Protein Nanoparticle Interactions

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Protein-Nanoparticle Interactions

Author : Masoud Rahman
Publisher : Springer Science & Business Media
ISBN 13 : 3642375553
Total Pages : 95 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Protein-Nanoparticle Interactions by : Masoud Rahman

Download or read book Protein-Nanoparticle Interactions written by Masoud Rahman and published by Springer Science & Business Media. This book was released on 2013-06-24 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a “biological identity” to their surfaces (referred to as a “corona”), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called “bio-nano interface,” has been very rarely studied in detail to date, though the interest in this topic is rapidly growing. In this book, the importance of the physiochemical characteristics of nanoparticles for the properties of the protein corona is discussed in detail, followed by comprehensive descriptions of the methods for assessing the protein-nanoparticle interactions. The advantages and limitations of available corona evaluation methods (e.g. spectroscopy methods, mass spectrometry, nuclear magnetic resonance, electron microscopy, X-ray crystallography, and differential centrifugal sedimentation) are examined in detail, followed by a discussion of the possibilities for enhancing the current methods and a call for new techniques. Moreover, the advantages and disadvantages of protein-nanoparticle interaction phenomena are explored and discussed, with a focus on the biological impacts.

NanoparticleProtein Corona

Author : Ashutosh Kumar
Publisher : Royal Society of Chemistry
ISBN 13 : 1788018532
Total Pages : 310 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis NanoparticleProtein Corona by : Ashutosh Kumar

Download or read book NanoparticleProtein Corona written by Ashutosh Kumar and published by Royal Society of Chemistry. This book was released on 2019-07-26 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticles have numerous biomedical applications including drug delivery, bone implants and imaging. A protein corona is formed when proteins existing in a biological system cover the nanoparticle surface. The formation of a nanoparticle–protein corona, changes the behaviour of the nanoparticle, resulting in new biological characteristics and influencing the circulation lifetime, accumulation, toxicity, cellular uptake and agglomeration. This book provides a detailed understanding of nanoparticle–protein corona formation, its biological significance and the factors that govern the formation of coronas. It also explains the impact of nanoparticle–protein interactions on biological assays, ecotoxicity studies and proteomics research. It will be of interest to researchers studying the application of nanoparticles as well as toxicologists and pharmaceutical chemists.

Protein-Protein Interaction Assays

Author : Mahmood-Ur-Rahman Ansari
Publisher : BoD – Books on Demand
ISBN 13 : 1789233909
Total Pages : 91 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Protein-Protein Interaction Assays by : Mahmood-Ur-Rahman Ansari

Download or read book Protein-Protein Interaction Assays written by Mahmood-Ur-Rahman Ansari and published by BoD – Books on Demand. This book was released on 2018-07-18 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters in this book are written by a team of well-reputed international researchers. The objective is to provide advanced and updated information related to protein-protein interactions. I hope the methods, resources and approaches described here will enhance the available knowledge of the reader significantly.

Handbook of Immunological Properties of Engineered Nanomaterials

Author : Marina Dobrovolskaia
Publisher : World Scientific
ISBN 13 : 9814390259
Total Pages : 721 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Handbook of Immunological Properties of Engineered Nanomaterials by : Marina Dobrovolskaia

Download or read book Handbook of Immunological Properties of Engineered Nanomaterials written by Marina Dobrovolskaia and published by World Scientific. This book was released on 2013 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.

Bioprospecting of Enzymes in Industry, Healthcare and Sustainable Environment

Author : Hrudayanath Thatoi
Publisher : Springer Nature
ISBN 13 : 9813341955
Total Pages : 408 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Bioprospecting of Enzymes in Industry, Healthcare and Sustainable Environment by : Hrudayanath Thatoi

Download or read book Bioprospecting of Enzymes in Industry, Healthcare and Sustainable Environment written by Hrudayanath Thatoi and published by Springer Nature. This book was released on 2021-01-23 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid urbanization and industrialization of developing countries across the globe have necessitated for substantial resource utilization and development in the areas of Healthcare, Environment, and Renewable energy. In this context ,this resourceful book serves as a definitive source of information for the recent developments in application of microbial enzymes in various sectors. It covers applications in fermentation processes and their products, extraction and utilisation of enzymes from various sources and their application in health and biomass conversion for production of value added products. Different chapters discuss various areas of bioprospecting in enzyme technology, and describe why these are the mainstays for industrial production of value added products. The rich compilation of the cutting-edge advances and applications of the modern industrial based techniques hold feasible solutions for a range of current issues in enzyme technology. This book will be of particular interest for scientists, academicians, technical resource persons, engineers and members of industry. Undergraduate and graduate students pursuing courses in the area of industrial biotechnology will find the information in the book valuable. General readers having interest towards biofuels, enzyme technology, fermented food and value added products, phytochemicals and phytopharmaceutical products will also find the book appealing. Readers will discover modern concepts of enzymatic bioprocess technology for production of therapeutics and industrial value added products.

