Mutation Driven Evolution

Download Mutation Driven Evolution full books in PDF, epub, and Kindle. Read online Mutation Driven Evolution ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Mutation-Driven Evolution

Author : Masatoshi Nei
Publisher : OUP Oxford
ISBN 13 : 0191637815
Total Pages : 256 pages
Book Rating : 4.1/5 (916 download)

DOWNLOAD NOW!

Book Synopsis Mutation-Driven Evolution by : Masatoshi Nei

Download or read book Mutation-Driven Evolution written by Masatoshi Nei and published by OUP Oxford. This book was released on 2013-05-02 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to present a new mechanistic theory of mutation-driven evolution based on recent advances in genomics and evolutionary developmental biology. The theory asserts, perhaps somewhat controversially, that the driving force behind evolution is mutation, with natural selection being of only secondary importance. The word 'mutation' is used to describe any kind of change in DNA such as nucleotide substitution, gene duplication/deletion, chromosomal change, and genome duplication. A brief history of the principal evolutionary theories (Darwinism, mutationism, neo-Darwinism, and neo-mutationism) that preceded the theory of mutation-driven evolution is also presented in the context of the last 150 years of research. However, the core of the book is concerned with recent studies of genomics and the molecular basis of phenotypic evolution, and their relevance to mutation-driven evolution. In contrast to neo-Darwinism, mutation-driven evolution is capable of explaining real examples of evolution such as the evolution of olfactory receptors, sex-determination in animals, and the general scheme of hybrid sterility. In this sense the theory proposed is more realistic than its predecessors, and gives a more logical explanation of various evolutionary events. Mutation-Driven Evolution is suitable for graduate level students as well as professional researchers (both empiricists and theoreticians) in the fields of molecular evolution and population genetics. It assumes that the readers are acquainted with basic knowledge of genetics and molecular biology.

Virolution

Author : Frank Ryan
Publisher : HarperCollins UK
ISBN 13 : 0007545274
Total Pages : 400 pages
Book Rating : 4.0/5 (75 download)

DOWNLOAD NOW!

Book Synopsis Virolution by : Frank Ryan

Download or read book Virolution written by Frank Ryan and published by HarperCollins UK. This book was released on 2013-11-28 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The extraordinary role of viruses in evolution and how this is revolutionising biology and medicine.

Crumbling Genome

Author : Alexey S. Kondrashov
Publisher : John Wiley & Sons
ISBN 13 : 1118952111
Total Pages : 309 pages
Book Rating : 4.1/5 (189 download)

DOWNLOAD NOW!

Book Synopsis Crumbling Genome by : Alexey S. Kondrashov

Download or read book Crumbling Genome written by Alexey S. Kondrashov and published by John Wiley & Sons. This book was released on 2017-07-12 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that are caused, exclusively or primarily, by pre ]existing and new mutations in their genomes, including both a wide variety of genetically simple Mendelian diseases and diverse complex diseases such as birth anomalies, diabetes, and schizophrenia. Milder, but still substantial, negative effects of mutations are even more pervasive. As of now, we possess no means of reducing the rate at which mutations appear spontaneously. However, the recent flood of genomic data made possible by next-generation methods of DNA sequencing, enabled scientists to explore the impacts of deleterious mutations on humans with previously unattainable precision and begin to develop approaches to managing them. Written by a leading researcher in the field of evolutionary genetics, Crumbling Genome reviews the current state of knowledge about deleterious mutations and their effects on humans for those in the biological sciences and medicine, as well as for readers with only a general scientific literacy and an interest in human genetics. Provides an extensive introduction to the fundamentals of evolutionary genetics with an emphasis on mutation and selection Discusses the effects of pre-existing and new mutations on human genotypes and phenotypes Provides a comprehensive review of the current state of knowledge in the field and considers crucial unsolved problems Explores key ethical, scientific, and social issues likely to become relevant in the near future as the modification of human germline genotypes becomes technically feasible Crumbling Genome is must-reading for students and professionals in human genetics, genomics, bioinformatics, evolutionary biology, and biological anthropology. It is certain to have great appeal among all those with an interest in the links between genetics and evolution and how they are likely to influence the future of human health, medicine, and society.

My Life As a Molecular Evolutionist

Author : Masatoshi Nei
Publisher :
ISBN 13 : 9781034958383
Total Pages : pages
Book Rating : 4.9/5 (583 download)

DOWNLOAD NOW!

