Current Topics In Complement Ii

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Current Topics in Complement II

Author : John D. Lambris
Publisher : Springer Science & Business Media
ISBN 13 : 0387789529
Total Pages : 333 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Current Topics in Complement II by : John D. Lambris

Download or read book Current Topics in Complement II written by John D. Lambris and published by Springer Science & Business Media. This book was released on 2012-02-04 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complement has long been regarded as a pivotal effector arm of the innate immune response, eliciting important immunoregulatory functions in the context of inflammation and also serving as a vital link between the innate and adaptive immune response. In the post-genomic era, our knowledge of the innate immune system is enriched by findings that point to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or Inflammation. Several studies indicate that complement proteins exert functions that are either more complex than previously thought, or go well beyond the innate immune character of the system. The advent of high-throughput platforms for genome and proteome-wide profiling, together with the enormous amount of raw genetic information that has accumulated in the databases, have stirred new expectations in biomedical research. They have led complementologists to revisit established biological systems, such as the complement system, from a global and integrative perspective. Complement research is now faced with the challenge of trying to integrate isolated biochemical pathways into complex gene and protein regulatory circuits. In this respect, scientists from around the world convened at the Fourth Aegean Conferences Workshop on Complement Associated Diseases, Animal Models, and Therapeutics (June 10-15, 2007), to discuss recent advances in this fast evolving field. This volume represents a collection of topics on the “novel” functions of complement, patho-physiology, protein structures, design of complement inhibitors, and complement assays discussed during the conference.

Current Topics in Complement II

Author : John D. Lambris
Publisher : Springer
ISBN 13 : 9780387570549
Total Pages : 0 pages
Book Rating : 4.5/5 (75 download)

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Book Synopsis Current Topics in Complement II by : John D. Lambris

Download or read book Current Topics in Complement II written by John D. Lambris and published by Springer. This book was released on 2008-11-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complement has long been regarded as a pivotal effector arm of the innate immune response, eliciting important immunoregulatory functions in the context of inflammation and also serving as a vital link between the innate and adaptive immune response. In the post-genomic era, our knowledge of the innate immune system is enriched by findings that point to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or Inflammation. Several studies indicate that complement proteins exert functions that are either more complex than previously thought, or go well beyond the innate immune character of the system. The advent of high-throughput platforms for genome and proteome-wide profiling, together with the enormous amount of raw genetic information that has accumulated in the databases, have stirred new expectations in biomedical research. They have led complementologists to revisit established biological systems, such as the complement system, from a global and integrative perspective. Complement research is now faced with the challenge of trying to integrate isolated biochemical pathways into complex gene and protein regulatory circuits. In this respect, scientists from around the world convened at the Fourth Aegean Conferences Workshop on Complement Associated Diseases, Animal Models, and Therapeutics (June 10-15, 2007), to discuss recent advances in this fast evolving field. This volume represents a collection of topics on the “novel” functions of complement, patho-physiology, protein structures, design of complement inhibitors, and complement assays discussed during the conference.

Current Topics in Complement

Author : John D. Lambris
Publisher : Springer Science & Business Media
ISBN 13 : 038734134X
Total Pages : 423 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Current Topics in Complement by : John D. Lambris

Download or read book Current Topics in Complement written by John D. Lambris and published by Springer Science & Business Media. This book was released on 2007-01-26 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Third Aegean Conferences Workshop on Complement-Associated Diseases, Animal Models, and Therapeutics convened to discuss progress in complement research as it pertains to human disease pathogenesis and therapeutics. The rapid pace of research and new experimental approaches allow an integrated view of the in vivo biology of the complement system. This book collects writings on the functions of complement, pathophysiology, protein structures, design of complement inhibitors, and complement assays discussed at the conference.

The Complement System

Author : Mihaela Gadjeva
Publisher : Humana
ISBN 13 : 9781493963065
Total Pages : 0 pages
Book Rating : 4.9/5 (63 download)

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Book Synopsis The Complement System by : Mihaela Gadjeva

Download or read book The Complement System written by Mihaela Gadjeva and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complement Systems: Methods and Protocols is composed of 32 individual chapters that describe a variety of protocols to purify and analyze the activity of the individual complement components or pathways. It includes assays that describe detection of complement SNPs, clinical methods to evaluate complement system activation and data interpretation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Complement Systems: Methods and Protocols provides a collection of well-established “classical” assays and recently developed “new” assays to analyze the complement system activation will be useful to a wide audience of scientists.

