Controlling Blood Glucose Concentration of Diabetic Patients Using Fuzzy Logic Control

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ISBN 13 :
Total Pages : 146 pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Controlling Blood Glucose Concentration of Diabetic Patients Using Fuzzy Logic Control by : Joshua D. Avery

Download or read book Controlling Blood Glucose Concentration of Diabetic Patients Using Fuzzy Logic Control written by Joshua D. Avery and published by . This book was released on 2016 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been much advancement in the field of medicine over the course of human history, but especially in the last century. Many medicinal theories have come and gone with more accurate and up-to-date research. Today testing and validation of research is often done with computers and mathematical modeling. One of the common fields in medicine which uses similar computer simulation is insulin replacement therapy for diabetic patients. A diabetic patient lacks the capability of naturally producing insulin the human body needs to regulate blood sugar. The pancreas is responsible for producing insulin to counteract the constant fluctuations in blood sugar. Many factors such as eating, exercising and even sleeping will cause blood sugar levels to rise and fall. Without regular doses of insulin to regulate blood sugar, diabetic patients can experience health complications. Many methods of insulin replacement for diabetic patients have been used throughout the history of treating diabetes. The most innovative and current methods of insulin replacement today stems from the invention of the artificial pancreas. This thesis focuses on the design of a controller for the artificial pancreas with the goal of maximizing its effectiveness. A mathematical metabolic model of the human body, which is validated by the FDA to be used in nonhuman virtual trials, is used. With this model, the user is able to define a wide variety of parameters and most importantly design a controller to make the closed loop system work as effectively as possible. There are many methods that have been used to design a controller, For this thesis, the focus will be evaluating the use of Fuzzy Logic at the heart of the controller for the artificial pancreas. It is shown that with the combination of the mathematical model and the Fuzzy Logic controller, improved performance was achieved. Various implementations of Fuzzy Logic control are detailed and compared to other methods developed by other researchers. The results show Fuzzy Logic has the potential to be a very effective method to use for the control of an artificial pancreas.

Prediction Methods for Blood Glucose Concentration

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Publisher : Springer
ISBN 13 : 331925913X
Total Pages : 271 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Prediction Methods for Blood Glucose Concentration by : Harald Kirchsteiger

Download or read book Prediction Methods for Blood Glucose Concentration written by Harald Kirchsteiger and published by Springer. This book was released on 2015-11-24 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book tackles the problem of overshoot and undershoot in blood glucose levels caused by delay in the effects of carbohydrate consumption and insulin administration. The ideas presented here will be very important in maintaining the welfare of insulin-dependent diabetics and avoiding the damaging effects of unpredicted swings in blood glucose – accurate prediction enables the implementation of counter-measures. The glucose prediction algorithms described are also a key and critical ingredient of automated insulin delivery systems, the so-called “artificial pancreas”. The authors address the topic of blood-glucose prediction from medical, scientific and technological points of view. Simulation studies are utilized for complementary analysis but the primary focus of this book is on real applications, using clinical data from diabetic subjects. The text details the current state of the art by surveying prediction algorithms, and then moves beyond it with the most recent advances in data-based modeling of glucose metabolism. The topic of performance evaluation is discussed and the relationship of clinical and technological needs and goals examined with regard to their implications for medical devices employing prediction algorithms. Practical and theoretical questions associated with such devices and their solutions are highlighted. This book shows researchers interested in biomedical device technology and control researchers working with predictive algorithms how incorporation of predictive algorithms into the next generation of portable glucose measurement can make treatment of diabetes safer and more efficient.

Closed-Loop Control of Blood Glucose

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Publisher : Springer
ISBN 13 : 3540740317
Total Pages : 167 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Closed-Loop Control of Blood Glucose by : Frederick Chee

Download or read book Closed-Loop Control of Blood Glucose written by Frederick Chee and published by Springer. This book was released on 2007-10-24 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents closed-loop blood glucose control in a simple manner, which includes the hardware and "software" components that make up the control system. It provides examples on how mathematical models are formulated as well as the control algorithms that stem from mathematical exercises. The book also describes the basic physiology of blood glucose regulation during fasting and meal from a functional level.