Book Synopsis My Life As a Molecular Evolutionist by : Masatoshi Nei

Download or read book My Life As a Molecular Evolutionist written by Masatoshi Nei and published by . This book was released on 2022-02-05 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Renowned molecular evolutionist, Masatoshi Nei, recounts his time growing up in Japan and later conducting research on molecular evolution in both Japan and the United States. He also discusses the origin and development of molecular evolution, including some of the joys and disappointments in working in the field. He emphasizes the importance of international collaboration in advancing scientific research and shows how he succeeded.

Genetics of Adaptation

Author : Rodney Mauricio
Publisher : Springer Science & Business Media
ISBN 13 : 1402038364
Total Pages : 209 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!

Book Synopsis Genetics of Adaptation by : Rodney Mauricio

Download or read book Genetics of Adaptation written by Rodney Mauricio and published by Springer Science & Business Media. This book was released on 2006-03-30 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: An enduring controversy in evolutionary biology is the genetic basis of adaptation. Darwin emphasized "many slight differences" as the ultimate source of variation to be acted upon by natural selection. In the early 1900’s, this view was opposed by "Mendelian geneticists", who emphasized the importance of "macromutations" in evolution. The Modern Synthesis resolved this controversy, concluding that mutations in genes of very small effect were responsible for adaptive evolution. A decade ago, Allen Orr and Jerry Coyne reexamined the evidence for this neo-Darwinian view and found that both the theoretical and empirical basis for it were weak. Orr and Coyne encouraged evolutionary biologists to reexamine this neglected question: what is the genetic basis of adaptive evolution? In this volume, a new generation of biologists have taken up this challenge. Using advances in both molecular genetic and statistical techniques, evolutionary geneticists have made considerable progress in this emerging field. In this volume, a diversity of examples from plant and animal studies provides valuable information for those interested in the genetics and evolution of complex traits.

Molecular and Genome Evolution

Author : Dan Graur
Publisher : Sinauer
ISBN 13 : 9781605354699
Total Pages : 0 pages
Book Rating : 4.3/5 (546 download)

DOWNLOAD NOW!

Book Synopsis Molecular and Genome Evolution by : Dan Graur

Download or read book Molecular and Genome Evolution written by Dan Graur and published by Sinauer. This book was released on 2015-01-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the driving forces behind the evolutionary process at the molecular and genome levels, the effects of the various molecular mechanisms on the structure of genes, proteins, and genomes, the methodology and the analytical tools involved in dealing with molecular data from an evolutionary perspective, and the logic of evolutionary hypothesis testing. Evolutionary phenomena at the molecular level are detailed in a way that can be understood without much prerequisite knowledge of molecular biology, evolution, or mathematics. Numerous examples that support and clarify the theoretical arguments and methodological discussions are included.

The mutation theory : experiments and observations on the origin of species in the vegetable kingdom

Author : Hugo de Vries
Publisher :
ISBN 13 :
Total Pages : 708 pages
Book Rating : 4.E/5 ( download)

DOWNLOAD NOW!

Book Synopsis The mutation theory : experiments and observations on the origin of species in the vegetable kingdom by : Hugo de Vries

Download or read book The mutation theory : experiments and observations on the origin of species in the vegetable kingdom written by Hugo de Vries and published by . This book was released on 1910 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Neutral Theory of Molecular Evolution

Author : Motoo Kimura
Publisher : Cambridge University Press
ISBN 13 : 9780521317931
Total Pages : 388 pages
Book Rating : 4.3/5 (179 download)

DOWNLOAD NOW!

Book Synopsis The Neutral Theory of Molecular Evolution by : Motoo Kimura

Download or read book The Neutral Theory of Molecular Evolution written by Motoo Kimura and published by Cambridge University Press. This book was released on 1983 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first comprehensive treatment of this subject.

Genetics and Evolution of Infectious Diseases

Author : Michel Tibayrenc
Publisher : Elsevier
ISBN 13 : 0123848903
Total Pages : 773 pages
Book Rating : 4.1/5 (238 download)

DOWNLOAD NOW!

Book Synopsis Genetics and Evolution of Infectious Diseases by : Michel Tibayrenc

Download or read book Genetics and Evolution of Infectious Diseases written by Michel Tibayrenc and published by Elsevier. This book was released on 2010-12-17 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field

Evolution

Author : James Alan Shapiro
Publisher : Pearson Education
ISBN 13 : 0132780933
Total Pages : 273 pages
Book Rating : 4.1/5 (327 download)

DOWNLOAD NOW!

Book Synopsis Evolution by : James Alan Shapiro

Download or read book Evolution written by James Alan Shapiro and published by Pearson Education. This book was released on 2011 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book proposes an important new paradigm for understanding biological evolution. Shapiro demonstrates why traditional views of evolution are inadequate to explain the latest evidence, and presents an alternative. His information- and systems-based approach integrates advances in symbiogenesis, epigenetics, and saltationism, and points toward an emerging synthesis of physical, information, and biological sciences.

