Principles and Practices of DNA Analysis

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Publisher :
ISBN 13 : 9781071602744
Total Pages : 344 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Principles and Practices of DNA Analysis by : Hirak Ranjan Dash

Download or read book Principles and Practices of DNA Analysis written by Hirak Ranjan Dash and published by . This book was released on 2020 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Forensic DNA Analysis

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Publisher : CRC Press
ISBN 13 : 1420063308
Total Pages : 178 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Forensic DNA Analysis by : J. Thomas McClintock

Download or read book Forensic DNA Analysis written by J. Thomas McClintock and published by CRC Press. This book was released on 2008-02-19 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its short but active history, the use of DNA typing has revolutionized criminal investigations. It is almost inconceivable to bring a case to trial without positive identification through what is now our most accurate means. Proficiency with the methodology, principles, and interpretation of DNA evidence is crucial for today‘s criminalist.

Forensic Analysis of Biological Evidence

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Publisher : CRC Press
ISBN 13 : 1466504587
Total Pages : 176 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Forensic Analysis of Biological Evidence by : J. Thomas McClintock

Download or read book Forensic Analysis of Biological Evidence written by J. Thomas McClintock and published by CRC Press. This book was released on 2017-08-02 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: A powerful tool in the identification of individuals, DNA typing has revolutionized criminal and paternity investigations. Widespread analysis is now conducted by public and private laboratories in the United States and abroad. Focusing on the basic techniques used in forensic DNA laboratories, Forensic Analysis of Biological Evidence: A Laboratory

Forensic DNA Biology

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Publisher : Academic Press
ISBN 13 : 0123948339
Total Pages : 226 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Forensic DNA Biology by : Kelly M. Elkins

Download or read book Forensic DNA Biology written by Kelly M. Elkins and published by Academic Press. This book was released on 2012-08-03 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA typing has revolutionized criminal investigations and has become a powerful tool in the identification of individuals in criminal and paternity cases. Forensic DNA Biology: A Laboratory Manual is comprised of up-to-date and practical experiments and step-by-step instructions on how to perform DNA analysis, including pipetting, microscopy and hair analysis, presumptive testing of body fluids and human DNA typing. Modern DNA typing techniques are provided, reflecting real life, where not all institutions and crime labs can afford the same equipment and software. Real case studies will be used throughout. Provides practical step-by-step instruction on how to perform forensic DNA analysis Includes analysis of hair, presumptive testing of body fluids, human DNA typing and statistics Covers techniques such as pipetting, microscopy and DNA extraction Pre- and post-lab exercises and questions assist the reader in learning the material Report writing templates assure the reader learns real world crime lab procedure

Forensic Biology

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Publisher : CRC Press
ISBN 13 : 1420043447
Total Pages : 435 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Forensic Biology by : Richard Li

Download or read book Forensic Biology written by Richard Li and published by CRC Press. This book was released on 2008-04-24 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed as an accessible introduction to basic scientific principles and their application in professional practice, Forensic Biology provides a concise overview of the field. Focusing solely on the science behind the forensic analysis of biological evidence, this book highlights the principles, methods, and techniques used in forensic sero

Forensic Analysis of Biological Evidence

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Publisher : CRC Press
ISBN 13 : 9781466504608
Total Pages : 176 pages
Book Rating : 4.5/5 (46 download)

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Book Synopsis Forensic Analysis of Biological Evidence by : J. Thomas McClintock

