Mechanisms of Environmental Mutagenesis-Carcinogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 1461538084
Total Pages : 276 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Mechanisms of Environmental Mutagenesis-Carcinogenesis by : A. Kappas

Download or read book Mechanisms of Environmental Mutagenesis-Carcinogenesis written by A. Kappas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 19th annual meeting of the European Environmental Mutagen Society was held in Rhodes, Greece, from October 21st to 26th, 1989. The programme was chosen to explore what is currently known about the mechanisms of mutagenesis and carcinogenesis, induced by environmental agents, and the questions regarding the relationship of these two processes. Recent findings, techniques and methodologies in the area of biomonitoring of humans exposed to environmental mutagens-carcinogens were presented and considerable attention was also paid to the aspects and issues of collaborative environmental policy. Researchers from allover the world contributed to the programme of the meeting with posters and oral presentations, providing a variety of new data and interesting scientific approaches. A number of outstanding scientists were invited to present the results of their work. It is only their presenta tions which are included in this book, covering the following topics: Mutations and carcinogenesis; mechanisms of chemical ly-induced genetic effects on molecular, chromosomal and cell division level; adaptability and repair mechanisms; chemical carcinogenesis and oncogenes; structure and metabolism of mutagens-carcinogens; biomonitoring and epidemiology of humans exposed to environmental mutagens-carcinogens. For the sake of evaluating and controlling the mutagenic and carcinogenic potential of our environment it is indispens able to understand the mechanisms and processes by which chemicals act on the genetic material, causing either heredi tary disease or cancer. The pUblication of these proceedings will hopefully contribute to this task.

Environmental Mutagenesis, Carcinogenesis, and Plant Biology

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Author :
Publisher : Greenwood
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Environmental Mutagenesis, Carcinogenesis, and Plant Biology by : Edward J. Klekowski

Download or read book Environmental Mutagenesis, Carcinogenesis, and Plant Biology written by Edward J. Klekowski and published by Greenwood. This book was released on 1982 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mechanisms of Carcinogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 9400925263
Total Pages : 210 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Mechanisms of Carcinogenesis by : Elizabeth K. Weisburger

Download or read book Mechanisms of Carcinogenesis written by Elizabeth K. Weisburger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.

Progress in Environmental Mutagenesis

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Publisher : North-Holland
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.:/5 (42 download)

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Book Synopsis Progress in Environmental Mutagenesis by : European Environmental Mutagen Society. Yugoslav Section

Download or read book Progress in Environmental Mutagenesis written by European Environmental Mutagen Society. Yugoslav Section and published by North-Holland. This book was released on 1980 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comparative mutagenesis: chemical versus radiation; Molecular mechanisms of genetic changes; Experimental and epidemiological approach to mutagenesis and carcinogenesis.

MECHANISM OF ENVIRONMENTAL CARCINOGENESIS

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Publisher : CRC-Press
ISBN 13 : 9780849346729
Total Pages : 144 pages
Book Rating : 4.3/5 (467 download)

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Book Synopsis MECHANISM OF ENVIRONMENTAL CARCINOGENESIS by : J. Carl Barrett

Download or read book MECHANISM OF ENVIRONMENTAL CARCINOGENESIS written by J. Carl Barrett and published by CRC-Press. This book was released on 1987-07-31 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Studies on the Mutagenic Mechanisms of the Potent Environmental Carcinogen, Benzo(A)pyrene

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Publisher :
ISBN 13 :
Total Pages : 434 pages
Book Rating : 4.:/5 (329 download)

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Book Synopsis Studies on the Mutagenic Mechanisms of the Potent Environmental Carcinogen, Benzo(A)pyrene by : Henry Rodriguez

Download or read book Studies on the Mutagenic Mechanisms of the Potent Environmental Carcinogen, Benzo(A)pyrene written by Henry Rodriguez and published by . This book was released on 1993 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Progress in Environmental Mutagenesis and Carcinogenesis

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Publisher :
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Progress in Environmental Mutagenesis and Carcinogenesis by : European Environmental Mutagen Society

Download or read book Progress in Environmental Mutagenesis and Carcinogenesis written by European Environmental Mutagen Society and published by . This book was released on 1981 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mutation, Cancer, and Malformation

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Publisher : Springer Science & Business Media
ISBN 13 : 1461323991
Total Pages : 852 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Mutation, Cancer, and Malformation by : Ernest H.Y. Chu

Download or read book Mutation, Cancer, and Malformation written by Ernest H.Y. Chu and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the early 1930s, when I was a graduate student and later a post-doctoral researcher at the National Research Council for the University of Wisconsin at Madison, we had the opportunity to get acquainted with many graduate students from China who were sent to the University for training in modern basic sciences as well as social sciences. The University of Wisconsin continues to graduate a large number of Chinese students. Economic conditions in the 1930s were very precarious for the United States and other parts of the world. Many of us students grew closer together because we were living on similarly tight budgets. As a matter of fact, we subleased a part of our apartment in Madison to some Chinese graduate students. This was a very nice opportunity for us to learn about the scientific and cultural back ground of our Chinese friends. Many of them came from the interior of China and had had very little opportunity to become acquainted with people from a western culture. Living with these students was a very pleasant and educational experience which gave us a good pic ture of the cultural life and educational system of China at that time--an intimate picture that one normally would not see without travelling in that country.

