Jasper's Basic Mechanisms of the Epilepsies

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Author :
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey Noebels

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Seizures and Epilepsy

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Publisher : Oxford University Press
ISBN 13 : 019532854X
Total Pages : 737 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Seizures and Epilepsy by : Jerome Engel Jr

Download or read book Seizures and Epilepsy written by Jerome Engel Jr and published by Oxford University Press. This book was released on 2013-01-31 with total page 737 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.

Astrocytes and Epilepsy

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Publisher : Academic Press
ISBN 13 : 0128026243
Total Pages : 395 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Astrocytes and Epilepsy by : Jacqueline A. Hubbard

Download or read book Astrocytes and Epilepsy written by Jacqueline A. Hubbard and published by Academic Press. This book was released on 2016-07-05 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy. - Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume - Provides a great resource on the field of astrocyte biology and astrocyte-neuron interactions - Details potential therapeutic targets, including chapters on gap junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation

The Neuroscience of Visual Hallucinations

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118731700
Total Pages : 373 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis The Neuroscience of Visual Hallucinations by : Daniel Collerton

Download or read book The Neuroscience of Visual Hallucinations written by Daniel Collerton and published by John Wiley & Sons. This book was released on 2015-02-23 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year, some two million people in the United Kingdom experience visual hallucinations. Infrequent, fleeting visual hallucinations, often around sleep, are a usual feature of life. In contrast, consistent, frequent, persistent hallucinations during waking are strongly associated with clinical disorders; in particular delirium, eye disease, psychosis, and dementia. Research interest in these disorders has driven a rapid expansion in investigatory techniques, new evidence, and explanatory models. In parallel, a move to generative models of normal visual function has resolved the theoretical tension between veridical and hallucinatory perceptions. From initial fragmented areas of investigation, the field has become increasingly coherent over the last decade. Controversies and gaps remain, but for the first time the shapes of possible unifying models are becoming clear, along with the techniques for testing these. This book provides a comprehensive survey of the neuroscience of visual hallucinations and the clinical techniques for testing these. It brings together the very latest evidence from cognitive neuropsychology, neuroimaging, neuropathology, and neuropharmacology, placing this within current models of visual perception. Leading researchers from a range of clinical and basic science areas describe visual hallucinations in their historical and scientific context, combining introductory information with up-to-date discoveries. They discuss results from the main investigatory techniques applied in a range of clinical disorders. The final section outlines future research directions investigating the potential for new understandings of veridical and hallucinatory perceptions, and for treatments of problematic hallucinations. Fully comprehensive, this is an essential reference for clinicians in the fields of the psychology and psychiatry of hallucinations, as well as for researchers in departments, research institutes and libraries. It has strong foundations in neuroscience, cognitive science, optometry, psychiatry, psychology, clinical medicine, and philosophy. With its lucid explanation and many illustrations, it is a clear resource for educators and advanced undergraduate and graduate students.

Mammalian Transient Receptor Potential (TRP) Cation Channels

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Author :
Publisher : Springer
ISBN 13 : 331905161X
Total Pages : 569 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Mammalian Transient Receptor Potential (TRP) Cation Channels by : Bernd Nilius

Download or read book Mammalian Transient Receptor Potential (TRP) Cation Channels written by Bernd Nilius and published by Springer. This book was released on 2014-06-24 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.

Handbook of Cerebrovascular Disease and Neurointerventional Technique

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Publisher : Springer Science & Business Media
ISBN 13 : 1617799467
Total Pages : 857 pages
Book Rating : 4.6/5 (177 download)

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Book Synopsis Handbook of Cerebrovascular Disease and Neurointerventional Technique by : Mark R. Harrigan

Download or read book Handbook of Cerebrovascular Disease and Neurointerventional Technique written by Mark R. Harrigan and published by Springer Science & Business Media. This book was released on 2012-10-03 with total page 857 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised and updated, the Handbook serves as a practical guide to endovascular methods and as a concise reference for neurovascular anatomy and published data about cerebrovascular disease from a neurointerventionalist’s perspective. Divided into three parts, the book covers: Fundamentals of neurovascular anatomy and basic angiographic techniques; Interventional Techniques and endovascular methods, along with useful device information and tips and tricks for daily practice; Specific Disease States, with essential clinical information about commonly encountered conditions. New features in the 2nd Edition include: Global Gems that illuminate aspects of the field outside the United States; Angio-anatomic and angio-pathologic image correlates; Newly released clinical study results influencing neurointerventional practice; Information on emerging technologies in this rapidly advancing field. The Handbook is a vital resource for all clinicians involved in neurointerventional practice, including radiologists, neurosurgeons, neurologists, cardiologists, and vascular surgeons.