Colloids for Nanobiotechnology

Author : Wolfgang Parak
Publisher : Elsevier
ISBN 13 : 0081028288
Total Pages : 398 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Colloids for Nanobiotechnology by : Wolfgang Parak

Download or read book Colloids for Nanobiotechnology written by Wolfgang Parak and published by Elsevier. This book was released on 2020-05-13 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colloids for Nanobiotechnology: Synthesis, Characterization and Potential Applications, Volume 17, offers a range of perspectives on emerging nano-inspired colloidal applications. With an emphasis on biomedical and environmental opportunities and challenges, the book outlines how nanotechnology is being used to increase the uses and impact of colloid science. Nanotechnology offers new horizons for colloidal research and synthesis routes that allow for the production of highly reproducible and defined materials. This book presents new characterization methods and a fundamental understanding of basic physicochemical, physical and chemical properties. Explores the use of nanotechnology in enhancing colloidal characterization techniques Explains how colloids are being used in a range of nanomedical applications Demonstrates how nanotechnology is being used to create more efficient colloidal synthesis techniques

Nanoparticle–Protein Corona

Author : Ashutosh Kumar
Publisher : Royal Society of Chemistry
ISBN 13 : 1788013913
Total Pages : 310 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Nanoparticle–Protein Corona by : Ashutosh Kumar

Download or read book Nanoparticle–Protein Corona written by Ashutosh Kumar and published by Royal Society of Chemistry. This book was released on 2019-08-02 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticles have numerous biomedical applications including drug delivery, bone implants and imaging. A protein corona is formed when proteins existing in a biological system cover the nanoparticle surface. The formation of a nanoparticle–protein corona, changes the behaviour of the nanoparticle, resulting in new biological characteristics and influencing the circulation lifetime, accumulation, toxicity, cellular uptake and agglomeration. This book provides a detailed understanding of nanoparticle–protein corona formation, its biological significance and the factors that govern the formation of coronas. It also explains the impact of nanoparticle–protein interactions on biological assays, ecotoxicity studies and proteomics research. It will be of interest to researchers studying the application of nanoparticles as well as toxicologists and pharmaceutical chemists.

An Introduction to Tissue-Biomaterial Interactions

Author : Kay C. Dee
Publisher : John Wiley & Sons
ISBN 13 : 0471461121
Total Pages : 250 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis An Introduction to Tissue-Biomaterial Interactions by : Kay C. Dee

Download or read book An Introduction to Tissue-Biomaterial Interactions written by Kay C. Dee and published by John Wiley & Sons. This book was released on 2003-04-14 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Tissue-Biomaterial Interactions acquaints an undergraduate audience with the fundamental biological processes that influence these sophisticated, cutting-edge procedures. Chapters one through three provide more detail about the molecular-level events that happen at the tissue-implant interface, while chapters four through ten explore selected material, biological, and physiological consequences of these events. The importance of the body’s wound-healing response is emphasized throughout. Specific topics covered include:Structure and properties of biomaterials Proteins Protein-surface interactions Blood-biomaterial interactions Inflammation and infection The immune system Biomaterial responses to implantation Biomaterial surface engineering Intimal hyperplasia and osseointegration as examples of tissue-biomaterial interactions The text also provides extensive coverage of the three pertinent interfaces between the body and the biomaterial, between the body and the living cells, and between the cells and the biomaterial that are critical in the development of tissue-engineered products that incorporate living cells within a biomaterial matrix. Ideal for a one-semester, biomedical engineering course, An Introduction to Tissue-Biomaterial Interactions provides a solid framework for understanding today’s and tomorrow’s implantable biomedical devices.

