Multiple Sclerosis And Related Disorders

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Multiple Sclerosis and Related Disorders

Author : Douglas S. Goodin
Publisher : Elsevier
ISBN 13 : 044463309X
Total Pages : 736 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Multiple Sclerosis and Related Disorders by : Douglas S. Goodin

Download or read book Multiple Sclerosis and Related Disorders written by Douglas S. Goodin and published by Elsevier. This book was released on 2014-02-05 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis. Over the past five years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners. A comprehensive tutorial reference detailing our current foundational understanding of Multiple Sclerosis Includes chapters on key topics including the genetics of MS, MRI imaging and MS, and the latest treatment options Each chapter is translational and focuses on current research and impact on diagnosis and treatment options

Multiple Sclerosis and Related Disorders

Author : Robert J. Fox, MD
Publisher : Springer Publishing Company
ISBN 13 : 0826125948
Total Pages : 441 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Multiple Sclerosis and Related Disorders by : Robert J. Fox, MD

Download or read book Multiple Sclerosis and Related Disorders written by Robert J. Fox, MD and published by Springer Publishing Company. This book was released on 2018-08-28 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revised and updated second edition of Multiple Sclerosis and Related Disorders: Clinical Guide to Diagnosis, Medical Management, and Rehabilitation, the only comprehensive but practical source of core information on multiple sclerosis and other demyelinating disorders. Intended as a ready reference for clinicians who provide ongoing care to MS patients, this book combines evidence-based science with experience-based guidance to present current standards and management protocols from leading MS centers. Beginning with the scientific underpinnings of MS for clinicians, the book proceeds through diagnosis, including initial symptoms, diagnostic criteria and classification, imaging, and differential diagnosis, and onto approved treatments for the various MS types and emerging therapies. Later parts of the book discuss symptom management and rehabilitation with chapters focusing on specific side effects, along with considerations for special populations, comorbidities, societal and family issues, and related autoimmune disorders that are often mistaken for MS. Throughout, chapters include lists of Key Points both for clinicians and for patients and families, and management pearls are boxed for quick reference and clinical utility. Illustrations, tables, algorithms, assessment scales, and up-to-date MRI imaging enrich the text, making this a wide-ranging clinical reference for all members of the MS care team. New to the Second Edition: Includes summary recommendations from new AAN practice guidelines for use of DMTs All chapters updated to reflect the latest literature and diagnostic criteria Five entirely new chapters added to expand coverage of treatment, rehabilitation and symptom management, and special issues related to MS Treatment section has been completely revised to better capture current approaches to disease modifying therapies, with separate chapters devoted to injection and oral therapies, infusion therapies, and treatments for progressive forms of MS Related autoimmune diseases section significantly expanded to include transverse myelitis, autoimmune encephalitis, and neurosarcoidosis

Multiple Sclerosis and Related Disorders

Author : Francois Bethoux, MD
Publisher : Demos Medical Publishing
ISBN 13 : 1617051276
Total Pages : 400 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis Multiple Sclerosis and Related Disorders by : Francois Bethoux, MD

Download or read book Multiple Sclerosis and Related Disorders written by Francois Bethoux, MD and published by Demos Medical Publishing. This book was released on 2013-06-18 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS patients. Information on disease history, pathophysiology, and biology is included to provide clinicians with a framework for understanding current diagnosis, monitoring, and treatment strategies for these disorders. In addition to thoroughly reviewing the newest disease-modifying treatments, the authors have devoted significant focus to the symptoms that frequently manifest and their treatment options. Symptoms and functional limitations are the ìface of the diseaseî for patients, and present their own set of challenges for practitioners. The book proceeds through diagnosis (initial symptoms, criteria and classification, imaging, lab tests, and differential diagnosis), approved treatments for the various MS types including emerging therapies where appropriate, symptom management, rehabilitative issues, general health and wellness, and an overview of MS clinical trials. Special populations, societal and family issues, and related disorders that are often mistaken for MS are also covered. Dedicated chapters on neuromyelitis optica and acute disseminated encephalomyelitis incorporate newer diagnostic criteria. Because comorbidities often make the management of MS-related disability more complex, the book addresses these comorbidities as part of a comprehensive management plan. To enhance the clinical utility, critical-to-know information and management pearls are boxed for quick reference and most chapters include lists of ìKey Pointsî for clinicians, and for patients and families. Illustrations, tables, graphs, assessment scales, and up-to-date MRI imaging inform the text throughout. The treatment chapters include specific recommendations where available and highlight areas of controversy. Illustrative cases go beyond the literature to amplify clinical recommendations and provide real-world guidance for practitioners. Illustrations, tables, graphs, assessment scales, and up-to-date MRI imaging inform the text throughout. Multiple Sclerosis and Related Disorders features: Comprehensive clinical reference for all members of the MS care team Focus on practical approaches to diagnosis, treatment, counseling, and rehabilitative strategies Reviews the latest disease modifying therapies Extensive chapters on symptom management and womenís issues in MS Edited and written primarily by expert clinicians at Cleveland Clinic/Mellen Center Evidence- and experience-based guidance Dedicated chapters on neuromyelitis optica and acute disseminated encephalomyelitis incorporating newer diagnostic criteria Includes treatment guidelines and numerous illustrations, tables, scales; key information is highlighted for quick reference