Lishman's Organic Psychiatry

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Publisher : John Wiley & Sons
ISBN 13 : 0470675071
Total Pages : 972 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Lishman's Organic Psychiatry by : Daniel David

Download or read book Lishman's Organic Psychiatry written by Daniel David and published by John Wiley & Sons. This book was released on 2012-04-02 with total page 972 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this classic textbook has now been extensively revised by a team of five authors, yet it follows the tradition of the original single-authored book. It continues to provide a comprehensive review of the cognitive, emotional and behavioural consequences of cerebral disorders and their manifestations in clinical practice. Enabling clinicians to formulate incisive diagnoses and appropriate treatment strategies

The Neurobiology of Painting

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Author :
Publisher : Elsevier
ISBN 13 : 0080463614
Total Pages : 357 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis The Neurobiology of Painting by : Ronald J. Bradley

Download or read book The Neurobiology of Painting written by Ronald J. Bradley and published by Elsevier. This book was released on 2006-05-19 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents a basis for the interaction of the brain and nervous system with painting, music and literature, and a discussion of art from multiple facets – such as anatomy, migraine, illusion and evolutionary biology. The book explores several aspects of the neurobiology of painting, including evolutionary neurobiology, sensation vs. perception, the visual brain and how the mind works, and also explores the affects of brain disorders and trauma on artist, with a concluding chapter on Frida Kahlo and the spinal cord injury that influenced her painting.

Anthology of German Psychiatric Texts

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Publisher : John Wiley & Sons
ISBN 13 : 0470684348
Total Pages : 544 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Anthology of German Psychiatric Texts by : Henning Sass

Download or read book Anthology of German Psychiatric Texts written by Henning Sass and published by John Wiley & Sons. This book was released on 2009-06-22 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Descriptive Psychopathology

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Publisher : Cambridge University Press
ISBN 13 : 9780521713917
Total Pages : 498 pages
Book Rating : 4.7/5 (139 download)

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Book Synopsis Descriptive Psychopathology by : Michael Alan Taylor

Download or read book Descriptive Psychopathology written by Michael Alan Taylor and published by Cambridge University Press. This book was released on 2008-11-13 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to accurately describe and diagnose psychiatric illness, practitioners require in-depth knowledge of the signs and symptoms of behavioral disorders. Descriptive Psychopathology provides a broad review of the psychopathology of psychiatric illness, beyond the limitations of the DSM and ICD criteria. Beginning with a discussion of the background to psychiatric classification, the authors explore the problems and limitations of current diagnostic systems. The following chapters then present the principles of psychiatric examination and diagnosis, described with accompanying patient vignettes and summary tables, and related to different diagnostic concerns. A thought-provoking conclusion proposes a restructuring of psychiatric classification based on the psychopathology literature and its validating data. Written for psychiatry and neurology residents, as well as clinical psychologists, it is invaluable to anyone who accepts the responsibility for the care of patients with behavioral syndromes.

The Treatment of Epilepsy

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Publisher : John Wiley & Sons
ISBN 13 : 1118936981
Total Pages : 1072 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis The Treatment of Epilepsy by : Simon Shorvon

Download or read book The Treatment of Epilepsy written by Simon Shorvon and published by John Wiley & Sons. This book was released on 2015-09-15 with total page 1072 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly Commended at the British Medical Association Book Awards 2016 The Treatment of Epilepsy, fourth edition, is a comprehensive reference and clinical guide to the pharmacological, medical and surgical options available in the treatment of epilepsy. The text is compiled by a group of internationally renowned editors and contributors and is now in full color and extensively illustrated The first two sections cover the background to, and principles of, treatment in different clinical situations Section three comprises a series of systematic reviews of contemporary drug therapy, devoting one chapter to each anti-epileptic drug and covering all clinically-relevant aspects Section four focuses on the surgical options, devoting individual chapters to each of the modalities of presurgical assessment and to each surgical operation or approach This 4th edition is extensively revised incorporating the many recent developments in therapy, and comprises 81 chapters from world experts from 18 countries

A Dictionary of Hallucinations

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Publisher : Springer Science & Business Media
ISBN 13 : 1441912231
Total Pages : 553 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis A Dictionary of Hallucinations by : Jan Dirk Blom

Download or read book A Dictionary of Hallucinations written by Jan Dirk Blom and published by Springer Science & Business Media. This book was released on 2009-12-08 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Dictionary of Hallucinations is designed to serve as a reference manual for neuroscientists, psychiatrists, psychiatric residents, psychologists, neurologists, historians of psychiatry, general practitioners, and academics dealing professionally with concepts of hallucinations and other sensory deceptions.

