Organ Crosstalk In Acute Kidney Injury

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Organ Crosstalk in Acute Kidney Injury

Author : Carlos Guido Musso
Publisher : Springer Nature
ISBN 13 : 3031367898
Total Pages : 219 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Organ Crosstalk in Acute Kidney Injury by : Carlos Guido Musso

Download or read book Organ Crosstalk in Acute Kidney Injury written by Carlos Guido Musso and published by Springer Nature. This book was released on 2023-10-14 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an original work dedicated to an important and current topic in nephrology: organ crosstalk in acute renal injury. Acute kidney injury is a prevalent and serious syndrome. The related mortality to this syndrome has not been significantly reduced in the last decades despite the advances in renal replacement therapy technology. For this reason, a new approach to obtain an effective treatment is urgently needed. The organ crosstalk perspective could be useful in order to achieve this objective since it implies a very early acute kidney injury diagnose and treatment. This book includes a comprehensive review of the organ crosstalk perspective in acute kidney injury. Organized in two parts, the chapters in the first part present general subjects as an introduction to analysing the crosstalk concept. These chapters give an overview of the concepts of biosemiotics, hormones, neurotransmitters, cytokines, signalling and adhesion molecules, organ intercommunication, and epigenetics. The second part gathers chapters on the different kidney crosstalk, such as brain, lung, heart, liver, gut, and placenta. Finally, there is a chapter dedicated to the influence of renal replacement treatment on kidney crosstalk. Since acute kidney injury is a topic of interest to many health professionals, this work will be a useful resource to general practitioners, internal medicine physicians, geriatricians, nephrologists, critical care therapists, immunologists, and also biologists and bioengineers.

Controversies in Acute Kidney Injury

Author : J.A. Kellum
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805598114
Total Pages : 266 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Controversies in Acute Kidney Injury by : J.A. Kellum

Download or read book Controversies in Acute Kidney Injury written by J.A. Kellum and published by Karger Medical and Scientific Publishers. This book was released on 2011-09-15 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury (AKI) is a serious and as yet incompletely understood disorder in which sudden impairment of kidney function occurs secondary to one or more of a variety of underlying conditions. This disorder is very common in (elderly) ICU patients and is associated with very high mortality. Many of those who survive suffer from permanent kidney failure and other long-term morbidities, which may include cardiovascular disease and immune dysfunction. Epidemiologic evidence suggests that AKI is not a single disease, but a syndrome comprised of multiple, often coexisting, etiologies. Being usually part of multiorgan failure syndrome, it calls for multiple organ support therapy.The publication at hand contains sections on prerenal azotemia syndromes, dying ‘of’ or ‘with’ AKI, pathophysiology of sepsis-induced acute kidney injury, developments in prevention / treatment / rehabilitation, and renal support. Reporting the latest recommendations from experts, it provides valuable information for those that are interested in understanding the disorder and its treatment options.

Kidney and Distant Organ Crosstalk in Health and Disease

Author : Jonatan Barrera-Chimal
Publisher : Frontiers Media SA
ISBN 13 : 2889712699
Total Pages : 164 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Kidney and Distant Organ Crosstalk in Health and Disease by : Jonatan Barrera-Chimal

Download or read book Kidney and Distant Organ Crosstalk in Health and Disease written by Jonatan Barrera-Chimal and published by Frontiers Media SA. This book was released on 2021-09-08 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Textbook of Cardiorenal Medicine

Author : Peter A. McCullough
Publisher : Springer Nature
ISBN 13 : 3030574601
Total Pages : 381 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Textbook of Cardiorenal Medicine by : Peter A. McCullough

Download or read book Textbook of Cardiorenal Medicine written by Peter A. McCullough and published by Springer Nature. This book was released on 2020-11-24 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a practical and board-driven resource to describe and define the emerging field of cardiorenal medicine. Covering all aspects of the topic with depth and relevance, this groundbreaking reference brings together experts at the nexus between cardiovascular and renal medicine to provide an exception reference to educate in this critical area of modern medicine. It describes how the heart and kidneys are inextricably linked via hemodynamic, neural, hormonal and cellular signaling systems and, concentrating on disease-based coverage, goes on to review emerging concepts in epidemiology, pathogenesis, screening, diagnosis and the management of cardiorenal syndromes, all extensively illustrated and containing features to support scholarship in the field. Textbook of Cardiorenal Medicine provides consistent chapter organization, clear design and engaging text to define the diagnosis, treatment, intervention and surgical aspects of the full range of conditions encountered within this area of medicine. It is therefore an essential resource to all involved in the management of cardiorenal disease.

