Handbook Of Immunological Properties Of Engineered Nanomaterials

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Handbook Of Immunological Properties Of Engineered Nanomaterials (Second Edition) (In 3 Volumes)

Author : Dobrovolskaia Marina A
Publisher : World Scientific
ISBN 13 : 9814699187
Total Pages : 1184 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Handbook Of Immunological Properties Of Engineered Nanomaterials (Second Edition) (In 3 Volumes) by : Dobrovolskaia Marina A

Download or read book Handbook Of Immunological Properties Of Engineered Nanomaterials (Second Edition) (In 3 Volumes) written by Dobrovolskaia Marina A and published by World Scientific. This book was released on 2016-01-28 with total page 1184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book provides comprehensive overview of the field of immunology related to engineered nanomaterials used for biomedical applications. It contains literature review, case studies and protocols. The book can serve as a source of information about nanoimmunotoxicology for both junior scientists and experts in the field. The authors have more than 10 years of experience with preclinical characterization of engineered nanomaterials used for medical applications, and they share their experience with the readers. In addition, the international team of experts in the field provides the opinion and share the expertise on individual topics related to nanoparticle physicochemical characterization, hematocompatibility, and effects on the immune cell function . The second edition contains updated chapters from the first edition plus new chapters covering areas of tumor immunology, nanoparticle interaction with lymphatic system, mathematical modeling of protein corona, utilization of nanoparticles for the delivery of antiviral drugs, extensive analysis of nanoparticle anti-inflammatory and immunosuppressive properties, novel ways of protecting therapeutic nanoparticles from the immune recognition, as well as case studies regarding nanoparticle sterilization, complement activation, protein binding and immunotherapy of cancer. The second edition comes in 3 volumes. Volume 1 is focused on nanoparticle characterization, sterility and sterilization, pyrogen contamination and depyrigenation. It also contains overview of regulatory guidelines, protocols for in vitro and in vivo immunotoxicity studies, and correlation between in vitro and in vivo immunoassays. Volume 2 is focused on hematocompatibility of nanomaterials. It provides comprehensive review and protocols for investigating nanoparticle interaction with erythrocytes, platelets, endothelial cells, plasma coagulation factors and plasma proteins forming so called 'corona' around nanoparticles. Volume 3 is dedicated to nanoparticle interaction with and effects on the immune cell function. It also contains examples of nanoparticle use for delivery of antiviral and anti-inflammatory drugs.

Handbook of Immunological Properties of Engineered Nanomaterials

Author : Marina Dobrovolskaia
Publisher : World Scientific
ISBN 13 : 9814390259
Total Pages : 721 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Handbook of Immunological Properties of Engineered Nanomaterials by : Marina Dobrovolskaia

Download or read book Handbook of Immunological Properties of Engineered Nanomaterials written by Marina Dobrovolskaia and published by World Scientific. This book was released on 2013 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.

Handbook of Immunological Properties of Engineered Nanomaterials (Second Edition) (in 3 Volumes)

Author : Marina A Dobrovolskaia
Publisher :
ISBN 13 : 9789814699167
Total Pages : pages
Book Rating : 4.6/5 (991 download)

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Book Synopsis Handbook of Immunological Properties of Engineered Nanomaterials (Second Edition) (in 3 Volumes) by : Marina A Dobrovolskaia

Download or read book Handbook of Immunological Properties of Engineered Nanomaterials (Second Edition) (in 3 Volumes) written by Marina A Dobrovolskaia and published by . This book was released on 2016-01-29 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book provides comprehensive overview of the field of immunology related to engineered nanomaterials used for biomedical applications. It contains literature review, case studies and protocols. The book can serve as a source of information about nanoimmunotoxicology for both junior scientists and experts in the field. The authors have more than 10 years of experience with preclinical characterization of engineered nanomaterials used for medical applications, and they share their experience with the readers. In addition, the international team of experts in the field provides the opinion and share the expertise on individual topics related to nanoparticle physicochemical characterization, hematocompatibility, and effects on the immune cell function . The second edition contains updated chapters from the first edition plus new chapters covering areas of tumor immunology, nanoparticle interaction with lymphatic system, mathematical modeling of protein corona, utilization of nanoparticles for the delivery of antiviral drugs, extensive analysis of nanoparticle anti-inflammatory and immunosuppressive properties, novel ways of protecting therapeutic nanoparticles from the immune recognition, as well as case studies regarding nanoparticle sterilization, complement activation, protein binding and immunotherapy of cancer. The second edition comes in 3 volumes. Volume 1 is focused on nanoparticle characterization, sterility and sterilization, pyrogen contamination and depyrigenation. It also contains overview of regulatory guidelines, protocols for in vitro and in vivo immunotoxicity studies, and correlation between in vitro and in vivo immunoassays. Volume 2 is focused on hematocompatibility of nanomaterials. It provides comprehensive review and protocols for investigating nanoparticle interaction with erythrocytes, platelets, endothelial cells, plasma coagulation factors and plasma proteins forming so called 'corona' around nanoparticles. Volume 3 is dedicated to nanoparticle interaction with and effects on the immune cell function. It also contains examples of nanoparticle use for delivery of antiviral and anti-inflammatory drugs.