Nanoparticles and the Immune System

Author : Diana Boraschi
Publisher : Academic Press
ISBN 13 : 0124079210
Total Pages : 138 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Nanoparticles and the Immune System by : Diana Boraschi

Download or read book Nanoparticles and the Immune System written by Diana Boraschi and published by Academic Press. This book was released on 2013-11-29 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticles and the Immune System provides a reference text for toxicologists, materials scientists and regulators and covers the key issues of interaction of nanomaterials with the immune system. The book discusses several issues that toxicologists and regulators need to know: identification of endpoints that are relevant for assessing hazard, evaluating impact on immunologically frail populations, and how to evaluate chronic/cumulative effects. In addition, the book addresses the possibility of turning the immunomodulating properties of certain nanomaterials to our advantage for amplifying immune responses in certain diseases or preventive strategies (e.g. vaccination). Identifies endpoints relevant for assessing hazardous situations, evaluating the impact on immunologically frail populations and how to gauge chronic/cumulative effects Raises the awareness of the importance of knowing the effects of the new nanomaterials on our immune system

Microbial Interactions at Nanobiotechnology Interfaces

Author : R. Navanietha Krishnaraj
Publisher : John Wiley & Sons
ISBN 13 : 1119617170
Total Pages : 416 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Microbial Interactions at Nanobiotechnology Interfaces by : R. Navanietha Krishnaraj

Download or read book Microbial Interactions at Nanobiotechnology Interfaces written by R. Navanietha Krishnaraj and published by John Wiley & Sons. This book was released on 2021-10-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: MICROBIAL INTERACTIONS AT NANOBIOTECHNOLOGY INTERFACES This book covers a wide range of topics including synthesis of nanomaterials with specific size, shape, and properties, structure-function relationships, tailoring the surface of nanomaterials for improving the properties, interaction of nanomaterials with proteins/microorganism/eukaryotic cells, and applications in different sectors. This book also provides a strong foundation for researchers who are interested to venture into developing functionalized nanomaterials for any biological applications in their research. Practical concepts such as modelling nanomaterials, and simulating the molecular interactions with biomolecules, transcriptomic or genomic approaches, advanced imaging techniques to investigate the functionalization of nanomaterials/interaction of nanomaterials with biomolecules and microorganisms are some of the chapters that offer significant benefits to the researchers.

Nano-Enabled Medical Applications

Author : Lajos P. Balogh
Publisher : CRC Press
ISBN 13 : 0429677898
Total Pages : 0 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Nano-Enabled Medical Applications by : Lajos P. Balogh

Download or read book Nano-Enabled Medical Applications written by Lajos P. Balogh and published by CRC Press. This book was released on 2020-11-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the second in a series presenting articles that received the most citations in recent years in nanomedicine. The series is edited by, a prominent nanotechnology researcher and editor-in-chief of Precision Nanomedicine. The theme of the second volume is about nano-enabled medical applications. The 19 articles collected here have already acquired more than 12,500 citations highlighting the importance and professional recognition of the work of these scientists in nanomedicine. The content includes the general overview of the field and a wide variety of applications that have been impossible without nanoscience and nanotechnology.

High Performance Computing in Science and Engineering ' 17

Author : Wolfgang E. Nagel
Publisher : Springer
ISBN 13 : 3319683942
Total Pages : 529 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis High Performance Computing in Science and Engineering ' 17 by : Wolfgang E. Nagel

Download or read book High Performance Computing in Science and Engineering ' 17 written by Wolfgang E. Nagel and published by Springer. This book was released on 2018-02-16 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the state-of-the-art in supercomputer simulation. It includes the latest findings from leading researchers using systems from the High Performance Computing Center Stuttgart (HLRS) in 2017. The reports cover all fields of computational science and engineering ranging from CFD to computational physics and from chemistry to computer science with a special emphasis on industrially relevant applications. Presenting findings of one of Europe’s leading systems, this volume covers a wide variety of applications that deliver a high level of sustained performance.The book covers the main methods in high-performance computing. Its outstanding results in achieving the best performance for production codes are of particular interest for both scientists and engineers. The book comes with a wealth of color illustrations and tables of results.