Induced Mutagenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 1468443828
Total Pages : 433 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Induced Mutagenesis by : Christopher W. Lawrence

Download or read book Induced Mutagenesis written by Christopher W. Lawrence and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concern is often expressed that our environment may include an increasingly large variety of mutagens, but the extent of the potential hazard they pose has yet to be fully evaluated. A variety of empirical procedures has been devised with which to estimate the mutagenic potency of suspect agents, and the relative merits of different tests are currently under debate. Although such tests are of great value, and are indeed indispensable, they are not, nevertheless, sufficient. In the long term, accurate estimation of hazard will also require a better understanding of the various mechanisms of mutagenesis, and in many instances these remain remarkably elusive. Our knowledge and appreciation of the problem has increased substantially over the last few years, but the precise way in which many mutagens cause mutations is not yet known. The aims of this conference were therefore two-fold. The first was to survey present information about mutagenic mechanisms, drawing together data from work with various experimental approaches and organisms, in order to discern the principles governing the action of different mutagens. The second was to examine the implications of such principles for the execution and evaluation of test procedures, and critically assess the research areas that need further attention in order to improve the interpretation of test results. Chris Lawrence v ACKNOWLEDGEMENT We gratefully acknowledge the support provided for this Conference by the U.,S. Department of Energy, The Foundation for Microbiology, Exxon Corporation and the University of Rochester.

How Tobacco Smoke Causes Disease

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Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Environmental Mutagenesis

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Publisher : Academic Press
ISBN 13 : 9780122204326
Total Pages : 0 pages
Book Rating : 4.2/5 (43 download)

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Book Synopsis Environmental Mutagenesis by : Consultant Surgeon Robin Phillips, Esq

Download or read book Environmental Mutagenesis written by Consultant Surgeon Robin Phillips, Esq and published by Academic Press. This book was released on 1995-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Germ-line and somatic mutations are recognized as significant causes of human disease, and so the detection, identification and study of mutagens in the environment is of increasing mutagenesis.Environmental Mutagenesis describes our current knowledge of the molecular mechanisms of mutagenesis and assesses the role of mutagens in cancer and inherited disease. Full details are also provided on all the major in vivo and in vitro methods of mutagenecity testing, including recently developed methods such as fluorescence in situ hybridization (FISH), the use of genetically engineered cells, and transgene technology.This book presents a unique overview of the current status of mutagenecity research and genetics toxicology in the form of reviews by leading researchers in the field. It is essential reading for all with an interest in genetic toxicology and molecular carcinogenesis, including molecular geneticists, genetic counselors and clinicians.

Environmental Mutagens and Carcinogens

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Publisher :
ISBN 13 :
Total Pages : 802 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis Environmental Mutagens and Carcinogens by : Takashi Sugimura

Download or read book Environmental Mutagens and Carcinogens written by Takashi Sugimura and published by . This book was released on 1982 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mutagenic Effects of Environmental Contaminants

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Publisher : Elsevier
ISBN 13 : 0323160107
Total Pages : 212 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Mutagenic Effects of Environmental Contaminants by : H.E. Sutton

Download or read book Mutagenic Effects of Environmental Contaminants written by H.E. Sutton and published by Elsevier. This book was released on 2012-12-02 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mutagenic Effects of Environmental Contaminants investigates the mutagenic consequences of environmental contaminants, such as pesticides, industrials, food additives, drugs, and biologicals, as well as the possible relationships between mutagenesis and carcinogenesis. It describes the monitoring of chemical mutagens in the environment and the ways that genetic mutations cause disease in humans. Organized into 14 chapters, this volume begins with an overview of the current burden of human genetic disease and the biochemical mechanisms of mutation. It then discusses practical and feasible methods that use a variety of organisms to screen potential mutagenic agents, increased mutation rates in human populations, mutagens that are currently used commercially, and the interrelationships between mutagenicity, carcinogenicity, and teratogenicity. The reader is also introduced to genetic toxicology, detection of chemically induced mutations in experimental animals, and chromosome and somatic mutations in humans. This book is a valuable resource for scientists, policymakers, and administrators of environmental programs.

Carcinogens, Dna Damage And Cancer Risk: Mechanisms Of Chemical Carcinogenesis

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Publisher : World Scientific
ISBN 13 : 981323721X
Total Pages : 392 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Carcinogens, Dna Damage And Cancer Risk: Mechanisms Of Chemical Carcinogenesis by : Miriam Christine Poirier

Download or read book Carcinogens, Dna Damage And Cancer Risk: Mechanisms Of Chemical Carcinogenesis written by Miriam Christine Poirier and published by World Scientific. This book was released on 2018-09-28 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: As chemical exposures and cancer rates increase worldwide, there is a need for students, researchers, public health professionals, and physicians to understand the mechanisms connecting exposure with human cancer risk. This new book is an essential reference, as well as introduction to the field of chemical carcinogenesis, with particular focus on DNA damage as a critical link between exposure and disease, and emphasis on biomarkers associated with cancer risk in humans. In addition to DNA damage, related topics covered include metabolism of selected chemical carcinogens, exposure-induced epigenetic changes, cancer-associated mutations and reduction of DNA damage and cancer risk by chemoprevention. The book is designed to be a comprehensive guide to basic principles, a teaching tool for academics, and a map for the development of protective mechanisms to reduce human cancer risk.

Mutation and the Environment

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Publisher :
ISBN 13 :
Total Pages : 432 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Mutation and the Environment by :

Download or read book Mutation and the Environment written by and published by . This book was released on 1990 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mutation and the Environment: Basic mechanisms

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (9 download)

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Book Synopsis Mutation and the Environment: Basic mechanisms by :

Download or read book Mutation and the Environment: Basic mechanisms written by and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mechanisms of Environmental Carcinogenesis: Role of genetic and epigenetic changes

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Author :
Publisher :
ISBN 13 :
Total Pages : 168 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Mechanisms of Environmental Carcinogenesis: Role of genetic and epigenetic changes by :

Download or read book Mechanisms of Environmental Carcinogenesis: Role of genetic and epigenetic changes written by and published by . This book was released on 1987 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: