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Principles Of Computational Modelling In Neuroscience
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Book Synopsis Principles of Computational Modelling in Neuroscience by : David Sterratt
Download or read book Principles of Computational Modelling in Neuroscience written by David Sterratt and published by Cambridge University Press. This book was released on 2023-10-05 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to use computational modelling techniques to understand the nervous system at all levels, from ion channels to networks.
Book Synopsis Principles of Computational Modelling in Neuroscience by : David Sterratt
Download or read book Principles of Computational Modelling in Neuroscience written by David Sterratt and published by Cambridge University Press. This book was released on 2023-10-05 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a step-by-step and practical account of how to model neurons and neural circuitry, this textbook is designed for advanced undergraduate and postgraduate students of computational neuroscience as well as for researchers in neuroscience and related sciences wishing to apply computational approaches to interpret data and make predictions.
Book Synopsis Principles of Computational Modelling in Neuroscience by : David Sterratt
Download or read book Principles of Computational Modelling in Neuroscience written by David Sterratt and published by Cambridge University Press. This book was released on 2011-06-30 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nervous system is made up of a large number of interacting elements. To understand how such a complex system functions requires the construction and analysis of computational models at many different levels. This book provides a step-by-step account of how to model the neuron and neural circuitry to understand the nervous system at all levels, from ion channels to networks. Starting with a simple model of the neuron as an electrical circuit, gradually more details are added to include the effects of neuronal morphology, synapses, ion channels and intracellular signalling. The principle of abstraction is explained through chapters on simplifying models, and how simplified models can be used in networks. This theme is continued in a final chapter on modelling the development of the nervous system. Requiring an elementary background in neuroscience and some high school mathematics, this textbook is an ideal basis for a course on computational neuroscience.
Book Synopsis Principles of Computational Modelling in Neuroscience by : David Sterratt
Download or read book Principles of Computational Modelling in Neuroscience written by David Sterratt and published by Cambridge University Press. This book was released on 2011-06-30 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nervous system is made up of a large number of interacting elements. To understand how such a complex system functions requires the construction and analysis of computational models at many different levels. This book provides a step-by-step account of how to model the neuron and neural circuitry to understand the nervous system at all levels, from ion channels to networks. Starting with a simple model of the neuron as an electrical circuit, gradually more details are added to include the effects of neuronal morphology, synapses, ion channels and intracellular signaling. The principle of abstraction is explained through chapters on simplifying models, and how simplified models can be used in networks. This theme is continued in a final chapter on modeling the development of the nervous system. Requiring an elementary background in neuroscience and some high school mathematics, this textbook is an ideal basis for a course on computational neuroscience.
Book Synopsis Principles of Computational Modelling in Neuroscience by :
Download or read book Principles of Computational Modelling in Neuroscience written by and published by . This book was released on 2011 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The nervous system is made up of a large number of interacting elements. To understand how such a complex system functions requires the construction and analysis of computational models at many different levels. This book provides a step-by-step account of how to model the neuron and neural circuitry to understand the nervous system at all levels, from ion channels to networks. Starting with a simple model of the neuron as an electrical circuit, gradually more details are added to include the effects of neuronal morphology, synapses, ion channels and intracellular signalling. The principle of abstraction is explained through chapters on simplifying models, and how simplified models can be used in networks. This theme is continued in a final chapter on modelling the development of the nervous system. Requiring an elementary background in neuroscience and some high school mathematics, this textbook is an ideal basis for a course on computational neuroscience"--
Book Synopsis Computational Modeling Methods for Neuroscientists by : Erik De Schutter
