Characterization of Protein Phosphorylation by Nanoflow HPLC-microElectrospray Ionization Mass Spectrometry

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ISBN 13 :
Total Pages : 344 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Characterization of Protein Phosphorylation by Nanoflow HPLC-microElectrospray Ionization Mass Spectrometry by : Melanie Joy Schroeder

Download or read book Characterization of Protein Phosphorylation by Nanoflow HPLC-microElectrospray Ionization Mass Spectrometry written by Melanie Joy Schroeder and published by . This book was released on 2005 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dissertation Abstracts International

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ISBN 13 :
Total Pages : 794 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Dissertation Abstracts International by :

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2005 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein Phosphorylation and Differential Analysis

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ISBN 13 :
Total Pages : 338 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Protein Phosphorylation and Differential Analysis by : Mark David Platt

Download or read book Protein Phosphorylation and Differential Analysis written by Mark David Platt and published by . This book was released on 2004 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Analysis of Proteins and Peptides by Mass Spectrometry

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ISBN 13 :
Total Pages : 304 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis The Analysis of Proteins and Peptides by Mass Spectrometry by : Anthony Andrew High

Download or read book The Analysis of Proteins and Peptides by Mass Spectrometry written by Anthony Andrew High and published by . This book was released on 2003 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Enrichment and Analysis of Phosphorylated Peptides by Immobilized Metal Affinity Chromatography and Nanoflow-HPLC/microelectrospray Ionization/tandem Mass Spectrometry

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ISBN 13 :
Total Pages : 288 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Enrichment and Analysis of Phosphorylated Peptides by Immobilized Metal Affinity Chromatography and Nanoflow-HPLC/microelectrospray Ionization/tandem Mass Spectrometry by : Scott Benjamin Ficarro

Download or read book Enrichment and Analysis of Phosphorylated Peptides by Immobilized Metal Affinity Chromatography and Nanoflow-HPLC/microelectrospray Ionization/tandem Mass Spectrometry written by Scott Benjamin Ficarro and published by . This book was released on 2002 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Identification of Biologically Relevant Peptides by Nanoflow HPLC MicroElectrospray Ionization Mass Spectrometry

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ISBN 13 :
Total Pages : 260 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Identification of Biologically Relevant Peptides by Nanoflow HPLC MicroElectrospray Ionization Mass Spectrometry by : Jennifer Ann Caldwell

Download or read book Identification of Biologically Relevant Peptides by Nanoflow HPLC MicroElectrospray Ionization Mass Spectrometry written by Jennifer Ann Caldwell and published by . This book was released on 2000 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Index Medicus

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ISBN 13 :
Total Pages : 1568 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 1568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Spermatology

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Publisher : Society of Reproduction and Fe
ISBN 13 :
Total Pages : 560 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Spermatology by : Eduardo R. S. Roldan

Download or read book Spermatology written by Eduardo R. S. Roldan and published by Society of Reproduction and Fe. This book was released on 2007 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reveals the enormous potential that the study of spermatozoa has to improve our understanding of basic questions about evolution and about cellular function, and to develop new ways of manipulating sperm cells for applied purposes.

Directory of Graduate Research

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ISBN 13 :
Total Pages : 1846 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Directory of Graduate Research by :

Download or read book Directory of Graduate Research written by and published by . This book was released on 2001 with total page 1846 pages. Available in PDF, EPUB and Kindle. Book excerpt: Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.

Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis

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Publisher : Elsevier
ISBN 13 : 0444635734
Total Pages : 526 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis by :

Download or read book Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis written by and published by Elsevier. This book was released on 2016-06-02 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis deals with the use of high-resolution mass spectrometry (MS) in the analysis of small organic molecules. Over the past few years, time-of-flight (ToF) and Orbitrap MS have both experienced tremendous growth in a great number of analytical sectors and are now well established in many laboratories where high requirements are placed on analytical performance. This book gives a head-to-head comparison of these two technologies that compete directly with each other. As users with hands-on experience in both techniques, the authors provide a balanced description of the strengths and weaknesses of both techniques. In the vast majority of cases, ToF-MS and Orbitrap-MS have been used for qualitative purposes, mainly identification of discrete molecular entities such as drug metabolites or transformation products of environmental contaminants. This paradigm is now changing as quantitative capabilities are increasingly being explored, as are non-target approaches for unbiased broad-scope screening. In view of the continuous innovation of high-resolution MS instrument manufacturers in designing and developing more powerful machines, technological advances in both hardware and software are considerable, with many novel applications. This book summarizes and analyzes these trends. The compilation of selected examples from diverse analytical fields will allow the readers to discover not only the potential of high-resolution MS in their sector, but also shows advances in other fields that rely on hi-res MS. - Provides comprehensive coverage of applications of time-of-flight and orbitrap mass spectrometry in environmental, food, doping, and forensic analysis - Explores a variety of specialized techniques, giving a balanced description of the strengths and weaknesses of each - Presents a general overview of imaging techniques within analysis

