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Immunological Alterations In Psychiatric Diseases
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Author :A. Henneberg Publisher :Karger Medical and Scientific Publishers ISBN 13 :9783805563840 Total Pages :132 pages Book Rating :4.5/5 (638 download)
Book Synopsis Immunological Alterations in Psychiatric Diseases by : A. Henneberg
Download or read book Immunological Alterations in Psychiatric Diseases written by A. Henneberg and published by Karger Medical and Scientific Publishers. This book was released on 1997 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: In addition, fundamental questions concerning the bi-directional interactions between the central nervous system and the immune system are discussed and the role of viruses and infectious processes closely examined. As such, this book offers a unique presentation of the state of the art in psychoimmunology and, at the same time, shows many important challenges for future research into the field of intersystemic interactions and their impact on the etiology and pathogenesis of psychiatric diseases.
Book Synopsis Immunological Alterations in Psychiatric Diseases by : A. Henneberg
Download or read book Immunological Alterations in Psychiatric Diseases written by A. Henneberg and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past three decades psychiatric research has made use of the expertise and techniques of many medical disciplines, among them neuroendocrinology, immunology, virology, genetics, and molecular biology. This book provides a concise overview of our present knowledge on the immunological aspects of psychiatric diseases, in particular schizophrenia, drug addiction and Alzheimer's disease. In addition, fundamental questions concerning the bi-directional interactions between the central nervous system and the immune system are discussed and the role of viruses and infectious processes closely examined. As such, this book offers a unique presentation of the state of the art in psychoimmunology and, at the same time, shows many important challenges for future research into the field of intersystemic interactions and their impact on the etiology and pathogenesis of psychiatric diseases. Psychiatrists and neurologists will gain a better understanding of the biological basis of psychiatric diseases while immunologists, neuroimmunologists, neurobiologists, neuroendocrinologists and virologists will find it a valuable source of new information on psychoimmunology research.
Book Synopsis Immunopsychiatry by : Antonio L. Teixeira
Download or read book Immunopsychiatry written by Antonio L. Teixeira and published by Oxford University Press. This book was released on 2019-01-03 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, a dedicated effort has been made to understand the immune dysfunction that is associated with major psychiatric disorders. The expanding knowledge of the immune system as a major homeostatic system has been very helpful in indicating new potential biomarkers and therapeutic targets to reduce the burden of psychiatric disorders. Indeed, immune cells, their secreted molecules, and cell signalling events are highly promising. Yet, the literature on immunology of psychiatric disorders is still dispersed, and only a few attempts have been made to consolidate the current knowledge in this expanding area. This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice. An international team of senior experts in the field review all psychiatric disorders in order to provide an integrated, in-depth understanding of the role of immune changes in psychiatric diseases for mental health clinicians as well as for researchers in immunology, psychiatry, neurology, and pharmacology.
Book Synopsis The Immune System and Mental Health by : Hymie Anisman
Download or read book The Immune System and Mental Health written by Hymie Anisman and published by Academic Press. This book was released on 2018-07-19 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immune System and Mental Health fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. Sociology, psychology, psychiatry, neuroscience and genetics have provided considerable explanations and solutions to some of the most intractable mental-health problems. But researchers are increasingly relying on investigations of the immune system to identify factors that can undermine and impair mental health. This book covers devastating mental-health conditions, such as depression, anxiety, schizophrenia, and autism-like spectrum disorders. In addition, degenerative disorders of the brain, such as Parkinson’s and Alzheimer’s-like dementia are explored. Considers both basic human and animal studies that address immunological changes relating to mental health problems across the lifespan Incorporates techniques, concepts and ideas from a variety of social, behavioral and life sciences Explores the relatively new area of the microbiome and how the microbial composition of the gut influences brain function and mental health
Download or read book Immuno-Psychiatry written by Michael Berk and published by Springer Nature. This book was released on 2021-08-14 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a thorough and critical review of current knowledge on the role of immunology in major psychiatric disorders and its potential applications. The opening chapters offer general information on the immune influence of the brain to provide readers with a better understanding of the end of immune privilege. The book then examines possible underlying mechanisms leading to psychiatric disorders, from early infections to pro-inflammatory markers, stress, and immune genetic background, linking etiology and psychiatry. The third section describes each disorder (ie autism, schizophrenia, bipolar disorder, depression...) with an overview of underlying immune dysfunctions. Lastly, the authors discuss the innovative immune-therapies that may result from the discovery of immune system biomarkers and their associated mechanisms. A better understanding of the role of the immune system in psychiatric disorders makes it possible to identify stratification biomarkers, to explain underlying mechanisms, and to develop innovative, efficient, targeted treatment strategies and management. As such, the book is of value to clinicians, mental health professionals, mental health researchers, immunologists, industry practitioners, and various stakeholders in the mental health field.
