Mutation Randomness And Evolution

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Mutation, Randomness, and Evolution

Author : Arlin Stoltzfus
Publisher : Oxford University Press
ISBN 13 : 0192582968
Total Pages : 304 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis Mutation, Randomness, and Evolution by : Arlin Stoltzfus

Download or read book Mutation, Randomness, and Evolution written by Arlin Stoltzfus and published by Oxford University Press. This book was released on 2021-04-22 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: What does it mean to say that mutation is random? How does mutation influence evolution? Are mutations merely the raw material for selection to shape adaptations? The author draws on a detailed knowledge of mutational mechanisms to argue that the randomness doctrine is best understood, not as a fact-based conclusion, but as the premise of a neo-Darwinian research program focused on selection. The successes of this research program created a blind spot - in mathematical models and verbal theories of causation - that has stymied efforts to re-think the role of variation. However, recent theoretical and empirical work shows that mutational biases can and do influence the course of evolution, including adaptive evolution, through a first come, first served mechanism. This thought-provoking book cuts through the conceptual tangle at the intersection of mutation, randomness, and evolution, offering a fresh, far-reaching, and testable view of the role of variation as a dispositional evolutionary factor. The arguments will be accessible to philosophers and historians with a serious interest in evolution, as well as to researchers and advanced students of evolution focused on molecules, microbes, evo-devo, and population genetics.

Randomness in Evolution

Author : John Tyler Bonner
Publisher : Princeton University Press
ISBN 13 : 1400846420
Total Pages : 149 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis Randomness in Evolution by : John Tyler Bonner

Download or read book Randomness in Evolution written by John Tyler Bonner and published by Princeton University Press. This book was released on 2013-03-21 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The important role that randomness plays in evolutionary change John Tyler Bonner, one of our most distinguished and insightful biologists, here challenges a central tenet of evolutionary biology. In this concise, elegantly written book, he makes the bold and provocative claim that some biological diversity may be explained by something other than natural selection. With his customary wit and accessible style, Bonner makes an argument for the underappreciated role that randomness—or chance—plays in evolution. Due to the tremendous and enduring influence of Darwin's natural selection, the importance of randomness has been to some extent overshadowed. Bonner shows how the effects of randomness differ for organisms of different sizes, and how the smaller an organism is, the more likely it is that morphological differences will be random and selection may not be involved to any degree. He traces the increase in size and complexity of organisms over geological time, and looks at the varying significance of randomness at different size levels, from microorganisms to large mammals. Bonner also discusses how sexual cycles vary depending on size and complexity, and how the trend away from randomness in higher forms has even been reversed in some social organisms. Certain to provoke lively discussion, Randomness in Evolution is a book that may fundamentally change our understanding of evolution and the history of life.

Chance in Evolution

Author : Grant Ramsey
Publisher : University of Chicago Press
ISBN 13 : 022640191X
Total Pages : 368 pages
Book Rating : 4.2/5 (264 download)

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Book Synopsis Chance in Evolution by : Grant Ramsey

Download or read book Chance in Evolution written by Grant Ramsey and published by University of Chicago Press. This book was released on 2016-10-25 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This illuminating volume explores the effects of chance on evolution, covering diverse perspectives from scientists, philosophers, and historians. The evolution of species, from single-celled organisms to multicellular animals and plants, is the result of a long and highly chancy history. But how profoundly has chance shaped life on earth? And what, precisely, do we mean by chance? Bringing together biologists, philosophers of science, and historians of science, Chance in Evolution is the first book to untangle the far-reaching effects of chance, contingency, and randomness on the evolution of life. The book begins by placing chance in historical context, starting with the ancients and moving through Darwin to contemporary biology. It documents the shifts in our understanding of chance as Darwin’s theory of evolution developed into the modern synthesis, and how the acceptance of chance in Darwinian theory affected theological resistance to it. Other chapters discuss how chance relates to the concepts of genetic drift, mutation, and parallel evolution—as well as recent work in paleobiology and the experimental evolution of microbes. By engaging in collaboration across biology, history, philosophy, and theology, this book offers a comprehensive overview both of the history of chance in evolution and of our current understanding of the impact of chance on life.

