Intentional Human Dosing Studies for EPA Regulatory Purposes

Download Intentional Human Dosing Studies for EPA Regulatory Purposes PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309166411
Total Pages : 226 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Intentional Human Dosing Studies for EPA Regulatory Purposes by : National Research Council

Download or read book Intentional Human Dosing Studies for EPA Regulatory Purposes written by National Research Council and published by National Academies Press. This book was released on 2004-06-04 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: The EPA commissioned The National Academies to provide advice on the vexing question of whether and, if so, under what circumstances EPA should accept and consider intentional human dosing studies conducted by companies or other sources outside the agency (so-called third parties) to gather evidence relating to the risks of a chemical or the conditions under which exposure to it could be judged safe. This report recommends that such studies be conducted and used for regulatory purposes only if all of several strict conditions are met, including the following: The study is necessary and scientifically valid, meaning that it addresses an important regulatory question that can't be answered with animal studies or nondosing human studies; The societal benefits of the study outweigh any anticipated risks to participants. At no time, even when benefits beyond improved regulation exist, can a human dosing study be justified that is anticipated to cause lasting harm to study participants; and All recognized ethical standards and procedures for protecting the interests of study participants are observed. In addition, EPA should establish a Human Studies Review Board (HSRB) to evaluate all human dosing studiesâ€"both at the beginning and upon completion of the experimentsâ€"if they are carried out with the intent of affecting the agency's policy-making.

Philosophy of Science

Download Philosophy of Science PDF Online Free

Author :
Publisher : Taylor & Francis
ISBN 13 : 1351499750
Total Pages : 434 pages
Book Rating : 4.3/5 (514 download)

DOWNLOAD NOW!


Book Synopsis Philosophy of Science by : Mario Bunge

Download or read book Philosophy of Science written by Mario Bunge and published by Taylor & Francis. This book was released on 2017-09-04 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published as Scientific Research, this pair of volumes constitutes a fundamental treatise on the strategy of science. Mario Bunge, one of the major figures of the century in the development of a scientific epistemology, describes and analyzes scientific philosophy, as well as discloses its philosophical presuppositions. This work may be used as a map to identify the various stages in the road to scientific knowledge.Philosophy of Science is divided into two volumes, each with two parts. Part 1 offers a preview of the scheme of science and the logical and semantical took that will be used throughout the work. The account of scientific research begins with part 2, where Bunge discusses formulating the problem to be solved, hypothesis, scientific law, and theory.The second volume opens with part 3, which deals with the application of theories to explanation, prediction, and action. This section is graced by an outstanding discussion of the philosophy of technology. Part 4 begins with measurement and experiment. It then examines risks in jumping to conclusions from data to hypotheses as well as the converse procedure.Bunge begins this mammoth work with a section entitled ""How to Use This Book."" He writes that it is intended for both independent reading and reference as well as for use in courses on scientific method and the philosophy of science. It suits a variety of purposes from introductory to advanced levels. Philosophy of Science is a versatile, informative, and useful text that will benefit professors, researchers, and students in a variety of disciplines, ranging from the behavioral and biological sciences to the physical sciences.

The Justification of Scientific Change

Download The Justification of Scientific Change PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9401017344
Total Pages : 146 pages
Book Rating : 4.4/5 (1 download)

DOWNLOAD NOW!


Book Synopsis The Justification of Scientific Change by : C.R. Kordig

Download or read book The Justification of Scientific Change written by C.R. Kordig and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book I discuss the justification of scientific change and argue that it rests on different sorts of invariance. Against this background I con sider notions of observation, meaning, and regulative standards. My position is in opposition to some widely influential and current views. Revolutionary new ideas concerning the philosophy of science have recently been advanced by Feyerabend, Hanson, Kuhn, Toulmin, and others. There are differences among their views and each in some respect differs from the others. It is, however, not the differences, but rather the similarities that are of primary concern to me here. The claim that there are pervasive presuppositions fundamental to scientific in vestigations seems to be essential to the views of these men. Each would further hold that transitions from one scientific tradition to another force radical changes in what is observed, in the meanings of the terms employed, and in the metastandards involved. They would claim that total replace ment, not reduction, is what does, and should, occur during scientific revolutions. I argue that the proposed arguments for radical observational variance, for radical meaning variance, and for radical variance of regulative standards with respect to scientific transitions all fail. I further argue that these positions are in themselves implausible and methodologically undesirable. I sketch an account of the rationale of scientific change which preserves the merits and avoids the shortcomings of the approach of radical meaning variance theorists.

