Polyamine Cell Signaling

Download Polyamine Cell Signaling full books in PDF, epub, and Kindle. Read online Polyamine Cell Signaling ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Polyamine Cell Signaling

Author : Jian-Ying Wang
Publisher : Springer Science & Business Media
ISBN 13 : 1597451452
Total Pages : 490 pages
Book Rating : 4.5/5 (974 download)

DOWNLOAD NOW!

Book Synopsis Polyamine Cell Signaling by : Jian-Ying Wang

Download or read book Polyamine Cell Signaling written by Jian-Ying Wang and published by Springer Science & Business Media. This book was released on 2007-11-19 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyamines are organic cations found in all eukaryotic cells and intimately involved in, and required for, distinct biological functions. An increasing body of evidence indicates that the regulation of cellular polyamines is a central convergence point for the multiple signaling pathways driving various cellular functions. Over the last decade, considerable progress has been made in und- standing the molecular functions of cellular polyamines. These significant findings provide a fundamental basis to not only define the exact role of polyamines in physiology, but also to develop new therapeutic approaches for cancers and other diseases. The major objective of this book is to provide a timely and long lasting guide for investigators in the fields of polyamines, physiology, pharmacology, and cancer research. It will provide a foundation based on research and address the potential for subsequent applications in clinical practice. Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research is divided into four main parts: Part I: Polyamines in Signal Transduction of Cell Proliferation Part II: Polyamines in Cellular Signaling of Apoptosis, Carcinogenesis, and Cancer Therapy Part III: Polyamines in Cell Motility and Cell–Cell Interactions Part IV: Polyamine Homeostasis and Transport This book not only covers the current state-of-the-art findings relevant to cellular and molecular functions of polyamines, but also provides the underlying conceptual basis and knowledge regarding potential therapeutic targeting of polyamines and polyamine metabolism. These points are addressed by int- nationally recognized experts in their contributions to this book.

Polyamines

Author : Tomonobu Kusano
Publisher : Springer
ISBN 13 : 443155212X
Total Pages : 336 pages
Book Rating : 4.4/5 (315 download)

DOWNLOAD NOW!

Book Synopsis Polyamines by : Tomonobu Kusano

Download or read book Polyamines written by Tomonobu Kusano and published by Springer. This book was released on 2015-01-07 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers key topics in polyamine research from a range of organisms, including plants, mammals, and prokaryotes such as bacteria and archaea. The book provides an introduction to general concepts in the field of polyamine research, as well as more detailed information. With the availability of genome sequence data from a broad range of organisms, the evolution of the genes involved in polyamine metabolism is discussed. The mode of action of polyamines has been shown to be dependent on cation channels, and this mechanism is described in the book. The origin of polyamine transporters (from bacteria, yeasts, and plants) is described. The various effects of polyamines on growth and survival are also documented. The book details the mechanisms of polyamine homeostasis and the role of polyamine molecules as precursors of secondary metabolites such as plant alkaloids and toxins derived from spiders and wasps. The role of polyamines in longevity and disease is discussed. A link between polyamine contents and cancer progression is reported, as is the use of polyamine metabolites as diagnostic markers in the initial stages of cancer. Moreover, a novel approach that utilizes the polyamine pathway of a parasite as a drug target in African sleeping sickness is described. Therefore, this book is a valuable resource, both as a textbook for undergraduate and graduate students and also as a reference book for front-line polyamine researchers.

Polyamine Metabolism in Disease and Polyamine-Targeted Therapies

Author : Tracy Murray-Stewart
Publisher : MDPI
ISBN 13 : 3039211528
Total Pages : 240 pages
Book Rating : 4.0/5 (392 download)

DOWNLOAD NOW!

