GABA and the Basal Ganglia

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Author :
Publisher : Elsevier
ISBN 13 : 0080480470
Total Pages : 350 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis GABA and the Basal Ganglia by : J. M. Tepper

Download or read book GABA and the Basal Ganglia written by J. M. Tepper and published by Elsevier. This book was released on 2007-04-17 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 25 years the amount of data pertaining to the GABAergic function in the basal ganglia has increased dramatically. GABA and the Basal Ganglia - From Molecules to Systems is a comprehensive review of the current state-of-the-art of knowledge about the neuroanatomy, neuropharmacology and neurophysiology of the basal ganglia, focusing on its GABAergic microcircuitry. It serves as a complete reference to the body of knowledge about the basal ganglia, its constituent neurons, and their interconnections. This volume is designed to serve as a convenient all-in-one review and reference for experienced basal ganglia researchers as well as an introduction to the functional organization of the basal ganglia and its GABAergic circuitry for students and researchers new to the field.* Reviews the anatomy, physiology and pharmacology of the basal ganglia itself in addition to focusing on the GABAergic circuitry of the basal ganglia* Authors of each chapter leading internationally acclaimed experts in basal ganglia research

Foundations of Neuroscience

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Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (125 download)

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Book Synopsis Foundations of Neuroscience by : Casey Henley

Download or read book Foundations of Neuroscience written by Casey Henley and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

The GABA Receptors

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Publisher : Humana Press
ISBN 13 : 9781588298133
Total Pages : 325 pages
Book Rating : 4.2/5 (981 download)

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Book Synopsis The GABA Receptors by : Salvatore J. Enna

Download or read book The GABA Receptors written by Salvatore J. Enna and published by Humana Press. This book was released on 2007-07-19 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Gaba Receptors, Third Edition, presents a critical appraisal of our current understanding of the molecular, behavioral, biochemical, clinical, and pharmacological properties of GABA receptors. Emphasis is placed on exploring cutting-edge findings on the structureal properties of receptor sites, mechanisms of receptor expression, chemical agents that differentiate receptor subtypes, and phenotypes displayed by GABA receptor null mice. Chapters in this updated and expanded edition examine such topics as GABA receptor subypes, trafficking postsynaptic GABA receptors, GABA receptor mutations associated with idiopathic generalized epilepsies and febrile seizures, and GABA receptors as a potential therapeutic target.

The Brain and Behavior

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Publisher : Cambridge University Press
ISBN 13 : 9780521840507
Total Pages : 290 pages
Book Rating : 4.8/5 (45 download)

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Book Synopsis The Brain and Behavior by : David L. Clark

Download or read book The Brain and Behavior written by David L. Clark and published by Cambridge University Press. This book was released on 2005-09-08 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition building on the success of previous one. Retains core aim of providing an accessible introduction to behavioral neuroanatomy.

GABA And Glutamate

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535138219
Total Pages : 139 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis GABA And Glutamate by : Janko Samardzic

Download or read book GABA And Glutamate written by Janko Samardzic and published by BoD – Books on Demand. This book was released on 2018-03-21 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collates the contributions of a selected number of neuroscientists that are interested in the molecular, preclinical, and clinical aspects of neurotransmission research. The seven chapters in this book address the latest research/review data related to GABA/glutamate system's organization and function, the structure of receptors, subtypes and their ligands, as well as the translational approach and clinical implications. The book offers readers a rich collection of data regarding current and future applications of GABA and glutamate neurotransmission, including promising research strategies and potential clinical benefits.

Jasper's Basic Mechanisms of the Epilepsies

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Author :
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey Noebels

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Basic Neurochemistry

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Author :
Publisher : Lippincott Raven
ISBN 13 :
Total Pages : 1216 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Basic Neurochemistry by : George J. Siegel

Download or read book Basic Neurochemistry written by George J. Siegel and published by Lippincott Raven. This book was released on 1999 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.

Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System

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Publisher : National Academies Press
ISBN 13 : 0309212219
Total Pages : 74 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System by : Institute of Medicine

Download or read book Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System written by Institute of Medicine and published by National Academies Press. This book was released on 2011-08-05 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.

Acute Topics in Sport Nutrition

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805599935
Total Pages : 166 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Acute Topics in Sport Nutrition by : M. Lamprecht

Download or read book Acute Topics in Sport Nutrition written by M. Lamprecht and published by Karger Medical and Scientific Publishers. This book was released on 2012-10-17 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: In high-performance sport an optimal diet and nutritional interventions can make the difference between victory and defeat. In recent years, sport nutrition research has increased. This publication provides scientifically-based information with regard to the bioefficacy of trendy sport supplements and dietary approaches off the mainstream. International experts in the specific fields inform and clarify under which circumstances the application of certain supplements and nutritional interventions would be beneficial, either for the performance or health of the athletes. A broad spectrum of recent topics in sport nutrition is provided: selected sport supplements aside of mainstream, nutritional interventions and athlete‘s health, hydration and fluid balance and current aspects in exercise and exercise recovery. Finally, the publication concludes with recent information about the risk of supplementation and inadvertent doping. The book will be of benefit to sport physicians and scientists, nutritionists, coaches and athletes, as well as to the sport nutrition trade and related industries.