Book Synopsis Immunology and Psychiatry by : Norbert Müller
Download or read book Immunology and Psychiatry written by Norbert Müller and published by Springer. This book was released on 2015-04-20 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychiatric disorders are one of the most dramatic burdens for humankind. The role of immune dysfunction in the pathophysiology of these disorders has emerged during the last years, because there has been tremendous progress in psychoneuroimmunological research. Many results are presented here by pioneers in the field. The book addresses various effects of the immune system on the pathophysiology and course of psychiatric disorders and highlights the possible future impact on treatment decisions of various psychiatric disorders, including schizophrenia and depression. The contributions cover the role of in utero immune challenges on the development of schizophrenia, the role of infections, and autoimmune diseases and mild immune activation in the development of depression and schizophrenia, the influence of immune responses in other disorders such as Tourette's, Alzheimer's, and OCD, the connections between mental and physical pain as well as between anti-inflammatory and antipsychotic drugs.
Book Synopsis Peripheral Markers of Immune Response in Major Psychiatric Disorders: Where Are We Now and Where Do We Want to Be? by : Błażej Misiak
Download or read book Peripheral Markers of Immune Response in Major Psychiatric Disorders: Where Are We Now and Where Do We Want to Be? written by Błażej Misiak and published by Frontiers Media SA. This book was released on 2019-04-03 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major psychiatric disorders, including schizophrenia, bipolar disorder and major depression represent complex phenotypes with imprecise diagnostic boundaries. It has been found that these disorders can be characterized by a number of peripheral immune-inflammatory alterations, including, i.e. elevated levels of pro-inflammatory cytokines, increased levels of specific and non-specific antibodies or abnormal counts of lymphocyte subpopulations. Although it has been found that major psychiatric disorders share similar dysregulations of immune-inflammatory response, recent studies have also clearly demonstrated that some differences can be indicated. Interestingly, certain immune-inflammatory disturbances appear to be state markers, since they occur in acute relapse and normalize following pharmacological treatment, while the rest represents trait markers that remain stable regardless of treatment. It is also important to note that peripheral immune-inflammatory markers have been associated with psychopathological manifestation of major psychiatric disorders, response to treatment and long-term outcomes. However, it remains unclear what is the origin of peripheral inflammation in psychiatric disorders. To date, several mechanisms have been proposed, including the gut-brain axis dysregulation, infections in the neurodevelopmental period or immunogenetic factors. This eBook summarizes current evidence from studies investigating peripheral inflammation in schizophrenia, bipolar disorder, major depression and post-traumatic stress disorder as well as it provides future directions for the field.
Book Synopsis Psychiatry, Psychoimmunology, and Viruses by : Norbert Müller
Download or read book Psychiatry, Psychoimmunology, and Viruses written by Norbert Müller and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the contributions to the "3rd Expert Meeting in Psychoneuroimmunology", held in Munich, Germany in autumn 1997. Clinical psychiatrists, neuroscientists and researchers in basic immuno logy from Europe and the USA gather together annually at this new tra ditional meeting to discuss new findings and trends in the relationship between psychiatric disorders and the immune system. Pinpointed at the Munich meeting in particular were the possible influence of viral infec tions on psychiatric disorders, especially schizophrenia, and the possible pathophysiological mechanisms affecting psychiatric disorders. These mechanisms include viral-induced alteration, cytokine production, and the role of the HLA system. One chapter is devoted to the influence of viral infections during pregnancy; another to the first results of experimental therapy especial ly regarding the immune system. The immunological aspects not only of schizophrenia but also of depression, anxiety disorders, sleep and headache were also discussed at the meeting, and two further chapters cover methodological aspects related to clinical and experimental pitfalls in psychoneuroimmunology. The psychoneuroimmunology of psychiatric disorders is a rapidly expanding field, and research is increasing on the therapeutic aspects. This is reflected by one of the main themes of the "4th Expert Meeting in Psychoneuroimmunology", jointly held in autumn 1998 in Bethesda, Maryland, USA, with the Stanley Foundation Meeting in Neurovirology, devoted to therapeutic strategies deriving from psychoneuroimmunolo gical findings. The "5th Expert Meeting in Psychoneuroimmunology" will be held in 1999 in Innsbruck, Austria.