The Complement FactsBook

Author : Scott R. Barnum
Publisher : Academic Press
ISBN 13 : 0080529550
Total Pages : 237 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Complement FactsBook by : Scott R. Barnum

Download or read book The Complement FactsBook written by Scott R. Barnum and published by Academic Press. This book was released on 1999-10-28 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Complement FactsBook contains entries on all components of the Complement System, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. The FactsBook also includes the cDNA sequences, marked with intron/exon boundaries, which will facilitate genetic studies. Includes the cDNA sequences, marked with intron/exon boundaries, facilitating genetic studies Presents detailed structural information including cDNA and gene structure for all proteins Introduces complement function, simply described for each function Data is as up-to-date as possible, including unpublished work from many contributors Incorporates domain structures diagrams, which beautifully illustrate the relationship between all the complement proteins, both within, and between, familiesEach chapter has been written by an expert in the field Data is as up-to-date as possible, including unpublished work from many contributors Entries provide information on: Alternative nomenclature, Physiochemical properties, Structure and function, Tissue distribution and regulation expression, Protein sequence/modules, Chromosomal location, Genomic structure, Database accession numbers, Deficiency and polymorphic variants, Key references

Complementary and Alternative Medicine in the United States

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309133424
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Complementary and Alternative Medicine in the United States by : Institute of Medicine

Download or read book Complementary and Alternative Medicine in the United States written by Institute of Medicine and published by National Academies Press. This book was released on 2005-04-13 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integration of complementary and alternative medicine therapies (CAM) with conventional medicine is occurring in hospitals and physicians offices, health maintenance organizations (HMOs) are covering CAM therapies, insurance coverage for CAM is increasing, and integrative medicine centers and clinics are being established, many with close ties to medical schools and teaching hospitals. In determining what care to provide, the goal should be comprehensive care that uses the best scientific evidence available regarding benefits and harm, encourages a focus on healing, recognizes the importance of compassion and caring, emphasizes the centrality of relationship-based care, encourages patients to share in decision making about therapeutic options, and promotes choices in care that can include complementary therapies where appropriate. Numerous approaches to delivering integrative medicine have evolved. Complementary and Alternative Medicine in the United States identifies an urgent need for health systems research that focuses on identifying the elements of these models, the outcomes of care delivered in these models, and whether these models are cost-effective when compared to conventional practice settings. It outlines areas of research in convention and CAM therapies, ways of integrating these therapies, development of curriculum that provides further education to health professionals, and an amendment of the Dietary Supplement Health and Education Act to improve quality, accurate labeling, research into use of supplements, incentives for privately funded research into their efficacy, and consumer protection against all potential hazards.

Cellular Transplantation

Author : Craig Halberstadt
Publisher : Elsevier
ISBN 13 : 0080469043
Total Pages : 696 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Cellular Transplantation by : Craig Halberstadt

Download or read book Cellular Transplantation written by Craig Halberstadt and published by Elsevier. This book was released on 2011-10-10 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: There have been tremendous strides in cellular transplantation in recent years, leading to accepted practice for the treatment of certain diseases, and use for many others in trial phases. The long history of cellular transplantation, or the transfer of cells from one organism or region of the body to another, has been revolutionized by advances in stem cell research, as well as developments in gene therapy. Cellular Transplants: From Lab to Clinic provides a thorough foundation of the basic science underpinning this exciting field, expert overviews of the state-of-the-art, and detailed description of clinical success stories to date, as well as insights into the road ahead. As highlighted by this timely and authoritative survey, scale-up technologies and whole organ transplantation are among the hurdles representing the next frontier. The contents are organized into four main sections, with the first covering basic biology, including transplant immunology, the use of immunosuppressive drugs, stem cell biology, and the development of donor animals for transplantation. The next part looks at peripheral and reconstructive applications, followed by a section devoted to transplantation for diseases of the central nervous system. The last part presents efforts to address the key challenges ahead, such as identifying novel transplantable cells and integrating biomaterials and nanotechnology with cell matrices. Provides detailed description of clinical trials in cell transplantation Review of current therapeutic approaches Coverage of the broad range of diseases addressed by cell therapeutics Discussion of stem cell biology and its role in transplantation

The Role of Complement in Health and Disease

Author : Maciej Cedzyński
Publisher : Frontiers Media SA
ISBN 13 : 2889631591
Total Pages : 631 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis The Role of Complement in Health and Disease by : Maciej Cedzyński