FPGA Fuzzy (Pd & Pid) Controller Models for Insulin Pumps in Diabetes

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Publisher : LAP Lambert Academic Publishing
ISBN 13 : 9783659141287
Total Pages : 76 pages
Book Rating : 4.1/5 (412 download)

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Book Synopsis FPGA Fuzzy (Pd & Pid) Controller Models for Insulin Pumps in Diabetes by : Harikumar Rajaguru

Download or read book FPGA Fuzzy (Pd & Pid) Controller Models for Insulin Pumps in Diabetes written by Harikumar Rajaguru and published by LAP Lambert Academic Publishing. This book was released on 2012-06 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book emphasizes on a Field Programmable Gate Array (FPGA) Implementation of Fuzzy PD and PID Controller for biomedical application. A novel approach aims to identify and design a simple robust Fuzzy (PD and PID) Controller system with minimum number of fuzzy rules to deliver insulin from pumps as a single injection process for the diabetic patients. This controller is an automatic feedback control system in which the patient's blood glucose level is monitored from non-invasive Photo plethysmogram of a pulse oximeter (Photoglucometer) and insulin is infused with the change in the glucose level of the diabetic patient. This work was carried out in three phases like phase -I VLSI Design and simulation of Fuzzy PD controller were performed and analyzed. From the VLSI Simulation results FPGA Model was synthesized in the phase-II. During phase -III performance of the fuzzy PD Controller was evaluated. VLSI fuzzy system was simulated and analyzed then FPGA module was synthesized and implemented using VHDL.A part of this work was sponsored by IEEE Inc., (U.S.A) under scheme IEEE Student Enterprise Award 2007-2008 title FPGA Model of Fuzzy PD Controller for Insulin Pumps In Diabetes.

Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach

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Publisher : Academic Press
ISBN 13 : 0323907776
Total Pages : 164 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach by : Anirudh Nath

Download or read book Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach written by Anirudh Nath and published by Academic Press. This book was released on 2022-08-13 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI-Based Approach exposes readers to the various existing mathematical models that define the dynamics of glucose-insulin for Type 1 diabetes patients. After providing insights into the mathematical model of patients, the authors discuss the need and emergence of new control techniques that can lead to further development of an artificial pancreas. The book presents various nonlinear control techniques to address the challenges that Type 1 diabetic patients face in maintaining their blood glucose level in the safe range (70-180 mg/dl). The closed-loop solution provided by the artificial pancreas depends mainly on the effectiveness of the control algorithm, which acts as the brain of the system. APS control algorithms require a mathematical model of the gluco-regulatory system of the T1D patients for their design. Since the gluco-regulatory system is inherently nonlinear and largely affected by external disturbances and parametric uncertainty, developing an accurate model is very difficult. Presents control-oriented modeling of the gluco-regulatory system of Type 1 diabetic patients using input-output data Demonstrates the design of a robust insulin delivery mechanism utilizing state estimation information with parametric uncertainties and exogenous disturbance in the framework of Linear Matrix Inequality (LMI) Introduces readers to the relevance and effectiveness of powerful nonlinear controllers for the Artificial Pancreas Provides the first book on LMI-based nonlinear control techniques for the Artificial Pancreas

A Control Study Approach to Regulate Blood Glucose Level

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Publisher :
ISBN 13 :
Total Pages : 40 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis A Control Study Approach to Regulate Blood Glucose Level by : Pratik Mehta

Download or read book A Control Study Approach to Regulate Blood Glucose Level written by Pratik Mehta and published by . This book was released on 2018 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Instrumentation is an exciting field to discover and explore. Diabetes mellitus is one of the critical research areas which has been addressed for decades. The development of the constant glucose measuring devices and insulin pumps give an expectation for better well-being. The pancreas in the body plays a dynamic part in regulating the glucose level in blood. The function of the pancreas to produce insulin enzymes. The deficiency of the pancreas causes to rise in blood glucose level. Many research scientists are working on diagnosing and treating this diabetes mellitus disease. The mathematical model adopted in this work represents the dynamics of glucose and insulin. The name of model is extended Bergman Minimal Model. With this model, a closed loop feedback control system of blood glucose-insulin is developed to normalize the glucose level in blood. The developed system is implemented and analyzed with a software tool called MATLAB. The PID control and Fuzzy control methods are designed for exogenous insulin infusion pumps. These control methods are applied to the developed system to maintain the blood glucose level in desired range. Simulations shows that both designed control methods can keep the blood glucose level in desired range. However, the PID control method able to achieve the setpoint while the fuzzy control is never able to reach the setpoint value. With the PID control method, the output is oscillatory in nature to give blood glucose value before coming to the setpoint value. The fuzzy controller gives small overshoot in output but within the normal range.