The Justification of Science and the Rationality of Religious Belief

Download The Justification of Science and the Rationality of Religious Belief PDF Online Free

Author :
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.X/5 (1 download)

DOWNLOAD NOW!


Book Synopsis The Justification of Science and the Rationality of Religious Belief by : Michael C. Banner

Download or read book The Justification of Science and the Rationality of Religious Belief written by Michael C. Banner and published by Oxford University Press, USA. This book was released on 1990 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this critical examination of recent accounts of the nature of science and of its justification given by Kuhn, Popper, Lakatos, Laudan, and Newton-Smith, Banner contends that models of scientific rationality which are used in criticism of religious beliefs are in fact often inadequate as accounts of the nature of science. He argues that a realist philosophy of science both reflects the character of science and scientific justifications, and suggests that religious belief could be given a justification of the same sort.

Revisiting Discovery and Justification

Download Revisiting Discovery and Justification PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402042515
Total Pages : 245 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!


Book Synopsis Revisiting Discovery and Justification by : Jutta Schickore

Download or read book Revisiting Discovery and Justification written by Jutta Schickore and published by Springer Science & Business Media. This book was released on 2006-04-18 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The distinction between the contexts of discovery and justification has left a turbulent wake in the philosophy of science. This book recognizes the need to re-open the debate about the nature, development, and significance of the context distinction, about its merits and flaws. The discussion clears the ground for the productive and fruitful integration of these new developments into philosophy of science.

Fault-Tracing: Against Quine-Duhem

Download Fault-Tracing: Against Quine-Duhem PDF Online Free

Author :
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110685043
Total Pages : 232 pages
Book Rating : 4.1/5 (16 download)

DOWNLOAD NOW!


Book Synopsis Fault-Tracing: Against Quine-Duhem by : Sam Mitchell

Download or read book Fault-Tracing: Against Quine-Duhem written by Sam Mitchell and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-09-21 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is widely believed in philosophy of science that nobody can claim that any verdict of science is forced upon us by the effects of a physical world upon our sense organs and instruments. The Quine-Duhem problem supposedly allows us to resist any conclusion. Views on language aside, Quine is supposed to have shown this decisively. But it is just false. In many scientific examples, there is simply no room to doubt that a particular hypothesis is responsible for a refutation or established by the observations. Fault Tracing shows how to play independently established hypotheses against each other to determine whether an arbitrary hypothesis needs to be altered in the light of (apparently) refuting evidence. It analyses real examples from natural science, as well as simpler cases. It argues that, when scientific theories have a structure that prevents them from using this method, the theory looks wrong, and is subject to serious criticism. This is a new, and potentially far-reaching, theory of empirical justification.

Revisiting Discovery and Justification

Download Revisiting Discovery and Justification PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9781402042508
Total Pages : 264 pages
Book Rating : 4.0/5 (425 download)

DOWNLOAD NOW!


Book Synopsis Revisiting Discovery and Justification by : Jutta Schickore

Download or read book Revisiting Discovery and Justification written by Jutta Schickore and published by Springer Science & Business Media. This book was released on 2006-01-27 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The distinction between the contexts of discovery and justification has had a turbulent career in philosophy of science. This book presents a debate about the nature, development, and significance of the context distinction, about its merits and flaws. It provides readings and analyses of the original textual sources for the context distinction.

Philosophy of Science

Download Philosophy of Science PDF Online Free

Author :
Publisher : Routledge
ISBN 13 : 1351499742
Total Pages : 562 pages
Book Rating : 4.3/5 (514 download)

DOWNLOAD NOW!


Book Synopsis Philosophy of Science by : Mario Bunge

Download or read book Philosophy of Science written by Mario Bunge and published by Routledge. This book was released on 2017-09-04 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published as Scientific Research, this pair of volumes constitutes a fundamental treatise on the strategy of science. Mario Bunge, one of the major figures of the century in the development of a scientific epistemology, describes and analyzes scientific philosophy, as well as discloses its philosophical presuppositions. This work may be used as a map to identify the various stages in the road to scientific knowledge.Philosophy of Science is divided into two volumes, each with two parts. Part 1 offers a preview of the scheme of science and the logical and semantical took that will be used throughout the work. The account of scientific research begins with part 2, where Bunge discusses formulating the problem to be solved, hypothesis, scientific law, and theory.The second volume opens with part 3, which deals with the application of theories to explanation, prediction, and action. This section is graced by an outstanding discussion of the philosophy of technology. Part 4 begins with measurement and experiment. It then examines risks in jumping to conclusions from data to hypotheses as well as the converse procedure.Bunge begins this mammoth work with a section entitled ""How to Use This Book."" He writes that it is intended for both independent reading and reference as well as for use in courses on scientific method and the philosophy of science. It suits a variety of purposes from introductory to advanced levels. Philosophy of Science is a versatile, informative, and useful text that will benefit professors, researchers, and students in a variety of disciplines, ranging from the behavioral and biological sciences to the physical sciences.

