Liquid Chromatography Time Of Flight Mass Spectrometry

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Liquid Chromatography Time-of-Flight Mass Spectrometry

Author : Imma Ferrer
Publisher : John Wiley & Sons
ISBN 13 : 047042995X
Total Pages : 281 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Liquid Chromatography Time-of-Flight Mass Spectrometry by : Imma Ferrer

Download or read book Liquid Chromatography Time-of-Flight Mass Spectrometry written by Imma Ferrer and published by John Wiley & Sons. This book was released on 2009-05-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time of flight mass spectrometry identifies the elements of a compound by subjecting a sample of ions to a strong electrical field. Illuminating emerging analytical techniques in high-resolution mass spectrometry, Liquid Chromatography Time-of-Flight Mass Spectrometry shows readers how to analyze unknown and emerging contaminants—such as antibiotics, steroids, analgesics—using advanced mass spectrometry techniques. The text combines theoretical discussion with concrete examples, making it suitable for analytical chemists, environmental chemists, organic chemists, medicinal chemists, university research chemists, and graduate and post-doctorate students.

Liquid Chromatography/Mass Spectrometry, MS/MS and Time of Flight MS

Author : Imma Ferrer
Publisher : American Chemical Society
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Liquid Chromatography/Mass Spectrometry, MS/MS and Time of Flight MS by : Imma Ferrer

Download or read book Liquid Chromatography/Mass Spectrometry, MS/MS and Time of Flight MS written by Imma Ferrer and published by American Chemical Society. This book was released on 2003-08-14 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores state-of-the-art mass spectrometric techniques. It focuses on liquid chromatography/mass spectrometry/mass spectrometry and time-of-flight/mass spectrometry to determine emerging contaminants, such as pharmaceuticals, hormones, pesticides, surfactants and unknown natural products.

Neuroproteomics

Author : Oscar Alzate
Publisher : CRC Press
ISBN 13 : 9781420076264
Total Pages : 354 pages
Book Rating : 4.0/5 (762 download)

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Book Synopsis Neuroproteomics by : Oscar Alzate

Download or read book Neuroproteomics written by Oscar Alzate and published by CRC Press. This book was released on 2009-10-26 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we begin to unravel the complex mysteries of neurological diseases that less than a generation ago seemed opaque to our inquiries, if not altogether intractable. Edited by Dr. Oscar Alzate, Neuroproteomics is the newest volume in the CRC Press Frontiers of Neuroscience Series. With an extensive background in mathematics and physics, Dr. Alzate exemplifies the newest generation of biological systems researchers. He organizes research and data contributed from all across the world to present an overview of neuroproteomics that is practical and progressive. Bolstered by each new discovery, researchers employing multiple methods of inquiry gain a deeper understanding of the key biological problems related to brain function, brain structure, and the complexity of the nervous system. This in turn is leading to new understanding about diseases of neurological deficit such as Parkinson’s and Alzheimer’s. Approaches discussed in the book include mass spectrometry, electrophoresis, chromatography, surface plasmon resonance, protein arrays, immunoblotting, computational proteomics, and molecular imaging. Writing about their own work, leading researchers detail the principles, approaches, and difficulties of the various techniques, demonstrating the questions that neuroproteomics can answer and those it raises. New challenges wait, not the least of which is the identification of potential methods to regulate the structures and functions of key protein interaction networks. Ultimately, those building on the foundation presented here will advance our understanding of the brain and show us ways to abate the suffering caused by neurological and mental diseases.

