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Respiratory Flows In The Pulmonary Acinus
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Book Synopsis Respiratory Flows in the Pulmonary Acinus by : Josué Sznitman
Download or read book Respiratory Flows in the Pulmonary Acinus written by Josué Sznitman and published by Sudwestdeutscher Verlag Fur Hochschulschriften AG. This book was released on 2009 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pulmonary acinus, known as the gas exchange region of the lung, encompasses the complex of millions of sub-millimeter alveoli and may represent a potential host for pulmonary complications and diseases. These health disorders may require the inhalation of therapeutic drugs typically administered in the form of aerosolized particles. Both a precise understanding of the mechanisms leading to particle deposition as well as the need to target aerosols to specific pulmonary sites, remain ongoing challenges and depend directly on the fluid dynamics in the lung, and specifically on the microflows present in the acinar region. These considerations call not only for a deepening of our understanding of the fluid mechanics pertinent to the acinar region of the lung, but also, for the potential development of novel strategies towards improved and enhanced particle deposition inside the lung. The present thesis, which lies at the interface between engineering and medicine, is concerned with the role of convective respiratory flows in the acinar region of the lung, in conjunction with the transport and deposition of inhaled particles.
Book Synopsis Respiratory Flows in the Pulmonary Acinus and Insights on the Control of Alveolar Flows by : Josué Sznitman
Download or read book Respiratory Flows in the Pulmonary Acinus and Insights on the Control of Alveolar Flows written by Josué Sznitman and published by . This book was released on 2008 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lung Development by : Claude Gaultier
Download or read book Lung Development written by Claude Gaultier and published by Springer. This book was released on 2013-05-27 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge about the mechanisms of lung development has been growing rapidly, especially with regard to cellular and molecular aspects of growth and differentiation. This authoritative international volume reviews key aspects of lung development in health and disease by providing a comprehensive review of the complex series of cellular and molecular interactions required for lung development. It covers such topics as pulmonary hypoplasia, effects of malnutrition, and pulmaonary angiogenesis. An indispensable reference for all those involved in studying or treating lung disease in neonates and children, the book offers a unique view of the development of this essential organ.
Book Synopsis Structure-Function Relationships in Various Respiratory Systems by : Kazuhiro Yamaguchi
Download or read book Structure-Function Relationships in Various Respiratory Systems written by Kazuhiro Yamaguchi and published by Springer Nature. This book was released on 2020-07-31 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elucidates the morphological backgrounds of various functional parameters of the human respiratory system, including the respiratory control system, dynamics of the upper and lower airways, gas transport and mixing in the lower airways, gas exchange in the acinus, and gas transfer through the alveolar wall. Presenting the latest findings on the interrelationships between morphology and physiology in the respiratory system, the book’s goal is to provide a foundation for further exploring structure-function relationships in various respiratory systems, and to improve both the quality of basic science, and that of clinical medicine targeting the human respiratory system. Edited and written by internationally recognized experts, Structure-Function Relationships in Various Respiratory Systems offers a valuable asset for all physicians and researchers engaging in clinical, physiological, or morphological work in the field of respiration. Moreover, it provides a practical guide for physicians, helping them make more precise pathophysiological decisions concerning patients with various types of lung disease, and will be of interest to respiratory physiologists and respiratory morphologists.
Book Synopsis Pulmonary Function Indices in Critical Care Patients by : Josef X. Brunner
Download or read book Pulmonary Function Indices in Critical Care Patients written by Josef X. Brunner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Respiration is a unique topic among various subdisciplines of physiology. Physiolo gists and clinicians are now able to communicate quantitative functional properties of lung mechanics and gas exchange in the language of the engineer, physicist and mathematician. This is largely due to intensive and stimulating work during the last decades of brilliant minds in a handful of excellent schools in the international family of physiologists. Among these founders of respiratory physiology are a number of clinicians, and they have. taken significant ,part both in shaping the theoretical knowledge to clinical applicability and developing technical devices for diagnosis and therapy in pulmonology. However, the theory behind the evaluation of measure ments, and their interpretation in terms of clinical function tests, is so confusingly complex that the ordinary physician, not specifically trained in respiratory physiol ogy, finds himself unable to critically apply these techniques. We, therefore, need descriptions of respiratory physiology and of its clinical application presented in the language of the clinician. And that is what this book is meant to be. Written by an expert in electrical and biomedical engineering, and by an expert in intensive care medicine, this text constitutes an "operational manual" of clinical respiratory physiology. It does not intend to be another textbook of basic respiratory physiology or pathophysiology. This book not only addresses practical clinicians, particularly those of intensive care medicine, by describing the essentials of clinically relevant respiratory knowledge.