Evolutionary Dynamics

Author : Martin A. Nowak
Publisher : Harvard University Press
ISBN 13 : 0674417755
Total Pages : 377 pages
Book Rating : 4.6/5 (744 download)

DOWNLOAD NOW!

Book Synopsis Evolutionary Dynamics by : Martin A. Nowak

Download or read book Evolutionary Dynamics written by Martin A. Nowak and published by Harvard University Press. This book was released on 2006-09-29 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: At a time of unprecedented expansion in the life sciences, evolution is the one theory that transcends all of biology. Any observation of a living system must ultimately be interpreted in the context of its evolution. Evolutionary change is the consequence of mutation and natural selection, which are two concepts that can be described by mathematical equations. Evolutionary Dynamics is concerned with these equations of life. In this book, Martin A. Nowak draws on the languages of biology and mathematics to outline the mathematical principles according to which life evolves. His work introduces readers to the powerful yet simple laws that govern the evolution of living systems, no matter how complicated they might seem. Evolution has become a mathematical theory, Nowak suggests, and any idea of an evolutionary process or mechanism should be studied in the context of the mathematical equations of evolutionary dynamics. His book presents a range of analytical tools that can be used to this end: fitness landscapes, mutation matrices, genomic sequence space, random drift, quasispecies, replicators, the Prisoner’s Dilemma, games in finite and infinite populations, evolutionary graph theory, games on grids, evolutionary kaleidoscopes, fractals, and spatial chaos. Nowak then shows how evolutionary dynamics applies to critical real-world problems, including the progression of viral diseases such as AIDS, the virulence of infectious agents, the unpredictable mutations that lead to cancer, the evolution of altruism, and even the evolution of human language. His book makes a clear and compelling case for understanding every living system—and everything that arises as a consequence of living systems—in terms of evolutionary dynamics.

The Secret of Our Success

Author : Joseph Henrich
Publisher : Princeton University Press
ISBN 13 : 0691178437
Total Pages : 464 pages
Book Rating : 4.6/5 (911 download)

DOWNLOAD NOW!

Book Synopsis The Secret of Our Success by : Joseph Henrich

Download or read book The Secret of Our Success written by Joseph Henrich and published by Princeton University Press. This book was released on 2017-10-17 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: How our collective intelligence has helped us to evolve and prosper Humans are a puzzling species. On the one hand, we struggle to survive on our own in the wild, often failing to overcome even basic challenges, like obtaining food, building shelters, or avoiding predators. On the other hand, human groups have produced ingenious technologies, sophisticated languages, and complex institutions that have permitted us to successfully expand into a vast range of diverse environments. What has enabled us to dominate the globe, more than any other species, while remaining virtually helpless as lone individuals? This book shows that the secret of our success lies not in our innate intelligence, but in our collective brains—on the ability of human groups to socially interconnect and learn from one another over generations. Drawing insights from lost European explorers, clever chimpanzees, mobile hunter-gatherers, neuroscientific findings, ancient bones, and the human genome, Joseph Henrich demonstrates how our collective brains have propelled our species' genetic evolution and shaped our biology. Our early capacities for learning from others produced many cultural innovations, such as fire, cooking, water containers, plant knowledge, and projectile weapons, which in turn drove the expansion of our brains and altered our physiology, anatomy, and psychology in crucial ways. Later on, some collective brains generated and recombined powerful concepts, such as the lever, wheel, screw, and writing, while also creating the institutions that continue to alter our motivations and perceptions. Henrich shows how our genetics and biology are inextricably interwoven with cultural evolution, and how culture-gene interactions launched our species on an extraordinary evolutionary trajectory. Tracking clues from our ancient past to the present, The Secret of Our Success explores how the evolution of both our cultural and social natures produce a collective intelligence that explains both our species' immense success and the origins of human uniqueness.

Beyond Natural Selection

Author : Robert G. Wesson
Publisher : MIT Press
ISBN 13 : 9780262731027
Total Pages : 382 pages
Book Rating : 4.7/5 (31 download)

DOWNLOAD NOW!

Book Synopsis Beyond Natural Selection by : Robert G. Wesson

Download or read book Beyond Natural Selection written by Robert G. Wesson and published by MIT Press. This book was released on 1993 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: proposes an approach to evolution that is more in harmony with modern science than Darwinism or neo-Darwinism

Evolution as Computation

Author : Laura F. Landweber
Publisher : Springer Science & Business Media
ISBN 13 : 364255606X
Total Pages : 333 pages
Book Rating : 4.6/5 (425 download)

DOWNLOAD NOW!

