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Introduction To Theoretical Population Genetics
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Book Synopsis Introduction to Theoretical Population Genetics by : Thomas Nagylaki
Download or read book Introduction to Theoretical Population Genetics written by Thomas Nagylaki and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers those areas of theoretical population genetics that can be investigated rigorously by elementary mathematical methods. I have tried to formulate the various models fairly generally and to state the biological as sumptions quite explicitly. I hope the choice and treatment of topics will en able the reader to understand and evaluate detailed analyses of many specific models and applications in the literature. Models in population genetics are highly idealized, often even over idealized, and their connection with observation is frequently remote. Further more, it is not practicable to measure the parameters and variables in these models with high accuracy. These regrettable circumstances amply justify the use of appropriate, lucid, and rigorous approximations in the analysis of our models, and such approximations are often illuminating even when exact solu tions are available. However, our empirical and theoretical limitations justify neither opaque, incomplete formulations nor unconvincing, inadequate analy ses, for these may produce uninterpretable, misleading, or erroneous results. Intuition is a principal source of ideas for the construction and investigation of models, but it can replace neither clear formulation nor careful analysis. Fisher (1930; 1958, pp. x, 23-24, 38) not only espoused similar ideas, but he recognized also that our concepts of intuition and rigor must evolve in time. The book is neither a review of the literature nor a compendium of results. The material is almost entirely self-contained. The first eight chapters are a thoroughly revised and greatly extended version of my published lecture notes (Nagylaki, 1977a).
Book Synopsis The Origins of Theoretical Population Genetics by : William B. Provine
Download or read book The Origins of Theoretical Population Genetics written by William B. Provine and published by University of Chicago Press. This book was released on 2020-07-24 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tracing the development of population genetics through the writings of such luminaries as Darwin, Galton, Pearson, Fisher, Haldane, and Wright, William B. Provine sheds light on this complex field as well as its bearing on other branches of biology.
Book Synopsis Mathematical Population Genetics 1 by : Warren J. Ewens
Download or read book Mathematical Population Genetics 1 written by Warren J. Ewens and published by Springer Science & Business Media. This book was released on 2004-01-09 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.
Book Synopsis Introduction to Population Genetics by : Richard Halliburton
Download or read book Introduction to Population Genetics written by Richard Halliburton and published by Pearson. This book was released on 2004 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Making the theory of population genetics relevant to readers, this book explains the related mathematics with a logical organization. It presents the quantitative aspects of population genetics, and employs examples of human genetics, medical evolution, human evolution, and endangered species. For an introduction to, and understanding of, population genetics.
Book Synopsis Theoretical Population Genetics by : J.S. Gale
Download or read book Theoretical Population Genetics written by J.S. Gale and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rise of the neutral theory of molecular evolution seems to have aroused a renewed interest in mathematical population genetics among biologists, who are primarily experimenters rather than theoreticians. This has encouraged me to set out the mathematics of the evolutionary process in a manner that, I hope, will be comprehensible to those with only a basic knowledge of calculus and matrix algebra. I must acknowledge from the start my great debt to my students. Equipped initially with rather limited mathematics, they have pursued the subject with much enthusiasm and success. This has enabled me to try a number of different approaches over the years. I was particularly grateful to Dr L. J. Eaves and Professor W. E. Nance for the opportunity to give a one-semester course at the Medical College of Virginia, and I would like to thank them, their colleagues and their students for the many kindnesses shown to me during my visit. I have concentrated almost entirely on stochastic topics, since these cause the greatest problems for non-mathematicians. The latter are particularly concerned with the range of validity of formulae. A sense of confidence in applying these formulae is, almost certainly, best gained by following their derivation. I have set out proofs in fair detail, since, in my experience, minor points of algebraic manipulation occasionally cause problems. To avoid loss of continuity, I have sometimes put material in notes at the end of chapters.
Book Synopsis An Introduction to Population Genetics by : Rasmus Nielsen
Download or read book An Introduction to Population Genetics written by Rasmus Nielsen and published by Sinauer. This book was released on 2013-07-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers both classical population genetics theory developed in terms of allele and haplotype frequencies and modern population genetics theory developed in terms of coalescent theory. It features applications of theory to problems that arise in the study of human and other populations and assumes little prior knowledge of mathematics.