Empirical Justification

Download Empirical Justification PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9400945264
Total Pages : 272 pages
Book Rating : 4.4/5 (9 download)

DOWNLOAD NOW!


Book Synopsis Empirical Justification by : P.K. Moser

Download or read book Empirical Justification written by P.K. Moser and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Broadly speaking, this is a book about truth and the criteria thereof. Thus it is, in a sense, a book about justification and rationality. But it does not purport to be about the notion of justification or the notion of rationality. For the assumption that there is just one notion of justification, or just one notion of rationality, is, as the book explains, very misleading. Justification and rationality come in various kinds. And to that extent, at least, we should recognize a variety of notions of justification and rationality. This, at any rate, is one of the morals of Chapter VI. This book, in Chapters I-V, is mainly concerned with the kind of justification and rationality characteristic of a truth-seeker, specifically a seeker of truth about the world impinging upon the senses: the so-called empirical world. Hence the book's title. But since the prominent contemporary approaches to empirical justification are many and varied, so also are the epistemological issues taken up in the following chapters. For instance, there will be questions about so-called coherence and its role, if any, in empirical justification. And there will be questions about social consensus (whatever it is) and its significance, or the lack thereof, to empirical justification. Furthermore, the perennial question of whether, and if so how, empirical knowledge has so-called founda tions will be given special attention.

The Dedcutive Justification of Scientific Theories as Refutation of Known Alternatives

Download The Dedcutive Justification of Scientific Theories as Refutation of Known Alternatives PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 250 pages
Book Rating : 4.:/5 (198 download)

DOWNLOAD NOW!


Book Synopsis The Dedcutive Justification of Scientific Theories as Refutation of Known Alternatives by : Christopher Carter Humphrey

Download or read book The Dedcutive Justification of Scientific Theories as Refutation of Known Alternatives written by Christopher Carter Humphrey and published by . This book was released on 1967 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Reproducibility and Replicability in Science

Download Reproducibility and Replicability in Science PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309486165
Total Pages : 257 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!


Book Synopsis Reproducibility and Replicability in Science by : National Academies of Sciences, Engineering, and Medicine

Download or read book Reproducibility and Replicability in Science written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-10-20 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.

The Justification of Scientific Change

Download The Justification of Scientific Change PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 9789027701817
Total Pages : 122 pages
Book Rating : 4.7/5 (18 download)

DOWNLOAD NOW!


Book Synopsis The Justification of Scientific Change by : C.R. Kordig

Download or read book The Justification of Scientific Change written by C.R. Kordig and published by Springer. This book was released on 1975-04-30 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book I discuss the justification of scientific change and argue that it rests on different sorts of invariance. Against this background I con sider notions of observation, meaning, and regulative standards. My position is in opposition to some widely influential and current views. Revolutionary new ideas concerning the philosophy of science have recently been advanced by Feyerabend, Hanson, Kuhn, Toulmin, and others. There are differences among their views and each in some respect differs from the others. It is, however, not the differences, but rather the similarities that are of primary concern to me here. The claim that there are pervasive presuppositions fundamental to scientific in vestigations seems to be essential to the views of these men. Each would further hold that transitions from one scientific tradition to another force radical changes in what is observed, in the meanings of the terms employed, and in the metastandards involved. They would claim that total replace ment, not reduction, is what does, and should, occur during scientific revolutions. I argue that the proposed arguments for radical observational variance, for radical meaning variance, and for radical variance of regulative standards with respect to scientific transitions all fail. I further argue that these positions are in themselves implausible and methodologically undesirable. I sketch an account of the rationale of scientific change which preserves the merits and avoids the shortcomings of the approach of radical meaning variance theorists.

The justification of scientific change

Download The justification of scientific change PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 133 pages
Book Rating : 4.:/5 (462 download)

DOWNLOAD NOW!


