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The Random Somatic Mutation Is Not Quite Random
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Book Synopsis The Random Somatic Mutation is not Quite Random by : Florentin Smarandache
Download or read book The Random Somatic Mutation is not Quite Random written by Florentin Smarandache and published by Infinite Study. This book was released on 2023-01-01 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research note challenges the idea that Random Somatic Mutations are entirely random, highlighting their non-equiprobable nature and their influence on evolution, involution, or indeterminacy. It recalls the Neutrosophic Theory of Evolution, extending Darwin’s theory, and emphasizes the importance of distinguishing between different senses of ‘random mutation’ in evolutionary theory.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309452880 Total Pages :329 pages Book Rating :4.3/5 (94 download)
Book Synopsis Human Genome Editing by : National Academies of Sciences, Engineering, and Medicine
Download or read book Human Genome Editing written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-08-13 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Evolution written by James Alan Shapiro and published by Pearson Education. This book was released on 2011 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book proposes an important new paradigm for understanding biological evolution. Shapiro demonstrates why traditional views of evolution are inadequate to explain the latest evidence, and presents an alternative. His information- and systems-based approach integrates advances in symbiogenesis, epigenetics, and saltationism, and points toward an emerging synthesis of physical, information, and biological sciences.
Book Synopsis Genetics for Surgeons by : Patrick John Morrison
Download or read book Genetics for Surgeons written by Patrick John Morrison and published by Remedica. This book was released on 2005 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Morrison (human genetics, University of Ulster, UK) and Spence (biomedical science, University of Ulster, UK) offer an accessible reference on the genetic disorders that surgeons can expect to meet in general surgical practice. Written in non-technical language, with a glossary, list of abbreviations, and color and b&w photos and medical images, the book supplies an introduction to the nomenclature and technology of molecular biology, and will be a useful starting point for those who wish to extend their knowledge. Annotation :2005 Book News, Inc., Portland, OR (booknews.com).
Book Synopsis Tumour Viruses of Murine Origin by : G. E. W. Wolstenholme
Download or read book Tumour Viruses of Murine Origin written by G. E. W. Wolstenholme and published by John Wiley & Sons. This book was released on 2009-09-16 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Book Synopsis Rheumatism in Populations by : J. S. Lawrence
Download or read book Rheumatism in Populations written by J. S. Lawrence and published by Elsevier. This book was released on 2016-06-03 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rheumatism in Populations provides information pertinent to rheumatic diseases. This book covers certain systemic orders such as the systemic lupus erythematosus that frequently affect the joints. Organized into 16 chapters, this book begins with an overview of the history of the epidemiology of rheumatism. This text then examines the prevalence of rheumatoid arthritis in screened sample and in total population samples. Other chapters consider the relative significance of rheumatic disorders as a cause of loss of work as revealed by the National Health Insurance statistics. This book discusses as well the pathology of disc disorders, osteoarthritis, rheumatoid arthritis, benign polyarthritis, metabolic joint disease, general connective tissue diseases, and immune deficiency diseases. The final chapter deals with diagnostic criteria for population investigations of rheumatoid arthritis. This book is a valuable resource for rheumatologists, physicians, and medico-social workers. Readers who are interested in the study of rheumatic diseases will also find this book useful.
Download or read book Brookhaven Symposia in Biology written by and published by . This book was released on 1948 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Genetics of Cancer by : B.A. Ponder
Download or read book The Genetics of Cancer written by B.A. Ponder and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.
Book Synopsis Molecular Biology of B Cells by : Tasuku Honjo
Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Elsevier. This book was released on 2014-10-09 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. Covers signaling mechanisms regulating B cell differentiation Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab Contains studies on B cell tumors from various stages of B lymphocytes Offers an integrated view of all aspects of B cells to produce a normal immune response
Book Synopsis Genomics, Circuits, and Pathways in Clinical Neuropsychiatry by : Thomas Lehner
Download or read book Genomics, Circuits, and Pathways in Clinical Neuropsychiatry written by Thomas Lehner and published by Academic Press. This book was released on 2016-06-07 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt: This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics Identifies key concepts, methods, and findings Includes coverage of multiple disorders from autism to schizophrenia Reviews specific genes associated with disorders Discusses the genetic architecture of these syndromes Explains how recent findings are influencing the understanding of biology Clarifies the promise of these findings for future treatment
Book Synopsis Comparative Mammalian Immunology by : Ian R Tizard
Download or read book Comparative Mammalian Immunology written by Ian R Tizard and published by Elsevier. This book was released on 2023-02-09 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals provides a review on the current knowledge of mammalian immune systems from a comparative viewpoint. This reference encompasses recent work on the immune systems of marine mammals, bats and marsupials in addition to other lesser-known species, with the immune systems of humans and laboratory mice as components of chapters on primates and rodents respectively. The book also makes use of the most recent studies on the genomic sequences of the mammals to identify both common and unique features of each mammal's immune system. The book elucidates the complex, but coordinated and controlled series of interactions involving cells and molecules that has evolved to protect the host against disease. Mammals consist of a highly diverse group of animals in which the immune system has been subjected to a variety of selective pressures. This is reflected in differences in the organization and function of their immune systems, and is especially seen in those gene families characterized by complexity and polymorphism. Demonstrates multiple diverse pathways and mechanisms to optimize resistance and survival in the face of infectious diseases Shows the clear patterns of emergence of different immunologic traits among the diverse orders of mammals Reflects issues with innate or adaptive immune systems Serves as a comprehensive review of the current state of knowledge of the immune system of each mammalian order
Book Synopsis Antigen Binding Molecules: Antibodies and T-Cell Receptors by :
Download or read book Antigen Binding Molecules: Antibodies and T-Cell Receptors written by and published by Academic Press. This book was released on 1996-12-13 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topics Covered Include: X-ray crystallography of ligands. Catalytic antibodies. Nature of the antigen. Antibody binding sites. Maturation of the immune response. Computational biochemistry of antibodies and T-cell receptors. Antigen-specific T-cell receptors and their reactions. Key Features * X-Ray Crystallography of Ligands * Catalytic Antibodies * Nature of the Antigen * Antibody Binding Sites * Maturtion of the Immune Response * Computational Biochemistry of Antibodies and * T-Cell Receptors * Antigen-Specific T-Cell Receptors and Their Reactions
Book Synopsis Self and Not-Self by : Macfarlane Burnet
Download or read book Self and Not-Self written by Macfarlane Burnet and published by CUP Archive. This book was released on 1969-06-02 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Textbook of Immunology by : Latha, Madhavee P.