Book Synopsis Polyamine Metabolism in Disease and Polyamine-Targeted Therapies by : Tracy Murray-Stewart

Download or read book Polyamine Metabolism in Disease and Polyamine-Targeted Therapies written by Tracy Murray-Stewart and published by MDPI. This book was released on 2019-10-01 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyamines are ubiquitous polycations essential for all cellular life. The most common polyamines in eukaryotes, spermine, spermidine, and putrescine, exist in millimolar intracellular concentrations that are tightly regulated through biosynthesis, catabolism, and transport. Polyamines interact with, and regulate, negatively charged macromolecules, including nucleic acids, proteins, and ion channels. Accordingly, alterations in polyamine metabolism affect cellular proliferation and survival through changes in gene expression and transcription, translation, autophagy, oxidative stress, and apoptosis. Dysregulation of these multifaceted polyamine functions contribute to multiple disease processes, thus their metabolism and function have been targeted for preventive or therapeutic intervention. The correlation between elevated polyamine levels and cancer is well established, and ornithine decarboxylase, the rate-limiting biosynthetic enzyme in the production of putrescine, is a bona fide transcriptional target of the Myc oncogene. Furthermore, induced polyamine catabolism contributes to carcinogenesis that is associated with certain forms of chronic infection and/or inflammation through the production of reactive oxygen species. These and other characteristics specific to cancer cells have led to the development of polyamine-based agents and inhibitors aimed at exploiting the polyamine metabolic pathway for chemotherapeutic and chemopreventive benefit. In addition to cancer, polyamines are involved in the pathologies of neurodegenerative diseases including Alzheimer’s and Parkinson’s, parasitic and infectious diseases, wound healing, ischemia/reperfusion injuries, and certain age-related conditions, as polyamines are known to decrease with age. As in cancer, polyamine-based therapies for these conditions are an area of active investigation. With recent advances in immunotherapy, interest has increased regarding polyamine-associated modulation of immune responses, as well as potential immunoregulation of polyamine metabolism, the results of which could have relevance to multiple disease processes. The goal of this Special Issue of Medical Sciences is to present the most recent advances in polyamine research as it relates to health, disease, and/or therapy.

A Guide to the Polyamines

Author : Seymour Stanley Cohen
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 632 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis A Guide to the Polyamines by : Seymour Stanley Cohen

Download or read book A Guide to the Polyamines written by Seymour Stanley Cohen and published by Oxford University Press, USA. This book was released on 1998 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: The polyamines are ubiquitous and essential organic cations in prokaryotic and eukaryotic cells. This book is a comprehensive survey of the development of knowledge of their physiological and structural roles. Currently, the genetic and regulatory determinants of the amines and their cellular composition are being explored actively as parameters of normal physiology and aberrant pathologies. Cancer, virus infection, and protozoan parasitism are major examples of the later groups. Studies of the control of polyamine metabolism are providing important therapeutic leads. Further, the structural roles of the amines are being determined at molecular levels, contributing to the understanding of polynucleotide and protein organization and interaction, as well as to the solution of problems of genome transfer. These subjects describe a burgeoning biochemical area involving compounds whose roles in cytoplasmic and nuclear function include numerous aspects of organelle structure, polymer synthesis, and interactions.

Polyamine Protocols

Author : David M. L. Morgan
Publisher : Springer Science & Business Media
ISBN 13 : 1592595650
Total Pages : 173 pages
Book Rating : 4.5/5 (925 download)

DOWNLOAD NOW!

Book Synopsis Polyamine Protocols by : David M. L. Morgan

Download or read book Polyamine Protocols written by David M. L. Morgan and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique collection of hands-on enzyme assay techniques to study polyamines and their function. The techniques range from assay methods for enzymes of polyamine biosynthesis and catabolism to measurements of polyamines, polyamine transport, and polyamine effects on cell growth. The methods are presented by leading researchers who have perfected them to a high art, and include clear, step-by-step instructions with numerous hints and tips to ensure readily reproducible results.

Regulation of Gastrointestinal Mucosal Growth

Author : Rao N. Jaladanki
Publisher : Biota Publishing
ISBN 13 : 1615047352
Total Pages : 150 pages
Book Rating : 4.6/5 (15 download)

DOWNLOAD NOW!