The Madness of Fear

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Publisher : Oxford University Press
ISBN 13 : 0190881208
Total Pages : 225 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis The Madness of Fear by : Edward Shorter

Download or read book The Madness of Fear written by Edward Shorter and published by Oxford University Press. This book was released on 2018-06-27 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are the real disease entities in psychiatry? This is a question that has bedeviled the study of the mind for more than a century yet it is low on the research agenda of psychiatry. Basic science issues such as neuroimaging, neurochemistry, and genetics carry the day instead. There is nothing wrong with basic science research, but before studying the role of brain circuits or cerebral chemistry, shouldn't we be able to specify how the various diseases present clinically? Catatonia is a human behavioral syndrome that for almost a century was buried in the poorly designated psychiatric concept of schizophrenia. Its symptoms are well-know, and some of them are serious. Catatonic patients may die as their temperatures accelerate; they become dehydrated because they refuse to drink; they risk inanition because they refuse to eat or move. Autistic children with catatonia may hit themselves repeatedly in the head. We don't really know what catatonia is, in the sense that we know what pneumonia is. But we can identify it, and it is eminently treatable. Clinicians can make these patients better on a reliable basis. There are few other disease entities in psychiatry of which this is true. So why has there been so little psychiatric interest in catatonia? Why is it simply not on the radar of most clinicians? Catatonia actually occurs in a number of other medical illnesses as well, but it is certainly not on the radar of most internists or emergency physicians. In The Madness of Fear, Drs. Shorter and Fink seek to understand why this "vast field of ignorance" exists. In the history of catatonia, they see a remarkable story about how medicine flounders, and then seems to find its way. And it may help doctors, and the public, to recognize catatonia as one of the core illnesses in psychiatry.

Kaplan & Sadock's Study Guide and Self-Examination Review in Psychiatry

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451154453
Total Pages : 456 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Kaplan & Sadock's Study Guide and Self-Examination Review in Psychiatry by : Benjamin J. Sadock

Download or read book Kaplan & Sadock's Study Guide and Self-Examination Review in Psychiatry written by Benjamin J. Sadock and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kaplan & Sadock's Study Guide and Self-Examination Review in Psychiatry is a comprehensive review of the specialty and perfect for stand-alone review or as preparation for the PRITE in-service, ABPN Part I, and recertification examinations. The book contains more than 1,600 multiple-choice questions and answers, with explanatory discussions of correct and incorrect responses. Chapters parallel the essential corresponding chapters in Kaplan & Sadock's Synopsis of Psychiatry, a staple of psychiatry education around the globe. Terms and definitions are consistent with DSM-IV-TR and ICD-10.

The Neurobiological Basis of Suicide

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Publisher : CRC Press
ISBN 13 : 143983881X
Total Pages : 485 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis The Neurobiological Basis of Suicide by : Yogesh Dwivedi

Download or read book The Neurobiological Basis of Suicide written by Yogesh Dwivedi and published by CRC Press. This book was released on 2012-06-25 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Diagnosis, Management and Modeling of Neurodevelopmental Disorders

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Publisher : Academic Press
ISBN 13 : 0128179899
Total Pages : 628 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Diagnosis, Management and Modeling of Neurodevelopmental Disorders by : Colin R Martin

Download or read book Diagnosis, Management and Modeling of Neurodevelopmental Disorders written by Colin R Martin and published by Academic Press. This book was released on 2021-05-29 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosis, Management and Modeling of Neurodevelopmental Disorders: The Neuroscience of Development is a comprehensive reference on the diagnosis and management of neurodevelopment and associated disorders. The book discusses the mechanisms underlying neurological development and provides readers with a detailed introduction to the neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. In addition, the book also examines the pharmacological and non-pharmacological interventions of development-related conditions. - Provides the most comprehensive coverage of the broad range of topics relating to the neuroscience of aging - Features sections on the genetics that influences aging and diseases of aging - Contains an abstract, key facts, a mini dictionary of terms, and summary points in each chapter - Focuses on neurological diseases and conditions linked to aging, environmental factors and clinical recommendations - Includes more than 500 illustrations and tables

Mouse Brain Development

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Publisher : Springer Science & Business Media
ISBN 13 : 3540480021
Total Pages : 347 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Mouse Brain Development by : Andre M. Goffinet

Download or read book Mouse Brain Development written by Andre M. Goffinet and published by Springer Science & Business Media. This book was released on 2012-08-10 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of the molecular mechanisms involved in mammalian brain development remains limited. However, the last few years have wit nessed a quantum leap in our knowledge, due to technological improve ments, particularly in molecular genetics. Despite this progress, the available body of data remains mostly phenomenological and reveals very little about the grammar that organizes the molecular dictionary to articulate a pheno type. Nevertheless, the recent progress in genetics will allow us to contem plate, for the first time, the integration of observation into a coherent view of brain development. Clearly, this may be a major challenge for the next century, and arguably is the most important task of contemporary develop mental biology. The purpose of the present book is to provide an overview that syn thesizes up-to-date information on selected aspects of mouse brain devel opment. Given the format, it was not possible to cover all aspects of brain development, and many important subjects are missing. The selected themes are, to a certain extent, subjective and reflect the interests of the contributing authors. Examples of major themes that are not covered are peripheral nervous system development, including myelination, the development of the hippocampus and several other CNS structures, as well as the developmental function of some important morphoregulatory molecules.