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Author : Sune Nørhøj Jespersen
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (91 download)
Download or read book Diffusion Magnetic Resonance Imaging of Brain Tissue Microstructure written by Sune Nørhøj Jespersen and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Julien Valette
Publisher : Frontiers Media SA
ISBN 13 : 2889458415
Total Pages : 193 pages
Book Rating : 4.8/5 (894 download)
Download or read book Assessing Cellular Microstructure in Biological Tissues using In Vivo Diffusion-Weighted Magnetic Resonance written by Julien Valette and published by Frontiers Media SA. This book was released on 2019-05-16 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques have opened new doors for examining biological tissues in vivo. By combining sensitization to diffusion using magnetic field gradients with a variety of imaging and localization schemes, diffusion-weighted MRI and diffusion-weighted MRS allow investigating translational diffusion of endogenous molecules, such as water or metabolites, in biological tissues, most commonly the brain but also other organs such as the prostate. The typical voxel resolution of MRI or MRS is in the millimeter to centimeter range, much lower than the cellular scale. However, as molecules are typically diffusing over just a few µm during the duration of the measurement (the “diffusion time”) and encounter numerous biological membranes at these scales, the average cellular microstructure has a critical influence on the measured diffusion signal. Hence, diffusion-weighted MRI and diffusion-weighted MRS are sensitive to tissue microstructure at a scale well below the nominal imaging resolution. However, the connection between diffusion properties and tissue microstructure remains indirect, so any attempt to quantify microstructure will rely on modeling. The goal of this Research Topic was to gather experts in various acquisition and modeling strategies and show how these approaches, despite their own strengths and weaknesses, can yield unique information about cellular microstructure, and sometimes complement each other.
Download or read book Diffusion megnetic resonance imaging of brain tissue microstructure written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Evren Özarslan
Publisher : Springer Nature
ISBN 13 : 3030562158
Total Pages : 284 pages
Book Rating : 4.0/5 (35 download)
Download or read book Anisotropy Across Fields and Scales written by Evren Özarslan and published by Springer Nature. This book was released on 2021 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on processing, modeling, and visualization of anisotropy information, which are often addressed by employing sophisticated mathematical constructs such as tensors and other higher-order descriptors. It also discusses adaptations of such constructs to problems encountered in seemingly dissimilar areas of medical imaging, physical sciences, and engineering. Featuring original research contributions as well as insightful reviews for scientists interested in handling anisotropy information, it covers topics such as pertinent geometric and algebraic properties of tensors and tensor fields, challenges faced in processing and visualizing different types of data, statistical techniques for data processing, and specific applications like mapping white-matter fiber tracts in the brain. The book helps readers grasp the current challenges in the field and provides information on the techniques devised to address them. Further, it facilitates the transfer of knowledge between different disciplines in order to advance the research frontiers in these areas. This multidisciplinary book presents, in part, the outcomes of the seventh in a series of Dagstuhl seminars devoted to visualization and processing of tensor fields and higher-order descriptors, which was held in Dagstuhl, Germany, on October 28-November 2, 2018.
Author : Nicole Seiberlich
Publisher : Academic Press
ISBN 13 : 0128170581
Total Pages : 1094 pages
Book Rating : 4.1/5 (281 download)
Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Author : Moo K. Chung
Publisher : Cambridge University Press
ISBN 13 : 110718486X
Total Pages : 343 pages
Book Rating : 4.1/5 (71 download)
Download or read book Brain Network Analysis written by Moo K. Chung and published by Cambridge University Press. This book was released on 2019-06-27 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: This coherent mathematical and statistical approach aimed at graduate students incorporates regression and topology as well as graph theory.