Book Synopsis The Role of Immune Components in Psychiatric Disorders by : Marion Leboyer
Download or read book The Role of Immune Components in Psychiatric Disorders written by Marion Leboyer and published by Frontiers Media SA. This book was released on 2020-10-09 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Neuroimmunological Basis of Behavior and Mental Disorders by : Allan Siegel
Download or read book The Neuroimmunological Basis of Behavior and Mental Disorders written by Allan Siegel and published by Springer Science & Business Media. This book was released on 2008-11-09 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, the immune and central nervous systems were thought to function independently with little or no interaction between the two. This view has und- gone dramatic changes over the past three decades. Indeed, we now know that there exists various feedback loops between the brain and immune systems that impact signi cantly upon different behavioral processes, including normal behavior and mental disorders. Pioneering efforts in generating this change were initiated by a number of early investigators. Included were those whose efforts were directed at establishing neuroimmune connections as well as others whose research focused upon the relationship between immunity, cytokines, and behavior. This book brings together outstanding scientists and clinicians who have made major contributions to the rapidly developing eld investigating the relationship between immunity and behavior. The book is divided into three parts. The rst part describes pathways by which the brain and immune systems communicate and int- act with each other. In the chapter “Cytokines and the Blood–Brain Barrier” p- vides insight into interactions between the blood–brain barrier and cytokines. Such interactions underlie basic communication between the immune system and brain that are present in normal as well as in disease conditions. In the chapter “Neu- chemical and Endocrine Responses to Immune Activation: The Role of Cytokines,” the neurochemical and endocrine consequences of immune challenge and cytokine administration on central neurotransmitter activity are discussed.
Book Synopsis Current Update in Psychoimmunology by : Gerhard Wieselmann
Download or read book Current Update in Psychoimmunology written by Gerhard Wieselmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book tries to close the gap between immunological findings on the one hand, psychological, psychopathological, electrophysiological and neuroimaging aspetcs on the other. It deals with the issue of "cause and effect” (of immunological alternatives) in different organic and/or mental disorders, and emphasizes the necessity of considering a variety of treatment strategies. There are dynamic interactions and several important similarities between the immune system and the central nervous system, which help to lay the rational basis for "psychoimmunology”. Both systems have the capacity for memory and both play vital roles in adaptation and defence. Furthermore, in each system pathological changes can occur in the event of inappropriate responses to internal or external stimuli, leading to psychiatric as well as organic illnesses and autoimmune diseases could also arise as a consequence of dysfunction respectively maladaptation. "... this book is a good way to approach the field of psychoimmunology, and shows that scientists are very active in this domain ...” Acta Neurologica Belgica.
Book Synopsis Recent Advances in Psychiatry from Psycho-Neuro-Immunology Research: Autoimmunencephalitis, Autoimmune-Encephalopathy, Mild Encephalitis by : Karl Bechter
Download or read book Recent Advances in Psychiatry from Psycho-Neuro-Immunology Research: Autoimmunencephalitis, Autoimmune-Encephalopathy, Mild Encephalitis written by Karl Bechter and published by Frontiers Media SA. This book was released on 2019-08-12 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Growing evidence derived from cerebrospinal fluid (CSF), neuropathological, imaging, genetic, and epidemiological studies link neuroinflammation and immune dysregulation to a subset of individuals with a variety of severe mental disorders (SMDs), including affective and non-affective psychotic disorders. Further, the recent discoveries of neuronal surface antibodies (NSAs) in autoimmune encephalitis (AE) presenting with diverse neuropsychiatric disorders such as psychosis and cognitive decline, among many others, provides further support to the notion that CNS autoimmunity and neuroinflammation can contribute to the neurobiology of psychiatric disturbances. Further, these immune mechanisms may contribute to a subset of patients currently diagnosed as having treatment-resistant SMDs such as schizophrenia and major depressive disorder. Additionally, mounting data indicate that various infections can serve as an immunological trigger of aberrant immune responses, presumably by causing release of excess neural antigen, thereby giving rise to NSAs or aberrant immune cellular responses to give rise to primary or secondary psychiatric disorders such as schizophrenia and those associated with AE, respectively. Collectively, these findings support the “mild encephalitis” hypothesis of SMD. The significant overlap among AE-associated psychosis, systemic autoimmune disorder-associated psychosis, and psychotic disorders associated with pathological processes involving inflammation and immune dysregulation has also prompted some authors to adopt the term “autoimmune psychosis” (AP). This term reflects that this psychosis subtype is mechanistically linked to complex neuroimmune and inflammatory signalling abnormalities that can be responsive to early immunomodulatory treatment. It also suggests that a subset of AP might represent an incomplete or “forme fruste” subtype of AE presenting with dominant or pure psychiatric symptoms mimicking primary psychiatric illnesses. Because data indicate that delayed diagnosis and treatment may lead to permanent sequelae, early recognition of AP utilizing neurodiagnostic workup (e.g., CSF analysis, neuroimaging, and EEG) and its early treatment with appropriate immunotherapy are paramount to a meaningful recovery. This eBook will provide an overview of the current knowledge and research areas from epidemiology, risk factors and diagnosis to the management of these conditions, in this rapidly emerging field, helping to bridge the gaps in knowledge that currently exist in the disciplines of Psychiatry, Neurology, and Neuroimmunology.