Handbook of Immunological Properties of Engineered Nanomaterials

Author : Dobrovolskaia Marina A
Publisher :
ISBN 13 : 9789814699174
Total Pages : 1184 pages
Book Rating : 4.6/5 (991 download)

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Book Synopsis Handbook of Immunological Properties of Engineered Nanomaterials by : Dobrovolskaia Marina A

Download or read book Handbook of Immunological Properties of Engineered Nanomaterials written by Dobrovolskaia Marina A and published by . This book was released on 2016 with total page 1184 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This unique book provides comprehensive overview of the field of immunology related to engineered nanomaterials used for biomedical applications. It contains literature review, case studies and protocols. The book can serve as a source of information about nanoimmunotoxicology for both junior scientists and experts in the field. The authors have more than 10 years of experience with preclinical characterization of engineered nanomaterials used for medical applications, and they share their experience with the readers. In addition, the international team of experts in the field provides the opinion and share the expertise on individual topics related to nanoparticle physicochemical characterization, hematocompatibility, and effects on the immune cell function . The second edition contains updated chapters from the first edition plus new chapters covering areas of tumor immunology, nanoparticle interaction with lymphatic system, mathematical modeling of protein corona, utilization of nanoparticles for the delivery of antiviral drugs, extensive analysis of nanoparticle anti-inflammatory and immunosuppressive properties, novel ways of protecting therapeutic nanoparticles from the immune recognition, as well as case studies regarding nanoparticle sterilization, complement activation, protein binding and immunotherapy of cancer. The second edition comes in 3 volumes. Volume 1 is focused on nanoparticle characterization, sterility and sterilization, pyrogen contamination and depyrigenation. It also contains overview of regulatory guidelines, protocols for in vitro and in vivo immunotoxicity studies, and correlation between in vitro and in vivo immunoassays. Volume 2 is focused on hematocompatibility of nanomaterials. It provides comprehensive review and protocols for investigating nanoparticle interaction with erythrocytes, platelets, endothelial cells, plasma coagulation factors and plasma proteins forming so called "corona" around nanoparticles. Volume 3 is dedicated to nanoparticle interaction with and effects on the immune cell function. It also contains examples of nanoparticle use for delivery of antiviral and anti-inflammatory drugs."--Provided by publisher

Interaction of Nanomaterials with the Immune System

Author : James C. Bonner
Publisher : Springer Nature
ISBN 13 : 3030339629
Total Pages : 229 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Interaction of Nanomaterials with the Immune System by : James C. Bonner

Download or read book Interaction of Nanomaterials with the Immune System written by James C. Bonner and published by Springer Nature. This book was released on 2020-01-30 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs). Many ENMs used in both the consumer and biomedical fields have been reported to elicit adverse immune responses ranging from innate immune responses such as complement activation to changes in adaptive immunity that influence pathogen responses and promote disease states such as asthma. Interaction of Nanomaterials with the Immune System covers the most up to date information on our understanding of immune responses to ENMs across a wide range of topics including innate immunity, allergic immune responses, adaptive provides the reader with (1) up to date understanding of immune responses to ENMs; (2) current testing methods; and (3) appropriate models including alternative testing strategies for evaluating immunotoxicity of ENMs.