Author : Heidi Johansen-Berg
Publisher : Academic Press
ISBN 13 : 0080878512
Total Pages : 507 pages
Book Rating : 4.0/5 (88 download)
Download or read book Diffusion MRI written by Heidi Johansen-Berg and published by Academic Press. This book was released on 2009-04-28 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion MRI is a magnetic resonance imaging (MRI) method that produces in vivo images of biological tissues weighted with the local microstructural characteristics of water diffusion, providing an effective means of visualizing functional connectivities in the nervous system. This book is the first comprehensive reference promoting the understanding of this rapidly evolving and powerful technology and providing the essential handbook for designing, analyzing or interpreting diffusion MR experiments.The book presents diffusion imaging in the context of well-established, classical experimental techniques, so that readers will be able to assess the scope and limitations of the new imaging technology with respect to techniques available previously. All chapters are written by leading international experts and cover methodology, validation of the imaging technology, application of diffusion imaging to the study of variation and development of normal brain anatomy, and disruption to the white matter in neurological disease or psychiatric disorder. • Discusses all aspects of a diffusion MRI study from acquisition, through analysis, to interpretation, providing an essential reference text for scientists designing or interpreting diffusion MR experiments• Practical advice on running an experiment• Full color throughout
Author : Susumu Mori
Publisher : Academic Press
ISBN 13 : 0123984076
Total Pages : 141 pages
Book Rating : 4.1/5 (239 download)
Download or read book Introduction to Diffusion Tensor Imaging written by Susumu Mori and published by Academic Press. This book was released on 2013-08-02 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concepts behind diffusion tensor imaging (DTI) are commonly difficult to grasp, even for magnetic resonance physicists. To make matters worse, a many more complex higher-order methods have been proposed over the last few years to overcome the now well-known deficiencies of DTI. In Introduction to Diffusion Tensor Imaging: And Higher Order Models, these concepts are explained through extensive use of illustrations rather than equations to help readers gain a more intuitive understanding of the inner workings of these techniques. Emphasis is placed on the interpretation of DTI images and tractography results, the design of experiments, and the types of application studies that can be undertaken. Diffusion MRI is a very active field of research, and theories and techniques are constantly evolving. To make sense of this constantly shifting landscape, there is a need for a textbook that explains the concepts behind how these techniques work in a way that is easy and intuitive to understand—Introduction to Diffusion Tensor Imaging fills this gap. Extensive use of illustrations to explain the concepts of diffusion tensor imaging and related methods Easy to understand, even without a background in physics Includes sections on image interpretation, experimental design, and applications Up-to-date information on more recent higher-order models, which are increasingly being used for clinical applications
Author : Nathan S. White
Publisher :
ISBN 13 :
Total Pages : 129 pages
Book Rating : 4.:/5 (525 download)
Download or read book Quantitative Diffusion Magnetic Resonance Imaging of the Brain written by Nathan S. White and published by . This book was released on 2010 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Owing to its exquisitely sensitive contrast mechanism, diffusion magnetic resonance imaging is a powerful non-invasive approach for studying the microstructural properties of the human brain in vivo. Magnetic resonance images are made sensitive to the microscopic displacements of water molecules that take place in brain tissue as part of the natural, physical diffusion process. Tissue water is used as an intrinsic probe, revealing important clues into the subtle architectural features of normal and pathologic brain tissue. Typical inferences include the intravoxel orientation distribution of neuronal fibers and changes in diffusion resulting from cell swelling in acute stroke. However, despite the many important advances made in the field of diffusion magnetic resonance imaging over the past decade, quantitative inference in the human brain remains somewhat limited due to the lack of direct quantitative validation against realistic biological architectures and practical limitations in data collection due to sub-optimal design parameters and artifacts caused by patient motion during scanning. In addition, current methods to resolve neuronal fiber orientations are unable to disambiguate fiber structures at different microscopic length (size) scales. In this dissertation I present a series of studies addressing each of these important limitations, starting with a general real-time image-based technique for motion correction in magnetic resonance images and ending with a series of studies on inferring complex fiber orientations from diffusion data, addressing issues such as quantitative histological validation, optimal acquisition, and improved multi-scale analysis.