Mutation-Driven Evolution

Author : Masatoshi Nei
Publisher : OUP Oxford
ISBN 13 : 0191637815
Total Pages : 256 pages
Book Rating : 4.1/5 (916 download)

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Book Synopsis Mutation-Driven Evolution by : Masatoshi Nei

Download or read book Mutation-Driven Evolution written by Masatoshi Nei and published by OUP Oxford. This book was released on 2013-05-02 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to present a new mechanistic theory of mutation-driven evolution based on recent advances in genomics and evolutionary developmental biology. The theory asserts, perhaps somewhat controversially, that the driving force behind evolution is mutation, with natural selection being of only secondary importance. The word 'mutation' is used to describe any kind of change in DNA such as nucleotide substitution, gene duplication/deletion, chromosomal change, and genome duplication. A brief history of the principal evolutionary theories (Darwinism, mutationism, neo-Darwinism, and neo-mutationism) that preceded the theory of mutation-driven evolution is also presented in the context of the last 150 years of research. However, the core of the book is concerned with recent studies of genomics and the molecular basis of phenotypic evolution, and their relevance to mutation-driven evolution. In contrast to neo-Darwinism, mutation-driven evolution is capable of explaining real examples of evolution such as the evolution of olfactory receptors, sex-determination in animals, and the general scheme of hybrid sterility. In this sense the theory proposed is more realistic than its predecessors, and gives a more logical explanation of various evolutionary events. Mutation-Driven Evolution is suitable for graduate level students as well as professional researchers (both empiricists and theoreticians) in the fields of molecular evolution and population genetics. It assumes that the readers are acquainted with basic knowledge of genetics and molecular biology.

Evolution

Author : James Alan Shapiro
Publisher : Pearson Education
ISBN 13 : 0132780933
Total Pages : 273 pages
Book Rating : 4.1/5 (327 download)

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Book Synopsis Evolution by : James Alan Shapiro

Download or read book Evolution written by James Alan Shapiro and published by Pearson Education. This book was released on 2011 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book proposes an important new paradigm for understanding biological evolution. Shapiro demonstrates why traditional views of evolution are inadequate to explain the latest evidence, and presents an alternative. His information- and systems-based approach integrates advances in symbiogenesis, epigenetics, and saltationism, and points toward an emerging synthesis of physical, information, and biological sciences.

Population Genetics, Molecular Evolution, and the Neutral Theory

Author : Motoo Kimura
Publisher : University of Chicago Press
ISBN 13 : 9780226435633
Total Pages : 736 pages
Book Rating : 4.4/5 (356 download)

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Book Synopsis Population Genetics, Molecular Evolution, and the Neutral Theory by : Motoo Kimura

Download or read book Population Genetics, Molecular Evolution, and the Neutral Theory written by Motoo Kimura and published by University of Chicago Press. This book was released on 1994 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.

The Random Somatic Mutation is not Quite Random

Author : Florentin Smarandache
Publisher : Infinite Study
ISBN 13 :
Total Pages : 4 pages
Book Rating : 4./5 ( download)

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Book Synopsis The Random Somatic Mutation is not Quite Random by : Florentin Smarandache

Download or read book The Random Somatic Mutation is not Quite Random written by Florentin Smarandache and published by Infinite Study. This book was released on 2023-01-01 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research note challenges the idea that Random Somatic Mutations are entirely random, highlighting their non-equiprobable nature and their influence on evolution, involution, or indeterminacy. It recalls the Neutrosophic Theory of Evolution, extending Darwin’s theory, and emphasizes the importance of distinguishing between different senses of ‘random mutation’ in evolutionary theory.

Mutation and Evolution

Author : Ronny C. Woodruff
Publisher : Springer Science & Business Media
ISBN 13 : 9401152101
Total Pages : 561 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Mutation and Evolution by : Ronny C. Woodruff

Download or read book Mutation and Evolution written by Ronny C. Woodruff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although debated since the time of Darwin, the evolutionary role of mutation is still controversial. In over 40 chapters from leading authorities in mutation and evolutionary biology, this book takes a new look at both the theoretical and experimental measurement and significance of new mutation. Deleterious, nearly neutral, beneficial, and polygenic mutations are considered in their effects on fitness, life history traits, and the composition of the gene pool. Mutation is a phenomenon that draws attention from many different disciplines. Thus, the extensive reviews of the literature will be valuable both to established researchers and to those just beginning to study this field. Through up-to-date reviews, the authors provide an insightful overview of each topic and then share their newest ideas and explore controversial aspects of mutation and the evolutionary process. From topics like gonadal mosaicism and mutation clusters to adaptive mutagenesis, mutation in cell organelles, and the level and distribution of DNA molecular changes, the foundation is set for continuing the debate about the role of mutation, fitness, and adaptability. It is a debate that will have profound consequences for our understanding of evolution.