Download or read book Computational Modeling Methods for Neuroscientists written by Erik De Schutter and published by National Geographic Books. This book was released on 2009-09-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to computational modeling methods in neuroscience, covering a range of modeling scales from molecular reactions to large neural networks. This book offers an introduction to current methods in computational modeling in neuroscience. The book describes realistic modeling methods at levels of complexity ranging from molecular interactions to large neural networks. A “how to” book rather than an analytical account, it focuses on the presentation of methodological approaches, including the selection of the appropriate method and its potential pitfalls. It is intended for experimental neuroscientists and graduate students who have little formal training in mathematical methods, but it will also be useful for scientists with theoretical backgrounds who want to start using data-driven modeling methods. The mathematics needed are kept to an introductory level; the first chapter explains the mathematical methods the reader needs to master to understand the rest of the book. The chapters are written by scientists who have successfully integrated data-driven modeling with experimental work, so all of the material is accessible to experimentalists. The chapters offer comprehensive coverage with little overlap and extensive cross-references, moving from basic building blocks to more complex applications. Contributors Pablo Achard, Haroon Anwar, Upinder S. Bhalla, Michiel Berends, Nicolas Brunel, Ronald L. Calabrese, Brenda Claiborne, Hugo Cornelis, Erik De Schutter, Alain Destexhe, Bard Ermentrout, Kristen Harris, Sean Hill, John R. Huguenard, William R. Holmes, Gwen Jacobs, Gwendal LeMasson, Henry Markram, Reinoud Maex, Astrid A. Prinz, Imad Riachi, John Rinzel, Arnd Roth, Felix Schürmann, Werner Van Geit, Mark C. W. van Rossum, Stefan Wils
Book Synopsis Cognitive and Computational Neuroscience by : Seyyed Abed Hosseini
Download or read book Cognitive and Computational Neuroscience written by Seyyed Abed Hosseini and published by BoD – Books on Demand. This book was released on 2018-05-30 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book "Cognitive and Computational Neuroscience - Principles, Algorithms and Applications" will answer the following question and statements: System-level neural modeling: what and why? We know a lot about the brain! Need to integrate data: molecular/cellular/system levels. Complexity: need to abstract away higher-order principles. Models are tools to develop explicit theories, constrained by multiple levels (neural and behavioral). Key: models (should) make novel testable predictions on both neural and behavioral levels. Models are useful tools for guiding experiments. The hope is that the information provided in this book will trigger new researches that will help to connect basic neuroscience to clinical medicine.
Book Synopsis Computational Models of Brain and Behavior by : Ahmed A. Moustafa
Download or read book Computational Models of Brain and Behavior written by Ahmed A. Moustafa and published by John Wiley & Sons. This book was released on 2017-11-13 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimer's disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Master's and PhD-level students—as well as researchers involved in computational neuroscience modeling research.
Book Synopsis Biophysics of Computation by : Christof Koch
Download or read book Biophysics of Computation written by Christof Koch and published by Oxford University Press. This book was released on 2004-10-28 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can be encoded in the voltage across the membrane, in the intracellular calcium concentration, or in the timing of individual spikes.Key topics covered include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; chemical and electrical synapses and how to treat them from a computational point of view; nonlinear interactions of synaptic input in passive and active dendritic trees; the Hodgkin-Huxley model of action potential generation and propagation; phase space analysis; linking stochastic ionic channels to membrane-dependent currents; calcium and potassium currents and their role in information processing; the role of diffusion, buffering and binding of calcium, and other messenger systems in information processing and storage; short- and long-term models of synaptic plasticity; simplified models of single cells; stochastic aspects of neuronal firing; the nature of the neuronal code; and unconventional models of sub-cellular computation.Biophysics of Computation: Information Processing in Single Neurons serves as an ideal text for advanced undergraduate and graduate courses in cellular biophysics, computational neuroscience, and neural networks, and will appeal to students and professionals in neuroscience, electrical and computer engineering, and physics.
Book Synopsis The Computational Brain by : Patricia Smith Churchland
Download or read book The Computational Brain written by Patricia Smith Churchland and published by MIT Press. This book was released on 1992 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Computational Brain addresses a broad audience: neuroscientists, computer scientists, cognitive scientists, and philosophers. It is written for both the expert and novice. A basic overview of neuroscience and computational theory is provided, followed by a study of some of the most recent and sophisticated modeling work in the context of relevant neurobiological research. Technical terms are clearly explained in the text, and definitions are provided in an extensive glossary. The appendix contains a précis of neurobiological techniques."--Jacket.