Book Synopsis Population Genetics and Microevolutionary Theory by : Alan R. Templeton
Download or read book Population Genetics and Microevolutionary Theory written by Alan R. Templeton and published by John Wiley & Sons. This book was released on 2006-09-29 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links
Book Synopsis An Introduction to Population Genetics Theory by : J.F. Crow
Download or read book An Introduction to Population Genetics Theory written by J.F. Crow and published by Scientific Publishers. This book was released on 2017-01-01 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text book, originally published in 1970, presents the field of population genetics, starting with elementary concepts and leading the reader well into the field. It is concerned mainly with population genetics in a strict sense and deals primarily with natural populations and less fully with the rather similar problems that arise in breading live stock and cul t i vat ed plans . The emphasis is on the behavior of genes and population attributes under natural selection where the most important measure is Darwinian fitness. This text is intended for graduatestudents and advanced undergraduates in genetics and population biology. This book steers a middle course between completely verbal biological arguments and the rigor of the mathematician. The first two-thirds of the book do not require advanced mathematical background. An ordinary knowledge of calculus will suffice. The latter parts of the book, which deal with population stochastically, use more advanced methods.
Book Synopsis Population Genetics, Molecular Evolution, and the Neutral Theory by : Motoo Kimura
Download or read book Population Genetics, Molecular Evolution, and the Neutral Theory written by Motoo Kimura and published by University of Chicago Press. This book was released on 1994 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.
Book Synopsis An Introduction to Population Genetics Theory by : James F. Crown (E. A. P.)
Download or read book An Introduction to Population Genetics Theory written by James F. Crown (E. A. P.) and published by . This book was released on 1970 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mathematical Population Genetics 1 by : Warren J. Ewens
Download or read book Mathematical Population Genetics 1 written by Warren J. Ewens and published by Springer Science & Business Media. This book was released on 2012-10-01 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.
Book Synopsis Theories of Population Variation in Genes and Genomes by : Freddy Bugge Christiansen
Download or read book Theories of Population Variation in Genes and Genomes written by Freddy Bugge Christiansen and published by Princeton University Press. This book was released on 2014-11-23 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an authoritative introduction to both classical and coalescent approaches to population genetics. Written for graduate students and advanced undergraduates by one of the world's leading authorities in the field, the book focuses on the theoretical background of population genetics, while emphasizing the close interplay between theory and empiricism. Traditional topics such as genetic and phenotypic variation, mutation, migration, and linkage are covered and advanced by contemporary coalescent theory, which describes the genealogy of genes in a population, ultimately connecting them to a single common ancestor. Effects of selection, particularly genomic effects, are discussed with reference to molecular genetic variation. The book is designed for students of population genetics, bioinformatics, evolutionary biology, molecular evolution, and theoretical biology--as well as biologists, molecular biologists, breeders, biomathematicians, and biostatisticians. Contains up-to-date treatment of key areas in classical and modern theoretical population genetics Provides in-depth coverage of coalescent theory Discusses genomic effects of selection Gives examples from empirical population genetics Incorporates figures, diagrams, and boxed features throughout Includes end-of-chapter exercises Speaks to a wide range of students in biology, bioinformatics, and biostatistics
Download or read book Population Genetics written by J. S. Gale and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: POPULATION GENETICS IS OFTEN THOUGHT TO BE A DIFFICULT SUBJECT. To some extent, difficulties are inevitable in a field where some quite basic points are controversial. However, problems are most acute when theoretical points are discussed, despite the fact that there has been very little controversy over the mathematics. In my experience, the actual mathematical manipulations rarely cause much difficulty. Rather it is that the biologist, lacking the physicist's or chemist's experience in "reading" mathematical formulae, finds it difficult to appreciate what is happening in a mathematical treatment and to grasp the implications of the results obtained, when these are given in mathematical form. Accordingly, I have followed a procedure, which students seem to find helpful, of giving a rough-and-ready verbal treatment of a problem before attempting a much more exact mathematical treatment; when the results of the latter are not readily interpretable, I have given an elucidation. Another problem which often concerns students is the reliability of results obtained using approximate methods; I have, therefore, discussed this in fair detail in critical cases. When dealing with controversial issues, I have done my very best to be fair. To conceal one's opinions entirely would probably make for a very dull book. I trust, however, that I have given enough for the reader previously unfamiliar with these controversies to form his own judge ment.
Book Synopsis An Introduction to Population Genetics Theory by : James F. Crow
Download or read book An Introduction to Population Genetics Theory written by James F. Crow and published by . This book was released on 2013 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Population Genetics by : John H. Gillespie
Download or read book Population Genetics written by John H. Gillespie and published by JHU Press. This book was released on 2004-08-06 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description
Book Synopsis Human Population Genetics and Genomics by : Alan R. Templeton
Download or read book Human Population Genetics and Genomics written by Alan R. Templeton and published by Academic Press. This book was released on 2018-11-08 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. Comprehensively explains the use of population genetics and genomics in medical applications and research Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now
Download or read book Coalescent Theory written by John Wakely and published by Roberts. This book was released on 2016-04-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides the foundation for molecular population genetics and genomics. It shows the conceptual framework for studies of DNA sequence variation within species, and is the source of essential tools for making inferences about mutation, recombination, population structure and natural selection from DNA sequence data.