Download or read book The Role of Complement in Health and Disease written by Maciej Cedzyński and published by Frontiers Media SA. This book was released on 2019-11-18 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contemporary Practice in Clinical Chemistry

Author : William Clarke
Publisher : Academic Press
ISBN 13 : 0128158336
Total Pages : 1070 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Contemporary Practice in Clinical Chemistry by : William Clarke

Download or read book Contemporary Practice in Clinical Chemistry written by William Clarke and published by Academic Press. This book was released on 2020-06-11 with total page 1070 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary Practice in Clinical Chemistry, Fourth Edition, provides a clear and concise overview of important topics in the field. This new edition is useful for students, residents and fellows in clinical chemistry and pathology, presenting an introduction and overview of the field to assist readers as they in review and prepare for board certification examinations. For new medical technologists, the book provides context for understanding the clinical utility of tests that they perform or use in other areas in the clinical laboratory. For experienced laboratorians, this revision continues to provide an opportunity for exposure to more recent trends and developments in clinical chemistry. Includes enhanced illustration and new and revised color figures Provides improved self-assessment questions and end-of-chapter assessment questions

Molecular Mechanisms in Spermatogenesis

Author : C.Y. Cheng
Publisher : Springer Science & Business Media
ISBN 13 : 0387095977
Total Pages : 289 pages
Book Rating : 4.3/5 (87 download)

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Book Synopsis Molecular Mechanisms in Spermatogenesis by : C.Y. Cheng

Download or read book Molecular Mechanisms in Spermatogenesis written by C.Y. Cheng and published by Springer Science & Business Media. This book was released on 2009-10-24 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past thirty years, significant advances have been made in the field of reproductive biology in unlocking the molecular and biochemical events that regulate spermatogenesis in the mammalian testis. It was possible because of the unprecedented breakthroughs in molecular biology, cell biology, immunology, and biochemistry. In this book entitled, Molecular Mechanisms in Spermatogenesis, a collection of chapters has been included written by colleagues on the latest development in the field using genomic and proteomic approaches to study spermatogenesis, as well as different mechanisms and/or molecules including environmental toxicants and transcription factors that regulate and/or affect spermatogenesis. The book begins with a chapter that provides the basic concept of cellular regulation of spermatogenesis. A few chapters are also dedicated to some of the latest findings on the Sertoli cell cytoskeleton and other molecules (e.g., proteases, adhesion proteins) that regulate spermatogenesis. These chapters contain thought-provoking discussions and concepts which shall be welcomed by investigators in the field. It is obvious that many of these concepts will be updated and some may be amended in the years to come. However, they will serve as a guide and the basis for investigation by scientists in the field.

Current Topics in Anemia

Author : Jesmine Khan
Publisher : BoD – Books on Demand
ISBN 13 : 9535137743
Total Pages : 284 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Current Topics in Anemia by : Jesmine Khan

Download or read book Current Topics in Anemia written by Jesmine Khan and published by BoD – Books on Demand. This book was released on 2018-02-07 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with a very common condition, anemia, which might interest not only the physicians but also other healthcare professionals and researchers dealing with anemic patients. The objective of this book was to collect and compile up-to-date information from reputable researchers of different countries of the world to disseminate the latest information about the common types of anemia in some specific physiological and pathological conditions including pathophysiology and the use of algorithms as a tool to minimize the laboratory tests and accurate diagnosis of the underlying cause. In total, there are 13 chapters in this book where the authors shared their research findings and real-life experiences in managing their patients with anemia.

Physiology and Medicine of Hyperbaric Oxygen Therapy

Author : Tom S. Neuman
Publisher : Elsevier Health Sciences
ISBN 13 : 1416034064
Total Pages : 637 pages
Book Rating : 4.4/5 (16 download)

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Book Synopsis Physiology and Medicine of Hyperbaric Oxygen Therapy by : Tom S. Neuman

Download or read book Physiology and Medicine of Hyperbaric Oxygen Therapy written by Tom S. Neuman and published by Elsevier Health Sciences. This book was released on 2008-06-05 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by internationally recognized leaders in hyperbaric oxygen therapy (HBOT) research and practice, this exciting new book provides evidence-based, practical, useful information for anyone involved in HBOT. It outlines the physiologic principles that constitute the basis for understanding the clinical implications for treatment and describes recent advances and current research, along with new approaches to therapy. This book is an essential tool for anyone who cares for patients with difficult-to-heal wounds, wounds from radiation therapy, carbon monoxide poisoning, and more. Provides comprehensive coverage of pathophysiology and clinically relevant information so you can master the specialty. Covers the relevance of HBOT in caring for diverse populations including critical care patients, infants and pediatric patients, and divers. Features a section on the technical aspects of HBOT to provide insight into the technology and physics regarding HBO chambers. Presents evidence to support the effectiveness of HBOT as well as the possible side effects. Describes situations where HBOT would be effective through indication-specific chapters on chronic wounds, radiation and crush injuries, decompression sickness, and more.