Concepts and Design of Materials Nanoarchitectonics

Author : Omar Azzaroni
Publisher : Royal Society of Chemistry
ISBN 13 : 1788019628
Total Pages : 521 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Concepts and Design of Materials Nanoarchitectonics by : Omar Azzaroni

Download or read book Concepts and Design of Materials Nanoarchitectonics written by Omar Azzaroni and published by Royal Society of Chemistry. This book was released on 2022-02-09 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of nanoarchitechtonics was introduced to describe the correct manipulation of nanoscale materials in the creation of nano-devices and applications. Nanoarchitectonics has begun to spread into many fields including nanostructured materials synthesis, supramolecular assembly, nanoscale structural fabrications, materials hybridizations, materials and structures for energy and environmental sciences, device and physical application, and bio- and medical applications. Following on from the 2012 title Manipulation of Nanoscale Materials, Concepts and Design of Materials Nanoarchitectonics covers the introductory features underlying the field, presenting a unifying overview of the theoretical aspects and emerging applications that are changing the capability to understand and design advanced functional materials. Edited by pioneers of the field, this book will appeal to researchers working in nanoscience, materials science, supramolecular chemistry, physical chemistry and organic chemistry, as well as graduate students in these areas.

Characterization of Pharmaceutical Nano- and Microsystems

Author : Leena Peltonen
Publisher : John Wiley & Sons
ISBN 13 : 1119414040
Total Pages : 410 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Characterization of Pharmaceutical Nano- and Microsystems by : Leena Peltonen

Download or read book Characterization of Pharmaceutical Nano- and Microsystems written by Leena Peltonen and published by John Wiley & Sons. This book was released on 2020-12-21 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale. The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker. Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines. Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics: An introduction to the analytical tools applied to determine particle size, morphology, and shape Common chemical approaches to drug system characterization A description of solid-state characterization of drug systems Drug release and permeation studies Toxicity and safety issues The interaction of drug particles with cells Perfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.

Unraveling the Safety Profile of Nanoscale Particles and Materials

Author : Andreia Ferreira de Castro Gomes
Publisher : BoD – Books on Demand
ISBN 13 : 9535139398
Total Pages : 174 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Unraveling the Safety Profile of Nanoscale Particles and Materials by : Andreia Ferreira de Castro Gomes

Download or read book Unraveling the Safety Profile of Nanoscale Particles and Materials written by Andreia Ferreira de Castro Gomes and published by BoD – Books on Demand. This book was released on 2018-03-21 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: As nanomaterials become increasingly present in our daily lives, pertinent questions regarding their safety arise. Nanomaterial risk assessment, as in other areas, directs much of the effort worldwide in defining guidelines that may be translated into national or international directives. Nanomaterials encompass different entities, from nanoparticles to nanostructured materials, with specific effects over cells, tissues, organisms and ecosystems depending on their biophysical characteristics. Such interactions will directly affect the impact of novel nanotechnologies. This book aims to provide the reader with a comprehensive overview of the current state of the art in nanotoxicology, featuring the most important developments and critical issues regarding the use of and exposure to nanoparticles.

Non-covalent Interactions In Proteins

Author : Karshikoff Andrey
Publisher : World Scientific
ISBN 13 : 191129928X
Total Pages : 348 pages
Book Rating : 4.9/5 (112 download)

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Book Synopsis Non-covalent Interactions In Proteins by : Karshikoff Andrey

Download or read book Non-covalent Interactions In Proteins written by Karshikoff Andrey and published by World Scientific. This book was released on 2006-11-23 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although textbooks on the physics of condensed matter consider non-covalent interactions in detail, their application for analysis of protein properties is often poorly presented or omitted. On the other hand, books on biochemistry, molecular modeling or molecular simulation introduce these interactions in the context of the corresponding topic, which sometimes results in superficial explanations of their nature. This book succeeds in uniting comprehensive considerations of non-covalent interactions with the specificity of their application in protein sciences.The ideal aid for students of physics or chemistry, with interests in biology and biophysics, the book can also be useful for students of biology, biochemistry, or biomedicine who want to extend their knowledge of how protein properties are described at the molecular level./a

Selected Progresses in Modern Physics

Author : Soumitra Sengupta
Publisher : Springer Nature
ISBN 13 : 9811651418
Total Pages : 423 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Selected Progresses in Modern Physics by : Soumitra Sengupta

Download or read book Selected Progresses in Modern Physics written by Soumitra Sengupta and published by Springer Nature. This book was released on 2022-01-01 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents peer-reviewed articles from the 1st International Conference on Trends in Modern Physics (TiMP 2021) held at Assam Don Bosco University in Guwahati, India, between February 26 and 27, 2021. This conference was the 3rd in a series of annual conferences of the Department of Physics, ADBU, with the 1st and 2nd being national conferences. The conference was jointly organized by the Department of Physics, ADBU, and the Indian Association of Physics Teachers (IAPT) to promote greater synergy between thematic areas of astrophysics and cosmology, plasma physics, material and nanophysics, nuclear physics, and particle physics