Recent Advances in Operations Management Applications

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Publisher : Springer Nature
ISBN 13 : 9811670595
Total Pages : 424 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Recent Advances in Operations Management Applications by : Anish Sachdeva

Download or read book Recent Advances in Operations Management Applications written by Anish Sachdeva and published by Springer Nature. This book was released on 2022-02-28 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the select proceedings of the International Conference on Industrial and Manufacturing Systems (CIMS 2020). It presents the current scenarios and future advancements in the domain of industrial engineering under context of optimum value. Various topics covered include optimisation and its applicability in the various areas of industrial engineering like selection of designing parameters and, decisions related to conditions of optimum process/operation parameters, facilities planning and management, transportation and supply chain management, quality engineering, reliability and maintenance, system optimization, product design and development, human factors and ergonomics, project management, service system and service management, waste management, sustainable manufacturing and operations, systems design, lean manufacturing, and performance measurement. This book will be useful for the students, researchers and professionals working in the area of industrial and production engineering.

Theory and Applications of Non-integer Order Systems

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Publisher : Springer
ISBN 13 : 3319454749
Total Pages : 497 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Theory and Applications of Non-integer Order Systems by : Artur Babiarz

Download or read book Theory and Applications of Non-integer Order Systems written by Artur Babiarz and published by Springer. This book was released on 2016-09-15 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects papers from the 8th Conference on Non-Integer Order Calculus and Its Applications that have been held on September 20-21, 2016 in Zakopane, Poland. The preceding two conferences were held in Szczecin, Poland in 2015, and in Opole, Poland, in 2014. This conference provides a platform for academic exchange on the theory and application of fractional calculus between domestic and international universities, research institutes, corporate experts and scholars. The Proceedings of the 8th Conference on Non-Integer Order Calculus and Its Applications 2016 brings together rigorously reviewed contributions from leading international experts. The included papers cover novel various important aspects of mathematical foundations of fractional calculus, modeling and control of fractional systems as well as controllability, detectability, observability and stability problems for this systems.

Control Applications for Biomedical Engineering Systems

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Publisher : Academic Press
ISBN 13 : 0128174625
Total Pages : 476 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Control Applications for Biomedical Engineering Systems by : Ahmad Taher Azar

Download or read book Control Applications for Biomedical Engineering Systems written by Ahmad Taher Azar and published by Academic Press. This book was released on 2020-01-22 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Control Applications for Biomedical Engineering Systems presents different control engineering and modeling applications in the biomedical field. It is intended for senior undergraduate or graduate students in both control engineering and biomedical engineering programs. For control engineering students, it presents the application of various techniques already learned in theoretical lectures in the biomedical arena. For biomedical engineering students, it presents solutions to various problems in the field using methods commonly used by control engineers. Points out theoretical and practical issues to biomedical control systems Brings together solutions developed under different settings with specific attention to the validation of these tools in biomedical settings using real-life datasets and experiments Presents significant case studies on devices and applications

Fuzzy Logic And Soft Computing

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Publisher : World Scientific
ISBN 13 : 9814500089
Total Pages : 509 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Fuzzy Logic And Soft Computing by : Bernadette Bouchon-meunier

Download or read book Fuzzy Logic And Soft Computing written by Bernadette Bouchon-meunier and published by World Scientific. This book was released on 1995-09-15 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Soft computing is a new, emerging discipline rooted in a group of technologies that aim to exploit the tolerance for imprecision and uncertainty in achieving solutions to complex problems. The principal components of soft computing are fuzzy logic, neurocomputing, genetic algorithms and probabilistic reasoning.This volume is a collection of up-to-date articles giving a snapshot of the current state of the field. It covers the whole expanse, from theoretical foundations to applications. The contributors are among the world leaders in the field.