Book Synopsis Evolution as Computation by : Laura F. Landweber

Download or read book Evolution as Computation written by Laura F. Landweber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of the genetic basis for evolution has flourished in this century, as well as our understanding of the evolvability and programmability of biological systems. Genetic algorithms meanwhile grew out of the realization that a computer program could use the biologically-inspired processes of mutation, recombination, and selection to solve hard optimization problems. Genetic and evolutionary programming provide further approaches to a wide variety of computational problems. A synthesis of these experiences reveals fundamental insights into both the computational nature of biological evolution and processes of importance to computer science. Topics include biological models of nucleic acid information processing and genome evolution; molecules, cells, and metabolic circuits that compute logical relationships; the origin and evolution of the genetic code; and the interface with genetic algorithms and genetic and evolutionary programming.

The Selfish Gene

Author : Richard Dawkins
Publisher : Oxford University Press, USA
ISBN 13 : 9780192860927
Total Pages : 372 pages
Book Rating : 4.8/5 (69 download)

DOWNLOAD NOW!

Book Synopsis The Selfish Gene by : Richard Dawkins

Download or read book The Selfish Gene written by Richard Dawkins and published by Oxford University Press, USA. This book was released on 1989 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science

Evolution, Games, and God

Author : Martin A. Nowak
Publisher : Harvard University Press
ISBN 13 : 0674075536
Total Pages : 398 pages
Book Rating : 4.6/5 (74 download)

DOWNLOAD NOW!

Book Synopsis Evolution, Games, and God by : Martin A. Nowak

Download or read book Evolution, Games, and God written by Martin A. Nowak and published by Harvard University Press. This book was released on 2013-05-07 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the reigning competition-driven model of evolution, selfish behaviors that maximize an organism’s reproductive potential offer a fitness advantage over self-sacrificing behaviors—rendering unselfish behavior for the sake of others a mystery that requires extra explanation. Evolution, Games, and God addresses this conundrum by exploring how cooperation, working alongside mutation and natural selection, plays a critical role in populations from microbes to human societies. Inheriting a tendency to cooperate, argue the contributors to this book, may be as beneficial as the self-preserving instincts usually thought to be decisive in evolutionary dynamics. Assembling experts in mathematical biology, history of science, psychology, philosophy, and theology, Martin Nowak and Sarah Coakley take an interdisciplinary approach to the terms “cooperation” and “altruism.” Using game theory, the authors elucidate mechanisms by which cooperation—a form of working together in which one individual benefits at the cost of another—arises through natural selection. They then examine altruism—cooperation which includes the sometimes conscious choice to act sacrificially for the collective good—as a key concept in scientific attempts to explain the origins of morality. Discoveries in cooperation go beyond the spread of genes in a population to include the spread of cultural transformations such as languages, ethics, and religious systems of meaning. The authors resist the presumption that theology and evolutionary theory are inevitably at odds. Rather, in rationally presenting a number of theological interpretations of the phenomena of cooperation and altruism, they find evolutionary explanation and theology to be strongly compatible.

Randomness in Evolution

Author : John Tyler Bonner
Publisher : Princeton University Press
ISBN 13 : 1400846420
Total Pages : 149 pages
Book Rating : 4.4/5 (8 download)

DOWNLOAD NOW!

Book Synopsis Randomness in Evolution by : John Tyler Bonner

Download or read book Randomness in Evolution written by John Tyler Bonner and published by Princeton University Press. This book was released on 2013-03-21 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: The important role that randomness plays in evolutionary change John Tyler Bonner, one of our most distinguished and insightful biologists, here challenges a central tenet of evolutionary biology. In this concise, elegantly written book, he makes the bold and provocative claim that some biological diversity may be explained by something other than natural selection. With his customary wit and accessible style, Bonner makes an argument for the underappreciated role that randomness—or chance—plays in evolution. Due to the tremendous and enduring influence of Darwin's natural selection, the importance of randomness has been to some extent overshadowed. Bonner shows how the effects of randomness differ for organisms of different sizes, and how the smaller an organism is, the more likely it is that morphological differences will be random and selection may not be involved to any degree. He traces the increase in size and complexity of organisms over geological time, and looks at the varying significance of randomness at different size levels, from microorganisms to large mammals. Bonner also discusses how sexual cycles vary depending on size and complexity, and how the trend away from randomness in higher forms has even been reversed in some social organisms. Certain to provoke lively discussion, Randomness in Evolution is a book that may fundamentally change our understanding of evolution and the history of life.