Pediatric Critical Care Medicine

Author : Derek S. Wheeler
Publisher : Springer Science & Business Media
ISBN 13 : 9781846284632
Total Pages : 1854 pages
Book Rating : 4.2/5 (846 download)

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Book Synopsis Pediatric Critical Care Medicine by : Derek S. Wheeler

Download or read book Pediatric Critical Care Medicine written by Derek S. Wheeler and published by Springer Science & Business Media. This book was released on 2007 with total page 1854 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new textbook is the definitive evidence-based resource for pediatric critical care. It is the first ostensibly evidence-based pediatric critical care textbook and will prove an invaluable resource for critical care professionals across the globe.

ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes

Author : J.A. Kellum
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318024074
Total Pages : 216 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes by : J.A. Kellum

Download or read book ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes written by J.A. Kellum and published by Karger Medical and Scientific Publishers. This book was released on 2013-05-14 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Associated with both acute kidney injury (AKI) and cardio-renal syndromes (CRS), new biomarkers represent both a popular area of investigation and a new opportunity for advancement of therapy. This book contains the resolutions of the most recent ADQI conferences on biomarkers in AKI (Dublin) and on cardio-renal syndromes (Venice). The first part answers specific questions about new biomarkers and their use and utility in AKI: What are the most suitable candidate molecules and physiologic measures, how solid and evidence based is the discovery phase? How can we incorporate the new biomarkers in the AKI conceptual model describing the evolution from susceptibility to insult, decreased GFR and organ death? Even if we have a positive biomarker pattern and we can identify patients at risk or patients with early or even subclinical AKI, how is this information affecting our clinical behavior and practice? The second part is dedicated to the appraisal of the current knowledge about the pathophysiological mechanisms involved in different forms of CRS: it contains contributions on the state-of-the-art knowledge and practice of CRS, particularly focusing on the pathophysiology of the five subtypes. Acute and chronic mechanisms of damage are explored in depth, with particular attention to the primacy of organ involvement and the subsequent pathways of organ crosstalk.Presenting the most recent research in the field of biomarkers, AKI and CRS, this publication is an important educational tool for advanced investigators and clinical experts, but also for students and fellows.

Controversies in Acute Kidney Injury

Author : John A. Kellum
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805598106
Total Pages : 267 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Controversies in Acute Kidney Injury by : John A. Kellum

Download or read book Controversies in Acute Kidney Injury written by John A. Kellum and published by Karger Medical and Scientific Publishers. This book was released on 2011 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely update Acute kidney injury (AKI) is a serious and as yet incompletely understood disorder in which sudden impairment of kidney function occurs secondary to one or more of a variety of underlying conditions. This disorder is very common in (elderly) ICU patients and is associated with very high mortality. Many of those who survive suffer from permanent kidney failure and other long-term morbidities, which may include cardiovascular disease and immune dysfunction. Epidemiologic evidence suggests that AKI is not a single disease, but a syndrome comprised of multiple, often coexisting, etiologies. Being usually part of multiorgan failure syndrome, it calls for multiple organ support therapy. The publication at hand contains sections on prerenal azotemia syndromes, dying of' or with' AKI, pathophysiology of sepsis- induced acute kidney injury, developments in prevention / treatment / rehabilitation, and renal support. Reporting the latest recommendations from experts, it provides valuable information for those that are interested in understanding the disorder and its treatment options.

Acute Kidney Injury and Regenerative Medicine

Author : Yoshio Terada
Publisher : Springer Nature
ISBN 13 : 981151108X
Total Pages : 390 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Acute Kidney Injury and Regenerative Medicine by : Yoshio Terada

Download or read book Acute Kidney Injury and Regenerative Medicine written by Yoshio Terada and published by Springer Nature. This book was released on 2020-05-14 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis.Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.

Acute kidney injury

Author : Sics Editore
Publisher : SICS Editore
ISBN 13 : 8869302253
Total Pages : 45 pages
Book Rating : 4.8/5 (693 download)

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Book Synopsis Acute kidney injury by : Sics Editore

Download or read book Acute kidney injury written by Sics Editore and published by SICS Editore. This book was released on 2014-10-01 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt: In acute kidney injury (AKI) the ability of the glomeruli to filtrate deteriorates, which leads to a disturbed acid-base and fluid balance as well as to the accumulation of end products of nitrogen metabolism. Within 24 to 48 hours of the onset of the injury the serum creatinine concentration will rise and urine output fall. AKI should be identified before the creatinine concentration is markedly increased and the estimated glomerular filtration rate (eGFR) falls. A typical patient is an elderly individual with pre-existing renal impairment who, for example, contracts acute diarrhoea or receives nephrotoxic drugs (e.g. NSAIDs, ACE inhibitors), i.e. acute-on-chronic kidney disease. Hypovolaemia is the most common cause of oliguria and can be reversed with fluid therapy. The urine output of a seriously ill patient must be monitored. Urinary retention must be identified and treated. The concomitant administration of an ACE inhibitor, diuretic and NSAID increases the risk of AKI.