Download or read book Forensic Analysis of Biological Evidence written by J. Thomas McClintock and published by CRC Press. This book was released on 2014 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: A powerful tool in the identification of individuals, DNA typing has revolutionized criminal and paternity investigations. Widespread analysis is now conducted by public and private laboratories in the United States and abroad. Focusing on the basic techniques used in forensic DNA laboratories, Forensic Analysis of Biological Evidence: A Laboratory Guide for Serological and DNA Typing introduces readers to the science of serological analysis and DNA typing methods and provides a thorough background of the molecular techniques used to determine an individual’s identity or parental lineage. Originally published as Forensic DNA Analysis: A Laboratory Manual, this revised work offers updated exercises and protocols for all kinds of DNA and serological analyses with delineated objectives, step-by-step procedures, and required laboratory supplies. Each exercise in this manual: Provides an overview of forensic DNA analysis Explains the sources or types of biological material used in a particular DNA analysis Supplies the background principles and practical methodology for specific serological analysis and DNA typing techniques Simulates human forensic testing and can also be used to simulate a wide range of applications for genetic analysis The book contains an extensive glossary to make readers familiar with terminology used in the forensic analysis of biological evidence, as well as basic terms used in molecular biology. Those who master the material in this volume will understand the methodology of the investigation in DNA typing, develop an understanding of the scientific principles involved in serology and DNA analysis, and succeed in analyzing and interpreting the data generated in each exercise with clarity and confidence.

Principles and Practices of DNA Analysis: A Laboratory Manual for Forensic DNA Typing

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Publisher : Humana
ISBN 13 : 9781071602768
Total Pages : 344 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Principles and Practices of DNA Analysis: A Laboratory Manual for Forensic DNA Typing by : Hirak Ranjan Dash

Download or read book Principles and Practices of DNA Analysis: A Laboratory Manual for Forensic DNA Typing written by Hirak Ranjan Dash and published by Humana. This book was released on 2021-02-21 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents hands-on protocols for conventional and advanced forensic DNA fingerprinting experiments. It includes manual, semi-automatic, and advanced automatic techniques for DNA extraction from different biological samples. It also discusses various qualitative and quantitative approaches for the assessment of extracted forensic DNA. It contains protocols for the amplification of short tandem repeat markers (STRs) for the amplification-based target enrichment of the forensic samples. Further, it examines genotyping of the STR loci through capillary electrophoresis and includes real-world case studies where forensic DNA analysis has been used in the criminal and civil disputes. The book concludes by presenting technological developments in the field of DNA forensic analysis. Suitable for beginners, it is a key reference resource on a wide variety of DNA profiling techniques and applications.

Forensic DNA Profiling

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Publisher : CRC Press
ISBN 13 : 0429671423
Total Pages : 132 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Forensic DNA Profiling by : Jo-Anne Bright

Download or read book Forensic DNA Profiling written by Jo-Anne Bright and published by CRC Press. This book was released on 2019-12-09 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA testing and its forensic analysis are recognized as the “gold standard” in forensic identification science methods. However, there is a great need for a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures, how to assign a likelihood ratio, and how to use the subsequent likelihood ratio when reporting interpretation conclusions. Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios will provide a roadmap for labs all over the world and the next generation of analysts who need this foundational understanding. The techniques used in forensic DNA analysis are based upon the accepted principles of molecular biology. The interpretation of a good-quality DNA profile generated from a crime scene stain from a single-source donor provides an unambiguous result when using the most modern forensic DNA methods. Unfortunately, many crime scene profiles are not single source. They are described as mixed since they contain DNA from two or more individuals. Interpretation of DNA mixtures represents one of the greatest challenges to the forensic DNA analyst. As such, the book introduces terms used to describe DNA profiles and profile interpretation. Chapters explain DNA extraction methods, the polymerase chain reaction (PCR), capillary electrophoresis (CE), likelihood ratios (LRs) and their interpretation, and population genetic models—including Mendelian inheritance and Hardy-Weinberg equilibrium. It is important that analysts understand how LRs are generated in a probabilistic framework, ideally with an appreciation of both semicontinuous and fully continuous probabilistic approaches. KEY FEATURES: • The first book to focus entirely on DNA mixtures and the complexities involved with interpreting the results • Takes a hands-on approach offering theory with worked examples and exercises to be easily understood and implementable by laboratory personnel • New methods, heretofore unpublished previously, provide a means to innovate deconvoluting a mixed DNA profile, assign an LR, and appropriately report the weight of evidence • Includes a chapter on assigning LRs for close relatives (i.e., “It’s not me, it was my brother”), and discusses strategies for the validation of probabilistic genotyping software Forensic DNA Profiling fills the void for labs unfamiliar with LRs, and moving to probabilistic solutions, and for labs already familiar with LRs, but wishing to understand how they are calculated in more detail. The book will be a welcome read for lab professionals and technicians, students, and legal professionals seeking to understand and apply the techniques covered.