Book Synopsis Regulation of Gastrointestinal Mucosal Growth by : Rao N. Jaladanki

Download or read book Regulation of Gastrointestinal Mucosal Growth written by Rao N. Jaladanki and published by Biota Publishing. This book was released on 2016-11-30 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian gastrointestinal mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is preserved through the strict regulation of epithelial cell proliferation, growth arrest, and apoptosis. The control of the growth of gastrointestinal mucosa is unique and, compared with most other tissue in the body, complex. Mucosal growth is regulated by the same hormones that alter metabolism in other tissues, but the gastrointestinal mucosa also responds to host events triggered by the ingestion and presence of food within the digestive tract. These gut hormones and peptides regulate the growth of the exocrine pancreas, gallbladder epithelium, and the mucosa of the oxyntic gland region of the stomach and the small and large intestines. Luminal factors, including nutrients or other dietary factors, secretions, and microbes that occur within the lumen and distribute over a proximal-to-distal gradient, are also crucial for maintenance of normal gut mucosal regeneration and could explain the villous-height-crypt-depth gradient and variety of adaptation, since these factors are diluted, absorbed, and destroyed as they pass down the digestive tract. Recently, intestinal stem cells, cellular polyamines, and noncoding RNAs are shown to play an important role in the regulation of gastrointestinal mucosal growth under physiological and various pathological conditions. In this book, we highlight key issues and factors that control gastrointestinal mucosal growth and homeostasis, with special emphasis on the mechanisms through which epithelial renewal and apoptosis are regulated at the cellular and molecular levels.

Protective Chemical Agents in the Amelioration of Plant Abiotic Stress

Author : Aryadeep Roychoudhury
Publisher : John Wiley & Sons
ISBN 13 : 111955165X
Total Pages : 704 pages
Book Rating : 4.1/5 (195 download)

DOWNLOAD NOW!

Book Synopsis Protective Chemical Agents in the Amelioration of Plant Abiotic Stress by : Aryadeep Roychoudhury

Download or read book Protective Chemical Agents in the Amelioration of Plant Abiotic Stress written by Aryadeep Roychoudhury and published by John Wiley & Sons. This book was released on 2020-05-20 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the chemical agents that protect plants from various environmental stressors Protective Chemical Agents in the Amelioration of Plant Abiotic Stress offers a guide to the diverse chemical agents that have the potential to mitigate different forms of abiotic stresses in plants. Edited by two experts on the topic, the book explores the role of novel chemicals and shows how using such unique chemical agents can tackle the oxidative damages caused by environmental stresses. Exogenous application of different chemical agents or chemical priming of seeds presents opportunities for crop stress management. The use of chemical compounds as protective agents has been found to improve plant tolerance significantly in various crop and non-crop species against a range of different individually applied abiotic stresses by regulating the endogenous levels of the protective agents within plants. This important book: Explores the efficacy of various chemical agents to eliminate abiotic stress Offers a groundbreaking look at the topic and reviews the most recent advances in the field Includes information from noted authorities on the subject Promises to benefit agriculture under stress conditions at the ground level Written for researchers, academicians, and scientists, Protective Chemical Agents in the Amelioration of Plant Abiotic Stress details the wide range of protective chemical agents, their applications, and their intricate biochemical and molecular mechanism of action within the plant systems during adverse situations.

Senescence Signalling and Control in Plants

Author : Maryam Sarwat
Publisher : Academic Press
ISBN 13 : 0128131888
Total Pages : 322 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!

Book Synopsis Senescence Signalling and Control in Plants by : Maryam Sarwat

Download or read book Senescence Signalling and Control in Plants written by Maryam Sarwat and published by Academic Press. This book was released on 2018-11-29 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Senescence Signalling and Control in Plants discusses the studies showing the importance of hormone action on developmental senescence. It shows the involvement of various signaling components (such as EIN2, LOX2) and transcription factors (such as oresara1 or ORE1) in controlling hormonal activity during senescence. Further, the involvement of various micro RNAs (miR164, miR319) in regulating leaf senescence are discussed. Through this book, the authors throw light on all the reverse and forward genetic approaches to reveal the role of various other phytohormones regulating plant senescence and the molecular mechanisms involved. Chapters on relevant topics are contributed by experts working in the area, making this a comprehensive treatise designed to provide an in-depth analysis on the subject matter. Throws light on the involvement of hormones (other than the well- known hormones cytokine and ethylene) in plant senescence Shows the underlying mechanisms on the hormonal actions during senescence Exhibits the involvement of microRNAs during this important plant developmental process

The Genus Yersinia:

Author : Robert D. Perry
Publisher : Springer Science & Business Media
ISBN 13 : 0387721231
Total Pages : 454 pages
Book Rating : 4.3/5 (877 download)

DOWNLOAD NOW!

Book Synopsis The Genus Yersinia: by : Robert D. Perry

Download or read book The Genus Yersinia: written by Robert D. Perry and published by Springer Science & Business Media. This book was released on 2007-09-25 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 9th International Symposium on Yersinia was held in Lexington, Kentucky, USA on October 10-14, 2006. Over 250 Yersinia researchers from 18 countries gathered to present and discuss their research. In addition to 37 oral presentations, there were 150 poster presentations. This Symposium volume is based on selected presentations from the meeting and contains both reviews and research articles. It is divided into six topic areas: 1) genomics; 2) structure and metabolism; 3) regulatory mechanisms; 4) pathogenesis and host interactions; 5) molecular epidemiology and detection; and 6) vaccine and antimicrobial therapy development. Consequently, this volume covers a wide range of current research areas in the Yersinia field.

Biology of the NMDA Receptor

Author : Antonius M. VanDongen
Publisher : CRC Press
ISBN 13 : 9781420044157
Total Pages : 350 pages
Book Rating : 4.0/5 (441 download)

DOWNLOAD NOW!

Book Synopsis Biology of the NMDA Receptor by : Antonius M. VanDongen

Download or read book Biology of the NMDA Receptor written by Antonius M. VanDongen and published by CRC Press. This book was released on 2008-10-29 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written by one of the world’s leading authorities on NMDA receptors, Biology of the NMDA Receptor brings together virtually all the players in this important field.

Polyamines

Author : Anthony E. Pegg
Publisher : Humana Press
ISBN 13 : 9781493958399
Total Pages : 523 pages
Book Rating : 4.9/5 (583 download)

DOWNLOAD NOW!

Book Synopsis Polyamines by : Anthony E. Pegg

Download or read book Polyamines written by Anthony E. Pegg and published by Humana Press. This book was released on 2016-08-23 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, important new findings in the polyamine field and a variety of new experimental systems have revolutionized the study of these ubiquitous cellular components, essential for normal growth and development. In Polyamines: Methods and Protocols, leading researchers contribute an extensive collection of up-to-date laboratory techniques for the further pursuit of polyamine study. The volume delves into vital subjects such as neoplasia studies with animal models and human patients, therapeutic roles for polyamine inhibitors and analogs, polyamine metabolism and oxidative damage, polyamines as regulators of critical ion channels, as well as polyamine transport systems and polyamine-responsive genes. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Polyamines: Methods and Protocols provides a key resource for all scientists pursuing the study of this dynamic and significant aspect of cellular biology.

Annual Plant Reviews, The Plant Hormone Ethylene

Author : Michael T. McManus
Publisher : John Wiley & Sons
ISBN 13 : 1444330039
Total Pages : 433 pages
Book Rating : 4.4/5 (443 download)

DOWNLOAD NOW!

Book Synopsis Annual Plant Reviews, The Plant Hormone Ethylene by : Michael T. McManus

Download or read book Annual Plant Reviews, The Plant Hormone Ethylene written by Michael T. McManus and published by John Wiley & Sons. This book was released on 2012-04-23 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: The plant hormone ethylene is one of the most important, being one of the first chemicals to be determined as a naturally-occurring growth regulator and influencer of plant development. It was also the first hormone for which significant evidence was found for the presence of receptors. This important new volume in Annual Plant Reviews is broadly divided into three parts. The first part covers the biosynthesis of ethylene and includes chapters on S-adenosylmethionine and the formation and fate of ACC in plant cells. The second part of the volume covers ethylene signaling, including the perception of ethylene by plant cells, CTR proteins, MAP kinases and EIN2 / EIN3. The final part covers the control by ethylene of cell function and development, including seed development, germination, plant growth, cell separation, fruit ripening, senescent processes, and plant-pathogen interactions. The Plant Hormone Ethylene is an extremely valuable addition to Wiley-Blackwell's Annual Plant Reviews. With contributions from many of the world's leading researchers in ethylene, and edited by Professor Michael McManus of Massey University, this volume will be of great use and interest to a wide range of plant scientists, biochemists and chemists. All universities and research establishments where plant sciences, biochemistry, chemistry, life sciences and agriculture are studied and taught should have access to this important volume.

