Macrocyclic Polyamines

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Macrocyclic Polyamines

Author : Xiaoqi Yu
Publisher : John Wiley & Sons
ISBN 13 : 3527341870
Total Pages : 226 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Macrocyclic Polyamines by : Xiaoqi Yu

Download or read book Macrocyclic Polyamines written by Xiaoqi Yu and published by John Wiley & Sons. This book was released on 2018-02-20 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive book focusing on synthesis and applications of macrocyclic polyamines and their derivatives Macrocyclic polyamines are a class of widely used important compounds. This is the first book that systematically summarizes the synthesis and applications of macrocyclic polyamines and their analogues, including the properties and synthetic methods of macrocyclic polyamines, chemical nucleases based on macrocyclic polyamines, the derivatives of macrocyclic polyamines as nano-vector materials, macrocyclic polyamines derivatives for bio-imaging, chemical sensors based on macrocyclic polyamines, and other applications of macrocyclic polyamines. Macrocyclic Polyamines: Synthesis and Applications includes most of the studies involving macrocyclic polyamines and their derivatives, and may be used as a reference for the researchers in related fields. It offers in-depth coverage of cyclization modes; special procedures for tetraza macrocyclic compounds; diacids-diamines condensation; oxidative DNA cleaving by macrocyclic polyamines; lipids with cationic MPA headgroups; the derivatives of DOTA, DO3A, and PCTA; receptors for anions; sensors for bioactive molecules; macrocyclic polyamines for solvent extraction and membrane transport of amino acids and their derivatives, electrophoretic separation, and open-tubular CEC; and much more. ?The first book that systematically summarizes the chemistry of macrocyclic polyamines and their derivatives in terms of synthetic methods for their preparation, functionalization, and application in the main fields of chemical sensors, chemical nucleases, drug-delivery, bio-imaging and vector materials ?Provides a comprehensive reference for the researchers working on macrocyclic polyamines ?Offers train of thought in related research fields such as organic chemistry, coordination chemistry, analytical chemistry, supramolecular chemistry, biomaterials, etc. Macrocyclic Polyamines: Synthesis and Applications will not only provide a reference for the researchers working on macrocyclic polyamines, but also offer opportunities for researchers in related research fields to understand the benefits of these key compounds.

The Physiology of Polyamines, Volume I

Author : Uriel Bachrach
Publisher : CRC Press
ISBN 13 : 1000446379
Total Pages : 394 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis The Physiology of Polyamines, Volume I by : Uriel Bachrach

Download or read book The Physiology of Polyamines, Volume I written by Uriel Bachrach and published by CRC Press. This book was released on 2021-05-30 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of polyamines is presented in this useful, two-volume publication. Basic information describing the role of polyamines in the processes of growth and differentiation is given. Also included are data on the regulation of polyamine biosynthesis and metabolism and their interactions with nucleic acids. Several chapters are devoted to the role of polyamines in various aspects of plant biology, with a special emphasis on their participation in the response of plants to extreme environments. Special attention is given to the use of inhibitors of polyamine biosynthesis as potential antitumor and antiproliferative agents. Additionally, progress in the molecular biology and genetic engineering of genes coding for polyamine biosynthetic enzymes is described. Cancer researchers, biologists, geneticists, biochemists, physiologists, and clinicians will find this volume indispensable.

Antioxidants in Disease Mechanisms and Therapy

Author :
Publisher : Academic Press
ISBN 13 : 0080581307
Total Pages : 734 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Antioxidants in Disease Mechanisms and Therapy by :

Download or read book Antioxidants in Disease Mechanisms and Therapy written by and published by Academic Press. This book was released on 1996-12-10 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antioxidants in Disease Mechanisms and Therapy presents molecular actions of natural and synthetic antioxidants and emphasizes the potential role in disease mechanisms and therapeutic strategies. The modulationof gene expression by the induction of antioxidant enzymes is a novel role beyond the direct antioxidant action. The volume explores the current state of knowledge on oxidants and antioxidants in disease processes, including arteriosclerosis, adult respiratory distress syndrome, cystic fibrosis, Down's syndrome, inflammation, cataract, age-related macular degeneration, afflications of the nervous system, AIDS, liver diseases, diabetes, skin diseases, and cancer. Contains cutting-edge information on focused topics written by expert scientists Provides the first in-depth treatment of novel compounds, such as melatonin and polyamines Attempts molecular pathophysiology which links basic science and the clinic Presents critical assessment of controversial topics

