Cellular Signal Processing

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Publisher : Garland Science
ISBN 13 : 1351677225
Total Pages : 640 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Cellular Signal Processing by : Friedrich Marks

Download or read book Cellular Signal Processing written by Friedrich Marks and published by Garland Science. This book was released on 2017-05-17 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.

Handbook of Cell Signaling

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Publisher : Academic Press
ISBN 13 : 0080920918
Total Pages : 3048 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Handbook of Cell Signaling by : Ralph A. Bradshaw

Download or read book Handbook of Cell Signaling written by Ralph A. Bradshaw and published by Academic Press. This book was released on 2009-11-03 with total page 3048 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. Contains over 350 chapters of comprehensive coverage on cell signaling Includes discussion on topics from ligand/receptor interactions to organ/organism responses Provides user-friendly, well-illustrated, reputable content by experts in the field

Introduction to Cellular Signal Transduction

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Publisher : Springer Science & Business Media
ISBN 13 : 9780817639822
Total Pages : 352 pages
Book Rating : 4.6/5 (398 download)

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Book Synopsis Introduction to Cellular Signal Transduction by : Ari Sitaramayya

Download or read book Introduction to Cellular Signal Transduction written by Ari Sitaramayya and published by Springer Science & Business Media. This book was released on 1999 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mechanism of information transfer between cells is the subject of this text. In the past, aspects of this field were the domain of different disciplines, including endocrinology, neurochemistry, and pharmacology. However, in recent years, signal transduction has emerged as an independent discipline.

Signal Processing for 5G

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Publisher : John Wiley & Sons
ISBN 13 : 1119116465
Total Pages : 611 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Signal Processing for 5G by : Fa-Long Luo

Download or read book Signal Processing for 5G written by Fa-Long Luo and published by John Wiley & Sons. This book was released on 2016-10-17 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and invaluable guide to 5G technology, implementation and practice in one single volume. For all things 5G, this book is a must-read. Signal processing techniques have played the most important role in wireless communications since the second generation of cellular systems. It is anticipated that new techniques employed in 5G wireless networks will not only improve peak service rates significantly, but also enhance capacity, coverage, reliability , low-latency, efficiency, flexibility, compatibility and convergence to meet the increasing demands imposed by applications such as big data, cloud service, machine-to-machine (M2M) and mission-critical communications. This book is a comprehensive and detailed guide to all signal processing techniques employed in 5G wireless networks. Uniquely organized into four categories, New Modulation and Coding, New Spatial Processing, New Spectrum Opportunities and New System-level Enabling Technologies, it covers everything from network architecture, physical-layer (down-link and up-link), protocols and air interface, to cell acquisition, scheduling and rate adaption, access procedures and relaying to spectrum allocations. All technology aspects and major roadmaps of global 5G standard development and deployments are included in the book. Key Features: Offers step-by-step guidance on bringing 5G technology into practice, by applying algorithms and design methodology to real-time circuit implementation, taking into account rapidly growing applications that have multi-standards and multi-systems. Addresses spatial signal processing for 5G, in particular massive multiple-input multiple-output (massive-MIMO), FD-MIMO and 3D-MIMO along with orbital angular momentum multiplexing, 3D beamforming and diversity. Provides detailed algorithms and implementations, and compares all multicarrier modulation and multiple access schemes that offer superior data transmission performance including FBMC, GFDM, F-OFDM, UFMC, SEFDM, FTN, MUSA, SCMA and NOMA. Demonstrates the translation of signal processing theories into practical solutions for new spectrum opportunities in terms of millimeter wave, full-duplex transmission and license assisted access. Presents well-designed implementation examples, from individual function block to system level for effective and accurate learning. Covers signal processing aspects of emerging system and network architectures, including ultra-dense networks (UDN), software-defined networks (SDN), device-to-device (D2D) communications and cloud radio access network (C-RAN).

Wireless Communications

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Publisher : Prentice Hall
ISBN 13 : 9780136203452
Total Pages : 0 pages
Book Rating : 4.2/5 (34 download)

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Book Synopsis Wireless Communications by : H. Vincent Poor

Download or read book Wireless Communications written by H. Vincent Poor and published by Prentice Hall. This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete guide to the state-of-the-art in signal processing for wireless communications. Complete coverage is given of data compression, channel coding, modulator/demodulator design, receiver and transmitter design, and antenna design.