Author : Ying Ding
Publisher : Open Dissertation Press
ISBN 13 : 9781361304884
Total Pages : pages
Book Rating : 4.3/5 (48 download)
Download or read book Magnetic Resonance Diffusion Characterization of Brain Diseases written by Ying Ding and published by Open Dissertation Press. This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Magnetic Resonance Diffusion Characterization of Brain Diseases" by 丁莹, Ying, Ding, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Magnetic resonance imaging (MRI) is a valuable imaging technique. It provides excellent soft tissue contrast and multi-parametric non-invasive imaging protocols. Among those various techniques, diffusion MRI measures the water diffusion properties of biological tissue. It is a useful tool in characterizing various brain tissue microstructures quantitatively. With its rapid development, it is emerging that subtle changes can be probed by diffusion tensor imaging (DTI) quantitation. The objectives of this doctoral work are to access the subtle microstructural alterations in rodent brains due to hemodynamic changes, fear conditioning and sleep deprivation using in vivo DTI. With the improved reproducibility and specificity achieved by using advanced post-processing and animal preparation procedures, in vivo DTI is expected to be useful to explore the underlying biological mechanisms for posttraumatic stress disorder and memory deficit following sleep loss in human. Firstly, as DTI could be influenced by the presence of water molecules in brain vasculature, for better understand the reproducibility and sensitivity of in vivo DTI measurements, conventional DTI protocol was applied to a well-controlled rat model of hypercapnia. Our data demonstrated that diffusivities increased in whole brain, gray and white matter regions in response to hypercapnia. These results indicate that in vivo DTI quantitation in brain can be interfered by vascular factors on the order of few percents. Cautions should be taken in designing and interpreting quantitative DTI studies as all DTI indices can be potentially confounded by physiologic conditions, cerebrovascular and hemodynamic characteristics. Secondly, recent DTI studies have shown detection of long-term neural plasticity weeks to months following relatively extensive periods of training in animals. However, rapid plasticity within a short period (24 hours) after learning is important for observing the time course of training-evoked changes and narrow down candidate mechanisms. Fear conditioning (FC), which typically occurs over a short timescale (in minutes), was selected as a paradigm for investigation. Using voxel-wise repeated measures analysis, FA was found to increase in amygdala and decrease in hippocampus 1-hour post-FC, and it reversed in both regions 1-day post-FC. Results indicate that DTI can detect rapid microstructural changes in brain regions known to mediate fear conditioning in vivo. DTI indices could be explored as a translational tool to capture potential early biological changes in individuals at risk for developing post-traumatic stress disorder. Thirdly, in vivo DTI was employed to access regional specific microstructural changes following rapid eye movement sleep deprivation (SD), and explore possible temporal differentiation of these changes. With voxel-base analysis, MD is found to decrease in post-SD time points in bilateral hippocampi and cerebral cortex. The distributions of these clusters exhibited differentiable layer specific patterns, which were pointing to dentate gyrus and CA1 layer in hippocampus, and parietal cortex and barrel field layers in cerebral cortex. Results indicate that in vivo DTI is capable to detect microstructural changes in specific layers and reveal temporal distinction between them. These specific layers are possibly more susceptible to sleep loss, and the temporal distinction of changes between these
Author : Wim Van Hecke
Publisher : Springer
ISBN 13 : 1493931180
Total Pages : 442 pages
Book Rating : 4.4/5 (939 download)
Download or read book Diffusion Tensor Imaging written by Wim Van Hecke and published by Springer. This book was released on 2015-12-14 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the practical aspects of diffusion tensor imaging (DTI), from understanding the basis of the technique through selection of the right protocols, trouble-shooting data quality, and analyzing DTI data optimally. DTI is a non-invasive magnetic resonance imaging (MRI) technique for visualizing and quantifying tissue microstructure based on diffusion. The book discusses the theoretical background underlying DTI and advanced techniques based on higher-order models and multi-shell diffusion imaging. It covers the practical implementation of DTI; derivation of information from DTI data; and a range of clinical applications, including neurosurgical planning and the assessment of brain tumors. Its practical utility is enhanced by decision schemes and a fully annotated DTI brain atlas, including color fractional anisotropy maps and 3D tractography reconstructions of major white matter fiber bundles. Featuring contributions from leading specialists in the field of DTI, Diffusion Tensor Imaging: A Practical Handbook is a valuable resource for radiologists, neuroradiologists, MRI technicians and clinicians.
Author : Michael E. Sughrue
Publisher : Academic Press
ISBN 13 : 0128136340
Total Pages : 256 pages
Book Rating : 4.1/5 (281 download)
Download or read book New Techniques for Management of ‘Inoperable’ Gliomas written by Michael E. Sughrue and published by Academic Press. This book was released on 2019-08-03 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients. Provides the first comprehensive book to discuss techniques for removing gliomas that are traditionally deemed ‘inoperable’ Presents a great reference tool that challenges stereotypical thinking by offering techniques by innovative surgeons Includes chapters that are organized by different glioma types and surgery/techniques
Author : Yoshiaki Toyama
Publisher : Springer Nature
ISBN 13 : 9811379084
Total Pages : 292 pages
Book Rating : 4.8/5 (113 download)
Download or read book Make Life Visible written by Yoshiaki Toyama and published by Springer Nature. This book was released on 2019-10-02 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.