The Basal Ganglia VIII

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9780387280653
Total Pages : 694 pages
Book Rating : 4.2/5 (86 download)

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Book Synopsis The Basal Ganglia VIII by : International Basal Ganglia Society. Symposium

Download or read book The Basal Ganglia VIII written by International Basal Ganglia Society. Symposium and published by Springer Science & Business Media. This book was released on 2005-12-21 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the International Meetings of the Basal Ganglia Society (IBAGS) is to provide a unique environment for the open presentation and discussion of new and challenging information about the basal ganglia as it relates to health and disease, covering all areas of basic science and research. Specific topics of the proceedings of this Eighth International Triennial Meeting of the Basal Ganglia Society include behavior, circuitry, functional imaging, modelling, movement disorders, neuropathology, neurotransmitters, pharmacology, physiology, plasticity, treatments for basal ganglia disorders, ventral systems, health and disease, immunology and basal ganglia, and much more.

The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy

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Author :
Publisher : Springer
ISBN 13 : 331919285X
Total Pages : 154 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy by : Udo Rüb

Download or read book The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy written by Udo Rüb and published by Springer. This book was released on 2015-09-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.

Dopamine-Gaba Interactions

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Publisher :
ISBN 13 :
Total Pages : 54 pages
Book Rating : 4.:/5 (421 download)

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Book Synopsis Dopamine-Gaba Interactions by : J. Scheel-Krüger

Download or read book Dopamine-Gaba Interactions written by J. Scheel-Krüger and published by . This book was released on 1986 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ontology-Based Information Retrieval for Healthcare Systems

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Publisher : John Wiley & Sons
ISBN 13 : 1119641381
Total Pages : 384 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Ontology-Based Information Retrieval for Healthcare Systems by : Vishal Jain

Download or read book Ontology-Based Information Retrieval for Healthcare Systems written by Vishal Jain and published by John Wiley & Sons. This book was released on 2020-07-29 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the advancements of semantic web, ontology has become the crucial mechanism for representing concepts in various domains. For research and dispersal of customized healthcare services, a major challenge is to efficiently retrieve and analyze individual patient data from a large volume of heterogeneous data over a long time span. This requirement demands effective ontology-based information retrieval approaches for clinical information systems so that the pertinent information can be mined from large amount of distributed data. This unique and groundbreaking book highlights the key advances in ontology-based information retrieval techniques being applied in the healthcare domain and covers the following areas: Semantic data integration in e-health care systems Keyword-based medical information retrieval Ontology-based query retrieval support for e-health implementation Ontologies as a database management system technology for medical information retrieval Information integration using contextual knowledge and ontology merging Collaborative ontology-based information indexing and retrieval in health informatics An ontology-based text mining framework for vulnerability assessment in health and social care An ontology-based multi-agent system for matchmaking patient healthcare monitoring A multi-agent system for querying heterogeneous data sources with ontologies for reducing cost of customized healthcare systems A methodology for ontology based multi agent systems development Ontology based systems for clinical systems: validity, ethics and regulation

Obsessive-compulsive Disorder

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Publisher : Oxford University Press
ISBN 13 : 0190228164
Total Pages : 777 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Obsessive-compulsive Disorder by : Christopher Pittenger

Download or read book Obsessive-compulsive Disorder written by Christopher Pittenger and published by Oxford University Press. This book was released on 2017 with total page 777 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obsessive-compulsive disorder (OCD) affects one person in 40 and can cause great suffering. This volume provides the first comprehensive summary of our understanding of this enigmatic condition, summarizing current work ranging from genetics and neurobiology through cognitive psychology, treatment, personal experiences, and societal implications.

Neuroanatomy: Text and Atlas

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Publisher : McGraw Hill Professional
ISBN 13 : 9780071381833
Total Pages : 566 pages
Book Rating : 4.3/5 (818 download)

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Book Synopsis Neuroanatomy: Text and Atlas by : John Harry Martin

Download or read book Neuroanatomy: Text and Atlas written by John Harry Martin and published by McGraw Hill Professional. This book was released on 2003-03-27 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: With over 400 illustrations, this thoroughly updated edition examines how parts of the nervous system work together to regulate body systems and produce behavior.

Pituitary Adenylate Cyclase-Activating Polypeptide

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9781402073069
Total Pages : 432 pages
Book Rating : 4.0/5 (73 download)

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Book Synopsis Pituitary Adenylate Cyclase-Activating Polypeptide by : Hubert Vaudry

Download or read book Pituitary Adenylate Cyclase-Activating Polypeptide written by Hubert Vaudry and published by Springer Science & Business Media. This book was released on 2003 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

Extrasynaptic GABAA Receptors

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Publisher : Springer
ISBN 13 : 149391426X
Total Pages : 301 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Extrasynaptic GABAA Receptors by : Adam C. Errington

Download or read book Extrasynaptic GABAA Receptors written by Adam C. Errington and published by Springer. This book was released on 2014-09-22 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABAA and GABAB receptors. Recently, a novel form of GABAA receptor-mediated inhibition, termed “tonic” inhibition, has been described. Whereas synaptic GABAA receptors underlie classical “phasic” GABAA receptor-mediated inhibition (inhibitory postsynaptic currents), tonic GABAA receptor-mediated inhibition results from the activation of extrasynaptic receptors by low concentrations of ambient GABA. Extrasynaptic GABAA receptors are composed of receptor subunits that convey biophysical properties ideally suited to the generation of persistent inhibition and are pharmacologically and functionally distinct from their synaptic counterparts. This book highlights ongoing work examining the properties of recombinant and native extrasynaptic GABAA receptors and their preferential targeting by endogenous and clinically relevant agents. In addition, it emphasizes the important role of extrasynaptic GABAA receptors in GABAergic inhibition throughout the CNS and identifies them as a major player in both physiological and pathophysiological processes.