Liquid Chromatography - Mass Spectrometry

Author : Robert E. Ardrey
Publisher : John Wiley & Sons
ISBN 13 : 0470862173
Total Pages : 296 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Liquid Chromatography - Mass Spectrometry by : Robert E. Ardrey

Download or read book Liquid Chromatography - Mass Spectrometry written by Robert E. Ardrey and published by John Wiley & Sons. This book was released on 2003-07-25 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: First explaining the basic principles of liquid chromatography and mass spectrometry and then discussing the current applications and practical benefits of LC-MS, along with descriptions of the basic instrumentation, this title will prove to be the indispensable reference source for everyone wishing to use this increasingly important tandem technique. * First book to concentrate on principles of LC-MS * Explains principles of mass spectrometry and chromatography before moving on to LC-MS * Describes instrumental aspects of LC-MS * Discusses current applications of LC-MS and shows benefits of using this technique in practice

Advanced Techniques in Gas Chromatography-Mass Spectrometry (GC-MS-MS and GC-TOF-MS) for Environmental Chemistry

Author :
Publisher : Newnes
ISBN 13 : 0444626247
Total Pages : 525 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Advanced Techniques in Gas Chromatography-Mass Spectrometry (GC-MS-MS and GC-TOF-MS) for Environmental Chemistry by :

Download or read book Advanced Techniques in Gas Chromatography-Mass Spectrometry (GC-MS-MS and GC-TOF-MS) for Environmental Chemistry written by and published by Newnes. This book was released on 2013-09-26 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gas chromatography mass spectrometry (GC-MS) has been the technique of choice of analytical scientists for many years. The latest developments in instrumentation, including tandem mass spectrometry (MS-MS) and time-of-flight (TOF) detectors, have opened up and broadened the scope of environmental analytical chemistry. This book summarizes the major advances and relevant applications of GC-MS techniques over the last 10 years, with chapters by leading authors in the field of environmental chemistry. The authors are drawn from academia, industry and government. The book is organized in three main parts. Part I covers applications of basic GC-MS to solve environmental-related problems. Part II focuses on GC-MS-MS instrumentation for the analyses of a broad range of analysis in environmental samples (pesticides, persistent organic pollutants, endocrine disruptors, etc.). Part III covers the use of more advanced GC-MS techniques using low- and high-resolution mass spectrometry for many applications related to the environment, food and industry. Summarizes the major advances of GC-MS techniques in the last decade Presents relevant applications of GC-MS techniques Covers academic, industrial and governmental sectors

Metabolic Profiling

Author : Georgios A. Theodoridis
Publisher : Humana
ISBN 13 : 9781493992522
Total Pages : 291 pages
Book Rating : 4.9/5 (925 download)

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Book Synopsis Metabolic Profiling by : Georgios A. Theodoridis

Download or read book Metabolic Profiling written by Georgios A. Theodoridis and published by Humana. This book was released on 2019-04-30 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the different approaches and techniques used by researchers to study the recent challenges and developments in metabolic profiling. This book is divided into IV parts. Part I contains chapters that highlight basic concepts, such as experimental design, data treatment, metabolite identification, and harmonization. Part II describes experimental protocols for both targeted and untargeted metabolomics covering the basic analytical technologies: LC-MS, GC-MS, NMR and CE-MS. In addition the protocols describe methods for the study of tissues, feces, blood and other types of biological samples as well as the application of chemical derivatization for GC-MS. Parts III and IV present the use of metabolomics in the study of food, plants and the life sciences, with examples from the quest for the discovery of disease biomarkers, physical exercise omics and metabolic profiling of food, fruit and wine. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Metabolic Profiling: Methods and Protocols is a valuable resource for researchers who are interested in expanding their knowledge of this rapidly developing field.

Mass Spectrometry

Author : Jürgen H Gross
Publisher : Springer Science & Business Media
ISBN 13 : 3540407391
Total Pages : 534 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Mass Spectrometry by : Jürgen H Gross

Download or read book Mass Spectrometry written by Jürgen H Gross and published by Springer Science & Business Media. This book was released on 2006-04-05 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.