Author :United States. Public Health Service. Office of the Surgeon General Publisher : ISBN 13 : Total Pages :728 pages Book Rating :4.:/5 (318 download)
Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Respiratory Physiology by : H. K. Chang
Download or read book Respiratory Physiology written by H. K. Chang and published by Marcel Dekker. This book was released on 1989 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference applies a unique analytical approach for a comprehensive treatment of topics in respiratory physiology: flow and resistance in the airways; the morphometry of the lung; transport and mixing of inspired gas; the lung's structural elements; major determinants of pulmonary gas exchange; the pulmonary vasculature's mechanical behavior; lung fluid balance and solute transport; and models of control of breathing. Also discusses well-established lung function tests for airway resistance, maximal expiration, and diffusing capacity; examines clinical indices; and considers common pathological conditions. Annotation(c) 2003 Book News, Inc., Portland, OR (booknews.com)
Book Synopsis Study of Airflow and Particle Transport in Acinar Airways of the Human Lung by : Haribalan Kumar
Download or read book Study of Airflow and Particle Transport in Acinar Airways of the Human Lung written by Haribalan Kumar and published by . This book was released on 2011 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this work, airflow and particle transport are studied using mathematical and image-based models of pulmonary acinus. Numerical results predict that airflow in the presence of wall motion in a three-dimensional honey-comb like geometry is characterized by the presence of a recirculation region within the alveolar cavity and a weak entraining flow between alveolar duct and cavity. Alveolar flow in distal generations is characterized by higher alveolar flow rates, larger entrainment of ductal flow and absence of recirculatory flow inside alveoli. The study of transport constitutes assessment of mixing visualized by the tracking of massless particles and the study of transport and deposition of aerosols. The phenomenon of steady streaming is found to hold the key to the origin of kinematic mixing in the alveolus, the alveolar mouth and the alveolated duct. This mechanism provides the explanation for observed folding of material lines and increases in material surface area, and has no bearing on whether the geometry is expanding or if flow separates within the cavity or not. Streaming results in non-zero drift of particles between the beginning and end of a breathing cycle. Based on flow conditions and resultant convective mixing measures, we conclude that significant convective mixing in the duct and within an alveolus could originate only in the first few generations of the acinar tree as a result of non-zero inertia, flow asymmetry and large KC number. Evidence of streaming and related Lagrangian drift is also observed in image-based acinar models. Finally, particle deposition calculations are performed on the models of pulmonary acinus considered in this study.
Book Synopsis Oxford Textbook of Critical Care by : Webb
Download or read book Oxford Textbook of Critical Care written by Webb and published by Oxford University Press. This book was released on 2020-01-10 with total page 1961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.
Book Synopsis Fetal and Neonatal Lung Development by : Alan H. Jobe
Download or read book Fetal and Neonatal Lung Development written by Alan H. Jobe and published by Cambridge University Press. This book was released on 2016-04-18 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development and is designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book covers genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going in order to improve outcomes for patients with common and rare lung diseases.
Book Synopsis The Oxford Handbook of Evolutionary Medicine by : Martin Brüne
Download or read book The Oxford Handbook of Evolutionary Medicine written by Martin Brüne and published by Oxford University Press. This book was released on 2019-01-31 with total page 967 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicine is grounded in the natural sciences, where biology stands out with regard to our understanding of human physiology and the conditions that cause dysfunction. Ironically though, evolutionary biology is a relatively disregarded field. One reason for this omission is that evolution is deemed a slow process. Indeed, the macroanatomical features of our species have changed very little in the last 300,000 years. A more detailed look, however, reveals that novel ecological contingencies, partly in relation to cultural evolution, have brought about subtle changes pertaining to metabolism and immunology, including adaptations to dietary innovations, as well as adaptations to the exposure to novel pathogens. Rapid pathogen evolution and evolution of cancer cells cause major problems for the immune system. Moreover, many adaptations to past ecologies have actually turned into risk factors for somatic disease and psychological disorder in our modern worlds (i.e. mismatch), among which epidemics of autoimmune diseases, cardiovascular diseases, diabetes and obesity, as well as several forms of cancer stand out. One could add depression, anxiety, and other psychiatric conditions to the list. The Oxford Handbook of Evolutionary Medicine is a compilation of up-to-date insights into the evolutionary history of ourselves as a species, exploring how and why our evolved design may convey vulnerability to disease. Written in a classic textbook style emphasising physiology and pathophysiology of all major organ systems, the Oxford Handbook of Evolutionary Medicine is valuable reading for students as well as scholars in the fields of medicine, biology, anthropology and psychology.