Author : Daniel Topgaard
Publisher : Royal Society of Chemistry
ISBN 13 : 1788017269
Total Pages : 455 pages
Book Rating : 4.7/5 (88 download)
Download or read book Advanced Diffusion Encoding Methods in MRI written by Daniel Topgaard and published by Royal Society of Chemistry. This book was released on 2020-08-17 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: The medical MRI community is by far the largest user of diffusion NMR techniques and this book captures the current surge of methods and provides a primary source to aid adoption in this field. There is a trend to adapting the more advanced diffusion encoding sequences developed by NMR researchers within the fields of porous media, chemical engineering, and colloid science to medical research. Recently published papers indicate great potential for improved diagnosis of the numerous pathological conditions associated with changes of tissue microstructure that are invisible to conventional diffusion MRI. This book disseminates these recent developments to the wider community of MRI researchers and clinicians. The chapters cover the theoretical basis, hardware and pulse sequences, data analysis and validation, and recent applications aimed at promoting further growth in the field. This is a fast moving field and chapters are written by key MRI scientists that have contributed to the successful translation of the advanced diffusion NMR methods to the context of medical MRI, from global locations.
Author : 李鴻禧
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (891 download)
Download or read book In Vivo Diffusion Magnetic Resonance Imaging to Evaluate Microstructure of the Human Brain written by 李鴻禧 and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kei Yamada
Publisher : Elsevier Health Sciences
ISBN 13 : 0323759971
Total Pages : 161 pages
Book Rating : 4.3/5 (237 download)
Download or read book Advances in Diffusion-Weighted Imaging, An Issue of Magnetic Resonance Imaging Clinics of North America written by Kei Yamada and published by Elsevier Health Sciences. This book was released on 2021-05-05 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of MRI Clinics focuses on Advances in Diffusion-weighted Imaging and is edited by Dr. Kei Yamada. Articles will include: Technical Basics of Diffusion-weighted Imaging; Neurofluid as Assessed by Diffusion-weighted Imaging; Diffusion-weighted Imaging is the Key to Diagnoses; Diffusion-weighted Imaging of the Spinal Cord; Intracranial Abnormalities with Diffusion Restriction; Brain Anatomy by Diffusion-weighted Imaging; Measuring Perfusion: Intravoxel Incoherent Motion; Temperature Measurement by Diffusion-weighted Imaging; Diffusion-weighted Imaging at Ultra-high Field MRI; Diffusion-weighted Imaging for Radiomics; Diffusion Weighted Imaging for Infants; Diffusion-weighted Imaging of the Head and Neck (Including Temporal Bone); DTI, DKI and Q-space Imaging; and more!
Author : Lauren O'Donnell
Publisher : Springer
ISBN 13 : 3319111825
Total Pages : 216 pages
Book Rating : 4.3/5 (191 download)
Download or read book Computational Diffusion MRI written by Lauren O'Donnell and published by Springer. This book was released on 2015-02-17 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains papers presented at the 2014 MICCAI Workshop on Computational Diffusion MRI, CDMRI’14. Detailing new computational methods applied to diffusion magnetic resonance imaging data, it offers readers a snapshot of the current state of the art and covers a wide range of topics from fundamental theoretical work on mathematical modeling to the development and evaluation of robust algorithms and applications in neuroscientific studies and clinical practice. Inside, readers will find information on brain network analysis, mathematical modeling for clinical applications, tissue microstructure imaging, super-resolution methods, signal reconstruction, visualization, and more. Contributions include both careful mathematical derivations and a large number of rich full-color visualizations. Computational techniques are key to the continued success and development of diffusion MRI and to its widespread transfer into the clinic. This volume will offer a valuable starting point for anyone interested in learning computational diffusion MRI. It also offers new perspectives and insights on current research challenges for those currently in the field. The book will be of interest to researchers and practitioners in computer science, MR physics, and applied mathematics.