Multiple Sclerosis and Related Disorders

Author : Alexander Rae-Grant, MD
Publisher : Demos Medical Publishing
ISBN 13 : 1936287757
Total Pages : 344 pages
Book Rating : 4.9/5 (362 download)

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Book Synopsis Multiple Sclerosis and Related Disorders by : Alexander Rae-Grant, MD

Download or read book Multiple Sclerosis and Related Disorders written by Alexander Rae-Grant, MD and published by Demos Medical Publishing. This book was released on 2013-06-18 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book proceeds through diagnosis (initial symptoms, criteria and classification, imaging, lab tests, and differential diagnosis), approved treatments for the various MS types (including emerging therapies where appropriate), symptom management, rehabilitative issues and general health and wellness, considerations for special populations, societal and family issues, CCSVI, related disorders that are often mistaken for MS, and an overview of MS clinical trials. To enhance the clinical utility, “bottom line” information will be pulled out and boxed or bolded for quick reference. Illustrations, tables, graphs, and assessment scales will inform the text throughout. Chapters will open and close with lists of key points where appropriate, and treatment chapters will include specific recommendations where available (AAN guidelines, Cochrane; including levels of evidence to support recommendations) and highlight areas of controversy. Selected chapters will also feature a section on the “Cleveland Clinic approach” to go beyond the literature and provide real-world guidance for practitioners.

Clinical Neuroimmunology

Author : Syed A. Rizvi
Publisher : Springer Science & Business Media
ISBN 13 : 9781603278607
Total Pages : 404 pages
Book Rating : 4.2/5 (786 download)

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Book Synopsis Clinical Neuroimmunology by : Syed A. Rizvi

Download or read book Clinical Neuroimmunology written by Syed A. Rizvi and published by Springer Science & Business Media. This book was released on 2011-09-03 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders serves as an indispensable resource for physicians interested in, and dealing with, this very complex and evolving branch of neurology. This comprehensive title provides an introduction to basic neuroimmunology and principles of immunotherapy and also serves as a thorough guide to immune-mediated disorders of the central and peripheral nervous system, as well as other systemic disorders with a significant neuroimmunologic component. The chapters are written by experts in their fields and include the most up to date scientific information. This volume is made to simplify complex immunological mechanisms and to focus on practical patient-related issues. Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders is an invaluable addition to the literature and will be of significant interest to neurologists, residents and fellows, internists, and general practitioners who treat patients with neurologic disorders and other systemic autoimmune diseases.

Multiple Sclerosis

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309072859
Total Pages : 457 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Multiple Sclerosis by : Institute of Medicine

Download or read book Multiple Sclerosis written by Institute of Medicine and published by National Academies Press. This book was released on 2001-08-10 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

Multiple Sclerosis

Author : Alireza Minagar
Publisher : Academic Press
ISBN 13 : 0128010053
Total Pages : 538 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Multiple Sclerosis by : Alireza Minagar

Download or read book Multiple Sclerosis written by Alireza Minagar and published by Academic Press. This book was released on 2015-11-09 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple Sclerosis: A Mechanistic View provides a unique view of the pathophysiology of multiple sclerosis (MS) and related disorders. As the only book on the market to focus on the mechanisms of MS rather than focusing on the clinical features and treatment of the disease, it describes the role of genetic and environmental factors in the pathogenesis of MS, the role of specific cells in the pathophysiology of the disease, and the pathophysiology of inflammatory and neurodegenerative disorders related to MS. The book provides discussion of neurodegeneration and neuroregeneration, two critical emerging areas of research, as well as detailed discussion of the mechanisms of action of the approved and investigational drugs for treatment of MS and the emerging role of magnetic resonance spectroscopy (MRI) in investigations into MS. It is the only book on the market to offer comprehensive coverage of the known mechanisms of MS and related diseases, and contains contributions from physicians and researchers who are worldwide experts in the field of study. Focuses on the pathophysiologic mechanisms of multiple sclerosis and the mechanisms of action in agents for the treatment of MS Discusses the roles of neurodegeneration and neuroregeneration in MS and related diseases Authored and edited by international leaders in the field of MS research

Demyelinating Disorders of the Central Nervous System in Childhood

Author : Dorothée Chabas
Publisher : Cambridge University Press
ISBN 13 : 1139496514
Total Pages : 297 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Demyelinating Disorders of the Central Nervous System in Childhood by : Dorothée Chabas

Download or read book Demyelinating Disorders of the Central Nervous System in Childhood written by Dorothée Chabas and published by Cambridge University Press. This book was released on 2011-03-17 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although multiple sclerosis and other disorders of myelin formation and repair are most commonly associated with adults, they can also occur in infants, children and adolescents. Up to 5 percent of those with MS experience symptoms before the age of 18, and the number of cases diagnosed is rising. There is a lack of awareness about these diseases in childhood, however, even amongst pediatric neurologists and MS specialists. Demyelinating Disorders of the Central Nervous System in Childhood provides comprehensive coverage of these diseases, highlighting throughout the differences between management in childhood and in adults. With sections dedicated to the diagnosis, course, treatment and biology of pediatric MS, detailed chapters on other childhood demyelinating diseases, including acute disseminated encephomyelitis, optic neuritis, acute complete transverse myelitis and neuromyelitis optica, are also provided. Essential reading for pediatric neurologists and MS specialists, this book will also be valuable reading for adult neurologists and pediatricians.

White Matter Diseases

Author : Massimo Filippi
Publisher : Springer Nature
ISBN 13 : 303038621X
Total Pages : 215 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis White Matter Diseases by : Massimo Filippi

Download or read book White Matter Diseases written by Massimo Filippi and published by Springer Nature. This book was released on 2020-02-13 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides cutting-edge information on the epidemiology, etiopathogenesis, clinical manifestations, diagnostic procedures and treatment approaches for the main white matter (WM) disorders of the central nervous system (CNS). WM lesions are associated with many neurological conditions, and with aging. The diagnostic work-up of neurological diseases characterized by the presence of these lesions has changed dramatically over the past few years. This is mainly due on the one hand to the discovery of specific pathogenetic factors in some of these conditions, and on the order to the optimized use of diagnostic tools. All of this has resulted in new diagnostic algorithms, and in the identification of new neurological conditions. The book offers neurologists essential guidance in the diagnosis and treatment of the most frequent WM conditions, promoting their correct and cost-saving diagnosis and management. By integrating neurological, laboratory and imaging concepts with the demands of accurate diagnosis, this reference guide provides a state-of-the-art overview of the current state of knowledge on these conditions, as well as practical guidelines for their diagnosis and treatment.

Guide for the Care and Use of Laboratory Animals

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309154006
Total Pages : 246 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : National Research Council

Download or read book Guide for the Care and Use of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2011-01-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Multiple Sclerosis As A Neuronal Disease

Author : Stephen Waxman
Publisher : Elsevier
ISBN 13 : 9780080489414
Total Pages : 496 pages
Book Rating : 4.4/5 (894 download)

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Book Synopsis Multiple Sclerosis As A Neuronal Disease by : Stephen Waxman

Download or read book Multiple Sclerosis As A Neuronal Disease written by Stephen Waxman and published by Elsevier. This book was released on 2005-05-27 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the role of neurons in multiple sclerosis (MS) and the changes that occur in neurons as a result of MS. It places MS in a new and important perspective that not only explains the basis for symptom production, remission, and progress in MS, but also promises to open up new therapeutic possibilities. * Brings together the latest information from clinical, pathological, imaging, molecular, and pharmacological realms to explore the neurobiology of Multiple Sclerosis * Places MS in a new and important perspective that promises to open up new therapeutic avenues * Superbly illustrated and referenced