An Introduction to Forensic DNA Analysis, Second Edition

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Publisher : CRC Press
ISBN 13 : 9781420058505
Total Pages : 332 pages
Book Rating : 4.0/5 (585 download)

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Book Synopsis An Introduction to Forensic DNA Analysis, Second Edition by : Norah Rudin

Download or read book An Introduction to Forensic DNA Analysis, Second Edition written by Norah Rudin and published by CRC Press. This book was released on 2001-12-21 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant advances in DNA analysis techniques have surfaced since the 1997 publication of the bestselling An Introduction to Forensic DNA Analysis. DNA typing has become increasingly automated and miniaturized. Also, with the advent of Short Tandem Repeat (STR) technology, even the most minute sample of degraded DNA can yield a profile, providing valuable case information. However, just as the judicial system slowly and reluctantly accepted RFLP and AmpliType® PM+DQA1 typing, it is now scrutinizing the admissibility of STRs. Acknowledging STR typing as the current system of choice, An Introduction to Forensic DNA Analysis, Second Edition translates new and established concepts into plain English so that laypeople can gain insight into how DNA analysis works, from sample collection to interpretation of results. In response to the shift toward more efficient techniques, the authors cover the legal admissibility of STR typing, expand the chapter on DNA databases, and revise the section on automated analysis. They also present key decisions and appellate or supreme court rulings that provide precedent at the state and federal levels. Discussing forensic DNA issues from both a scientific and a legal perspective, the authors of An Introduction to Forensic DNA Analysis, Second Edition present the material in a manner understandable by professionals in the legal system, law enforcement, and forensic science. They cover general principles in a clear fashion and include a glossary of terms and other useful appendices for easy reference.

Fundamentals of Forensic DNA Typing

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Publisher : Academic Press
ISBN 13 : 0080961762
Total Pages : 519 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Fundamentals of Forensic DNA Typing by : John M. Butler

Download or read book Fundamentals of Forensic DNA Typing written by John M. Butler and published by Academic Press. This book was released on 2009-09-30 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980’s, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable. Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key

Forensic DNA Typing: Principles, Applications and Advancements

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Publisher : Springer Nature
ISBN 13 : 9811566550
Total Pages : 673 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Forensic DNA Typing: Principles, Applications and Advancements by : Pankaj Shrivastava

Download or read book Forensic DNA Typing: Principles, Applications and Advancements written by Pankaj Shrivastava and published by Springer Nature. This book was released on 2020-12-11 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book explores the fundamental principles, advances in forensic techniques, and its application on forensic DNA analysis. The book is divided into three modules; the first module provides the historical prospect of forensic DNA typing and introduces fundamentals of forensic DNA typing, methodology, and technical advancements, application of STRs, and DNA databases for forensic DNA profile analysis. Module 2 examines the problems and challenges encountered in extracting DNA and generating DNA profiles. It provides information on the methods and the best practices for DNA isolation from forensic biological samples and human remains like ancient DNA, DNA typing of skeletal remains and disaster victim identification, the importance of DNA typing in human trafficking, and various problems associated with capillary electrophoresis. Module 3 emphasizes various technologies that are based on SNPs, STRs namely Y-STR, X-STR, mitochondrial DNA profiling in forensic science. Module 4 explores the application of non-human forensic DNA typing of domestic animals, wildlife forensics, plant DNA fingerprinting, and microbial forensics. The last module discusses new areas and alternative methods in forensic DNA typing, including Next-Generation Sequencing, and its utility in forensic science, oral microbes, and forensic DNA phenotyping. Given its scope, the book is a useful resource in the field of DNA fingerprinting for scientists, forensic experts, and students at the postgraduate level.

The Evaluation of Forensic DNA Evidence

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Publisher : National Academies Press
ISBN 13 : 0309053951
Total Pages : 271 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis The Evaluation of Forensic DNA Evidence by : National Research Council

Download or read book The Evaluation of Forensic DNA Evidence written by National Research Council and published by National Academies Press. This book was released on 1996-12-12 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.

