Liquid Chromatography Coupled with Electrospray-ionization Mass Spectrometry and Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry Method Development and Applications for the Analysis of Food and Medicinal Herbs

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ISBN 13 :
Total Pages : 380 pages
Book Rating : 4.:/5 (423 download)

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Book Synopsis Liquid Chromatography Coupled with Electrospray-ionization Mass Spectrometry and Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry Method Development and Applications for the Analysis of Food and Medicinal Herbs by : Kim Chung Lee

Download or read book Liquid Chromatography Coupled with Electrospray-ionization Mass Spectrometry and Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry Method Development and Applications for the Analysis of Food and Medicinal Herbs written by Kim Chung Lee and published by . This book was released on 2009 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Direct Analysis in Real Time Mass Spectrometry

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Publisher : John Wiley & Sons
ISBN 13 : 3527341846
Total Pages : 370 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Direct Analysis in Real Time Mass Spectrometry by : Yiyang Dong

Download or read book Direct Analysis in Real Time Mass Spectrometry written by Yiyang Dong and published by John Wiley & Sons. This book was released on 2018-04-09 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clear, comprehensive, and state of the art, the groundbreaking book on the emerging technology of direct analysis in real time mass spectrometry Written by a noted expert in the field, Direct Analysis in Real Time Mass Spectrometry offers a review of the background and the most recent developments in DART-MS. Invented in 2005, DART-MS offers a wide range of applications for solving numerous analytical problems in various environments, including food science, forensics, and clinical analysis. The text presents an introduction to the history of the technology and includes information on the theoretical background, for exampleon the ionization mechanism. Chapters on sampling and coupling to different types of mass spectrometers are followed by a comprehensive discussion of a broad range of applications. Unlike most other ionization methods, DART does not require laborious sample preparation, as ionization takes place directly on the sample surface. This makes the technique especially attractive for applications in forensics and food science. Comprehensive in scope, this vital text: -Sets the standard on an important and emerging ionization technique -Thoroughly discusses all the relevant aspects from instrumentation to applications -Helps in solving numerous analytical problems in various applications, for example food science, forensics, environmental and clinical analysis -Covers mechanisms, coupling to mass spectrometers, and includes information on challenges and disadvantages of the technique Academics, analytical chemists, pharmaceutical chemists, clinical chemists, forensic scientists, and others will find this illuminating text a must-have resource for understanding the most recent developments in the field.

Liquid Chromatography Time-of-Flight Mass Spectrometry

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Publisher : John Wiley & Sons
ISBN 13 : 047042995X
Total Pages : 281 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Liquid Chromatography Time-of-Flight Mass Spectrometry by : Imma Ferrer

Download or read book Liquid Chromatography Time-of-Flight Mass Spectrometry written by Imma Ferrer and published by John Wiley & Sons. This book was released on 2009-05-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time of flight mass spectrometry identifies the elements of a compound by subjecting a sample of ions to a strong electrical field. Illuminating emerging analytical techniques in high-resolution mass spectrometry, Liquid Chromatography Time-of-Flight Mass Spectrometry shows readers how to analyze unknown and emerging contaminants—such as antibiotics, steroids, analgesics—using advanced mass spectrometry techniques. The text combines theoretical discussion with concrete examples, making it suitable for analytical chemists, environmental chemists, organic chemists, medicinal chemists, university research chemists, and graduate and post-doctorate students.

Development of Matrix-assisted Laser Desorption/ionization and Liquid Chromatography - Electrospray Ionization Based Mass Spectrometric Techniques for Characterizing and Quantifying Endogenous and Therapeutic Biomolecules

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Publisher :
ISBN 13 :
Total Pages : 463 pages
Book Rating : 4.:/5 (988 download)

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Book Synopsis Development of Matrix-assisted Laser Desorption/ionization and Liquid Chromatography - Electrospray Ionization Based Mass Spectrometric Techniques for Characterizing and Quantifying Endogenous and Therapeutic Biomolecules by : Bingming Chen