Type 1 Diabetes in Adults

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Publisher : Royal College of Physicians
ISBN 13 : 1860162282
Total Pages : 187 pages
Book Rating : 4.8/5 (61 download)

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Book Synopsis Type 1 Diabetes in Adults by : National Collaborating Centre for Chronic Conditions (Great Britain)

Download or read book Type 1 Diabetes in Adults written by National Collaborating Centre for Chronic Conditions (Great Britain) and published by Royal College of Physicians. This book was released on 2004 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microelectronic Design of Fuzzy Logic-Based Systems

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Publisher : CRC Press
ISBN 13 : 1482273861
Total Pages : 336 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Microelectronic Design of Fuzzy Logic-Based Systems by : Iluminada Baturone

Download or read book Microelectronic Design of Fuzzy Logic-Based Systems written by Iluminada Baturone and published by CRC Press. This book was released on 2018-10-08 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fuzzy logic has virtually exploded over the landscape of emerging technologies, becoming an integral part of myriad applications and a standard tool for engineers. Until recently, most of the attention and applications have centered on fuzzy systems implemented in software. But these systems are limited. Problems that require real-time operation, low area, or low power consumption demand hardware designed to the fuzzy paradigm - and engineers with the background and skills to design it. Microelectronic Design of Fuzzy Logic-Based Systems offers low-cost answers to issues that software cannot resolve. From the theoretical, architectural, and technological foundation to design tools and applications, it serves as your guide to effective hardware realizations of fuzzy logic. Review fuzzy logic theory and the basic issues of fuzzy sets, operators, and inference mechanisms Explore the trade-offs between efficient theoretical behavior and practical hardware realizations Discover the properties of the possible microelectronic realizations of fuzzy systems - conventional processors, fuzzy coprocessors, and fuzzy chips Investigate the design of fuzzy chips that implement the whole fuzzy inference method into silicon Analyze analog, digital, and mixed-signal techniques Reduce your design effort for fuzzy systems with CAD tools - learn the requirements they should meet and survey current environments. Put it all together - see examples and case studies illustrating how all of this is used to solve particular problems related to control and neuro-fuzzy applications

Control Theory in Biomedical Engineering

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Publisher : Academic Press
ISBN 13 : 0128226218
Total Pages : 396 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Control Theory in Biomedical Engineering by : Olfa Boubaker

Download or read book Control Theory in Biomedical Engineering written by Olfa Boubaker and published by Academic Press. This book was released on 2020-06-30 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Control Theory in Biomedical Engineering: Applications in Physiology and Medical Robotics highlights the importance of control theory and feedback control in our lives and explains how this theory is central to future medical developments. Control theory is fundamental for understanding feedback paths in physiological systems (endocrine system, immune system, neurological system) and a concept for building artificial organs. The book is suitable for graduate students and researchers in the control engineering and biomedical engineering fields, and medical students and practitioners seeking to enhance their understanding of physiological processes, medical robotics (legs, hands, knees), and controlling artificial devices (pacemakers, insulin injection devices). Control theory profoundly impacts the everyday lives of a large part of the human population including the disabled and the elderly who use assistive and rehabilitation robots for improving the quality of their lives and increasing their independence. Gives an overview of state-of-the-art control theory in physiology, emphasizing the importance of this theory in the medical field through concrete examples, e.g., endocrine, immune, and neurological systems Takes a comprehensive look at advances in medical robotics and rehabilitation devices and presents case studies focusing on their feedback control Presents the significance of control theory in the pervasiveness of medical robots in surgery, exploration, diagnosis, therapy, and rehabilitation

Quantitative Systems Pharmacology

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Publisher : Elsevier
ISBN 13 : 0444639675
Total Pages : 420 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Quantitative Systems Pharmacology by : Davide Manca

Download or read book Quantitative Systems Pharmacology written by Davide Manca and published by Elsevier. This book was released on 2018-07-18 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Systems Pharmacology: Models and Model-Based Systems with Applications, Volume 42, provides a quantitative approach to problem-solving that is targeted to engineers. The book gathers the contributions of doctors, pharmacists, biologists, and chemists who give key information on the elements needed to model a complex machine like the human body. It presents information on diagnoses, administration and release of therapeutics, distribution metabolism and excretion of drugs, compartmental pharmacokinetics, physiologically-based pharmacokinetics, pharmacodynamics, identifiability of models, numerical methods for models identification, design of experiments, in vitro and in vivo models, and more. As the pharma community is progressively acknowledging that a quantitative and systematic approach to drug administration, release, pharmacokinetics and pharmacodynamics is highly recommended to understand the mechanisms and effects of drugs, this book is a timely resource. Outlines a model-based approach (based on Process Systems Engineering-OSE and Computer Aided Process Engineering-CAPE) in quantitative pharmacology Explains how therapeutics work in the human body and how anatomy and physiology influences drug efficacy Discusses how drugs are driven to specific targets using nanoparticles Offers insight into how in vitro and in vivo experiments help understand the drug mechanism of action and optimize their performance Includes case studies showing the positive outcome of these methods in personalized therapies, therapeutic drug monitoring, clinical trials analysis and drug formulation

