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Acute Kidney Injury And Regenerative Medicine
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Book Synopsis Acute Kidney Injury and Regenerative Medicine by : Yoshio Terada
Download or read book Acute Kidney Injury and Regenerative Medicine written by Yoshio Terada and published by Springer Nature. This book was released on 2020-05-14 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis.Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.
Book Synopsis Regenerative Nephrology by : Michael S. Goligorsky
Download or read book Regenerative Nephrology written by Michael S. Goligorsky and published by Academic Press. This book was released on 2010-11-26 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progression of chronic diseases in general and chronic kidney disease in particular has been traditionally viewed in the light of various contributors to development of glomerulosclerosis and tubulointerstitial scarring culminating in renal fibrosis. Indeed, this dogma prevailed for decades underscoring experimental attempts to halt fibrotic processes. Breakthrough investigations of the past few years on stem/progenitor cell involvement in organ regeneration caused a conceptual shift in tackling the mechanisms of nephrosclerosis. It has become clear that the rate of progression of chronic kidney disease is the net sum of the opposing trends: degenerative fibrotic processes and regenerative repair mechanisms. The latter part of this equation has been by and large ignored for years and only recently attracted investigative attention. This book revisits the problem of kidney disease by focusing on regenerative mechanisms in renal repair and on the ways these regenerative processes can become subverted by an intrinsic disease process eventuating in its progression. Cutting-edge investigations are summarized by the most experienced international team of experts. Presents a comprehensive, translational source for all aspects of renal stem cells, tissue regeneration, and stem cell therapies for renal diseases in one reference work. This will ultimately result in time savings for academic, medical and pharma researchers Experts in the renal stem cell system in kidney repair and regeneration take readers from the bench research to new therapeutic approaches, providing a common language for nephrology researchers, fellows and other stem cell researchers. This enables the discussion of development of stem cells and their use in the repair and regeneration of the kidney
Book Synopsis Regenerative Nephrology by : Michael S. Goligorsky
Download or read book Regenerative Nephrology written by Michael S. Goligorsky and published by Academic Press. This book was released on 2021-06-12 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of this book in 2010, an explosion of spectacular discoveries in the field of regeneration has compelled the current revisit of the field of Regenerative Nephrology. This second edition features subjects as diverse as age and gender influencing regenerative processes; mechanisms and pathways of premature cell senescence affecting kidney regeneration; the ways intrinsic regenerative processes can become subverted by noxious stressors eventuating in disease progression; novel mechanistic and engineering efforts to recreate functional kidney or its component parts; cell reprogramming and reconditioning as emerging tools of future regenerative efforts; and effects of various biologicals on kidney regeneration. These newer additions to the armamentarium of Regenerative Medicine and Nephrology have become an integral part of the second edition of the book. Cutting-edge investigations are summarized by the constellation of the most experienced contributing authors coming together from around the world under the umbrella of the second edition. A significant expansion of section on induced pluripotent cells and trajectories of their differentiation. This will be followed by mechanisms and modalities of cell reprogramming for therapeutic purposes A new section on tissue engineering of the kidney of interest to nephrologists and urologists An entire section dedicated to causes of regenerative failure with the emphasis on recent discoveries of senescent cells in kidney disease, pathologic effects of senescent cells, advents in senotherapies and rejuvenation therapies A vastly expanded section on pharmacotherapies promoting kidney regeneration, trials of engineered organs, manufacturing in regenerative medicine and smooth transition to the clinical trials, with an update on some ethical issues
Book Synopsis Kidney Inflammation, Injury and Regeneration by : Patrick C. Baer
Download or read book Kidney Inflammation, Injury and Regeneration written by Patrick C. Baer and published by . This book was released on 2020 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury (AKI) is still associated with high morbidity and mortality incidence rates, and also bears an elevated risk of subsequent chronic kidney disease. Although the kidney has a remarkable capacity for regeneration after injury and may recover completely depending on the type of renal lesions, the options for clinical intervention are restricted to fluid management and extracorporeal kidney support. The development of novel therapies to prevent AKI, to improve renal regeneration capacity after AKI, and to preserve renal function is urgently needed. The Special Issue covers research articles that investigated the molecular mechanisms of inflammation and injury during different renal pathologies, renal regeneration, diagnostics using new biomarkers, and the effects of different stimuli like medication or bacterial components on isolated renal cells or in vivo models. The Special Issue contains important reviews that consider the current knowledge of cell death and regeneration, inflammation, and the molecular mechanisms of kidney diseases. In addition, the potential of cell-based therapy approaches that use mesenchymal stromal/stem cells or their derivates is summarized. This edition is complemented by reviews that deal with the current data situation on other specific topics like diabetes and diabetic nephropathy or new therapeutic targets.