DNA Technology in Forensic Science

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Publisher : National Academies Press
ISBN 13 : 0309185580
Total Pages : 198 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis DNA Technology in Forensic Science by : National Research Council

Download or read book DNA Technology in Forensic Science written by National Research Council and published by National Academies Press. This book was released on 1992-01-01 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Matching DNA samples from crime scenes and suspects is rapidly becoming a key source of evidence for use in our justice system. DNA Technology in Forensic Science offers recommendations for resolving crucial questions that are emerging as DNA typing becomes more widespread. The volume addresses key issues: Quality and reliability in DNA typing, including the introduction of new technologies, problems of standardization, and approaches to certification. DNA typing in the courtroom, including issues of population genetics, levels of understanding among judges and juries, and admissibility. Societal issues, such as privacy of DNA data, storage of samples and data, and the rights of defendants to quality testing technology. Combining this original volume with the new update-The Evaluation of Forensic DNA Evidence-provides the complete, up-to-date picture of this highly important and visible topic. This volume offers important guidance to anyone working with this emerging law enforcement tool: policymakers, specialists in criminal law, forensic scientists, geneticists, researchers, faculty, and students.

DNA Fingerprinting

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Publisher : Oxford University Press
ISBN 13 : 0198044372
Total Pages : 383 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis DNA Fingerprinting by : Lorne T. Kirby

Download or read book DNA Fingerprinting written by Lorne T. Kirby and published by Oxford University Press. This book was released on 1993-09-23 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA fingerprinting is a revolutionary technique that enables scientists to match minute tissue samples and facilitates scientific studies on the composition, reproduction, and evolution of animal and plant populations. As a tool for positive identification of criminals, it plays a particularly important role in forensic science. The first book to be published in the field, , DNA Fingerprinting is a practical guide to basic principles and laboratory methods as applied to a variety of fields including forensic analysis, paternity testing, medical diagnostics, animal and plant sciences, and wildlife poaching.

Understanding Forensic DNA

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Publisher : Cambridge University Press
ISBN 13 : 1009049860
Total Pages : 207 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Understanding Forensic DNA by : Suzanne Bell

Download or read book Understanding Forensic DNA written by Suzanne Bell and published by Cambridge University Press. This book was released on 2022-09-22 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic DNA analysis plays a central role in the judicial system. A DNA sample can change the course of an investigation with immense consequences. Because DNA typing is recognized as the epitome of forensic science, increasing public awareness in this area is vital. Through several cases, examples and illustrations, this book explains the basic principles of forensic DNA typing, and how it integrates with law enforcement investigations and legal decisions. Written for a general readership, Understanding Forensic DNA explains both the power and the limitations of DNA analysis. This book dispels common misunderstandings regarding DNA analysis and shows how astounding match probabilities such as one-in-a-trillion are calculated, what they really mean, and why DNA alone never solves a case.

Crime Laboratory Digest

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Publisher :
ISBN 13 :
Total Pages : 382 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Crime Laboratory Digest by :

Download or read book Crime Laboratory Digest written by and published by . This book was released on 1987 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Forensic DNA Profiling Protocols

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Publisher : Springer Science & Business Media
ISBN 13 : 0896034437
Total Pages : 617 pages
Book Rating : 4.8/5 (96 download)

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Book Synopsis Forensic DNA Profiling Protocols by : Patrick J. Lincoln

Download or read book Forensic DNA Profiling Protocols written by Patrick J. Lincoln and published by Springer Science & Business Media. This book was released on 1998-01-22 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: This state-of-the-art collection of easily reproducible methods includes all of the major techniques of DNA analysis currently used in forensic identity testing. The methods include the recovery of DNA from a large range of sample types, analysis of DNA as single and multi-locus VNTR probes, PCR amplification of STR and other loci, and mitochondrial sequencing. The expert scientists writing here -- many from laboratories around the world -- also discuss how to interpret the results in cases of unknown identity and disputed parentage.-- Covers all steps from extraction of human DNA through to analysis and interpretation-- Takes advantage of new methodologies such as capillary electrophoresis-- Clear step-by-step instructions ensure unfailing reproducibility.