Download or read book Development of Matrix-assisted Laser Desorption/ionization and Liquid Chromatography - Electrospray Ionization Based Mass Spectrometric Techniques for Characterizing and Quantifying Endogenous and Therapeutic Biomolecules written by Bingming Chen and published by . This book was released on 2017 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endogenous biomolecules, such as neuropeptide, protein and carbohydrates, play important roles in biological and physiological processes. Over the last two decades, therapeutic biomolecules, including therapeutic peptides, proteins and monoclonal antibodies, have become large and fast-growing segments of the pharmaceutical industry. However, analyzing biomolecules is challenging due to their large size, complex structure and various modifications. In situ analysis of biomolecules is even more challenging due to the large dynamic range and complex microenvironments on tissue surface. In this dissertation, matrix-assisted laser desorption/ionization (MALDI) and liquid chromatography (LC) -- electrospray ionization (ESI) based mass spectrometric techniques were developed to characterize and quantify endogenous and therapeutic biomolecules. Specifically, this work developed novel ionization techniques and mass spectrometry imaging workflows to study the sequence and in situ distribution of biomolecules on high resolution accurate mass instrument platforms. Moreover, absolute or relative quantifications of biomolecules, such as therapeutic peptide or N-glycans, were measured by cutting-edge quantification workflows. In summary, this work not only improves current analytical methodology for characterizing biomolecules, but also demonstrates its potential applications in pharmaceutical industry and clinical settings.

Ultra Performance Liquid Chromatography Mass Spectrometry

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Publisher : CRC Press
ISBN 13 : 1466591552
Total Pages : 464 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Ultra Performance Liquid Chromatography Mass Spectrometry by : Mu Naushad

Download or read book Ultra Performance Liquid Chromatography Mass Spectrometry written by Mu Naushad and published by CRC Press. This book was released on 2014-03-18 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a unique collection of up-to-date UPLC-MS/MS (ultra performance liquid chromatography-tandem mass spectrometric) methods for the separation and quantitative determination of pesticides, capsaicinoids, heterocyclic amines, aflatoxin, perfluorochemicals, acrylamide, procyanidins and alkaloids, lactose content, phenolic compounds, vitamins, and aroma and flavor compounds in a wide variety of foods and food products. With contributions by experts in interdisciplinary fields, this reference offers practical information for readers in research and development, production, and routing analysis of foods and food products.

Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 2388 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1828 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Development, assessment, improvement, and standardization of methods in herbal drug research

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Publisher : Frontiers Media SA
ISBN 13 : 2832509088
Total Pages : 175 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Development, assessment, improvement, and standardization of methods in herbal drug research by : Gunawan Indrayanto

Download or read book Development, assessment, improvement, and standardization of methods in herbal drug research written by Gunawan Indrayanto and published by Frontiers Media SA. This book was released on 2022-12-08 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Proceedings of 4th World Congress on Mass Spectrometry 2017

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Publisher : ConferenceSeries
ISBN 13 :
Total Pages : 152 pages
Book Rating : 4./5 ( download)

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Book Synopsis Proceedings of 4th World Congress on Mass Spectrometry 2017 by : ConferenceSeries

Download or read book Proceedings of 4th World Congress on Mass Spectrometry 2017 written by ConferenceSeries and published by ConferenceSeries. This book was released on with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: June 19-21, 2017 London, UK Key Topics : Applications of Mass Spectrometry, New Approaches in Mass Spectrometry, Recent Advances and Development in Mass Spectrometry, Mass spectrometry Imaging, Fundamentals of Mass Spectrometry, Ionization Techniques, Mass Spectrometry Configurations and Separation Techniques, Chromatography and High Performance Liquid Chromatography (HPLC), Maintenance, Troubleshooting, Data Analysis and Experimentation in Mass Spectrometry, Mass Spectrometry in Proteome Research, Proteomics and its applications, Mass Spectrometry in Metabolomics and Lipidomics, Hyphenated Techniques (LC-NMR-MS, HPLC-ESI-MS, MC-ICP-MS, HPLC-ICP-MS, UPLC-Q-TOF/MS), Mass spectrometry in environmental analysis, Spectroscopy, Clinical application of mass spectrometry, UV, IR and Ion Spectroscopy, Nuclear Magnetic Resonance(NMR) Spectroscopy, Mass Spectrometry in Toxicology, Mass spectrometry in Analytical Science, Mass Spectrometry in Pharmaceutical Analysis,

Mass Spectrometry for the Clinical Laboratory

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Publisher : Academic Press
ISBN 13 : 0128009926
Total Pages : 306 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Mass Spectrometry for the Clinical Laboratory by : Hari Nair

Download or read book Mass Spectrometry for the Clinical Laboratory written by Hari Nair and published by Academic Press. This book was released on 2016-11-02 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example. Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing. The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab. Provides readers with the keys to choosing, installing, and validating a mass spectrometry platform Offers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labs Explains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab

Liquid Chromatography Continuous-flow Matrix-assisted Laser Desorption Ionization Time-of-flight Mass Spectrometry for the Detection of Bioactive Peptides and Proteins

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Publisher :
ISBN 13 :
Total Pages : 28 pages
Book Rating : 4.:/5 (932 download)