Book Synopsis An Introductory Course in Computational Neuroscience by : Paul Miller
Download or read book An Introductory Course in Computational Neuroscience written by Paul Miller and published by MIT Press. This book was released on 2018-10-02 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: A textbook for students with limited background in mathematics and computer coding, emphasizing computer tutorials that guide readers in producing models of neural behavior. This introductory text teaches students to understand, simulate, and analyze the complex behaviors of individual neurons and brain circuits. It is built around computer tutorials that guide students in producing models of neural behavior, with the associated Matlab code freely available online. From these models students learn how individual neurons function and how, when connected, neurons cooperate in a circuit. The book demonstrates through simulated models how oscillations, multistability, post-stimulus rebounds, and chaos can arise within either single neurons or circuits, and it explores their roles in the brain. The book first presents essential background in neuroscience, physics, mathematics, and Matlab, with explanations illustrated by many example problems. Subsequent chapters cover the neuron and spike production; single spike trains and the underlying cognitive processes; conductance-based models; the simulation of synaptic connections; firing-rate models of large-scale circuit operation; dynamical systems and their components; synaptic plasticity; and techniques for analysis of neuron population datasets, including principal components analysis, hidden Markov modeling, and Bayesian decoding. Accessible to undergraduates in life sciences with limited background in mathematics and computer coding, the book can be used in a “flipped” or “inverted” teaching approach, with class time devoted to hands-on work on the computer tutorials. It can also be a resource for graduate students in the life sciences who wish to gain computing skills and a deeper knowledge of neural function and neural circuits.
Book Synopsis Principles of Computational Modelling in Neuroscience by : David Sterratt
Download or read book Principles of Computational Modelling in Neuroscience written by David Sterratt and published by . This book was released on 2014-05-14 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to use techniques of computational modelling to understand the nervous system at all levels from ion channels to networks.
Book Synopsis Fundamentals of Computational Neuroscience by : Thomas Trappenberg
Download or read book Fundamentals of Computational Neuroscience written by Thomas Trappenberg and published by Oxford University Press. This book was released on 2010 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of Fundamentals of Computational Neuroscience build on the success and strengths of the first edition. Completely redesigned and revised, it introduces the theoretical foundations of neuroscience with a focus on the nature of information processing in the brain.
Book Synopsis The Computational Neurobiology of Reaching and Pointing by : Reza Shadmehr
Download or read book The Computational Neurobiology of Reaching and Pointing written by Reza Shadmehr and published by MIT Press. This book was released on 2004-10-28 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the computational biology of reaching and pointing, with an emphasis on motor learning. Neuroscience involves the study of the nervous system, and its topics range from genetics to inferential reasoning. At its heart, however, lies a search for understanding how the environment affects the nervous system and how the nervous system, in turn, empowers us to interact with and alter our environment. This empowerment requires motor learning. The Computational Neurobiology of Reaching and Pointing addresses the neural mechanisms of one important form of motor learning. The authors integrate material from the computational, behavioral, and neural sciences of motor control that is not available in any other single source. The result is a unified, comprehensive model of reaching and pointing. The book is intended to be used as a text by graduate students in both neuroscience and bioengineering and as a reference source by experts in neuroscience, robotics, and other disciplines. The book begins with an overview of the evolution, anatomy, and physiology of the motor system, including the mechanisms for generating force and maintaining limb stability. The sections that follow, "Computing Locations and Displacements", "Skills, Adaptations, and Trajectories", and "Predictions, Decisions, and Flexibility", present a theory of sensorially guided reaching and pointing that evolves organically based on computational principles rather than a traditional structure-by-structure approach. The book also includes five appendixes that provide brief refreshers on fundamentals of biology, mathematics, physics, and neurophysiology, as well as a glossary of relevant terms. The authors have also made supplemental materials available on the Internet. These web documents provide source code for simulations, step-by-step derivations of certain mathematical formulations, and expanded explanations of some concepts.