Macrocyclic and Supramolecular Chemistry

Author : Reed M. Izatt
Publisher : John Wiley & Sons
ISBN 13 : 1119053870
Total Pages : 504 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Macrocyclic and Supramolecular Chemistry by : Reed M. Izatt

Download or read book Macrocyclic and Supramolecular Chemistry written by Reed M. Izatt and published by John Wiley & Sons. This book was released on 2016-05-31 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book commemorates the 25th anniversary of the International Izatt-Christensen Award in Macrocyclic and Supramolecular Chemistry. The award, one of the most prestigious of small awards in chemistry, recognizes excellence in the developing field of macrocyclic and supramolecular chemistry Macrocyclic and Supramolecular Chemistry: How Izatt-Christensen Award Winners Shaped the Field features chapters written by the award recipients who provide unique perspectives on the spectacular growth in these expanding and vibrant fields of chemistry over the past half century, and on the role of these awardees in shaping this growth. During this time there has been an upsurge of interest in the design, synthesis and characterization of increasingly more complex macrocyclic ligands and in the application of this knowledge to understanding molecular recognition processes in host-guest chemistry in ways that were scarcely envisioned decades earlier. In October 2016, Professor Jean-Pierre Sauvage and Sir J. Fraser Stoddart (author for chapter 22 "Contractile and Extensile Molecular Systems: Towards Molecular Muscles" by Jean -Pierre Sauvage, Vincent Duplan, and Frédéric Niess and 20 "Serendipity" by Paul R. McGonigal and J. Fraser Stoddart respectively) were awarded the Nobel Prize in Chemistry alongside fellow Wiley author Bernard Feringa, for the design and synthesis of molecular machines.

Polyamines in Biomedical Research

Author : Joseph M. Gaugas
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 500 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Polyamines in Biomedical Research by : Joseph M. Gaugas

Download or read book Polyamines in Biomedical Research written by Joseph M. Gaugas and published by John Wiley & Sons. This book was released on 1980 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tetraazacyclotetradecane Species as Models of the Polyazacrown Macrocycles

Author : Ryszard B. Nazarski
Publisher :
ISBN 13 : 9781616684877
Total Pages : 0 pages
Book Rating : 4.6/5 (848 download)

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Book Synopsis Tetraazacyclotetradecane Species as Models of the Polyazacrown Macrocycles by : Ryszard B. Nazarski

Download or read book Tetraazacyclotetradecane Species as Models of the Polyazacrown Macrocycles written by Ryszard B. Nazarski and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three aliphatic molecules and their subsequently formed protonated congeners are considered as representatives of the macrocyclic polyamines (azacrowns) and related polyammonium salts. Important methodological aspects of structural investigations on these highly mobile aza-substituted macrorings are taken into account, especially concerning aqueous solutions over a whole pH range. This book examines various issues about ascertaining donating sites and sequences of the protonation, dynamics and conformational preferences of such multidentate polyamino ligands as potential chelators (complexones) are considered.

Polyamine Cell Signaling

Author : Jian-Ying Wang
Publisher : Springer Science & Business Media
ISBN 13 : 1597451452
Total Pages : 490 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Polyamine Cell Signaling by : Jian-Ying Wang

Download or read book Polyamine Cell Signaling written by Jian-Ying Wang and published by Springer Science & Business Media. This book was released on 2007-11-19 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyamines are organic cations found in all eukaryotic cells and intimately involved in, and required for, distinct biological functions. An increasing body of evidence indicates that the regulation of cellular polyamines is a central convergence point for the multiple signaling pathways driving various cellular functions. Over the last decade, considerable progress has been made in und- standing the molecular functions of cellular polyamines. These significant findings provide a fundamental basis to not only define the exact role of polyamines in physiology, but also to develop new therapeutic approaches for cancers and other diseases. The major objective of this book is to provide a timely and long lasting guide for investigators in the fields of polyamines, physiology, pharmacology, and cancer research. It will provide a foundation based on research and address the potential for subsequent applications in clinical practice. Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research is divided into four main parts: Part I: Polyamines in Signal Transduction of Cell Proliferation Part II: Polyamines in Cellular Signaling of Apoptosis, Carcinogenesis, and Cancer Therapy Part III: Polyamines in Cell Motility and Cell–Cell Interactions Part IV: Polyamine Homeostasis and Transport This book not only covers the current state-of-the-art findings relevant to cellular and molecular functions of polyamines, but also provides the underlying conceptual basis and knowledge regarding potential therapeutic targeting of polyamines and polyamine metabolism. These points are addressed by int- nationally recognized experts in their contributions to this book.