Differential Ion Mobility Spectrometry

Author : ALEXANDRE A. SHVARTSBURG
Publisher : CRC Press
ISBN 13 : 9780367577377
Total Pages : 322 pages
Book Rating : 4.5/5 (773 download)

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Book Synopsis Differential Ion Mobility Spectrometry by : ALEXANDRE A. SHVARTSBURG

Download or read book Differential Ion Mobility Spectrometry written by ALEXANDRE A. SHVARTSBURG and published by CRC Press. This book was released on 2020-06-30 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the first books available on this topic of emerging interest, this text explores a new analytical technology that separates and characterizes ions by the difference between their mobility in gases at high and low electric fields. It also covers the novel topics of higher-order differential IMS and IMS with alignment of di

Time-of-flight Mass Spectrometry

Author : Robert J. Cotter
Publisher :
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Time-of-flight Mass Spectrometry by : Robert J. Cotter

Download or read book Time-of-flight Mass Spectrometry written by Robert J. Cotter and published by . This book was released on 1997 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the basic principles of time-of-flight (TOF) mass spectrometry with a strong emphasis on applications in biological research. It describes many innovative techniques, including orthogonal extraction, post source decay, and delayed extraction, and surveys ionization techniques used on TOF mass spectrometers such as electron impact, plasma desorption, SIMS, FAB, laser desorption, MALDI, and electrospray. The book features chapters on applications to peptides/proteins, oligonucleotides, and other biological macromolecules, and examines how techniques might be used in sequencing the human genome.

Mass Spectrometry in Medicinal Chemistry

Author : Klaus Wanner
Publisher : John Wiley & Sons
ISBN 13 : 352761091X
Total Pages : 460 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Mass Spectrometry in Medicinal Chemistry by : Klaus Wanner

Download or read book Mass Spectrometry in Medicinal Chemistry written by Klaus Wanner and published by John Wiley & Sons. This book was released on 2007-06-27 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and analysis of multiple ligand-target interactions. The ready reference opens with a general introduction to the use of mass spectrometry in pharmaceutical screening, followed by a detailed description of recently developed analytical systems for use in the pharmaceutical laboratory. Applications range from simple binding assays to complex screens of biological activity and systems containing multiple targets or ligands -- all highly relevant techniques in the early stages in drug discovery, from target characterization to hit and lead finding.

Analyzing Biomolecular Interactions by Mass Spectrometry

Author : Jeroen Kool
Publisher : John Wiley & Sons
ISBN 13 : 3527334645
Total Pages : 402 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Analyzing Biomolecular Interactions by Mass Spectrometry by : Jeroen Kool

Download or read book Analyzing Biomolecular Interactions by Mass Spectrometry written by Jeroen Kool and published by John Wiley & Sons. This book was released on 2015-05-04 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.

Principles of Forensic Toxicology

Author : Barry Levine
Publisher : Amer. Assoc. for Clinical Chemistry
ISBN 13 : 9781890883874
Total Pages : 406 pages
Book Rating : 4.8/5 (838 download)

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Book Synopsis Principles of Forensic Toxicology by : Barry Levine

Download or read book Principles of Forensic Toxicology written by Barry Levine and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2003 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Phytoplankton Pigments

Author : Suzanne Roy
Publisher : Cambridge University Press
ISBN 13 : 1139500996
Total Pages : pages
Book Rating : 4.1/5 (395 download)

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Book Synopsis Phytoplankton Pigments by : Suzanne Roy

Download or read book Phytoplankton Pigments written by Suzanne Roy and published by Cambridge University Press. This book was released on 2011-10-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Pigments act as tracers to elucidate the fate of phytoplankton in the world's oceans and are often associated with important biogeochemical cycles related to carbon dynamics in the oceans. They are increasingly used in in situ and remote-sensing applications, detecting algal biomass and major taxa through changes in water colour. This book is a follow-up to the 1997 volume Phytoplankton Pigments in Oceanography (UNESCO Press). Since then, there have been many advances concerning phytoplankton pigments. This book includes recent discoveries on several new algal classes particularly for the picoplankton, and on new pigments. It also includes many advances in methodologies, including liquid chromatography-mass spectrometry (LC-MS) and developments and updates on the mathematical methods used to exploit pigment information and extract the composition of phytoplankton communities. The book is invaluable primarily as a reference for students, researchers and professionals in aquatic science, biogeochemistry and remote sensing.