Crumbling Genome

Author : Alexey S. Kondrashov
Publisher : John Wiley & Sons
ISBN 13 : 1118952111
Total Pages : 309 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Crumbling Genome by : Alexey S. Kondrashov

Download or read book Crumbling Genome written by Alexey S. Kondrashov and published by John Wiley & Sons. This book was released on 2017-07-12 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that are caused, exclusively or primarily, by pre ]existing and new mutations in their genomes, including both a wide variety of genetically simple Mendelian diseases and diverse complex diseases such as birth anomalies, diabetes, and schizophrenia. Milder, but still substantial, negative effects of mutations are even more pervasive. As of now, we possess no means of reducing the rate at which mutations appear spontaneously. However, the recent flood of genomic data made possible by next-generation methods of DNA sequencing, enabled scientists to explore the impacts of deleterious mutations on humans with previously unattainable precision and begin to develop approaches to managing them. Written by a leading researcher in the field of evolutionary genetics, Crumbling Genome reviews the current state of knowledge about deleterious mutations and their effects on humans for those in the biological sciences and medicine, as well as for readers with only a general scientific literacy and an interest in human genetics. Provides an extensive introduction to the fundamentals of evolutionary genetics with an emphasis on mutation and selection Discusses the effects of pre-existing and new mutations on human genotypes and phenotypes Provides a comprehensive review of the current state of knowledge in the field and considers crucial unsolved problems Explores key ethical, scientific, and social issues likely to become relevant in the near future as the modification of human germline genotypes becomes technically feasible Crumbling Genome is must-reading for students and professionals in human genetics, genomics, bioinformatics, evolutionary biology, and biological anthropology. It is certain to have great appeal among all those with an interest in the links between genetics and evolution and how they are likely to influence the future of human health, medicine, and society.

A Series of Fortunate Events

Author : Sean B. Carroll
Publisher : Princeton University Press
ISBN 13 : 0691201757
Total Pages : 224 pages
Book Rating : 4.6/5 (912 download)

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Book Synopsis A Series of Fortunate Events by : Sean B. Carroll

Download or read book A Series of Fortunate Events written by Sean B. Carroll and published by Princeton University Press. This book was released on 2020-10-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Fascinating and exhilarating—Sean B. Carroll at his very best."—Bill Bryson, author of The Body: A Guide for Occupants From acclaimed writer and biologist Sean B. Carroll, a rollicking, awe-inspiring story of the surprising power of chance in our lives and the world Why is the world the way it is? How did we get here? Does everything happen for a reason or are some things left to chance? Philosophers and theologians have pondered these questions for millennia, but startling scientific discoveries over the past half century are revealing that we live in a world driven by chance. A Series of Fortunate Events tells the story of the awesome power of chance and how it is the surprising source of all the beauty and diversity in the living world. Like every other species, we humans are here by accident. But it is shocking just how many things—any of which might never have occurred—had to happen in certain ways for any of us to exist. From an extremely improbable asteroid impact, to the wild gyrations of the Ice Age, to invisible accidents in our parents' gonads, we are all here through an astonishing series of fortunate events. And chance continues to reign every day over the razor-thin line between our life and death. This is a relatively small book about a really big idea. It is also a spirited tale. Drawing inspiration from Monty Python, Kurt Vonnegut, and other great thinkers, and crafted by one of today's most accomplished science storytellers, A Series of Fortunate Events is an irresistibly entertaining and thought-provoking account of one of the most important but least appreciated facts of life.

Genetics and Randomness

Author : Anatoly Ruvinsky
Publisher : CRC Press
ISBN 13 : 9781420078879
Total Pages : 160 pages
Book Rating : 4.0/5 (788 download)

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Book Synopsis Genetics and Randomness by : Anatoly Ruvinsky

Download or read book Genetics and Randomness written by Anatoly Ruvinsky and published by CRC Press. This book was released on 2009-07-28 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analyzes Randomness in Major Genetic Processes and Events No matter how far science advances, the proportion of what is knowable to what is random will remain unchanged, and attempts to ignore this critical threshold are futile at best. With the revolutionary explosion in genetic information discovery, it is crucially important to recognize the underlying limitations of scientific prediction in genetics. Genetics and Randomness furthers the understanding of the role randomness plays in critical biological processes. The book also navigates the complex nature of genetic uncertainty from different points of view and at various levels of biological organization. Avoids Unnecessary Technical Details and Specific Terminology Exploring areas ranging from basic quantum mechanics and molecular genetics to modern evolutionary genetics and the philosophy of mathematics, this well-organized text discusses: Spontaneity of mutations and their relation to subatomic randomness Deep links between subatomic fluctuations and long-term macroscopic changes in living organisms The multitude of random events that occur during development Segregation, genetic drift, and natural selection Randomness and uncertainty are not occasional and regretful deviations from the "true" principles upon which life is built. Genetics and Randomness illustrates the ubiquitous nature of randomness as an integral feature of all essential processes, effectively embracing a probabilistic understanding of the phenomena of life.

Virolution

Author : Frank Ryan
Publisher : HarperCollins UK
ISBN 13 : 0007545274
Total Pages : 400 pages
Book Rating : 4.0/5 (75 download)

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Book Synopsis Virolution by : Frank Ryan

Download or read book Virolution written by Frank Ryan and published by HarperCollins UK. This book was released on 2013-11-28 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The extraordinary role of viruses in evolution and how this is revolutionising biology and medicine.