Fundamentals of Contemporary Mass Spectrometry

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Publisher : John Wiley & Sons
ISBN 13 : 0470118482
Total Pages : 512 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Fundamentals of Contemporary Mass Spectrometry by : Chhabil Dass

Download or read book Fundamentals of Contemporary Mass Spectrometry written by Chhabil Dass and published by John Wiley & Sons. This book was released on 2007-05-11 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern mass spectrometry - the instrumentation and applications in diverse fields Mass spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an integral part of proteomics and drug discovery process. Fundamentals of Contemporary Mass Spectrometry gives readers a concise and authoritative overview of modern mass spectrometry instrumentation, techniques, and applications, including the latest developments. After an introduction to the history of mass spectrometry and the basic underlying concepts, it covers: Instrumentation, including modes of ionization, condensed phase ionization techniques, mass analysis and ion detection, tandem mass spectrometry, and hyphenated separation techniques Organic and inorganic mass spectrometry Biological mass spectrometry, including the analysis of proteins and peptides, oligosaccharides, lipids, oligonucleotides, and other biological materials Applications to quantitative analysis Based on proven teaching principles, each chapter is complete with a concise overview, highlighted key points, practice exercises, and references to additional resources. Hints and solutions to the exercises are provided in an appendix. To facilitate learning and improve problem-solving skills, several worked-out examples are included. This is a great textbook for graduate students in chemistry, and a robust, practical resource for researchers and scientists, professors, laboratory managers, technicians, and others. It gives scientists in diverse disciplines a practical foundation in modern mass spectrometry.

Acceleration and Improvement of Protein Identification by Mass Spectrometry

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Publisher : Springer Science & Business Media
ISBN 13 : 9781402033186
Total Pages : 324 pages
Book Rating : 4.0/5 (331 download)

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Book Synopsis Acceleration and Improvement of Protein Identification by Mass Spectrometry by : Willy Vincent Bienvenut

Download or read book Acceleration and Improvement of Protein Identification by Mass Spectrometry written by Willy Vincent Bienvenut and published by Springer Science & Business Media. This book was released on 2005-04-19 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: At present where protein identification and characterisation using mass spectrometry is a method of choice, this book is presenting a review of basic proteomic techniques. The second part of the book is related to the novel high throughput protein identification technique called the 'molecular scanner'. Several protein identification techniques are described, especially the peptide mass fingerprint with MALDI-MS based method. E.g. ionisation process, matrix available, signal reproducibility and suppression effect, as well as date treatment for protein identification using bioinformatics tools.

Proteomic and Metabolomic Approaches to Biomarker Discovery

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Publisher : Academic Press
ISBN 13 : 0123947952
Total Pages : 489 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Proteomic and Metabolomic Approaches to Biomarker Discovery by : Haleem J. Issaq

Download or read book Proteomic and Metabolomic Approaches to Biomarker Discovery written by Haleem J. Issaq and published by Academic Press. This book was released on 2013-05-20 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research. - Describes the use of biomarkers to reduce clinical errors in research - Includes techniques from a range of biomarker discoveries - Covers all steps involved in biomarker discovery, from study design to study execution

Modern Proteomics – Sample Preparation, Analysis and Practical Applications

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Publisher : Springer
ISBN 13 : 3319414488
Total Pages : 525 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Modern Proteomics – Sample Preparation, Analysis and Practical Applications by : Hamid Mirzaei

Download or read book Modern Proteomics – Sample Preparation, Analysis and Practical Applications written by Hamid Mirzaei and published by Springer. This book was released on 2016-12-14 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume serves as a proteomics reference manual, describing experimental design and execution. The book also shows a large number of examples as to what can be achieved using proteomics techniques. As a relatively young area of scientific research, the breadth and depth of the current state of the art in proteomics might not be obvious to all potential users. There are various books and review articles that cover certain aspects of proteomics but they often lack technical details. Subject specific literature also lacks the broad overviews that are needed to design an experiment in which all steps are compatible and coherent. The objective of this book was to create a proteomics manual to provide scientists who are not experts in the field with an overview of: 1. The types of samples can be analyzed by mass spectrometry for proteomics analysis. 2. Ways to convert biological or ecological samples to analytes ready for mass spectral analysis. 3. Ways to reduce the complexity of the proteome to achieve better coverage of the constituent proteins. 4. How various mass spectrometers work and different ways they can be used for proteomics analysis 5. The various platforms that are available for proteomics data analysis 6. The various applications of proteomics technologies in biological and medical sciences This book should appeal to anyone with an interest in proteomics technologies, proteomics related bioinformatics and proteomics data generation and interpretation. With the broad setup and chapters written by experts in the field, there is information that is valuable for students as well as for researchers who are looking for a hands on introduction into the strengths, weaknesses and opportunities of proteomics.