Acute Kidney Injury

Author : Claudio Ronco
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805582714
Total Pages : 477 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Acute Kidney Injury by : Claudio Ronco

Download or read book Acute Kidney Injury written by Claudio Ronco and published by Karger Medical and Scientific Publishers. This book was released on 2007-01-01 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury is defined as an abrupt change in serum creatinine and/or urine output, and a majority of patients admitted to the ICU have some evidence of the disorder. Unfortunately, treatment for this complex syndrome is as yet lacking and understanding is limited. An interdisciplinary panel of experts has contributed to this volume, illuminating some of the fundamental and complex aspects of the disorder ranging from pathophysiology to treatment, from emerging biomarkers to genetic polymorphisms. Other contributions focus on immunological issues or the many complications of acute kidney injury and co-morbid conditions encountered, covering the fundamentals as well as the latest developments. Moreover, important technical aspects of extracorporeal therapies including vascular access, anticoagulation or fluid composition are introduced, and different approaches to renal support from intermittent dialysis to continuous therapies and hybrid techniques are discussed. A description of advanced extracorporeal techniques of organ support and their role in the management of sepsis and acute kidney injury in the context of an overall strategy of multi-organ failure management concludes the discussions. This volume not only provides a practical and up-to-date summary of current knowledge and technology, but also imparts a fundamental understanding of the pathogenesis and likely future developments in this field. It also serves to challenge and re-examine the fundamental underlying assumptions we hold regarding critical illness in general and acute kidney injury in particular.

Uremic Toxins

Author : Severin Ringoir
Publisher : Springer Science & Business Media
ISBN 13 : 1468454455
Total Pages : 292 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Uremic Toxins by : Severin Ringoir

Download or read book Uremic Toxins written by Severin Ringoir and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book contains the Proceedings of a two day Symposium on Uremic Toxins organized at the University of Ghent in Belgium. A series of guest lectures, free communications and posters have been presented. An international audience of 163 scientists from 16 nationalities listened to and discussed extensively a spectrum of topics brought forward by colleagues and researchers who worked for many years in the field of Uremic Toxins. There is a striking contrast between all the new dialysis strategies available in the work to "clean" the uremic patients and the almost non-progression of our knowledge on uremic toxins in the past decade. In this sense the symposium was felt by all participants as a new start for the research in the biochemical field of the definition of uremia. If the present volume would stimulate new work in this field in order to define uremia, or identify the uremic toxins, the purpose of the organizers would be maximally fulfilled.

Core Concepts in Acute Kidney Injury

Author : Sushrut S. Waikar
Publisher : Springer
ISBN 13 : 1493986287
Total Pages : 373 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Core Concepts in Acute Kidney Injury by : Sushrut S. Waikar

Download or read book Core Concepts in Acute Kidney Injury written by Sushrut S. Waikar and published by Springer. This book was released on 2018-09-14 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive guide covers the causes, characteristics, and presentations of acute kidney injury (AKI), as well as prevention and treatment. The first part of the book features chapters on the epidemiology and diagnosis of AKI. This is followed by sections on pathophysiology, clinical syndromes and patient management. Authored by leading clinicians, epidemiologists, basic scientists, and clinical trialists, this book captures the latest evidence and best practices for treating patients with AKI.

Acute Kidney Injury: It’s Not Just Acute, and It’s Not Just the Kidneys

Author : Danielle Elise Soranno
Publisher : Frontiers Media SA
ISBN 13 : 2889719987
Total Pages : 99 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Acute Kidney Injury: It’s Not Just Acute, and It’s Not Just the Kidneys by : Danielle Elise Soranno

Download or read book Acute Kidney Injury: It’s Not Just Acute, and It’s Not Just the Kidneys written by Danielle Elise Soranno and published by Frontiers Media SA. This book was released on 2022-01-07 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardiorenal Syndromes in Critical Care

Author : C. Ronco
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805594739
Total Pages : 376 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Cardiorenal Syndromes in Critical Care by : C. Ronco

Download or read book Cardiorenal Syndromes in Critical Care written by C. Ronco and published by Karger Medical and Scientific Publishers. This book was released on 2010-05-04 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical care nephrology is an emerging multidisciplinary science in which the competences of different specialists are merged to provide a unified diagnostic and therapeutic approach to the critically ill patient. The volume at hand places great emphasis on cardiorenal syndromes and the multidisciplinary collaboration between cardiology and nephrology. Several contributions describe the cardiorenal syndrome in its different varieties and subtypes and report the results from the most recent Acute Dialysis Quality Initiative Consensus Conference, as well as proposing new diagnostic approaches based on early biomarkers of AKI. Other papers discuss advances in technology for renal replacement therapy and multiple organ support therapy. Moreover, special emphasis is placed on the potential role of extracorporeal therapies in patients affected by H1N1 influenza, and a summary of the most recent trials in the field is included.Containing the proceedings of the 2010 International Vicenza Course on Critical Care Nephrology, this publication is a state-of-the-art appraisal of today’s technology and current issues related to cardiorenal syndromes.

