Computational Methods With Applications In Bioinformatics Analysis

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Publisher : World Scientific
ISBN 13 : 981320799X
Total Pages : 232 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Computational Methods With Applications In Bioinformatics Analysis by : Tsai Jeffrey J P

Download or read book Computational Methods With Applications In Bioinformatics Analysis written by Tsai Jeffrey J P and published by World Scientific. This book was released on 2017-06-09 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compendium contains 10 chapters written by world renowned researchers with expertise in semantic computing, genome sequence analysis, biomolecular interaction, time-series microarray analysis, and machine learning algorithms. The salient feature of this book is that it highlights eight types of computational techniques to tackle different biomedical applications. These techniques include unsupervised learning algorithms, principal component analysis, fuzzy integral, graph-based ensemble clustering method, semantic analysis, interolog approach, molecular simulations and enzyme kinetics. The unique volume will be a useful reference material and an inspirational read for advanced undergraduate and graduate students, computer scientists, computational biologists, bioinformatics and biomedical professionals.

Computational Methods in Molecular Biology

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Publisher : Elsevier
ISBN 13 : 9780080860930
Total Pages : 368 pages
Book Rating : 4.8/5 (69 download)

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Book Synopsis Computational Methods in Molecular Biology by : S.L. Salzberg

Download or read book Computational Methods in Molecular Biology written by S.L. Salzberg and published by Elsevier. This book was released on 1998-06-19 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational biology is a rapidly expanding field, and the number and variety of computational methods used for DNA and protein sequence analysis is growing every day. These algorithms are extremely valuable to biotechnology companies and to researchers and teachers in universities. This book explains the latest computer technology for analyzing DNA, RNA, and protein sequences. Clear and easy to follow, designed specifically for the non-computer scientist, it will help biologists make better choices on which algorithm to use. New techniques and demonstrations are elucidated, as are state-of-the-art problems, and more advanced material on the latest algorithms. The primary audience for this volume are molecular biologists working either in biotechnology companies or academic research environments, individual researchers and the institutions they work for, and students. Any biologist who relies on computers should want this book. A secondary audience will be computer scientists developing techniques with applications in biology. An excellent reference for leading techniques, it will also help introduce computer scientists to the biology problems. This is an outstanding work which will be ideal for the increasing number of scientists moving into computational biology.

Computational Text Analysis

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Publisher : OUP Oxford
ISBN 13 : 0191513776
Total Pages : 312 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Computational Text Analysis by : Soumya Raychaudhuri

Download or read book Computational Text Analysis written by Soumya Raychaudhuri and published by OUP Oxford. This book was released on 2006-01-26 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together the two disparate worlds of computational text analysis and biology and presents some of the latest methods and applications to proteomics, sequence analysis and gene expression data. Modern genomics generates large and comprehensive data sets but their interpretation requires an understanding of a vast number of genes, their complex functions, and interactions. Keeping up with the literature on a single gene is a challenge itself-for thousands of genes it is simply. impossible. Here, Soumya Raychaudhuri presents the techniques and algorithms needed to access and utilize the vast scientific text, i.e. methods that automatically read the literature on all the genes. Including background chapters on the necessary biology, statistics and genomics, in addition to practical examples of interpreting many different types of modern experiments, this book is ideal for students and researchers in computational biology, bioinformatics, genomics, statistics and computer science

Computational Methods for Next Generation Sequencing Data Analysis

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Publisher : John Wiley & Sons
ISBN 13 : 1118169484
Total Pages : 460 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Computational Methods for Next Generation Sequencing Data Analysis by : Ion Mandoiu

Download or read book Computational Methods for Next Generation Sequencing Data Analysis written by Ion Mandoiu and published by John Wiley & Sons. This book was released on 2016-10-03 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces readers to core algorithmic techniques for next-generation sequencing (NGS) data analysis and discusses a wide range of computational techniques and applications This book provides an in-depth survey of some of the recent developments in NGS and discusses mathematical and computational challenges in various application areas of NGS technologies. The 18 chapters featured in this book have been authored by bioinformatics experts and represent the latest work in leading labs actively contributing to the fast-growing field of NGS. The book is divided into four parts: Part I focuses on computing and experimental infrastructure for NGS analysis, including chapters on cloud computing, modular pipelines for metabolic pathway reconstruction, pooling strategies for massive viral sequencing, and high-fidelity sequencing protocols. Part II concentrates on analysis of DNA sequencing data, covering the classic scaffolding problem, detection of genomic variants, including insertions and deletions, and analysis of DNA methylation sequencing data. Part III is devoted to analysis of RNA-seq data. This part discusses algorithms and compares software tools for transcriptome assembly along with methods for detection of alternative splicing and tools for transcriptome quantification and differential expression analysis. Part IV explores computational tools for NGS applications in microbiomics, including a discussion on error correction of NGS reads from viral populations, methods for viral quasispecies reconstruction, and a survey of state-of-the-art methods and future trends in microbiome analysis. Computational Methods for Next Generation Sequencing Data Analysis: Reviews computational techniques such as new combinatorial optimization methods, data structures, high performance computing, machine learning, and inference algorithms Discusses the mathematical and computational challenges in NGS technologies Covers NGS error correction, de novo genome transcriptome assembly, variant detection from NGS reads, and more This text is a reference for biomedical professionals interested in expanding their knowledge of computational techniques for NGS data analysis. The book is also useful for graduate and post-graduate students in bioinformatics.

