivarajan Kasinathan.

Medicinal Natural Products

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Publisher : John Wiley & Sons
ISBN 13 : 9780471496410
Total Pages : 524 pages
Book Rating : 4.4/5 (964 download)

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Book Synopsis Medicinal Natural Products by : Paul M. Dewick

Download or read book Medicinal Natural Products written by Paul M. Dewick and published by John Wiley & Sons. This book was released on 2002-01-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.

Alkaloids

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Publisher : Springer Science & Business Media
ISBN 13 : 1475729057
Total Pages : 492 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Alkaloids by : Margaret F. Roberts

Download or read book Alkaloids written by Margaret F. Roberts and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not since the late 1970s has a single work presented the biology of this heterogenous group of secondary alkaloids in such depth. Alkaloids, a unique treatise featuring leaders in the field, presents both the historical use of alkaloids and the latest discoveries in the biochemistry of alkaloid production in plants alkaloid ecology, including marine invertebrates, animal and plant parasites, and alkaloids as antimicrobial and current medicinal use . Highlights include chapters on the chemical ecology of alkaloids in host-predator interactions, and on the compartmentation of alkaloids synthesis, transport, and storage. Extensive cross-referencing in tabular format makes this volume an excellent reference.