Brain and Kidney Crosstalk

Author : Hemanshu Prabhakar
Publisher : Springer Nature
ISBN 13 : 9811523258
Total Pages : 126 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Brain and Kidney Crosstalk by : Hemanshu Prabhakar

Download or read book Brain and Kidney Crosstalk written by Hemanshu Prabhakar and published by Springer Nature. This book was released on 2020-06-27 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses normal brain physiology and renal physiology, as well as the interactions between the two. The physiology of the brain can easily be affected by any changes to the physiology of other systems, which in turn may compromise cerebral blood flow and oxygenation. Together the brain and the renal system help our body systems to function automatically. The book addresses the basic aspects of neurophysiology and renal physiology in three broad sections, the first of which covers the basic principles of cerebral physiology and neural regulation of the renal system. The second part reviews the normal physiology of the renal system, including the mechanism of action, while the last section summarizes the correlation between the brain and kidney. Highly informative and clearly structured, the book provides essential insights for anyone with an interest in physiology and medicine.

Critical Care Nephrology E-Book

Author : Claudio Ronco
Publisher : Elsevier Health Sciences
ISBN 13 : 0323511996
Total Pages : 1840 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Critical Care Nephrology E-Book by : Claudio Ronco

Download or read book Critical Care Nephrology E-Book written by Claudio Ronco and published by Elsevier Health Sciences. This book was released on 2017-12-14 with total page 1840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive and clinically relevant, the 3rd Edition of Critical Care Nephrology provides authoritative coverage of the latest advances in critical care procedures for patients with renal diseases or disorders. Using common guidelines and standardized approaches to critically ill patients, this multidisciplinary reference facilitates better communication among all physicians who care for critically ill patients suffering from kidney disease, electrolyte and metabolic imbalances, poisoning, severe sepsis, major organ dysfunction, and other pathological events. Offers detailed discussions of different forms of organ support, artificial organs, infections, acute illness occurring in chronic hemodialysis patients, and much more. Places a special emphasis on therapeutic interventions and treatment procedures for a hands on clinical reference tool. Presents information clearly, in a format designed for easy reference – from basic sciences to clinical syndromes to diagnostic tools. Covers special populations such as children, diabetic patients, and the elderly. An exceptional resource for nephrologists, intensivists, surgeons, or critical care physicians – anyone who treats critically ill renal patients. Shares a combined commitment to excellence lead by Drs. Claudio Ronco, Rinaldo Bellomo, John Kellum, and Zaccaria Ricci – unparalleled leaders in this field. Addresses key topics with expanded coverage of acute kidney injury, stress biomarkers, and sepsis, including the latest developments on mechanisms and management. Provides up-to-date information on extracorporeal therapies from new editor Dr. Zaccaria Ricci.

Acute Kidney Injury - Basic Research and Clinical Practice

Author : X. Ding
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318063118
Total Pages : 166 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Acute Kidney Injury - Basic Research and Clinical Practice by : X. Ding

Download or read book Acute Kidney Injury - Basic Research and Clinical Practice written by X. Ding and published by Karger Medical and Scientific Publishers. This book was released on 2018-01-23 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute Kidney Injury (AKI) is a complex syndrome that is prevalent among hospitalized patients. In recent years, occurrence of AKI events has risen due to a growing susceptibility of fragile and elderly subjects and an increase in the use of complex procedures such as cardiovascular surgery and imaging techniques. Exposure to potentially nephrotoxic drugs, such as new chemotherapeutic agents, is also proving to be a cause of AKI. This book summarizes recent advances in various settings. A reappraisal of current definitions and staging classifications for AKI in the literature is followed by a description of new criteria for identifying patients at risk and characterizing early kidney damage by using biomarkers. Other important topics include the sequelae of AKI and AKI in special populations such as children, the elderly, and those with cancer. The effects of AKI and its consequences on healthcare expenditures are also addressed from several perspectives. AKI management requires the cooperation of different specialists to optimize outcomes. This book is thus a perfect tool not only for nephrologists, but for every specialist involved in the complicated endeavor of improving patient care.