Book Synopsis Kidney Inflammation, Injury and Regeneration by : Patrick C. Baer
Download or read book Kidney Inflammation, Injury and Regeneration written by Patrick C. Baer and published by MDPI. This book was released on 2020-04-03 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury (AKI) is still associated with high morbidity and mortality incidence rates, and also bears an elevated risk of subsequent chronic kidney disease. Although the kidney has a remarkable capacity for regeneration after injury and may recover completely depending on the type of renal lesions, the options for clinical intervention are restricted to fluid management and extracorporeal kidney support. The development of novel therapies to prevent AKI, to improve renal regeneration capacity after AKI, and to preserve renal function is urgently needed. The Special Issue covers research articles that investigated the molecular mechanisms of inflammation and injury during different renal pathologies, renal regeneration, diagnostics using new biomarkers, and the effects of different stimuli like medication or bacterial components on isolated renal cells or in vivo models. The Special Issue contains important reviews that consider the current knowledge of cell death and regeneration, inflammation, and the molecular mechanisms of kidney diseases. In addition, the potential of cell-based therapy approaches that use mesenchymal stromal/stem cells or their derivates is summarized. This edition is complemented by reviews that deal with the current data situation on other specific topics like diabetes and diabetic nephropathy or new therapeutic targets.
Book Synopsis Core Concepts in Acute Kidney Injury by : Sushrut S. Waikar
Download or read book Core Concepts in Acute Kidney Injury written by Sushrut S. Waikar and published by Springer. This book was released on 2018-09-14 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive guide covers the causes, characteristics, and presentations of acute kidney injury (AKI), as well as prevention and treatment. The first part of the book features chapters on the epidemiology and diagnosis of AKI. This is followed by sections on pathophysiology, clinical syndromes and patient management. Authored by leading clinicians, epidemiologists, basic scientists, and clinical trialists, this book captures the latest evidence and best practices for treating patients with AKI.
Book Synopsis Present and Future Therapies for End-Stage Renal Disease by :
Download or read book Present and Future Therapies for End-Stage Renal Disease written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Present and Future Therapies for End-stage Renal Disease by : Eli A. Friedman
Download or read book Present and Future Therapies for End-stage Renal Disease written by Eli A. Friedman and published by World Scientific. This book was released on 2010 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction and options in therapy / Eli A. Friedman -- ch. 1. Peritoneal dialysis : past and current practices / Mary C. Mallappallil -- ch. 2. Hemodialysis / Yalemzewd Woredekal -- ch. 3. Kidney transplantation / Fasika Tedla -- ch. 4. Home hemodialysis : present and future therapies / Barbara G. Delano -- ch. 5. Hemofiltration / Halim S. Ghali -- ch. 6. Self-care in-center hemodialysis / Susan H. Bray -- ch. 7. Opting for death rather than dialysis in chronic renal failure / Anthony J. Joseph -- ch. 8. Ethical concerns in marketing kidneys / Amy L. Friedman -- ch. 9. The wearable artificial kidney : a new paradigm in the treatment of ESRD / Victor Gura -- ch. 10. Xenotransplantation / Moro O. Salifu, Syed Shah and Subodh Saggi -- ch. 11. Can the bowel serve as a kidney? / Eli A. Friedman
Book Synopsis Kidney Transplantation, Bioengineering, and Regeneration by : Giuseppe Orlando
Download or read book Kidney Transplantation, Bioengineering, and Regeneration written by Giuseppe Orlando and published by Academic Press. This book was released on 2017-06-08 with total page 1252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement. In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney. Focuses on the synergy between renal organ transplantation and regenerative medicine, highlighting the advances within transplantation, bioengineering, regeneration, and repair Educates the transplant community on important regenerative medicine research pertinent to kidney transplantation Develops a shared language for clinicians, surgeons, and basic researchers to reach across the fields of transplantation and regenerative medicine, and facilitate more productive investigation and research Catalogs the technologies being developed and methods being implemented to bioengineer or regenerate kidneys to restore function
Book Synopsis Acute Kidney Injury, An Issue of Critical Care Clinics by : John A. Kellum
Download or read book Acute Kidney Injury, An Issue of Critical Care Clinics written by John A. Kellum and published by Elsevier Health Sciences. This book was released on 2021-03-25 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Critical Care Clinics, guest edited by Drs. John Kellum and Dana Fuhrman, focuses on Acute Kidney Injury. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: Acute Kidney Injury and Disease, AKI in Cardiac Surgery, AKI in Sepsis, Hepatorenal Disease, Cardiorenal Syndrome, Onconephrology, Renal Functional Reserve and more.