United States-Japan Seminar on Host-Guest Chemistry

Author : George W. Gokel
Publisher : Springer Science & Business Media
ISBN 13 : 9400909691
Total Pages : 276 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis United States-Japan Seminar on Host-Guest Chemistry by : George W. Gokel

Download or read book United States-Japan Seminar on Host-Guest Chemistry written by George W. Gokel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Aza-Crown Macrocycles

Author : Jerald S. Bradshaw
Publisher : John Wiley & Sons
ISBN 13 : 0470188901
Total Pages : 896 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Aza-Crown Macrocycles by : Jerald S. Bradshaw

Download or read book Aza-Crown Macrocycles written by Jerald S. Bradshaw and published by John Wiley & Sons. This book was released on 2009-09-17 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Polyamine Drug Discovery

Author : Patrick M. Woster
Publisher : Royal Society of Chemistry
ISBN 13 : 184973190X
Total Pages : 303 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Polyamine Drug Discovery by : Patrick M. Woster

Download or read book Polyamine Drug Discovery written by Patrick M. Woster and published by Royal Society of Chemistry. This book was released on 2012 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive description of the discovery and therapeutic potential of polyamine drugs.

Supramolecular Chemistry - Fundamentals and Applications

Author : Katsuhiko Ariga
Publisher : Springer Science & Business Media
ISBN 13 : 3540261850
Total Pages : 215 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Supramolecular Chemistry - Fundamentals and Applications by : Katsuhiko Ariga

Download or read book Supramolecular Chemistry - Fundamentals and Applications written by Katsuhiko Ariga and published by Springer Science & Business Media. This book was released on 2006-08-02 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamentals of "supramolecular chemistry" to the latest developments on the subject are covered by this book. It sets out to explain the topic in a relatively easy way. The basic concepts of molecular recognition chemistry are included. Molecules with fascinating shapes and functions such as fullerenes, carbon nanotubes, dendrimers, rotaxane, and catenane, and molecular assemblies are also explained. Thereafter applications of supermolecules to nanotechnology are introduced with many examples of molecular devices. The last part of the book describes biological supermolecules and their mimics. Though simply explained undergraduate and graduate students in Chemistry will be able to use aspects of this work as an advanced textbook.

Small Molecule DNA and RNA Binders

Author : Martine Demeunynck
Publisher : John Wiley & Sons
ISBN 13 : 3527605665
Total Pages : 754 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Small Molecule DNA and RNA Binders by : Martine Demeunynck

Download or read book Small Molecule DNA and RNA Binders written by Martine Demeunynck and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of molecules that selectively bind to nucleic acids has provided many details about DNA and RNA recognition. The range of such substances, such as metal complexes, peptides, oligonucleotides and a wide array of synthetic organic compounds, is as manifold as the functions of nucleic acids. Nucleic acid recognition sequences are often found in the major or minor groove of a double strand, while other typical interactions include intercalation between base pairs or the formation of triple or quadruple helices. One example of a binding mode that has recently been proposed is end stacking on such complex structures as the telomere tetraplex. In this comprehensive book, internationally recognized experts describe in detail the important aspects of nucleic acid binding, and in so doing present impressive approaches to drug design. Since typical substances may be created naturally or synthetically, emphasis is placed on natural products, chemical synthesis, the use of combinatorial libraries, and structural characterization. The whole is rounded off by contributions on molecular modeling, as well as investigations into the way in which any given drug interacts with its nucleic acid recognition site.

A Guide to the Polyamines

Author : Seymour Stanley Cohen
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 632 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis A Guide to the Polyamines by : Seymour Stanley Cohen

Download or read book A Guide to the Polyamines written by Seymour Stanley Cohen and published by Oxford University Press, USA. This book was released on 1998 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: The polyamines are ubiquitous and essential organic cations in prokaryotic and eukaryotic cells. This book is a comprehensive survey of the development of knowledge of their physiological and structural roles. Currently, the genetic and regulatory determinants of the amines and their cellular composition are being explored actively as parameters of normal physiology and aberrant pathologies. Cancer, virus infection, and protozoan parasitism are major examples of the later groups. Studies of the control of polyamine metabolism are providing important therapeutic leads. Further, the structural roles of the amines are being determined at molecular levels, contributing to the understanding of polynucleotide and protein organization and interaction, as well as to the solution of problems of genome transfer. These subjects describe a burgeoning biochemical area involving compounds whose roles in cytoplasmic and nuclear function include numerous aspects of organelle structure, polymer synthesis, and interactions.