Multiple Sclerosis

Author : Dr. T. Jock Murray, MS
Publisher : Demos Medical Publishing
ISBN 13 : 9781934559277
Total Pages : 264 pages
Book Rating : 4.5/5 (592 download)

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Book Synopsis Multiple Sclerosis by : Dr. T. Jock Murray, MS

Download or read book Multiple Sclerosis written by Dr. T. Jock Murray, MS and published by Demos Medical Publishing. This book was released on 2004-12-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple Sclerosis: The History of a Disease won a 2005 ForeWord Book of the Year Silver Medal! The basic facts about multiple sclerosis are well known: it is the most common neurologic disease of young adults, usually beginning with episodic attacks of neurologic symptoms, then entering a progressive phase some years later. Its onset has an average age of 30, and occurs in about 1 in 500 individuals of European ancestry living primarily in temperate climates. There appears to be a complex interaction between a genetic predisposition and an environmental trigger that initiates the disease. But these facts do not convey the impact of the disease on the people whose lives it affects. In this elegantly written and comprehensive history, we meet individuals who suffered with MS in the centuries before the disease had a name, including blessed Lidwina of Holland, who took joy from her misery, believing that she was sent to accept suffering for the sins of others; Augustus d'Est, grandson of George III and cousin of Queen Victoria, whose case shows how someone with access to the best of medical care of the age was understood and managed; and Heinrich Heine, the great German poet, who also had access to all medical services that were available, but who progressed into his mattress grave in two decades, aware of the loss of physical ability while still able to compose great poetry to the end. From these early cases the author demonstrates how progress in diagnosing and managing multiple sclerosis has paralleled the development of medical science, from the early developments in modern studies of anatomy and pathology, to the framing of the disease in the nineteenth century, and eventually to modern diagnosis and treatment. From beginning to end, Dr. Murray takes us on a fascinating journey of discovery, in the process showing how the evolution of our understanding of multiple sclerosis has been part of the greater history of medical knowledge.

Multiple Sclerosis for the Non-Neurologist

Author : Mary Ann Picone
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975102525
Total Pages : 687 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Multiple Sclerosis for the Non-Neurologist by : Mary Ann Picone

Download or read book Multiple Sclerosis for the Non-Neurologist written by Mary Ann Picone and published by Lippincott Williams & Wilkins. This book was released on 2019-05-07 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent rapid changes in the field of multiple sclerosis management have made the task of staying well-informed a challenge for neurologists, and even more so for other healthcare practitioners who are involved in symptom evaluation and treatment. Multiple Sclerosis for the Non-Neurologist is an up-to-date resource for physicians, residents, fellows, and others who care for patients with MS. It contains authoritative information on all aspects of this complex disease, including monitoring requirements for patients with MS, potential risks and adverse events of disease modifying or symptomatic therapies, and possible drug interactions and contraindications of medications.

Multiple Sclerosis and Related Disorders

Author :
Publisher :
ISBN 13 :
Total Pages : 325 pages
Book Rating : 4.:/5 (969 download)

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Book Synopsis Multiple Sclerosis and Related Disorders by :

Download or read book Multiple Sclerosis and Related Disorders written by and published by . This book was released on 2013 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multiple Sclerosis

Author : Ian S. Zagon
Publisher :
ISBN 13 : 9780994438133
Total Pages : 137 pages
Book Rating : 4.4/5 (381 download)

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Book Synopsis Multiple Sclerosis by : Ian S. Zagon

Download or read book Multiple Sclerosis written by Ian S. Zagon and published by . This book was released on 2017 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Diseases of the Brain, Head and Neck, Spine 2020–2023

Author : Juerg Hodler
Publisher : Springer Nature
ISBN 13 : 303038490X
Total Pages : 252 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Diseases of the Brain, Head and Neck, Spine 2020–2023 by : Juerg Hodler

Download or read book Diseases of the Brain, Head and Neck, Spine 2020–2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Neuroimmune Diseases

Author : Hiroshi Mitoma
Publisher : Springer
ISBN 13 : 3030195155
Total Pages : 822 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Neuroimmune Diseases by : Hiroshi Mitoma

Download or read book Neuroimmune Diseases written by Hiroshi Mitoma and published by Springer. This book was released on 2019-08-13 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt: A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases