Cerebral Microcirculation

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The Cerebral Circulation

Author : Marilyn J. Cipolla
Publisher : Biota Publishing
ISBN 13 : 1615047239
Total Pages : 82 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Cerebral Circulation by : Marilyn J. Cipolla

Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.

The Cerebral Microvasculature

Author : Howard M. Eisenberg
Publisher : Springer Science & Business Media
ISBN 13 : 1468437526
Total Pages : 340 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis The Cerebral Microvasculature by : Howard M. Eisenberg

Download or read book The Cerebral Microvasculature written by Howard M. Eisenberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: As traced by Uichael Bradbury in his recently published monograph, The Concept of a BZood-Brain Barrier, the idea of a scientific challenge is just about as old as the twentieth century. Curiously, it remains undefined. Is it a structure or structures as some use the term, or is it a reciprocal per meability, a force-flow relationship, as do others, or is it a group of processes, some more specialized than others? Depend ing upon the observer, the method, and what is observed, it seems to be each of these or all. This Symposium takes as its focus of interest the micro vasculature of the brain and includes considerations of blood flow, the properties of vessel walls and the control of flow and permeability. In addition perturbations that change the characteristics of the flow of materials are given attention. By changing the usual focus of interest, the organizers, Drs. Suddith and Eisenberg, have given a fresh outlook to the subject and now, by publication of the Proceedings, have arranged for wide availability of these interesting papers. Keasley Welch v PREFACE A symposium on the cerebral microvasculature and its function in the blood-brain barrier was held at The University of Texas Medical Branch, Galveston, in the summer of 1979. Investigators from the United States and Europe met to discuss their recent work.

Brain Disorders in Critical Illness

Author : Robert D. Stevens
Publisher : Cambridge University Press
ISBN 13 : 1107434424
Total Pages : 457 pages
Book Rating : 4.1/5 (74 download)

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Book Synopsis Brain Disorders in Critical Illness by : Robert D. Stevens

Download or read book Brain Disorders in Critical Illness written by Robert D. Stevens and published by Cambridge University Press. This book was released on 2013-09-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.

PanVascular Medicine

Author : Peter Lanzer
Publisher : Springer
ISBN 13 : 9783642370779
Total Pages : 5004 pages
Book Rating : 4.3/5 (77 download)

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Book Synopsis PanVascular Medicine by : Peter Lanzer

Download or read book PanVascular Medicine written by Peter Lanzer and published by Springer. This book was released on 2015-03-30 with total page 5004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular management and care has become a truly multidisciplinary enterprise as the number of specialists involved in the treatment of patients with vascular diseases has steadily increased. While in the past, treatments were delivered by individual specialists, in the twenty-first century a team approach is without doubt the most effective strategy. In order to promote professional excellence in this dynamic and rapidly evolving field, a shared knowledge base and interdisciplinary standards need to be established. Pan Vascular Medicine, 2nd edition has been designed to offer such an interdisciplinary platform, providing vascular specialists with state-of-the art descriptive and procedural knowledge. Basic science, diagnostics, and therapy are all comprehensively covered. In a series of succinct, clearly written chapters, renowned specialists introduce and comment on the current international guidelines and present up-to-date reviews of all aspects of vascular care.

Cerebral Microcirculation

Author : Frithjof Hammersen
Publisher :
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cerebral Microcirculation by : Frithjof Hammersen

Download or read book Cerebral Microcirculation written by Frithjof Hammersen and published by . This book was released on 1990 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gupta and Gelb's Essentials of Neuroanesthesia and Neurointensive Care

Author : Arun Gupta
Publisher : Cambridge University Press
ISBN 13 : 1316602524
Total Pages : 427 pages
Book Rating : 4.3/5 (166 download)

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Book Synopsis Gupta and Gelb's Essentials of Neuroanesthesia and Neurointensive Care by : Arun Gupta

Download or read book Gupta and Gelb's Essentials of Neuroanesthesia and Neurointensive Care written by Arun Gupta and published by Cambridge University Press. This book was released on 2018-06-21 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition presents core clinical neuroanesthesia and neurointensive care knowledge in a practical, user-friendly format.

Cerebral Microcirculation and Metabolism

Author : Jorge Cervós-Navarro
Publisher : Raven Press (ID)
ISBN 13 :
Total Pages : 510 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Cerebral Microcirculation and Metabolism by : Jorge Cervós-Navarro

Download or read book Cerebral Microcirculation and Metabolism written by Jorge Cervós-Navarro and published by Raven Press (ID). This book was released on 1981 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Regulation of Tissue Oxygenation, Second Edition

Author : Roland N. Pittman
Publisher : Biota Publishing
ISBN 13 : 1615047212
Total Pages : 117 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Regulation of Tissue Oxygenation, Second Edition by : Roland N. Pittman

Download or read book Regulation of Tissue Oxygenation, Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Pathology of Cerebral Microcirculation

Author : Jorge Cervós-Navarro
Publisher :
ISBN 13 :
Total Pages : 530 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pathology of Cerebral Microcirculation by : Jorge Cervós-Navarro

Download or read book Pathology of Cerebral Microcirculation written by Jorge Cervós-Navarro and published by . This book was released on 1974 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Pathology of cerebral microcirculation".

Cerebral Small Vessel Disease

Author : Leonardo Pantoni
Publisher : Cambridge University Press
ISBN 13 : 1107031664
Total Pages : 375 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Cerebral Small Vessel Disease by : Leonardo Pantoni

Download or read book Cerebral Small Vessel Disease written by Leonardo Pantoni and published by Cambridge University Press. This book was released on 2014-05 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.

Brain Aging

Author : David R. Riddle
Publisher : CRC Press
ISBN 13 : 1420005529
Total Pages : 413 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Brain Aging by : David R. Riddle

Download or read book Brain Aging written by David R. Riddle and published by CRC Press. This book was released on 2007-04-19 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

Bioinformatics and Biomedical Engineering

Author : Ignacio Rojas
Publisher : Springer
ISBN 13 : 3030179354
Total Pages : 605 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Bioinformatics and Biomedical Engineering by : Ignacio Rojas

Download or read book Bioinformatics and Biomedical Engineering written by Ignacio Rojas and published by Springer. This book was released on 2019-04-30 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set LNBI 11465 and LNBI 11466 constitutes the proceedings of the 7th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2019, held in Granada, Spain, in May 2019. The total of 97 papers presented in the proceedings, was carefully reviewed and selected from 301 submissions. The papers are organized in topical sections as follows: Part I: High-throughput genomics: bioinformatics tools and medical applications; omics data acquisition, processing, and analysis; bioinformatics approaches for analyzing cancer sequencing data; next generation sequencing and sequence analysis; structural bioinformatics and function; telemedicine for smart homes and remote monitoring; clustering and analysis of biological sequences with optimization algorithms; and computational approaches for drug repurposing and personalized medicine. Part II: Bioinformatics for healthcare and diseases; computational genomics/proteomics; computational systems for modelling biological processes; biomedical engineering; biomedical image analysis; and biomedicine and e-health.

Medical Imaging

Author :
Publisher :
ISBN 13 :
Total Pages : 706 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Imaging by :

Download or read book Medical Imaging written by and published by . This book was released on 2003 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Microcirculation in Cardiovascular Diseases

Author : Enrico Agabiti-Rosei
Publisher : Springer Nature
ISBN 13 : 3030478017
Total Pages : 215 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Microcirculation in Cardiovascular Diseases by : Enrico Agabiti-Rosei

Download or read book Microcirculation in Cardiovascular Diseases written by Enrico Agabiti-Rosei and published by Springer Nature. This book was released on 2020-10-03 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognostic role of changes in small resistance artery structure, the possibility of preventing or regressing such alterations with appropriate treatment, and the potential clinical advantages of such intervention. A number of innovative areas of research are considered, including the role of the immune system, inflammation and oxidative stress in the development of microvascular alterations. Lastly, it examines the availability of recent non-invasive methods for the evaluation of small resistance artery morphology in the retina, which in the near future may provide a useful tool for the stratification of cardiovascular risk and even for clinical decisions regarding drug treatment, thus providing physicians with a clinically relevant instrument for improving and optimizing the management of hypertensive and diabetic patients. The book provides valuable, clinically relevant information for specialists (cardiology, internal medicine, and endocrinology) and general practitioners, and also offers novel and stimulating data to basic and clinical researchers.