Book Synopsis Dynamical Systems in Neuroscience by : Eugene M. Izhikevich
Download or read book Dynamical Systems in Neuroscience written by Eugene M. Izhikevich and published by MIT Press. This book was released on 2010-01-22 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the relationship of electrophysiology, nonlinear dynamics, and the computational properties of neurons, with each concept presented in terms of both neuroscience and mathematics and illustrated using geometrical intuition. In order to model neuronal behavior or to interpret the results of modeling studies, neuroscientists must call upon methods of nonlinear dynamics. This book offers an introduction to nonlinear dynamical systems theory for researchers and graduate students in neuroscience. It also provides an overview of neuroscience for mathematicians who want to learn the basic facts of electrophysiology. Dynamical Systems in Neuroscience presents a systematic study of the relationship of electrophysiology, nonlinear dynamics, and computational properties of neurons. It emphasizes that information processing in the brain depends not only on the electrophysiological properties of neurons but also on their dynamical properties. The book introduces dynamical systems, starting with one- and two-dimensional Hodgkin-Huxley-type models and continuing to a description of bursting systems. Each chapter proceeds from the simple to the complex, and provides sample problems at the end. The book explains all necessary mathematical concepts using geometrical intuition; it includes many figures and few equations, making it especially suitable for non-mathematicians. Each concept is presented in terms of both neuroscience and mathematics, providing a link between the two disciplines. Nonlinear dynamical systems theory is at the core of computational neuroscience research, but it is not a standard part of the graduate neuroscience curriculum—or taught by math or physics department in a way that is suitable for students of biology. This book offers neuroscience students and researchers a comprehensive account of concepts and methods increasingly used in computational neuroscience. An additional chapter on synchronization, with more advanced material, can be found at the author's website, www.izhikevich.com.
Book Synopsis Computational Explorations in Cognitive Neuroscience by : Randall C. O'Reilly
Download or read book Computational Explorations in Cognitive Neuroscience written by Randall C. O'Reilly and published by MIT Press. This book was released on 2000-08-28 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text, based on a course taught by Randall O'Reilly and Yuko Munakata over the past several years, provides an in-depth introduction to the main ideas in the computational cognitive neuroscience. The goal of computational cognitive neuroscience is to understand how the brain embodies the mind by using biologically based computational models comprising networks of neuronlike units. This text, based on a course taught by Randall O'Reilly and Yuko Munakata over the past several years, provides an in-depth introduction to the main ideas in the field. The neural units in the simulations use equations based directly on the ion channels that govern the behavior of real neurons, and the neural networks incorporate anatomical and physiological properties of the neocortex. Thus the text provides the student with knowledge of the basic biology of the brain as well as the computational skills needed to simulate large-scale cognitive phenomena. The text consists of two parts. The first part covers basic neural computation mechanisms: individual neurons, neural networks, and learning mechanisms. The second part covers large-scale brain area organization and cognitive phenomena: perception and attention, memory, language, and higher-level cognition. The second part is relatively self-contained and can be used separately for mechanistically oriented cognitive neuroscience courses. Integrated throughout the text are more than forty different simulation models, many of them full-scale research-grade models, with friendly interfaces and accompanying exercises. The simulation software (PDP++, available for all major platforms) and simulations can be downloaded free of charge from the Web. Exercise solutions are available, and the text includes full information on the software.
Book Synopsis The Computational Brain, 25th Anniversary Edition by : Patricia S. Churchland
Download or read book The Computational Brain, 25th Anniversary Edition written by Patricia S. Churchland and published by MIT Press. This book was released on 2016-11-04 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: An anniversary edition of the classic work that influenced a generation of neuroscientists and cognitive neuroscientists. Before The Computational Brain was published in 1992, conceptual frameworks for brain function were based on the behavior of single neurons, applied globally. In The Computational Brain, Patricia Churchland and Terrence Sejnowski developed a different conceptual framework, based on large populations of neurons. They did this by showing that patterns of activities among the units in trained artificial neural network models had properties that resembled those recorded from populations of neurons recorded one at a time. It is one of the first books to bring together computational concepts and behavioral data within a neurobiological framework. Aimed at a broad audience of neuroscientists, computer scientists, cognitive scientists, and philosophers, The Computational Brain is written for both expert and novice. This anniversary edition offers a new preface by the authors that puts the book in the context of current research. This approach influenced a generation of researchers. Even today, when neuroscientists can routinely record from hundreds of neurons using optics rather than electricity, and the 2013 White House BRAIN initiative heralded a new era in innovative neurotechnologies, the main message of The Computational Brain is still relevant.