Point-of-care Glucose Detection for Diabetic Monitoring and Management

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Publisher : CRC Press
ISBN 13 : 1315349183
Total Pages : 249 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Point-of-care Glucose Detection for Diabetic Monitoring and Management by : Sandeep Kumar Vashist

Download or read book Point-of-care Glucose Detection for Diabetic Monitoring and Management written by Sandeep Kumar Vashist and published by CRC Press. This book was released on 2017-01-12 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book unravels the role of Point-of-Care (POC) glucose monitoring as an essential part of diabetes management. It provides the reader with an in-depth knowledge and understanding of diabetes management, including: the need for POC glucose monitoring the glucose detection technologies (invasive, noninvasive and continuous) being used in the POC devices the analytical performance, characteristics, pros and cons of the POC devices developed to date the importance and role of glycated hemoglobin (HbA1c) monitoring for diabetes management the various POC devices and analyzers for the determination of HbA1c. This is the first book to provide complete up-to-date information on POC glucose detection technologies and devices for diabetic monitoring and management. It will be an important reference for healthcare professionals, biomedical engineers, researchers, economists and policy makers. This book also serves as an asset and teaching aid for professionals and researchers in diabetic monitoring and management.

Machine Learning in Healthcare Informatics

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Publisher : Springer Science & Business Media
ISBN 13 : 3642400175
Total Pages : 334 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Machine Learning in Healthcare Informatics by : Sumeet Dua

Download or read book Machine Learning in Healthcare Informatics written by Sumeet Dua and published by Springer Science & Business Media. This book was released on 2013-12-09 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is a unique effort to represent a variety of techniques designed to represent, enhance, and empower multi-disciplinary and multi-institutional machine learning research in healthcare informatics. The book provides a unique compendium of current and emerging machine learning paradigms for healthcare informatics and reflects the diversity, complexity and the depth and breath of this multi-disciplinary area. The integrated, panoramic view of data and machine learning techniques can provide an opportunity for novel clinical insights and discoveries.

A CONTROLLER FOR BLOOD GLUCOSE REGULATION BASED ON MODULATION OF INSULIN SENSITIVITY IN PEOPLE WITH TYPE I DIABETES.

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis A CONTROLLER FOR BLOOD GLUCOSE REGULATION BASED ON MODULATION OF INSULIN SENSITIVITY IN PEOPLE WITH TYPE I DIABETES. by :

Download or read book A CONTROLLER FOR BLOOD GLUCOSE REGULATION BASED ON MODULATION OF INSULIN SENSITIVITY IN PEOPLE WITH TYPE I DIABETES. written by and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: BackgroundDespite new technology developed for diabetes management, glucose control remains suboptimal especially during meals. In recent years, bioelectronic medicine has shown promise for management of glucose fluctuations by controlling the insulin sensitivity (SI) through modulation of neural pathways. Within this context, in this work we present a proof-of-concept of the first closed-loop system that incorporates SI as an additional control variable for glucose regulation. MethodThe coordinated bi-hormonal bio-inspired controller (BiAP) for type 1 diabetes mellitus (T1DM) was extended by including a standard proportional-derivative (sPD) controller to determine the optimal SI from continuous blood glucose measurements. The tuning of the parameters of the resulting hybrid hormonal-insulin sensitivity glucose (InSiG) controller, and a comparison in performance with BiAP, were carried out on a virtual population of subjects with T1DM (n=20, 10 adults and 10 adolescents). A statistical analysis of the differences between controllers was performed using the parametric student paired t-test (u03b1 = 0.01). ResultsInSiG significantly increased the percentage of time glucose levels were within target (70-180 md/dL) to 99.4u00b11.0% in adults and 96.4u00b14.6% in adolescents (p