Mathematics of Bioinformatics

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118099524
Total Pages : 231 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Mathematics of Bioinformatics by : Matthew He

Download or read book Mathematics of Bioinformatics written by Matthew He and published by John Wiley & Sons. This book was released on 2011-03-16 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematics of Bioinformatics: Theory, Methods, and Applications provides a comprehensive format for connecting and integrating information derived from mathematical methods and applying it to the understanding of biological sequences, structures, and networks. Each chapter is divided into a number of sections based on the bioinformatics topics and related mathematical theory and methods. Each topic of the section is comprised of the following three parts: an introduction to the biological problems in bioinformatics; a presentation of relevant topics of mathematical theory and methods to the bioinformatics problems introduced in the first part; an integrative overview that draws the connections and interfaces between bioinformatics problems/issues and mathematical theory/methods/applications.

Kernel Methods in Computational Biology

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Publisher : MIT Press
ISBN 13 : 9780262195096
Total Pages : 428 pages
Book Rating : 4.1/5 (95 download)

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Book Synopsis Kernel Methods in Computational Biology by : Bernhard Schölkopf

Download or read book Kernel Methods in Computational Biology written by Bernhard Schölkopf and published by MIT Press. This book was released on 2004 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: A detailed overview of current research in kernel methods and their application to computational biology.

Computational Methods for Microbiome Analysis

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Publisher : Frontiers Media SA
ISBN 13 : 2889664376
Total Pages : 170 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Computational Methods for Microbiome Analysis by : Joao Carlos Setubal

Download or read book Computational Methods for Microbiome Analysis written by Joao Carlos Setubal and published by Frontiers Media SA. This book was released on 2021-02-02 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computational Genome Analysis

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Publisher : Springer Science & Business Media
ISBN 13 : 0387288074
Total Pages : 542 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Computational Genome Analysis by : Richard C. Deonier

Download or read book Computational Genome Analysis written by Richard C. Deonier and published by Springer Science & Business Media. This book was released on 2005-12-27 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the foundations of key problems in computational molecular biology and bioinformatics. It focuses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding these applications. The book features a free download of the R software statistics package and the text provides great crossover material that is interesting and accessible to students in biology, mathematics, statistics and computer science. More than 100 illustrations and diagrams reinforce concepts and present key results from the primary literature. Exercises are given at the end of chapters.

Computational Systems Bioinformatics - Methods And Biomedical Applications

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Publisher : World Scientific Publishing Company
ISBN 13 : 9813106999
Total Pages : 400 pages
Book Rating : 4.8/5 (131 download)

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Book Synopsis Computational Systems Bioinformatics - Methods And Biomedical Applications by : Wong Stephen Tin Chi

Download or read book Computational Systems Bioinformatics - Methods And Biomedical Applications written by Wong Stephen Tin Chi and published by World Scientific Publishing Company. This book was released on 2008-01-02 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational systems biology is a new and rapidly developing field of research, concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. By focusing on either information processing of biological data or on modeling physical and chemical processes of biosystems, and in combination with the recent breakthrough in deciphering the human genome, computational systems biology is guaranteed to play a central role in disease prediction and preventive medicine, gene technology and pharmaceuticals, and other biotechnology fields.This book begins by introducing the basic mathematical, statistical, and data mining principles of computational systems biology, and then presents bioinformatics technology in microarray and sequence analysis step-by-step. Offering an insightful look into the effectiveness of the systems approach in computational biology, it focuses on recurrent themes in bioinformatics, biomedical applications, and future directions for research.