The Neutral Theory of Molecular Evolution

Author : Motoo Kimura
Publisher : Cambridge University Press
ISBN 13 : 9780521317931
Total Pages : 388 pages
Book Rating : 4.3/5 (179 download)

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Book Synopsis The Neutral Theory of Molecular Evolution by : Motoo Kimura

Download or read book The Neutral Theory of Molecular Evolution written by Motoo Kimura and published by Cambridge University Press. This book was released on 1983 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first comprehensive treatment of this subject.

Improbable Destinies

Author : Jonathan B. Losos
Publisher : Penguin
ISBN 13 : 0399184937
Total Pages : 384 pages
Book Rating : 4.3/5 (991 download)

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Book Synopsis Improbable Destinies by : Jonathan B. Losos

Download or read book Improbable Destinies written by Jonathan B. Losos and published by Penguin. This book was released on 2017-08-08 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major new book overturning our assumptions about how evolution works Earth’s natural history is full of fascinating instances of convergence: phenomena like eyes and wings and tree-climbing lizards that have evolved independently, multiple times. But evolutionary biologists also point out many examples of contingency, cases where the tiniest change—a random mutation or an ancient butterfly sneeze—caused evolution to take a completely different course. What role does each force really play in the constantly changing natural world? Are the plants and animals that exist today, and we humans ourselves, inevitabilities or evolutionary flukes? And what does that say about life on other planets? Jonathan Losos reveals what the latest breakthroughs in evolutionary biology can tell us about one of the greatest ongoing debates in science. He takes us around the globe to meet the researchers who are solving the deepest mysteries of life on Earth through their work in experimental evolutionary science. Losos himself is one of the leaders in this exciting new field, and he illustrates how experiments with guppies, fruit flies, bacteria, foxes, and field mice, along with his own work with anole lizards on Caribbean islands, are rewinding the tape of life to reveal just how rapid and predictable evolution can be. Improbable Destinies will change the way we think and talk about evolution. Losos's insights into natural selection and evolutionary change have far-reaching applications for protecting ecosystems, securing our food supply, and fighting off harmful viruses and bacteria. This compelling narrative offers a new understanding of ourselves and our role in the natural world and the cosmos.

Not by Chance!

Author : Lee M. Spetner
Publisher :
ISBN 13 : 9781880582244
Total Pages : 0 pages
Book Rating : 4.5/5 (822 download)

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Book Synopsis Not by Chance! by : Lee M. Spetner

Download or read book Not by Chance! written by Lee M. Spetner and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author criticies neo-Darwinism and suggests replacing it with "the nonrandom evolutionary hypothesis (NREH)"--p. 209.

Some Assembly Required

Author : Neil Shubin
Publisher : Vintage
ISBN 13 : 1101871342
Total Pages : 289 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Some Assembly Required by : Neil Shubin

Download or read book Some Assembly Required written by Neil Shubin and published by Vintage. This book was released on 2020-03-17 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exciting and accessible new view of the evolution of human and animal life on Earth. From the author of national bestseller, Your Inner Fish, this extraordinary journey of discovery spans centuries, as explorers and scientists seek to understand the origins of life's immense diversity. “Fossils, DNA, scientists with a penchant for suits of armor—what’s not to love?”—BBC Wildlife Magazine Over billions of years, ancient fish evolved to walk on land, reptiles transformed into birds that fly, and apelike primates evolved into humans that walk on two legs, talk, and write. For more than a century, paleontologists have traveled the globe to find fossils that show how such changes have happened. We have now arrived at a remarkable moment—prehistoric fossils coupled with new DNA technology have given us the tools to answer some of the basic questions of our existence: How do big changes in evolution happen? Is our presence on Earth the product of mere chance? This new science reveals a multibillion-year evolutionary history filled with twists and turns, trial and error, accident and invention. In Some Assembly Required, Neil Shubin takes readers on a journey of discovery spanning centuries, as explorers and scientists seek to understand the origins of life's immense diversity.

The Edge of Evolution

Author : Michael J. Behe
Publisher : Simon and Schuster
ISBN 13 : 0743296222
Total Pages : 339 pages
Book Rating : 4.7/5 (432 download)

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Book Synopsis The Edge of Evolution by : Michael J. Behe

Download or read book The Edge of Evolution written by Michael J. Behe and published by Simon and Schuster. This book was released on 2008-06-17 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author of Darwin's Black Box draws on new findings in genetics to pose an argument for intelligent design that refutes Darwinian beliefs about evolution while offering alternative analyses of such factors as disease, random mutations, and the human struggle for survival. Reprint. 40,000 first printing.