Membrane Proteomics

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Publisher : Humana Press
ISBN 13 : 9781617378898
Total Pages : 0 pages
Book Rating : 4.3/5 (788 download)

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Book Synopsis Membrane Proteomics by : Matthew J. Peirce

Download or read book Membrane Proteomics written by Matthew J. Peirce and published by Humana Press. This book was released on 2010-11-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The membranes surrounding cells and organelles constitute their interface with the local environment. The functions of membrane proteins include cell/cell and cell/extracellular matrix recognition, the reception and transduction of extracellular signals, and the tra- port of proteins, solutes and water molecules. Abnormal membrane protein expression has profound biological effects and may, for example, underlie phenotypic and functional differences between normal and tumour cells. Moreover the accessibility, particularly of plasma proteins traversing the plasma membrane of cells, makes them of particular ut- ity to the therapeutic intervention in disease. Indeed, it is estimated that of all currently licensed pharmaceuticals, approximately 70% target proteins resident in the plasma m- brane. In theory, unbiased technologies such as proteomics have the power to de?ne patterns of membrane protein expression characteristic of distinct states of cellular development, differentiation or disease, and thereby identify novel markers of, or targets for intervention in, disease. However, although about 25% of open reading frames in fully sequenced genomes are estimated to encode integral membrane proteins, global analysis of membrane protein expression has proved problematic. Membrane protein analysis poses unique challenges at the level of extraction, solubilization, and separation in particular, and to a lesser extent of identi?cation and quantitation. These challenges have, however, fostered creativity, in- vation, and technical advances, many of which are brought together in Membrane P- teomics.

Capillary Electrophoresis of Proteins and Peptides

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Publisher : Springer Science & Business Media
ISBN 13 : 159259798X
Total Pages : 340 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Capillary Electrophoresis of Proteins and Peptides by : Mark A. Strege

Download or read book Capillary Electrophoresis of Proteins and Peptides written by Mark A. Strege and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the more than 20 years that have followed the beginnings of capillary electrophoresis (CE), its application to the analysis of proteins and peptides has continued to be reliable, versatile, and productive. Over time, CE has matured to become a superb complement to HLPC, and in many cases has also evolved as an automated and quantitative replacement for conventional slab gel electrophoresis methods such as SDS-PAGE and isoelectric focusing. Within Capillary Electrophoresis of Proteins and Peptides, we have assembled contributions from researchers who are applying state-of-the-art CE for protein and peptide analysis, including topics that we believe are of great potential both in the present and for the future. In comparison to traditional separation methods, CE represents a miniaturized analysis technique (especially in its microchip-based format) that is highly dependent upon the basic fundamentals of effective sample recovery and high sensitivity detection. With these issues in mind, Chapters 1–4 describe recently developed approaches for both capillary coatings and analyte detection via laser-induced fluorescence. Since the discipline of biotechnology has established itself as a primary platform for the application of CE to the analysis of proteins and peptides, Chapters 5–7 demonstrate a variety of examples of the specific techniques that have been applied for the development of biopharmaceuticals and their commercialization. The methods covered here include also the analysis of oligosaccharides from glycoproteins.

Proteomics in Practice

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Publisher : John Wiley & Sons
ISBN 13 : 3527622306
Total Pages : 502 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Proteomics in Practice by : Reiner Westermeier

Download or read book Proteomics in Practice written by Reiner Westermeier and published by John Wiley & Sons. This book was released on 2008-09-08 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Still the only concise practical guide to laboratory experiments in proteomics, this new edition now also covers DIGE technology and liquid-chromatography, while the troubleshooting section has been considerably extended. Adopting a practical approach, the authors present the relevant techniques and explain the route to successful experimental design and optimal method selection. They cover such electrophoretic techniques as isoelectric focusing, SDS page, 2-D page, and DIGE, as well as liquid-chromatography techniques, such as ion exchange, affinity chromatography and reversed-phase HPLC. Mass-spectrometric techniques include MALDI, ESI, and FT ICR. Generously illustrated, partly in color, the book also features updates of protocols as well as animations illustrating crucial methodological steps on a companion website.