Book Synopsis Cellular and Molecular Immunology E-Book by : Abul K. Abbas
Download or read book Cellular and Molecular Immunology E-Book written by Abul K. Abbas and published by Elsevier Health Sciences. This book was released on 2011-04-15 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Immunology takes a comprehensive yet straightforward approach to the latest developments in this active and fast-changing field. Drs. Abul K. Abbas, Andrew H. Lichtman, and Shiv Pillai present sweeping updates in this new edition to cover antigen receptors and signal transduction in immune cells, mucosal and skin immunity, cytokines, leukocyte-endothelial interaction, and more. This reference is the up-to-date and readable textbook you need to master the complex subject of immunology. Recognize the clinical relevance of the immunology through discussions of the implications of immunologic science for the management of human disease. Grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions. Stay abreast of the latest advances in immunology and molecular biology through extensive updates that cover cytokines, innate immunity, leukocyte-endothelial interactions, signaling, costimulation, and more. Visualize immunologic processes more effectively through a completely revised art program with redrawn figures, a brighter color palette, and more 3-dimensional art. Find information more quickly and easily through a reorganized chapter structure and a more logical flow of material.
Book Synopsis Textbook of Immunopsychiatry by : Golam Khandaker
Download or read book Textbook of Immunopsychiatry written by Golam Khandaker and published by Cambridge University Press. This book was released on 2021-09-23 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly growing field of immunopsychiatry combines expertise and insights from immunology, psychiatry and neuroscience to understand the role of inflammation and other immune processes in causing and treating mental illness. This represents a major shift in mental health science, traditionally focused on psychological and neuronal mechanisms of depression, psychosis and dementia. This book provides the first comprehensive overview of recent, inter-disciplinary research linking disordered function of the immune system to the brain and mental illness. It offers a broad and deep perspective on the implications of immune system involvement in psychiatric disorders, including a balanced focus on basic science and clinical applications. Chapters cover the scientific evidence linking immune processes to major mental illnesses such as schizophrenia, depression, anxiety and dementia. An invaluable guide for graduate students, doctors in training, scientific researchers and others interested in the link between the immune system and mental health.
Book Synopsis Cytokines, Stress, and Depression by : Robert Dantzer
Download or read book Cytokines, Stress, and Depression written by Robert Dantzer and published by Springer Science & Business Media. This book was released on 1999-07-31 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until a few years ago, cytokines were only known to immunologists; now these molecules have burst upon neurosciences and permeated several avenues of current research. This book examines the possible role of cytokines in mental depression, based on recent clinical and experimental data, and constitutes the first attempt to make a synthesis between the exciting new developments in cytokine research and their implications for the pathophysiology of mental disorders.
Download or read book Psychosis written by Kenjiro Fukao and published by BoD – Books on Demand. This book was released on 2022-02-02 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychosis has been the central subject of psychiatric research for more than a century and yet it remains an intriguing enigma. This volume reviews the current status of research on psychosis in three different aspects, namely, phenomenology, which is the philosophical/conceptual basis of psychosis; psychopathology, which is the clinical manifestations of psychosis; and pathophysiology, which is the scientific pursuit for the mechanism of psychosis. Chapters focus on schizophrenia, covering such topics as clinical staging, negative symptoms, epigenetics, DNA methyltransferases, and more.
Book Synopsis Psychotic Disorders by : Carol A. Tamminga MD
Download or read book Psychotic Disorders written by Carol A. Tamminga MD and published by Oxford University Press. This book was released on 2020-10-20 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychotic Disorders: Comprehensive Conceptualization and Treatments emphasizes a dimensional approach to psychosis--one of the most fascinating manifestations of altered brain behavior--that cuts across a broad array of psychiatric diagnoses from schizophrenia to affective psychosis and organic disorders like epilepsy and dementias. Written by an international roster of over seventy leading experts in the field, this volume comprehensively reviews, critiques, and integrates available knowledge on the etiology, mechanisms, and treatments of psychotic disorders, and outlines ways forward in both research and clinical practice towards more objective, mechanistically-based definitions of psychotic disorders. Chapters address topics such as psychosis phenomenology, biomarkers and treatments, the overlaps and interfaces between psychiatric disorders within the psychosis dimension, and novel disease definitions. Furthermore, the volume incorporates findings on potential mechanisms, bridges between various system levels (i.e., genetic, epigenetic, molecular and cellular, brain circuit and function, psychological, social, environmental and cultural) and their interactions, as well as the potential role in causation and/or mediation in psychotic disorders. Finally, the volume outlines a broad array of treatment approaches, from the readily available (e.g., psychopharmacology, various modalities of psychotherapy) to the experimental (e.g., cognitive interventions, neuromodulation). With a concluding section of forward perspectives conjecturing future directions and related challenges, this book aspires to stimulate new knowledge, generate novel frameworks, and carry new directions forward on psychotic disorders.