Computational Methods in Biomedical Research

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Publisher : CRC Press
ISBN 13 : 9781420010923
Total Pages : 432 pages
Book Rating : 4.0/5 (19 download)

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Book Synopsis Computational Methods in Biomedical Research by : Ravindra Khattree

Download or read book Computational Methods in Biomedical Research written by Ravindra Khattree and published by CRC Press. This book was released on 2007-12-12 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuing advances in biomedical research and statistical methods call for a constant stream of updated, cohesive accounts of new developments so that the methodologies can be properly implemented in the biomedical field. Responding to this need, Computational Methods in Biomedical Research explores important current and emerging computational statistical methods that are used in biomedical research. Written by active researchers in the field, this authoritative collection covers a wide range of topics. It introduces each topic at a basic level, before moving on to more advanced discussions of applications. The book begins with microarray data analysis, machine learning techniques, and mass spectrometry-based protein profiling. It then uses state space models to predict US cancer mortality rates and provides an overview of the application of multistate models in analyzing multiple failure times. The book also describes various Bayesian techniques, the sequential monitoring of randomization tests, mixed-effects models, and the classification rules for repeated measures data. The volume concludes with estimation methods for analyzing longitudinal data. Supplying the knowledge necessary to perform sophisticated statistical analyses, this reference is a must-have for anyone involved in advanced biomedical and pharmaceutical research. It will help in the quest to identify potential new drugs for the treatment of a variety of diseases.

Algorithms in Computational Molecular Biology

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Publisher : John Wiley & Sons
ISBN 13 : 1118101987
Total Pages : 1027 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Algorithms in Computational Molecular Biology by : Mourad Elloumi

Download or read book Algorithms in Computational Molecular Biology written by Mourad Elloumi and published by John Wiley & Sons. This book was released on 2011-04-04 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the most comprehensive and up-to-date collection of information on the topic of computational molecular biology. Bringing the most recent research into the forefront of discussion, Algorithms in Computational Molecular Biology studies the most important and useful algorithms currently being used in the field, and provides related problems. It also succeeds where other titles have failed, in offering a wide range of information from the introductory fundamentals right up to the latest, most advanced levels of study.

Bioinformatics

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Publisher : Humana
ISBN 13 : 9781493982509
Total Pages : 0 pages
Book Rating : 4.9/5 (825 download)

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Book Synopsis Bioinformatics by : Jonathan M. Keith

Download or read book Bioinformatics written by Jonathan M. Keith and published by Humana. This book was released on 2018-07-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides updated and expanded chapters covering a broad sampling of useful and current methods in the rapidly developing and expanding field of bioinformatics. Bioinformatics, Volume II: Structure, Function, and Applications, Second Edition is comprised of three sections: Structure, Function, Pathways and Networks; Applications; and Computational Methods. The first section examines methodologies for understanding biological molecules as systems of interacting elements. The Applications section covers numerous applications of bioinformatics, focusing on analysis of genome-wide association data, computational diagnostic, and drug discovery. The final section describes four broadly applicable computational methods that are important to this field. These are: modeling and inference, clustering, parameterized algorithmics, and visualization. As a volume in the highly successful Methods in Molecular Biology series, chapters feature the kind of detailand expert implementation advice to ensure positive results. Comprehensive and practical, Bioinformatics, Volume II: Structure, Function, and Applications is an essential resource for graduate students, early career researchers, and others who are in the process of integrating new bioinformatics methods into their research.

2nd International Workshop on Practical Applications of Computational Biology and Bioinformatics (IWPACBB 2008)

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Publisher : Springer Science & Business Media
ISBN 13 : 354085861X
Total Pages : 265 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis 2nd International Workshop on Practical Applications of Computational Biology and Bioinformatics (IWPACBB 2008) by : Juan Manuel Corchado Rodríguez

Download or read book 2nd International Workshop on Practical Applications of Computational Biology and Bioinformatics (IWPACBB 2008) written by Juan Manuel Corchado Rodríguez and published by Springer Science & Business Media. This book was released on 2008-09-16 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: The success of Bioinformatics in recent years has been prompted by research in mole- lar biology and medicine in initiatives like the human genome project. The volume and diversification of data has increased so much that it is very hard if not impossible to analyze it by human experts. The analysis of this growing body of data, intensified by the development of a number of high-throughput experimental techniques that are generating the so called 'omics' data, has prompted for new computational methods. New global approaches, such as Systems Biology, have been emerging replacing the reductionist view that dominated biology research in the last decades, requiring the coordinated efforts of biological researchers with those related to data analysis, mathematical modelling and computer science. Computational methods have been helping in tasks related to knowledge discovery, modelling and optimization tasks. This workshop brings the opportunity to discuss applications of Bioinformatics and Computational Biology exploring the interactions between computer scientists, bio- gists and other scientific researchers. The IWPACBB technical program includes 29 papers (23 long papers and 6 short papers) selected from a submission pool of 51 papers, from 9 different countries. We thank the excellent work of the local organization members and also from the members of the Program Committee for their excellent reviewing work. October 2008 Juan M. Corchado Juan F. De Paz Miguel P. Rocha Florentino Fernández Riverola Organization