Cell Signaling

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Publisher : Taylor & Francis
ISBN 13 : 1317573625
Total Pages : 412 pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis Cell Signaling by : Wendell Lim

Download or read book Cell Signaling written by Wendell Lim and published by Taylor & Francis. This book was released on 2014-06-16 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Signaling presents the principles and components that underlie all known signaling processes. It provides undergraduate and graduate students the conceptual tools needed to make sense of the dizzying array of pathways used by the cell to communicate. By emphasizing the common design principles, components, and logic that drives all signa

Genomic Signal Processing and Statistics

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Publisher : Hindawi Publishing Corporation
ISBN 13 : 9775945070
Total Pages : 456 pages
Book Rating : 4.7/5 (759 download)

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Book Synopsis Genomic Signal Processing and Statistics by : Edward R. Dougherty

Download or read book Genomic Signal Processing and Statistics written by Edward R. Dougherty and published by Hindawi Publishing Corporation. This book was released on 2005 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in genomic studies have stimulated synergetic research and development in many cross-disciplinary areas. Processing the vast genomic data, especially the recent large-scale microarray gene expression data, to reveal the complex biological functionality, represents enormous challenges to signal processing and statistics. This perspective naturally leads to a new field, genomic signal processing (GSP), which studies the processing of genomic signals by integrating the theory of signal processing and statistics. Written by an international, interdisciplinary team of authors, this invaluable edited volume is accessible to students just entering this emergent field, and to researchers, both in academia and in industry, in the fields of molecular biology, engineering, statistics, and signal processing. The book provides tutorial-level overviews and addresses the specific needs of genomic signal processing students and researchers as a reference book. The book aims to address current genomic challenges by exploiting potential synergies between genomics, signal processing, and statistics, with special emphasis on signal processing and statistical tools for structural and functional understanding of genomic data. The first part of this book provides a brief history of genomic research and a background introduction from both biological and signal-processing/statistical perspectives, so that readers can easily follow the material presented in the rest of the book. In what follows, overviews of state-of-the-art techniques are provided. We start with a chapter on sequence analysis, and follow with chapters on feature selection, classification, and clustering of microarray data. We then discuss the modeling, analysis, and simulation of biological regulatory networks, especially gene regulatory networks based on Boolean and Bayesian approaches. Visualization and compression of gene data, and supercomputer implementation of genomic signal processing systems are also treated. Finally, we discuss systems biology and medical applications of genomic research as well as the future trends in genomic signal processing and statistics research.

Cellular Signal Transduction in Toxicology and Pharmacology

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Publisher : John Wiley & Sons
ISBN 13 : 1119060265
Total Pages : 336 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Cellular Signal Transduction in Toxicology and Pharmacology by : Jonathan W. Boyd

Download or read book Cellular Signal Transduction in Toxicology and Pharmacology written by Jonathan W. Boyd and published by John Wiley & Sons. This book was released on 2019-04-16 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets. Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research Includes detailed presentations of study methodology and data collection, analysis, and interpretation Discusses tools like experimental design, sample handling, analytical measurement techniques

Signal Processing Advances in Wireless and Mobile Communications: Trends in channel estimation and equalization

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Publisher : Prentice Hall
ISBN 13 : 9780130271624
Total Pages : 433 pages
Book Rating : 4.2/5 (716 download)

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Book Synopsis Signal Processing Advances in Wireless and Mobile Communications: Trends in channel estimation and equalization by : Yingbo Hua

Download or read book Signal Processing Advances in Wireless and Mobile Communications: Trends in channel estimation and equalization written by Yingbo Hua and published by Prentice Hall. This book was released on 2001 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is volume 1 of a 2 volume set. This volume focuses on "channel estimation and equalization."

Multimedia Signal Processing

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Publisher : John Wiley & Sons
ISBN 13 : 9780470066492
Total Pages : 680 pages
Book Rating : 4.0/5 (664 download)

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Book Synopsis Multimedia Signal Processing by : Saeed V. Vaseghi

Download or read book Multimedia Signal Processing written by Saeed V. Vaseghi and published by John Wiley & Sons. This book was released on 2007-10-22 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multimedia Signal Processing is a comprehensive and accessible text to the theory and applications of digital signal processing (DSP). The applications of DSP are pervasive and include multimedia systems, cellular communication, adaptive network management, radar, pattern recognition, medical signal processing, financial data forecasting, artificial intelligence, decision making, control systems and search engines. This book is organised in to three major parts making it a coherent and structured presentation of the theory and applications of digital signal processing. A range of important topics are covered in basic signal processing, model-based statistical signal processing and their applications. Part 1: Basic Digital Signal Processing gives an introduction to the topic, discussing sampling and quantization, Fourier analysis and synthesis, Z-transform, and digital filters. Part 2: Model-based Signal Processing covers probability and information models, Bayesian inference, Wiener filter, adaptive filters, linear prediction hidden Markov models and independent component analysis. Part 3: Applications of Signal Processing in Speech, Music and Telecommunications explains the topics of speech and music processing, echo cancellation, deconvolution and channel equalization, and mobile communication signal processing. Covers music signal processing, explains the anatomy and psychoacoustics of hearing and the design of MP3 music coder Examines speech processing technology including speech models, speech coding for mobile phones and speech recognition Covers single-input and multiple-inputs denoising methods, bandwidth extension and the recovery of lost speech packets in applications such as voice over IP (VoIP) Illustrated throughout, including numerous solved problems, Matlab experiments and demonstrations Companion website features Matlab and C++ programs with electronic copies of all figures. This book is ideal for researchers, postgraduates and senior undergraduates in the fields of digital signal processing, telecommunications and statistical data analysis. It will also be a valuable text to professional engineers in telecommunications and audio and signal processing industries.