Analysis of Pesticide Residues

Author : H. Anson Moye
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Analysis of Pesticide Residues by : H. Anson Moye

Download or read book Analysis of Pesticide Residues written by H. Anson Moye and published by John Wiley & Sons. This book was released on 1981-02-02 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the latest techniques and applications of pesticide trace analysis. Methods covered include gas, thin layer, and high-performance liquid chromatography, along with their applications in the analysis of chlorinated hydrocarbons, acidic herbicides, organophosphates, carbamates, and insect pheromones and hormones. Includes a special chapter on residue data requirements of government agencies.

Liquid Chromatography

Author : Salvatore Fanali
Publisher : Elsevier
ISBN 13 : 0128093447
Total Pages : 838 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Liquid Chromatography by : Salvatore Fanali

Download or read book Liquid Chromatography written by Salvatore Fanali and published by Elsevier. This book was released on 2017-06-23 with total page 838 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liquid Chromatography: Applications, Second Edition,is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their knowledge of the wide variety of applications in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. Emphasizes the integration of chromatographic methods and sample preparation Explains how liquid chromatography is used in different industrial sectors Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making

Proton Transfer Reaction Mass Spectrometry

Author : Andrew M. Ellis
Publisher : John Wiley & Sons
ISBN 13 : 1118683579
Total Pages : 361 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Proton Transfer Reaction Mass Spectrometry by : Andrew M. Ellis

Download or read book Proton Transfer Reaction Mass Spectrometry written by Andrew M. Ellis and published by John Wiley & Sons. This book was released on 2013-12-17 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proton Transfer Reaction Mass Spectrometry (PTR-MS) is a rapidly growing analytical technique for detecting and identifying very small quantities of chemical compounds in air. It has seen widespread use in atmospheric monitoring and food science and shows increasing promise in applications such as industrial process monitoring, medical science and in crime and security scenarios. Written by leading researchers, this is the first book devoted to PTR-MS and it provides a comprehensive account of the basic principles, the experimental technique and various applications, thus making this book essential reading for researchers, technicians, postgraduate students and professionals in industry. The book contains nine chapters and is divided into two parts. The first part describes the underlying principles of the PTR-MS technique, including • the relevant ion-molecule chemistry • thermodynamics and reaction kinetics • a discussion of ion sources, drift tubes and mass spectrometers • practical aspects of PTR-MS, including calibration. The second part of the book turns its attention to some of the many applications of PTR-MS, demonstrating the scope and benefits, as well as the limitations, of the technique. The chapters that make up the second part of the book build upon the material presented in the first part and are essentially self-contained reviews focusing on the following topics: • environmental science • food science • medicine • homeland security, and • applications of PTR-MS in liquid analysis.

Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis

Author :
Publisher : Elsevier
ISBN 13 : 0444635734
Total Pages : 524 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis by :

Download or read book Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis written by and published by Elsevier. This book was released on 2016-06-02 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis deals with the use of high-resolution mass spectrometry (MS) in the analysis of small organic molecules. Over the past few years, time-of-flight (ToF) and Orbitrap MS have both experienced tremendous growth in a great number of analytical sectors and are now well established in many laboratories where high requirements are placed on analytical performance. This book gives a head-to-head comparison of these two technologies that compete directly with each other. As users with hands-on experience in both techniques, the authors provide a balanced description of the strengths and weaknesses of both techniques. In the vast majority of cases, ToF-MS and Orbitrap-MS have been used for qualitative purposes, mainly identification of discrete molecular entities such as drug metabolites or transformation products of environmental contaminants. This paradigm is now changing as quantitative capabilities are increasingly being explored, as are non-target approaches for unbiased broad-scope screening. In view of the continuous innovation of high-resolution MS instrument manufacturers in designing and developing more powerful machines, technological advances in both hardware and software are considerable, with many novel applications. This book summarizes and analyzes these trends. The compilation of selected examples from diverse analytical fields will allow the readers to discover not only the potential of high-resolution MS in their sector, but also shows advances in other fields that rely on hi-res MS. Provides comprehensive coverage of applications of time-of-flight and orbitrap mass spectrometry in environmental, food, doping, and forensic analysis Explores a variety of specialized techniques, giving a balanced description of the strengths and weaknesses of each Presents a general overview of imaging techniques within analysis