Algorithmic Aspects of Bioinformatics

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Publisher : Springer Science & Business Media
ISBN 13 : 354071913X
Total Pages : 396 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Algorithmic Aspects of Bioinformatics by : Hans-Joachim Böckenhauer

Download or read book Algorithmic Aspects of Bioinformatics written by Hans-Joachim Böckenhauer and published by Springer Science & Business Media. This book was released on 2007-06-06 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces some key problems in bioinformatics, discusses the models used to formally describe these problems, and analyzes the algorithmic approaches used to solve them. After introducing the basics of molecular biology and algorithmics, Part I explains string algorithms and alignments; Part II details the field of physical mapping and DNA sequencing; and Part III examines the application of algorithmics to the analysis of biological data. Exciting application examples include predicting the spatial structure of proteins, and computing haplotypes from genotype data. Figures, chapter summaries, detailed derivations, and examples, are provided.

Essential Numerical Computer Methods

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Publisher : Academic Press
ISBN 13 : 9780123849984
Total Pages : 616 pages
Book Rating : 4.8/5 (499 download)

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Book Synopsis Essential Numerical Computer Methods by : Michael L. Johnson

Download or read book Essential Numerical Computer Methods written by Michael L. Johnson and published by Academic Press. This book was released on 2010-11-25 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of computers and computational methods has become ubiquitous in biological and biomedical research. During the last 2 decades most basic algorithms have not changed, but what has is the huge increase in computer speed and ease of use, along with the corresponding orders of magnitude decrease in cost. A general perception exists that the only applications of computers and computer methods in biological and biomedical research are either basic statistical analysis or the searching of DNA sequence data bases. While these are important applications they only scratch the surface of the current and potential applications of computers and computer methods in biomedical research. The various chapters within this volume include a wide variety of applications that extend far beyond this limited perception. As part of the Reliable Lab Solutions series, Essential Numerical Computer Methods brings together chapters from volumes 210, 240, 321, 383, 384, 454, and 467 of Methods in Enzymology. These chapters provide a general progression from basic numerical methods to more specific biochemical and biomedical applications. The various chapters within this volume include a wide variety of applications that extend far beyond this limited perception As part of the Reliable Lab Solutions series, Essential Numerical Computer Methods brings together chapters from volumes 210, 240, 321, 383, 384, 454, and 467 of Methods in Enzymology These chapters provide a general progression from basic numerical methods to more specific biochemical and biomedical applications

Evolving Connectionist Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 1846283477
Total Pages : 465 pages
Book Rating : 4.8/5 (462 download)

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Book Synopsis Evolving Connectionist Systems by : Nikola K. Kasabov

Download or read book Evolving Connectionist Systems written by Nikola K. Kasabov and published by Springer Science & Business Media. This book was released on 2007-08-23 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of the must-read work in the field presents generic computational models and techniques that can be used for the development of evolving, adaptive modeling systems, as well as new trends including computational neuro-genetic modeling and quantum information processing related to evolving systems. New applications, such as autonomous robots, adaptive artificial life systems and adaptive decision support systems are also covered.

Bioinformatics Algorithms

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Publisher : John Wiley & Sons
ISBN 13 : 0470097736
Total Pages : 528 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Bioinformatics Algorithms by : Ion Mandoiu

Download or read book Bioinformatics Algorithms written by Ion Mandoiu and published by John Wiley & Sons. This book was released on 2008-02-25 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents algorithmic techniques for solving problems in bioinformatics, including applications that shed new light on molecular biology This book introduces algorithmic techniques in bioinformatics, emphasizing their application to solving novel problems in post-genomic molecular biology. Beginning with a thought-provoking discussion on the role of algorithms in twenty-first-century bioinformatics education, Bioinformatics Algorithms covers: General algorithmic techniques, including dynamic programming, graph-theoretical methods, hidden Markov models, the fast Fourier transform, seeding, and approximation algorithms Algorithms and tools for genome and sequence analysis, including formal and approximate models for gene clusters, advanced algorithms for non-overlapping local alignments and genome tilings, multiplex PCR primer set selection, and sequence/network motif finding Microarray design and analysis, including algorithms for microarray physical design, missing value imputation, and meta-analysis of gene expression data Algorithmic issues arising in the analysis of genetic variation across human population, including computational inference of haplotypes from genotype data and disease association search in case/control epidemiologic studies Algorithmic approaches in structural and systems biology, including topological and structural classification in biochemistry, and prediction of protein-protein and domain-domain interactions Each chapter begins with a self-contained introduction to a computational problem; continues with a brief review of the existing literature on the subject and an in-depth description of recent algorithmic and methodological developments; and concludes with a brief experimental study and a discussion of open research challenges. This clear and approachable presentation makes the book appropriate for researchers, practitioners, and graduate students alike.