Download or read book A Textbook of Immunology written by Latha, Madhavee P. and published by S. Chand Publishing. This book was released on 2012 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: A TEXTBOOK OF IMMUNOLOGY
Book Synopsis Stem Cell Genetic Fidelity by : James L Sherley
Download or read book Stem Cell Genetic Fidelity written by James L Sherley and published by Frontiers Media SA. This book was released on 2015-07-03 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vision of this Frontiers in Oncology Research Topic on “Stem Cell Genetic Fidelity” had the goal of steeping a diverse range of research perspectives to a first comprehensive synthesis of thought on the questions of how tissue stem cells manage gene mutation rate and the significance of that management in mammalian evolution and biology, in particular as it relates to tissue cell renewal, carcinogenesis, and aging. The primary focus was determinants of mutation rate in distributed stem cells (DSCs), which encompass all naturally occurring stem cells at all stages of mammalian development. In particular, contributions were sought that considered a broad range of aspects of the immortal DNA strand hypothesis for DSC genetic fidelity. Though proposed in 1975, only in the last decade has this landmark concept in tissue cell biology emerged as a central discussion in DSC research with increasing scrutiny and discussion by an increasing number of laboratories of diverse research perspectives and experimental approaches. With this hypothesis presenting a formidable technical challenge for experimental investigation, as would be expected, both supportive and unsupportive reports have been lining up. In the case of supportive studies, neither the range of applicable tissues nor the responsible molecular mechanisms are known; and the essential genomic process, non-random DNA template strand inheritance by asymmetrically self-renewing DSCs, has been suggested to potentially have other cellular roles besides reducing mutation rate. A major aspiration of this Research Topic was to create the first comprehensive, critical synthesis of current insights and viewpoints on the impact of the immortal DNA strand hypothesis in the history of DSC mutation research. A wide range of article types was considered including historical perspectives, critical reviews, critical commentaries, new hypotheses, new research perspectives, technical advances, and original research reports. Although treatments of the immortal DNA strand hypothesis were the major focus, the desired synthesis required integration of related ideas on mechanisms of DSC mutagenesis and its impact in the evolution of mammals, the emergence of cancers, and stem cell aging. As such, investigators focused on issues in e.g., germ stem cell mutagenesis, effects of environmental mutagens on DSC mutation rate, DSC mutation and tissue aging, determinations of types of mutations in DSCs, and the role of DSC mutation in cancer initiation were invited. Similarly, although the specific goal of the Research Topic was to enlighten DSC genetic fidelity in humans and other mammalians, informing contributions based on studies in other model organisms were also welcomed. To achieve even better representation of current experience, advances, and ideas in this field of investigation, these early contributors were encouraged to extend the opportunity to others who shared their interest in advancing our understanding of the mutability of DSCs and its significance in human biology.
Book Synopsis Candid Science II by : István Hargittai
Download or read book Candid Science II written by István Hargittai and published by World Scientific. This book was released on 2002-03-15 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable book contains 36 interviews, including 26 with Nobel laureates. It presents a cross-section of biomedical science, a field that has been dominant in science for the past half century. The in-depth conversations cover important research areas and discoveries, as well as the roads to these discoveries, including aspects of the scientists' work that never saw publication. They also bring out the humanness of the famous scientists — the reader learns about their backgrounds, aspirations, failings, and triumphs. The book is illustrated with snapshots of the conversations and photos provided by the interviewees. It is a follow-up to the critically acclaimed Candid Science: Conversations with Famous Chemists, by the same author. Contents: James D WatsonMaclyn McCartyJoshua LederbergArthur KornbergFrederick SangerFrançois JacobWalter Gilbert Benno Müller-HillMarshall W NirenbergDaniel NathansPaul Berg Kary B MullisGerald M EdelmanCésar MilsteinAlfred G GilmanGünter BlobelGeorge K RaddaMax F PerutzRichard HendersonAaron KlugJohn T FinchSidney AltmanEdward B LewisRita Levi-MontalciniLars ErnsterTorvard C LaurentGeorge KleinD Carleton GajdusekCharles WeissmannFrederick C RobbinsRosalyn YalowJames W BlackK Sune D BergströmJohn R VaneSalvador MoncadaRobert F Furchgott Readership: Biomedical scientists, biochemists, and general readers. Reviews:“The book is easy to read … Overall, they give an accurate flavor of biomedical research …”Choice “The present selection of interviews gives a cross section covering a broad range of topics, personalities, and circumstances of recording. I agree with Hargittai's evaluation and heartily recommend his book, suitable for both complete reading or browsing, to biomedical scientists, biochemists, chemists, historians of chemistry and or science, and general readers interested in the 'inside story' of the workings of 20th-century science.”The Chemical Educator “I heartily recommend this book, suitable for both complete reading or browsing, to biomedical scientists, biochemists, chemists, historians of chemistry and of science generally, and general readers interested in the 'inside story' of the workings of 20th-century science.”Chemical Heritage