The Physiology of Polyamines

Author : Uriel Bachrach
Publisher : CRC Press
ISBN 13 : 9780849368080
Total Pages : 394 pages
Book Rating : 4.3/5 (68 download)

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Book Synopsis The Physiology of Polyamines by : Uriel Bachrach

Download or read book The Physiology of Polyamines written by Uriel Bachrach and published by CRC Press. This book was released on 1989-03-31 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: The area of polyamines is presented in this useful, two-volume publication. Basic information describing the role of polyamines in the processes of growth and differentiation is given. Also included are data on the regulation of polyamine biosynthesis and metabolism and their interactions with nucleic acids. Several chapters are devoted to the role of polyamines in various aspects of plant biology, with a special emphasis on their participation in the response of plants to extreme environments. Special attention is given to the use of inhibitors of polyamine biosynthesis as potential antitumor and antiproliferative agents. Additionally, progress in the molecular biology and genetic engineering of genes coding for polyamine biosynthetic enzymes is described. Cancer researchers, biologists, geneticists, biochemists, physiologists, and clinicians will find this volume indispensable.

Amines—Advances in Research and Application: 2012 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 146499739X
Total Pages : 223 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Amines—Advances in Research and Application: 2012 Edition by :

Download or read book Amines—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amines—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Amines. The editors have built Amines—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Amines in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Amines—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Introduction to the Polyamines

Author : Seymour Stanley Cohen
Publisher : Prentice Hall
ISBN 13 :
Total Pages : 196 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Introduction to the Polyamines by : Seymour Stanley Cohen

Download or read book Introduction to the Polyamines written by Seymour Stanley Cohen and published by Prentice Hall. This book was released on 1971 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Crown Ethers and Analogous Compounds

Author : M. Hiraoka
Publisher : Elsevier
ISBN 13 : 1483290875
Total Pages : 500 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Crown Ethers and Analogous Compounds by : M. Hiraoka

Download or read book Crown Ethers and Analogous Compounds written by M. Hiraoka and published by Elsevier. This book was released on 2016-05-04 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of crown ethers by Pedersen in 1967, several thousands of crown ethers and analogous compounds have been synthesized. Their specific characteristics have been investigated and a variety of applications developed. These developments have led to new fields of chemistry called host-guest chemistry and supramolecular chemistry. This book presents the state-of-the-art of the chemistry of crown ethers and analogous compounds. The first chapter provides an orientation in the new fields of chemistry. Chapter 2 reviews advances in synthetic procedures for crown ethers and analogous compounds including azacrown ethers, thiacrown ethers, functionalized crown ethers, cryptands and others. The focus of chapter 3 is on the concept and synthetic strategies for the molecular design of new crown compounds. Chapters 4-7 are concerned with noteworthy topics in the applications of crown compounds. Chapter 4 deals with the application to ion-selective electrodes and liquid chromatography, both of which are the most important targets in the analytical application of crown compounds. One major application of crown ethers is the design and syntheses of artificial molecules which can catalyze a useful synthetic reaction in an enzyme-mimetic reaction manner, through novel non-covalent complexes. The strategies for enzymatic modelling with crown ethers are covered in chapter 5, while chapter 6 presents the principle of amine-selective colour complexation and its application. In chapter 7 switched-on crown ethers that can respond to environmental stimuli are reviewed. The final chapter is devoted to a wide-ranging discussion of developments in macrocyclic polyamine chemistry. Unlike crown ethers, macrocyclic polyamines, bearing nitrogen donor atoms which belong to a soft base, form complexes with ions of transition metals and heavy metals which are classified as soft acids. Therefore, macrocyclic polyamines are expected to have very versatile applications. Scientists in chemistry, biochemistry, physical organic chemistry, pharmaceutical chemistry and industrial chemistry will find this book a helpful summary and a stimulating contribution to research in this specialized field of crown compounds.