Immune Aspects of Biopharmaceuticals and Nanomedicines

Author : Raj Bawa
Publisher : CRC Press
ISBN 13 : 1351399780
Total Pages : 44 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Immune Aspects of Biopharmaceuticals and Nanomedicines by : Raj Bawa

Download or read book Immune Aspects of Biopharmaceuticals and Nanomedicines written by Raj Bawa and published by CRC Press. This book was released on 2019-01-10 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enormous advances in the immunologic aspects of biotherapeutics and nanomedicines in the past two decades has necessitated an authoritative and comprehensive reference source that can be relied upon by immunologists, biomedical researchers, clinicians, pharmaceutical companies, regulators, venture capitalists, and policy makers alike. This text provides a thorough understanding of immunology, therapeutic potential, clinical applications, adverse reactions, and approaches to overcoming immunotoxicity of biotherapeutics and nanomedicines. It also tackles critical, yet often overlooked topics such as immune aspects of nano-bio interactions, current FDA regulatory guidances, complement activation-related pseudoallergy (CARPA), advances in nanovaccines, and immunogenicity testing of protein therapeutics.

Polymer Nanoparticles for Nanomedicines

Author : Christine Vauthier
Publisher : Springer
ISBN 13 : 3319414216
Total Pages : 641 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Polymer Nanoparticles for Nanomedicines by : Christine Vauthier

Download or read book Polymer Nanoparticles for Nanomedicines written by Christine Vauthier and published by Springer. This book was released on 2017-01-07 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.

The Immune Response to Implanted Materials and Devices

Author : Bruna Corradetti
Publisher : Springer
ISBN 13 : 3319454331
Total Pages : 241 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis The Immune Response to Implanted Materials and Devices by : Bruna Corradetti

Download or read book The Immune Response to Implanted Materials and Devices written by Bruna Corradetti and published by Springer. This book was released on 2016-11-30 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.

Interaction of Nanomaterials With the Immune System: Role in Nanosafety and Nanomedicine

Author : Paola Italiani
Publisher : Frontiers Media SA
ISBN 13 : 2889453871
Total Pages : 177 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Interaction of Nanomaterials With the Immune System: Role in Nanosafety and Nanomedicine by : Paola Italiani

Download or read book Interaction of Nanomaterials With the Immune System: Role in Nanosafety and Nanomedicine written by Paola Italiani and published by Frontiers Media SA. This book was released on 2018-04-10 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune system has the double role of maintaining tissue integrity and homeostasis and of protecting the organism from possible dangers, from invading pathogens to environmentally-borne dangerous chemicals. New chemicals recognisable by the immune system are engineered nanomaterials/ nanoparticles, new agents in our environment that are becoming common due to their presence in many products, from constructions and building material (e.g., solar cells, pigments and paints, tilesand masonry materials) to daily products (e.g., food packaging, cosmetics, and cigarettes). Human beings can be accidentally exposed to engineered nanomaterials when these are released from products containing them or during production in workplaces. Furthermore, intentional exposure occurs in medicine, as engineered nanoparticles are used as tools for improving delivery of drugs and vaccines, vaccine adjuvants and contrast agents in therapeutic, preventive and diagnostic strategies. Nanoparticles that come in contact with the immune system after unintentional exposure need to be eliminated from the organism as they represent a potential threat. In this case, however, due to their peculiar characteristics of size, shape, surface charge and persistence, nanoparticles may elicit undesirable reactions and have detrimental effects on the immune system, such as cytotoxicity, inflammation, anaphylaxis, immunosuppression. Conversely, nanomedicines need to escape immune recognition/elimination and must persist in the organism long enough for reaching their target and exerting their beneficial effects. Immune cells and molecules at the body surface (airway and digestive mucosae, skin) are the first that come in contact with nanomaterials upon accidental exposure, while immune effectors in blood are those that more easily come in contact with nanomedical products. Thus, evaluating the interaction of the immune system with nanoparticles/nanomaterials is a topic of key importance both in nanotoxicology and in nanomedicine. Immuno-nanosafety studies consider both accidental exposure to nanoparticles, which may occur by skin contact, ingestion or inhalation (at doses and with a frequency that are not known), and medical exposure, which takes place with a defined administration schedule (route, dose, frequency). Many studies focus on the interaction between the immune system and nanoparticles that, for medical purposes, have been specifically modified to stimulate immunity or to avoid immune recognition, as in the case of vaccine carriers/adjuvants or drug delivery systems, respectively. The aims of this Research Topic is to provide an overview of recent strategies: 1.for assessing the immunosafety of engineered nanomaterials/nanoparticles, in particular in terms of activation of inflammatory responses, such as complement activation and allergic reactions, based on the nanomaterial intrinsic characteristics and on the possible carry-over of bioactive contaminants such as LPS. Production of new nanoparticles taking into account their effects on immune responses, in order to avoid undesirable effects on one hand, and to design particles with desirable effects for medical applications on the other hand; 2.for designing more effective nanomedicines by either avoiding or exploiting their interaction with the immune systems, with particular focus on cancer diagnosis and therapy, and vaccination. This collection of articles gives a comprehensive view of the state-of-the-art of the interaction of nanoparticles with the immune system from the two perspectives of safety and medical use, and aims at providing immunologists with the relevant knowledge for designing improved strategies for immunologically safe nanomaterial applications.

Textile-Based Advanced Materials

Author : Thomas Bechtold
Publisher : MDPI
ISBN 13 : 3036504206
Total Pages : 248 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Textile-Based Advanced Materials by : Thomas Bechtold

Download or read book Textile-Based Advanced Materials written by Thomas Bechtold and published by MDPI. This book was released on 2021-03-17 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developments in the science and technology of textiles are not only limited to apparel and fashion. Certainly, there are research efforts aimed at improving the construction and processing of textiles for clothing—such as studies on cleaner production to reduce environmental impact, increasing the utilization of fibers and process chemicals from renewable resources, and on the recycling of materials from post-consumer waste apparel back into the manufacturing of new clothing articles. In addition, technological concepts developed for the creation of clothing over the centuries are now being investigated for use in a diverse array of fields—such as in the manufacture of engineering composites, personal protective equipment, and medicine. Further, developments in other fields—such as electronics, nanotechnology, and information and communication technologies—are being investigated for their incorporation into apparel and clothing to create “smart textiles”. The aim of this Special Issue is to put together a collection of scientific reports on such efforts to highlight the range of scientific and technological issues that are being targeted and the ingenuity of the methodologies employed to find answers. It is hoped that readers of this issue will come away with an appreciation of the research being conducted in this area, and perhaps gain inspiration for their own scientific endeavors.

Immune Rebalancing

Author : Diana Boraschi
Publisher : Academic Press
ISBN 13 : 0128033363
Total Pages : 298 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Immune Rebalancing by : Diana Boraschi

Download or read book Immune Rebalancing written by Diana Boraschi and published by Academic Press. This book was released on 2016-01-25 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Rebalancing: The Future of Immunosuppression summarizes the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression by considering molecular pathways, personalized medicine, microbiome and nanomedicine. Modulation of immune responses for therapeutic purposes is a particularly relevant area, given the central role of anomalous immunity in diseases. These diseases vary from the most typically immune-related syndromes (autoimmune diseases, allergy and asthma, immunodeficiencies) to those in which altered immunity and inflammation define the pathological outcomes (chronic infections, tumours, chronic inflammatory and degenerative diseases, metabolic disorders, etc. Visits immunosuppression from a modern point of view of signalling mechanisms at the light of the current knowledge of signalling mechanisms and regulatory networks allows the reader to formulate new ideas and concepts on how to use immunosuppression the therapeutic purposes Encourages researchers to engage into exploring the field of pharmacological modulation of immune responses in depth, and with the new knowledge and tools available, designs more effective therapeutic strategies to autoimmune and inflammatory diseases, cancer, degenerative diseases and infections Examines the link between molecular pathways associated to immune-suppression and the new immunopharmacology approaches Provides information on the new strategies for drug development in this field Considers the role of microbes in the development of the mammalian immune system and immune responses, which will widen the reader’s strategy for addressing therapeutic immune modulations

Handbook of Safety Assessment of Nanomaterials

Author : Bengt Fadeel
Publisher : CRC Press
ISBN 13 : 981446337X
Total Pages : 562 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Handbook of Safety Assessment of Nanomaterials by : Bengt Fadeel

Download or read book Handbook of Safety Assessment of Nanomaterials written by Bengt Fadeel and published by CRC Press. This book was released on 2014-12-10 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly evolving field of nanomedicine refers to the clinical application of nanotechnologies. However, as with all new technologies, there are ethical, safety, and regulatory issues. This handbook, written by leading international experts, provides a meticulous overview of the state of the art of safety assessment of nanomaterials (nanotoxicology) in the context of their application in nanomedicine. The volume includes a historical perspective on the development of nanomedicine and its regulation, and a personal view of the future of (nano)medicine by Patrick Hunziker, president of the European Society of Nanomedicine. Ethical considerations in relation to nanomedicine are discussed. There are a series of chapters on organ-specific toxicities of nanomaterials, including pulmonary and cardiovascular toxicity, neurotoxicity, dermatotoxicity, and reproductive toxicity, as well as a discussion on immunotoxicity and genotoxicity. The importance of a thorough characterization of physicochemical properties of nanomaterials is emphasized. The handbook also contains a critical discussion on the applicability of in vitro versus in vivo methods and models for nanosafety assessment, along with an introduction to mathematical modeling approaches with a view to a predictive toxicology of nanomaterials. The overall aim is to provide a comprehensive, science-based framework for safety assessment of current and future nanomedicines.

World Scientific Encyclopedia Of Nanomedicine And Bioengineering I, The: Nanotechnology For Translational Medicine: Tissue Engineering, Biological Sensing, Medical Imaging, And Therapeutics (A 4-volume Set)

Download World Scientific Encyclopedia Of Nanomedicine And Bioengineering I, The: Nanotechnology For Translational Medicine: Tissue Engineering, Biological Sensing, Medical Imaging, And Therapeutics (A 4-volume Set) PDF Online Free

Author :
Publisher : World Scientific
ISBN 13 : 9814667676
Total Pages : 1156 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis World Scientific Encyclopedia Of Nanomedicine And Bioengineering I, The: Nanotechnology For Translational Medicine: Tissue Engineering, Biological Sensing, Medical Imaging, And Therapeutics (A 4-volume Set) by :

Download or read book World Scientific Encyclopedia Of Nanomedicine And Bioengineering I, The: Nanotechnology For Translational Medicine: Tissue Engineering, Biological Sensing, Medical Imaging, And Therapeutics (A 4-volume Set) written by and published by World Scientific. This book was released on 2016-08-30 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-part multivolume set provides a comprehensive overview of current achievements in biomedical applications of nanotechnology, including stem cell based regenerative medicine, medical imaging, cell targeting, drug delivery, and photothermal/photodynamic cancer therapy. New approaches in early cancer diagnosis and treatment are introduced with extensive experimental results. In particular, some novel materials have been synthesized with new properties that are most effective in cancer therapy. Some of the key issues are also addressed with these recent discoveries such as bio safety and bio degradability, that are essential in the success of nano medicine. An important aspect of this book set is the introduction of nanotechnology to the medical communities that are searching for new treatments of cancer. It may also break the barriers between the physical and medical sciences so that more MDs will be able to appreciate the new discoveries and establishments in medical diagnosis and therapy that will allow the effective handling of major clinical issues. This major reference publication will be important as the field of nanomedicine has been rapidly developing with a great deal of new information. It is anticipated that the research will soon advance into the pre-clinical stage. Therefore, this reference set can serve as valuable background information for future clinical studies.

Multiscale Technologies For Cryomedicine: Implementation From Nano To Macroscale

Author : Bischof John C
Publisher : World Scientific
ISBN 13 : 9814733202
Total Pages : 388 pages
Book Rating : 4.8/5 (147 download)

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Book Synopsis Multiscale Technologies For Cryomedicine: Implementation From Nano To Macroscale by : Bischof John C

Download or read book Multiscale Technologies For Cryomedicine: Implementation From Nano To Macroscale written by Bischof John C and published by World Scientific. This book was released on 2016-06-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of micro / nanotechnology in cell and tissue engineering, and especially for cell and tissue preservation, is at the peak of its activity now, with scientific output expected to continue growing in the coming years.Micro and nanotechnologies have induced paradigm shifts in many scientific fields, and as featured in this edited volume, they are having important impact in the field of cryomedicine. The book gives an overview of the recent progress in implementing multiscale (micro and nanoscale) technologies to improve the outcome of various cryomedical applications including cryosurgery, cryopreservation, lyopreservation and to understand the fundamental engineering and science underpinning the applications.This is the first book that will provide both an introductory and in-depth account of applying the multiscale technologies in cryomedicine.

Hybrid Nanomaterials for Drug Delivery

Author : Prashant Kesharwani
Publisher : Woodhead Publishing
ISBN 13 : 0323903568
Total Pages : 408 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Hybrid Nanomaterials for Drug Delivery by : Prashant Kesharwani

Download or read book Hybrid Nanomaterials for Drug Delivery written by Prashant Kesharwani and published by Woodhead Publishing. This book was released on 2022-02-02 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hybrid Nanomaterials for Drug Delivery covers a broad range of hybrid nanomaterials and nanocomposites used in drug delivery systems. The book reviews a variety of hybrid nanomaterials and structures, including polymer-lipid, chitosan-based, protein-inorganic, quantum dot hybrids, and more. The strengths, limitations and regulatory aspects of hybrid drug delivery systems are also discussed, allowing readers to make informed decisions when choosing to utilize hybrid nanomaterials. Users will find this to be an exciting and comprehensive look into this emerging area. It will be of particular interest to academics and researchers working in materials science, engineering, biomedical engineering, nanotechnology and pharmaceutical science. Multi nanocarrier-based hybrid systems are an emerging concept in the field of drug delivery that allow researchers to avoid some of the challenges faced when administering drugs, such as low bioavailability, development of drug resistance, toxicities, premature drug release, and therapeutic efficacy. Describes the properties, synthesis and application of hybrid nanomaterials for use in drug delivery systems Reviews a variety of hybrid nanomaterials and structures, including dendrimer, silica-based, polymer-metal, nanogel systems, and more Discusses the strengths, limitations and regulatory aspects of hybrid drug delivery systems

Nanotoxicology in Humans and the Environment

Author : Jamie R. Lead
Publisher : Springer Nature
ISBN 13 : 3030798089
Total Pages : 263 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Nanotoxicology in Humans and the Environment by : Jamie R. Lead

Download or read book Nanotoxicology in Humans and the Environment written by Jamie R. Lead and published by Springer Nature. This book was released on 2021-12-13 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book covers the area of ‘Nanotoxicology’ but primarily from the point of view of nanotoxicology at the interface with other disciplines including human toxicology; environmental toxicology; characterization, dose and transformations; regulation; public and elite group perceptions; and interactions with innovation.Nanotoxicology in Humans and the Environment is written for researchers in nanotoxicology in academia, industry, government, and research students. Given the rapid development, the maturing of the discipline and its importance in current regulation and industry development (eg REACH, TSCA), the book is very timely.

Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 2

Author : Wanda M. Haschek-Hock
Publisher : Academic Press
ISBN 13 : 0323910521
Total Pages : 694 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 2 by : Wanda M. Haschek-Hock

Download or read book Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 2 written by Wanda M. Haschek-Hock and published by Academic Press. This book was released on 2023-02-18 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 2: Toxicologic Pathology in Safety Assessment is an essential part of the most authoritative reference on toxicologic pathology principles and techniques for assessing product safety and human risk. Volume 2 describes the integration of product-induced structural and functional changes in tissues and the interpretation of their biological implications. Completely revised with many new chapters, Volume 2 of the Fourth Edition covers product safety assessment from many angles including current and emerging issues in toxicologic pathology for many product classes. Volume 2 of the Handbook of Toxicologic Pathology is a key resource for pathologists, toxicologists, research scientists, and regulators who use toxicologic pathology methods to study and make decisions on product safety. Previous chapters on such topics as drug discovery and development, toxicity and carcinogenicity testing, report preparation, and risk assessment and communication have undergone extensive revision that includes in-depth discussion of new developments in the field New chapters consider fundamental attributes for additional product classes including protein therapeutics, nucleic acid pharmaceutical agents, gene therapy and gene editing, stem cell and other cell therapies, vaccines, agricultural and bulk chemicals, and assigning adversity Chapters dealing with product-specific practices address pathology and regulatory issues Chapters offer high-quality and up-to-date content in a trusted work written by the collaborative efforts of many leading international subject matter experts Hundreds of full-color images and diagrams are featured in both the print and electronic versions of this book to illustrate classic examples and highlight difficult concepts