The Control of Communicable Diseases

Author : American Public Health Association
Publisher :
ISBN 13 :
Total Pages : 100 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis The Control of Communicable Diseases by : American Public Health Association

Download or read book The Control of Communicable Diseases written by American Public Health Association and published by . This book was released on 1945 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Human Complement System in Health and Disease

Author : John E. Volanakis
Publisher : CRC Press
ISBN 13 : 9780824798987
Total Pages : 672 pages
Book Rating : 4.7/5 (989 download)

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Book Synopsis The Human Complement System in Health and Disease by : John E. Volanakis

Download or read book The Human Complement System in Health and Disease written by John E. Volanakis and published by CRC Press. This book was released on 1998-02-25 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative, single-source reference provides comprehensive examinations of the complement system-offering recent findings in basic science on the structure, biology, physiology, and pathophysiology of complement proteins and the latest therapeutic approaches towards the control of complement-mediated diseases. Written by over 40 international experts from North America, Europe, and Asia, The Human Complement System in Health and Disease describes the molecular architecture of the complement system details the structure of complement genes discusses gene organization as well as the topology and chemistry of ligand-binding sites and catalytic centers of complement proteins analyzes complement organization and activation, including phylogeny and the newly discovered lectin pathway elucidates the regulation of complement gene expression and the structure and function of bioactive peptides explicates opsonic and immunoregulatory properties of complement fragments, endothelial responses, and interactions with viruses and bacteria and more!

Neutralization of Animal Viruses

Author : Nigel J. Dimmock
Publisher : Springer
ISBN 13 : 9783642778513
Total Pages : 0 pages
Book Rating : 4.7/5 (785 download)

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Book Synopsis Neutralization of Animal Viruses by : Nigel J. Dimmock

Download or read book Neutralization of Animal Viruses written by Nigel J. Dimmock and published by Springer. This book was released on 2011-12-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding neutralization is particularly relevant to an appreciation of the interaction between a virus and its antibody-synthesizing host since it is likely that viruses and the antibody system have evolved in response to reciprocally imposed selective pressures. Neutralization of viruses which only infect non-antibody-synthesizing hosts, while of considerable interest from of points of view is de facto without any such evolutionary signifi a number cance. In this second category are viruses of plants, invertebrates, vertebrates below fish in the evolutionary scale which do not synthesize antibody and most bacteria. Viruses of organisms parasitic on or commensal with antibody synthesizing vertebrates, such as enteric bacteria, protozoa or metazoan parasites, will be in contac, with antibody at some stage of their existence, and arthropod-borne viruses which have a higher vertebrate as second host are obviously bona fide members of the first category. There is an urgent need to understand the principles by which antibodies inactivate virus infectivity since, at present, we are unable to rationally construct effective vaccines against new agents like the human immuno deficiency viruses or to improve existing vaccines. The intention of this volume is to comprehensively review neutralization and where possible to construct a unifying theory which can be tested by experimentation.

Janeway's Immunobiology

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

The Biomaterials: Silver Jubilee Compendium

Author : David F. Williams
Publisher : Elsevier
ISBN 13 : 0080528066
Total Pages : 257 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Biomaterials: Silver Jubilee Compendium by : David F. Williams

Download or read book The Biomaterials: Silver Jubilee Compendium written by David F. Williams and published by Elsevier. This book was released on 2011-07-28 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: The journal Biomaterials was launched in 1980. The subject of biomaterials science was then in its infancy, being largely cofined to the study of the characteristics of materials used for medical devices.Twenty-five years on, we can truly say that biomaterials science has matured at an incredible rate and now represents a formidable sector that bridges the materials sciences, advanced medical therapies, and molecular and cell sciences.This Silver Jubilee Compendium consists of reprinted versions of the top 25 papers, published during these 25 years, as judged by an international panel of biomaterials scientists.This book is published as a landmark in biomaterials science and it is to be hoped that it will serve as a stimulus to young biomaterials scientists of the early twenty-first century for their pioneering work of the future.