Book Synopsis The justification of scientific change by : Carl R. Kordig

Download or read book The justification of scientific change written by Carl R. Kordig and published by . This book was released on 1971 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Justification of Induction

Download The Justification of Induction PDF Online Free

Author :
Publisher : [London ; New York] : Oxford University Press
ISBN 13 :
Total Pages : 214 pages
Book Rating : 4.F/5 ( download)

DOWNLOAD NOW!


Book Synopsis The Justification of Induction by : Richard Swinburne

Download or read book The Justification of Induction written by Richard Swinburne and published by [London ; New York] : Oxford University Press. This book was released on 1974 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Racism

Download Racism PDF Online Free

Author :
Publisher : Princeton University Press
ISBN 13 : 1400873673
Total Pages : 228 pages
Book Rating : 4.4/5 (8 download)

DOWNLOAD NOW!


Book Synopsis Racism by : George M. Fredrickson

Download or read book Racism written by George M. Fredrickson and published by Princeton University Press. This book was released on 2015-09-15 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are antisemitism and white supremacy manifestations of a general phenomenon? Why didn't racism appear in Europe before the fourteenth century, and why did it flourish as never before in the eighteenth and nineteenth centuries? Why did the twentieth century see institutionalized racism in its most extreme forms? Why are egalitarian societies particularly susceptible to virulent racism? What do apartheid South Africa, Nazi Germany, and the American South under Jim Crow have in common? How did the Holocaust advance civil rights in the United States? With a rare blend of learning, economy, and cutting insight, George Fredrickson surveys the history of Western racism from its emergence in the late Middle Ages to the present. Beginning with the medieval antisemitism that put Jews beyond the pale of humanity, he traces the spread of racist thinking in the wake of European expansionism and the beginnings of the African slave trade. And he examines how the Enlightenment and nineteenth-century romantic nationalism created a new intellectual context for debates over slavery and Jewish emancipation. Fredrickson then makes the first sustained comparison between the color-coded racism of nineteenth-century America and the antisemitic racism that appeared in Germany around the same time. He finds similarity enough to justify the common label but also major differences in the nature and functions of the stereotypes invoked. The book concludes with a provocative account of the rise and decline of the twentieth century's overtly racist regimes--the Jim Crow South, Nazi Germany, and apartheid South Africa--in the context of world historical developments. This illuminating work is the first to treat racism across such a sweep of history and geography. It is distinguished not only by its original comparison of modern racism's two most significant varieties--white supremacy and antisemitism--but also by its eminent readability.

Karl Popper's Philosophy of Science

Download Karl Popper's Philosophy of Science PDF Online Free

Author :
Publisher : Routledge
ISBN 13 : 1134182953
Total Pages : 154 pages
Book Rating : 4.1/5 (341 download)

DOWNLOAD NOW!


Book Synopsis Karl Popper's Philosophy of Science by : Stefano Gattei

Download or read book Karl Popper's Philosophy of Science written by Stefano Gattei and published by Routledge. This book was released on 2008-10-16 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rectifying misrepresentations of Popperian thought with a historical approach to Popper’s philosophy, Gattei reconstructs the logic of Popper’s development to show how one problem and its tentative solution led to a new problem.

A Theory of Epistemic Justification

Download A Theory of Epistemic Justification PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402095678
Total Pages : 222 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!


Book Synopsis A Theory of Epistemic Justification by : J. Leplin

Download or read book A Theory of Epistemic Justification written by J. Leplin and published by Springer Science & Business Media. This book was released on 2009-02-28 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: One goal of epistemology is to refute the skeptic. Another, with an equally dist- guished if briefer pedigree, is to make sense of science as a knowledge-acquiring enterprise. The goals are incompatible, in that the latter presupposes that the skeptic is wrong. The incompatibility is not strict. One could have both goals, conditi- ing the latter upon success at the former. In fact, however, epistemologies aimed at the skeptic tend not to get anywhere near science. They’ve got all they can handle guring out how we can know we have hands. I come to epistemology from the philosophy of science, my original interest in which was epistemological. Philosophers of science are concerned with epistemic justi cation, but their question about it is how far it extends. They take justi cation to be unproblematic at the level of ordinary experience; their worries begin with the interpretation of experience as evidence for theory. They are interested in the scope of scienti c knowledge. Having taken a position on this question (1997), - guing that justi cation extends to theoretical hypotheses, I came to wonder about the nature of justi cation generally. This is not a belated discovery of the skeptical problem or a reconsideration of what I took to be unproblematic. It is simply an interest in the possibility of locating epistemic advance in science within a broader understanding of the nature of epistemic justi cation. Now that I know that just- cation extends to theory, I am taking a step back and asking what justi cation is.