Download or read book Capnography written by J. S. Gravenstein and published by Cambridge University Press. This book was released on 2011-03-17 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years capnography has gained a foothold in the medical field and is fast becoming a standard of care in anaesthesiology and critical care medicine. In addition, newer applications have emerged which have expanded the utility of capnographs in a number of medical disciplines. This new edition of the definitive text on capnography reviews every aspect of this valuable diagnostic technique. An introductory section summarises the basic physiology of carbon dioxide generation and transport in the body. A technical section describes how the instruments work, and a comprehensive clinical section reviews the use of capnography to diagnose a wide range of clinical disorders. Edited by the world experts in the technique, and with over 40 specialist contributors, Capnography, second edition, is the most comprehensive review available on the application of capnography in health care.
Author :Peter Slinger, MD, FRCPC Publisher :Springer Science & Business Media ISBN 13 :1441901833 Total Pages :718 pages Book Rating :4.4/5 (419 download)
Book Synopsis Principles and Practice of Anesthesia for Thoracic Surgery by : Peter Slinger, MD, FRCPC
Download or read book Principles and Practice of Anesthesia for Thoracic Surgery written by Peter Slinger, MD, FRCPC and published by Springer Science & Business Media. This book was released on 2011-07-12 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Practice of Anesthesia for Thoracic Surgery will serve as an updated comprehensive review covering not only the recent advances, but also topics that haven't been covered in previously published texts: extracorporeal ventilatory support, new advances in chest imaging modalities, lung isolation with a difficult airway, pulmonary thrombo-endarterectomy, and chronic post-thoracotomy pain. Additionally, the book features clinical case discussions at the end of each clinical chapter as well as tables comprising detailed anesthetic management.
Book Synopsis Lung, Pleura, and Mediastinum by : Liang-Che Tao
Download or read book Lung, Pleura, and Mediastinum written by Liang-Che Tao and published by Igaku-Shoin Medical Publishers. This book was released on 1988 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fundamentals of Anaesthesia by : Colin Pinnock
Download or read book Fundamentals of Anaesthesia written by Colin Pinnock and published by Cambridge University Press. This book was released on 2002-12 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.
Book Synopsis Scott-Brown's Otorhinolaryngology, Head and Neck Surgery by : Michael Gleeson
Download or read book Scott-Brown's Otorhinolaryngology, Head and Neck Surgery written by Michael Gleeson and published by Hodder Education. This book was released on 2008 with total page 1368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition has been fully updated by an international team of editors and contributors and is highly illustrated in color throughout. The majority of the chapters are evidence-based and each contains useful features including key points, best clinical practice guidelines, details of the search strategies used to prepare the material, and suggestions for future research.
Book Synopsis Computational Fluid and Particle Dynamics in the Human Respiratory System by : Jiyuan Tu
Download or read book Computational Fluid and Particle Dynamics in the Human Respiratory System written by Jiyuan Tu and published by Springer Science & Business Media. This book was released on 2012-09-18 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditional research methodologies in the human respiratory system have always been challenging due to their invasive nature. Recent advances in medical imaging and computational fluid dynamics (CFD) have accelerated this research. This book compiles and details recent advances in the modelling of the respiratory system for researchers, engineers, scientists, and health practitioners. It breaks down the complexities of this field and provides both students and scientists with an introduction and starting point to the physiology of the respiratory system, fluid dynamics and advanced CFD modeling tools. In addition to a brief introduction to the physics of the respiratory system and an overview of computational methods, the book contains best-practice guidelines for establishing high-quality computational models and simulations. Inspiration for new simulations can be gained through innovative case studies as well as hands-on practice using pre-made computational code. Last but not least, students and researchers are presented the latest biomedical research activities, and the computational visualizations will enhance their understanding of physiological functions of the respiratory system.