Reactive Oxygen, Nitrogen and Sulfur Species in Plants

Author : Mirza Hasanuzzaman
Publisher : John Wiley & Sons
ISBN 13 : 1119468663
Total Pages : 1024 pages
Book Rating : 4.1/5 (194 download)

DOWNLOAD NOW!

Book Synopsis Reactive Oxygen, Nitrogen and Sulfur Species in Plants by : Mirza Hasanuzzaman

Download or read book Reactive Oxygen, Nitrogen and Sulfur Species in Plants written by Mirza Hasanuzzaman and published by John Wiley & Sons. This book was released on 2019-07-02 with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a multidisciplinary analysis of the integration among reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS). Since plants are the main source of our food, the improvement of their productivity is the most important task for plant biologists. In this book, leading experts accumulate the recent development in the research on oxidative stress and approaches to enhance antioxidant defense system in crop plants. They discuss both the plant responses to oxidative stress and mechanisms of abiotic stress tolerance, and cover all of the recent approaches towards understanding oxidative stress in plants, providing comprehensive information about the topics. It also discusses how reactive nitrogen species and reactive sulfur species regulate plant physiology and plant tolerance to environmental stresses. Reactive Oxygen, Nitrogen and Sulfur Species in Plants: Production, Metabolism, Signaling and Defense Mechanisms covers everything readers need to know in four comprehensive sections. It starts by looking at reactive oxygen species metabolism and antioxidant defense. Next, it covers reactive nitrogen species metabolism and signaling before going on to reactive sulfur species metabolism and signaling. The book finishes with a section that looks at crosstalk among reactive oxygen, nitrogen, and sulfur species based on current research done by experts. Presents the newest method for understanding oxidative stress in plants. Covers both the plant responses to oxidative stress and mechanisms of abiotic stress tolerance Details the integration among reactive oxygen species (ROS), reactive nitrogen species (RNS) and reactive sulfur species (RSS) Written by 140 experts in the field of plant stress physiology, crop improvement, and genetic engineering Providing a comprehensive collection of up-to-date knowledge spanning from biosynthesis and metabolism to signaling pathways implicated in the involvement of RONSS to plant defense mechanisms, Reactive Oxygen, Nitrogen and Sulfur Species in Plants: Production, Metabolism, Signaling and Defense Mechanisms is an excellent book for plant breeders, molecular biologists, and plant physiologists, as well as a guide for students in the field of Plant Science.

Molecules to Medicine with mTOR

Author : Kenneth Maiese
Publisher : Academic Press
ISBN 13 : 012802755X
Total Pages : 472 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Molecules to Medicine with mTOR by : Kenneth Maiese

Download or read book Molecules to Medicine with mTOR written by Kenneth Maiese and published by Academic Press. This book was released on 2016-02-21 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecules to Medicine with mTOR: Translating Critical Pathways into Novel Therapeutic Strategies is a one-stop reference that thoroughly covers the mechanistic target of rapamycin (mTOR). mTOR, also known as the mammalian target of rapamycin, is a 289-kDa serine/threonine protein kinase that is ubiquitous throughout the body and has a critical role in gene transcription and protein formation, stem cell development, cell survival and senescence, aging, immunity, tissue regeneration and repair, metabolism, tumorigenesis, oxidative stress, and pathways of programmed cell death that include apoptosis and autophagy. Incorporating a translational medicine approach, this important reference highlights the basic cellular biology of mTOR pathways, presents the role of mTOR during normal physiologic function and disease, and illustrates how the mechanisms of mTOR can be targeted for current and future therapeutic treatment strategies. Coverage of mTOR signaling includes the entire life cycle of cells that impacts multiple systems of the body including those of nervous, cardiovascular, immune, musculoskeletal, endocrine, reproductive, renal, and respiratory origin. Covers the role of mTOR by internationally recognized expert contributors in the field. Provides a clear picture of the complexity of mTOR signaling as well as of the different approaches that could target this pathway at various levels. Includes analysis of the role of mTOR and in both health and disease. Serves as an important resource for a broad audience of healthcare providers, scientists, drug developers, and students in both clinical and research settings.