Book Synopsis Acute Kidney Injury: It’s Not Just Acute, and It’s Not Just the Kidneys by : Danielle Elise Soranno
Download or read book Acute Kidney Injury: It’s Not Just Acute, and It’s Not Just the Kidneys written by Danielle Elise Soranno and published by Frontiers Media SA. This book was released on 2022-01-07 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Kidney Inflammation, Injury and Regeneration 2020 by : Patrick C Baer
Download or read book Kidney Inflammation, Injury and Regeneration 2020 written by Patrick C Baer and published by Mdpi AG. This book was released on 2021-11-23 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury (AKI) is still associated with high morbidity and mortality incidence rates, and also bears an elevated risk of chronic kidney disease in the sequel. Whereas the kidney has a remarkable capacity for regeneration after injury and may recover completely depending on the type of renal lesions, the options for clinical intervention are restricted to fluid management and extracorporeal kidney support. The development of novel therapies to prevent AKI, to improve renal regeneration capacity after AKI, and to preserve renal function-in both the short- and long-term-is urgently needed. This Special Issue includes papers investigating the pathological mechanisms of renal inflammation and AKI and diagnostics using new biomarkers. Furthermore, experimental in vitro and in vivo studies examining potential new approaches to attenuate kidney dysfunction are included, as well as review articles.
Book Synopsis Kidney Inflammation, Injury and Regeneration 2020 by : Patrick C. Baer
Download or read book Kidney Inflammation, Injury and Regeneration 2020 written by Patrick C. Baer and published by . This book was released on 2021 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury (AKI) is still associated with high morbidity and mortality incidence rates, and also bears an elevated risk of chronic kidney disease in the sequel. Whereas the kidney has a remarkable capacity for regeneration after injury and may recover completely depending on the type of renal lesions, the options for clinical intervention are restricted to fluid management and extracorporeal kidney support. The development of novel therapies to prevent AKI, to improve renal regeneration capacity after AKI, and to preserve renal function--in both the short- and long-term--is urgently needed. This Special Issue includes papers investigating the pathological mechanisms of renal inflammation and AKI and diagnostics using new biomarkers. Furthermore, experimental in vitro and in vivo studies examining potential new approaches to attenuate kidney dysfunction are included, as well as review articles.
Book Synopsis Diagnostics, Risk Factors, Treatment and Outcomes of Acute Kidney Injury in a New Paradigm by : Wisit Cheungpasitporn
Download or read book Diagnostics, Risk Factors, Treatment and Outcomes of Acute Kidney Injury in a New Paradigm written by Wisit Cheungpasitporn and published by MDPI. This book was released on 2020-12-10 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury (AKI) is a frequent clinical syndrome among hospitalized patients, independently associated with both short- and long-term mortality. Previous investigations attempted to identify effective interventions to prevent AKI or promote kidney function recovery in patients with AKI. Most were unsuccessful. Hence, additional studies are required in the field of AKI research. In this Special Issue, we are making a call to action to stimulate researchers and clinicians to submit their studies on AKI conducted in nephrology, internal medicine, critical care, and other disciplines that will provide additional knowledge and skills in the field of AKI research, ultimately to improve patient outcomes.
Book Synopsis Principles of Regenerative Medicine by : Anthony Atala
Download or read book Principles of Regenerative Medicine written by Anthony Atala and published by Academic Press. This book was released on 2010-12-16 with total page 1202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs
Book Synopsis Clinical Regenerative Medicine in Urology by : Bup Wan Kim
Download or read book Clinical Regenerative Medicine in Urology written by Bup Wan Kim and published by Springer. This book was released on 2017-09-14 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multidisciplinary book provides up-to-date information on clinical approaches that combine stem or progenitor cells, biomaterials and scaffolds, growth factors, and other bioactive agents in order to offer improved treatment of urologic disorders including lower urinary tract dysfunction, urinary incontinence, neurogenic bladder, and erectile dysfunction. In providing clinicians and researchers with a broad perspective on the development of regenerative medicine technologies, it will assist in the dissemination of both regenerative medicine principles and a variety of exciting therapeutic options. After an opening section addressing current developments and future perspectives in tissue engineering and regenerative medicine, fundamentals such as cell technologies, biomaterials, bioreactors, bioprinting, and decellularization are covered in detail. The remainder of the book is devoted to the description and evaluation of a range of cell and tissue applications, with individual chapters focusing on the kidney, bladder, urethra, urethral sphincter, and penis and testis.
Book Synopsis Management of Acute Kidney Problems by : Achim Jörres
Download or read book Management of Acute Kidney Problems written by Achim Jörres and published by Springer Science & Business Media. This book was released on 2010-03-11 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney failure is an important clinical area in the intensive care unit setting. An estimated 5–20% of critically ill patients experience an episode of acute kidney failure during the course of their illness, and about 5% of patients admitted to an ICU will eventually require renal replacement therapy. In these patients, in-hospital mortality is extremely high, exceeding 50%. Thus, the early detection and causal treatment of acute kidney problems is vitally important for a successful outcome. Written by internationally renowned experts, this clinical reference offers helpful advice with the most recent information on the definition, epidemiology, pathophysiology, and clinical causes of acute kidney failure as a fundamental prerequisite for prevention of this disorder. Moreover, it also covers differential diagnostic approaches for patients with acute renal failure and provides a detailed outline of important measures for their clinical management. Finally, separate chapters are dedicated to various key aspects related to the adequate delivery of acute renal replacement therapy. It is intended as a helpful guide for all clinicians involved in the care of patients at risk of developing acute kidney problems.