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Book Synopsis Liquid Chromatography Continuous-flow Matrix-assisted Laser Desorption Ionization Time-of-flight Mass Spectrometry for the Detection of Bioactive Peptides and Proteins by :

Download or read book Liquid Chromatography Continuous-flow Matrix-assisted Laser Desorption Ionization Time-of-flight Mass Spectrometry for the Detection of Bioactive Peptides and Proteins written by and published by . This book was released on 1997 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the general approach of combining liquid chromatography with matrix-assisted laser desorption ionization mass spectrometry for on-line detection of peptides and proteins, based on the use of a continuous flow probe. Recent advances in time-of-flight mass spectrometric instrumentation for this approach are reported. Finally, the results of time-lag focusing matrix-assisted laser desorption ionization analysis of 15 peptides and proteins using solid matrices are presented. Mass measurement error is discussed along with the limitations of, and potential improvements to, the analytical system proposed.

Time-of-flight Mass Spectrometry

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Publisher :
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Time-of-flight Mass Spectrometry by : Robert J. Cotter

Download or read book Time-of-flight Mass Spectrometry written by Robert J. Cotter and published by . This book was released on 1997 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the basic principles of time-of-flight (TOF) mass spectrometry with a strong emphasis on applications in biological research. It describes many innovative techniques, including orthogonal extraction, post source decay, and delayed extraction, and surveys ionization techniques used on TOF mass spectrometers such as electron impact, plasma desorption, SIMS, FAB, laser desorption, MALDI, and electrospray. The book features chapters on applications to peptides/proteins, oligonucleotides, and other biological macromolecules, and examines how techniques might be used in sequencing the human genome.

Plant Metabolomics

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Publisher : Humana
ISBN 13 : 9781493992942
Total Pages : 355 pages
Book Rating : 4.9/5 (929 download)

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Book Synopsis Plant Metabolomics by : Carla António

Download or read book Plant Metabolomics written by Carla António and published by Humana. This book was released on 2019-05-29 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book aims to address the need for standardizing key steps in plant metabolomics research that is still considered a critical issue in the field. The collection unites diverse mass spectrometry (MS)-based protocols, from sample preparation and extraction of plant primary and secondary metabolites (e.g. a range of sugars, lipids, phytohormones and volatile organic compounds) to metabolite analysis, using exclusively highly sensitive MS-based methodologies, followed by frontline bioinformatics and/or mathematical modeling approaches to produce reliable biological data interpretation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Plant Metabolomics: Methods and Protocols serves both new and well-established researchers in the plant metabolomics field in finding helpful guidelines and useful laboratory-based protocols for setting up their routine plant metabolomics experiments.

Analyzing Biomolecular Interactions by Mass Spectrometry

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Publisher : John Wiley & Sons
ISBN 13 : 3527334645
Total Pages : 402 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Analyzing Biomolecular Interactions by Mass Spectrometry by : Jeroen Kool

Download or read book Analyzing Biomolecular Interactions by Mass Spectrometry written by Jeroen Kool and published by John Wiley & Sons. This book was released on 2015-05-04 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.

Development of Novel Interfaces for Combining Liquid Chromatography with Matrix-assisted Laser Desorption Ionization Mass Spectrometry

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Publisher :
ISBN 13 :
Total Pages : 236 pages
Book Rating : 4.:/5 (746 download)

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Book Synopsis Development of Novel Interfaces for Combining Liquid Chromatography with Matrix-assisted Laser Desorption Ionization Mass Spectrometry by : Jason Bryce Young

Download or read book Development of Novel Interfaces for Combining Liquid Chromatography with Matrix-assisted Laser Desorption Ionization Mass Spectrometry written by Jason Bryce Young and published by . This book was released on 2009 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Development of Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry and Its Application to the Study of Polymers and Biopolymers

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (593 download)

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Book Synopsis The Development of Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry and Its Application to the Study of Polymers and Biopolymers by : Sajid Bashir

Download or read book The Development of Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry and Its Application to the Study of Polymers and Biopolymers written by Sajid Bashir and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comprehensive Environmental Mass Spectrometry

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Publisher : ILM Publications
ISBN 13 : 1906799121
Total Pages : 544 pages
Book Rating : 4.9/5 (67 download)

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Book Synopsis Comprehensive Environmental Mass Spectrometry by : Albert Lebedev

Download or read book Comprehensive Environmental Mass Spectrometry written by Albert Lebedev and published by ILM Publications. This book was released on 2012 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In full colour throughout, this book describes the power of mass spectrometry in resolving environmental issues, demonstrating how real-world complex problems can be solved in a simple and elegant way."--Worldcat.