Encyclopedia of Cardiovascular Research and Medicine

Author :
Publisher : Elsevier
ISBN 13 : 012805154X
Total Pages : 2854 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Encyclopedia of Cardiovascular Research and Medicine by :

Download or read book Encyclopedia of Cardiovascular Research and Medicine written by and published by Elsevier. This book was released on 2017-11-27 with total page 2854 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Cardiovascular Research and Medicine, Four Volume Set offers researchers over 200 articles covering every aspect of cardiovascular research and medicine, including fully annotated figures, abundant color illustrations and links to supplementary datasets and references. With contributions from top experts in the field, this book is the most reputable and easily searchable resource of cardiovascular-focused basic and translational content for students, researchers, clinicians and teaching faculty across the biomedical and medical sciences. The panel of authors chosen from an international board of leading scholars renders the text trustworthy, contemporary and representative of the global scientific expertise in these domains. The book's thematic structuring of sections and in-depth breakdown of topics encourages user-friendly, easily searchable chapters. Cross-references to related articles and links to further reading and references will further guide readers to a full understanding of the topics under discussion. Readers will find an unparalleled, one-stop resource exploring all major aspects of cardiovascular research and medicine. Presents comprehensive coverage of every aspect of cardiovascular medicine and research Offers readers a broad, interdisciplinary overview of the concepts in cardiovascular research and medicine with applications across biomedical research Includes reputable, foundational content on genetics, cancer, immunology, cell biology and molecular biology Provides a multi-media enriched color-illustrated text with high quality images, graphs and tables.

Inflammation and the Microcirculation

Author : D. Neil Granger
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041656
Total Pages : 99 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Inflammation and the Microcirculation by : D. Neil Granger

Download or read book Inflammation and the Microcirculation written by D. Neil Granger and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References

Neurosurgical Operative Atlas: Vascular Neurosurgery

Author : R. Loch Macdonald
Publisher : Thieme
ISBN 13 : 1604069309
Total Pages : 891 pages
Book Rating : 4.6/5 (4 download)

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Book Synopsis Neurosurgical Operative Atlas: Vascular Neurosurgery by : R. Loch Macdonald

Download or read book Neurosurgical Operative Atlas: Vascular Neurosurgery written by R. Loch Macdonald and published by Thieme. This book was released on 2018-11-14 with total page 891 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art neurovascular surgery atlas from internationally renowned neurosurgeon R. Loch Macdonald Neurosurgical Operative Atlas: Vascular Neurosurgery, Third Edition, by R. Loch Macdonald and expert contributors, reflects the latest advances in endoscopic, endovascular, microsurgical, and bypass techniques used in the treatment of cerebrovascular disease. The entire atlas has been streamlined and updated with new content, including 38 videos that complement the concise step-by-step guidance in the text. The book begins with five chapters on vascular and microsurgical instrumentation and equipment, clipping versus coiling, aneurysm surgery techniques, the pterional approach, and minimally invasive approaches. Disease and procedure-specific chapters are organized by three sections: aneurysms and subarachnoid hemorrhage, vascular malformations, and ischemic and other cerebrovascular disease. Every chapter includes salient tips on patient selection and procedural indications, preoperative information and tests, patient positioning, operative nuances, and postoperative complications. Key Highlights Nearly 300 high-quality color illustrations detail impacted anatomy and procedures The latest techniques for treating a full spectrum of aneurysms, such as ophthalmic segment, supraclinoid internal carotid artery, middle and anterior cerebral artery, basilar and posterior cerebral artery, and others Treatment of vascular abnormalities including arteriovenous malformations, superficial and brainstem cavernous malformations, arteriovenous fistulae, Moyamoya disease, and more Neurosurgical residents will benefit from the firsthand knowledge shared by international masters, while veteran neurosurgeons will glean invaluable insights on cutting-edge endovascular techniques to enhance clinical practice.