Amino Acids in Nutrition and Health

Author : Guoyao Wu
Publisher : Springer Nature
ISBN 13 : 303074180X
Total Pages : 227 pages
Book Rating : 4.0/5 (37 download)

DOWNLOAD NOW!

Book Synopsis Amino Acids in Nutrition and Health by : Guoyao Wu

Download or read book Amino Acids in Nutrition and Health written by Guoyao Wu and published by Springer Nature. This book was released on 2021-07-12 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains about amino acids (AAs) which are not only building blocks of protein, but are also signaling molecules as well as regulators of gene expression and the protein phosphorylation cascade. Additionally, AAs are key precursors for syntheses of hormones and low-molecular-weight nitrogenous substances with each having enormous biological importance. For example, physiological concentrations of AA metabolites (e.g., nitric oxide, polyamines, glutathione, taurine, thyroid hormones, and serotonin) are required for cell functions. Growing evidence shows that humans and animals have dietary requirements for all proteinogenic AAs. Mammals, birds, and fish also have species- and age-dependent needs for some AA-related substances. However, elevated levels of other products (e.g., ammonia, homocysteine, H2S, and asymmetric dimethylarginine) are pathogenic factors for neurological disorders, oxidative stress, and cardiovascular disease. Thus, optimal amounts of AAs and their ratios in diets and circulation are crucial for whole-body homeostasis and health. Adequate provision of one or a mixture of functional AAs or metabolites may be beneficial for ameliorating health problems at various stages of the life cycle (e.g., fetal growth restriction, neonatal morbidity and mortality, weaning-associated intestinal dysfunction and wasting syndrome, obesity, diabetes, cardiovascular disease, the metabolic syndrome, and infertility). Dietary supplementation of these nutrients can also optimize the efficiency of metabolic transformations to enhance muscle growth, milk production, and athletic performance, while preventing excess fat deposition and reducing adiposity. Therefore, functional AAs hold great promise in improving the growth, health, and well-being of individuals.

Polyamines

Author : Rubén Alcázar
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (21 download)

DOWNLOAD NOW!

Book Synopsis Polyamines by : Rubén Alcázar

Download or read book Polyamines written by Rubén Alcázar and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides readers with a collection of the latest protocols used by researchers to study polyamines (PA). The chapters in this book cover various topics, such as quantification of different polyamines and conjugates, subcellular localization studies, transport, DNA methylation, ODC regulation, genetic and phenotyping analyses, genome-wide association mapping, polyamine applications and cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Polyamines: Methods and Protocols is a useful reference for researchers looking to advance and stimulate their knowledge of polyamines.

Inhibition of Polyamine Metabolism

Author : Peter McCann
Publisher : Elsevier
ISBN 13 : 0323152325
Total Pages : 398 pages
Book Rating : 4.3/5 (231 download)

DOWNLOAD NOW!

Book Synopsis Inhibition of Polyamine Metabolism by : Peter McCann

Download or read book Inhibition of Polyamine Metabolism written by Peter McCann and published by Elsevier. This book was released on 2012-12-02 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inhibition of Polyamine Metabolism: Biological Significance and Basis for New Therapies provides an overview of the field concerning polyamine biosynthesis inhibitors. The book is comprised of chapters which describe the compounds which are in use; the rationale for the design of such inhibitors; their synthesis and action; their biological effects on mammalian cells and tissues, plants, and microorganisms including protozoal parasites; and a review of the clinical experience with these inhibitors. The major beneficial effect which the wide availability of these inhibitors has had on the field of polyamine research in general is likewise demonstrated. Biochemists, pharmacologist, and cellular physiologists will find this text very useful.