Signal Processing Aspects of Cell-Free Massive MIMO

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Author :
Publisher : Linköping University Electronic Press
ISBN 13 : 9176852245
Total Pages : 35 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Signal Processing Aspects of Cell-Free Massive MIMO by : Giovanni Interdonato

Download or read book Signal Processing Aspects of Cell-Free Massive MIMO written by Giovanni Interdonato and published by Linköping University Electronic Press. This book was released on 2019-03-20 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fifth generation of mobile communication systems (5G) promises unprecedented levels of connectivity and quality of service (QoS) to satisfy the incessant growth in the number of mobile smart devices and the huge increase in data demand. One of the primary ways 5G network technology will be accomplished is through network densification, namely increasing the number of antennas per site and deploying smaller and smaller cells. Massive MIMO, where MIMO stands for multiple-input multiple-output, is widely expected to be a key enabler of 5G. This technology leverages an aggressive spatial multiplexing, from using a large number of transmitting/receiving antennas, to multiply the capacity of a wireless channel. A massive MIMO base station (BS) is equipped with a large number of antennas, much larger than the number of active users. The users are coherently served by all the antennas, in the same time-frequency resources but separated in the spatial domain by receiving very directive signals. By supporting such a highly spatially-focused transmission (precoding), massive MIMO provides higher spectral and energy efficiency, and reduces the inter-cell interference compared to existing mobile systems. The inter-cell interference is however becoming the major bottleneck as we densify the networks. It cannot be removed as long as we rely on a network-centric implementation, since the inter-cell interference concept is inherent to the cellular paradigm. Cell-free massive MIMO refers to a massive MIMO system where the BS antennas, herein referred to as access points (APs), are geographically spread out. The APs are connected, through a fronthaul network, to a central processing unit (CPU) which is responsible for coordinating the coherent joint transmission. Such a distributed architecture provides additional macro-diversity, and the co-processing at multiple APs entirely suppresses the inter-cell interference. Each user is surrounded by serving APs and experiences no cell boundaries. This user-centric approach, combined with the system scalability that characterizes the massive MIMO design, constitutes a paradigm shift compared to the conventional centralized and distributed wireless communication systems. On the other hand, such a distributed system requires higher capacity of back/front-haul connections, and the signal co-processing increases the signaling overhead. In this thesis, we focus on some signal processing aspects of cell-free massive MIMO. More specifically, we firstly investigate if the downlink channel estimation, via downlink pilots, brings gains to cell-free massive MIMO or the statistical channel state information (CSI) knowledge at the users is enough to reliably perform data decoding, as in conventional co-located massive MIMO. Allocating downlink pilots is costly resource-wise, thus we also propose resource saving-oriented strategies for downlink pilot assignment. Secondly, we study further fully distributed and scalable precoding schemes in order to outperform cell-free massive MIMO in its canonical form, which consists in single-antenna APs implementing conjugate beamforming (also known as maximum ratio transmission).

Recent Advances in Information, Communications and Signal Processing

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Publisher : CRC Press
ISBN 13 : 1000795926
Total Pages : 218 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Recent Advances in Information, Communications and Signal Processing by : Andy W. H. Khong

Download or read book Recent Advances in Information, Communications and Signal Processing written by Andy W. H. Khong and published by CRC Press. This book was released on 2022-09-01 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in information, communications and signal processing has brought about new services, applications and functions in a large number of fields which include consumer electronics, biomedical devices and defence. These applications play an important role in advancing technologies to enhance human life in general. Recent Advances in Information, Communications and Signal Processing aims to give students, researchers, and engineers information pertaining to recent advances in these fields. In terms of research in signal processing topics, the two chapters included in this book have a strong emphasis on advances in algorithmic development in the biomedical, and human-computer interfaces domain areas. More specifically, the use of deep learning for placental maturity staging is discussed as well as the use of vibration analysis for localising impacts on surfaces for human-computer applications. In terms of communications signal processing, advances in new wireless communication such as NOMA (non-orthogonal multiple access) and millimetre-wave antenna design for 5G cellular mobile radio, as well as innovations in LDPC (low density parity check code) decoding and networking coding, are featured.

Signal Processing for Neuroscientists

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Publisher : Elsevier
ISBN 13 : 9780080467757
Total Pages : 320 pages
Book Rating : 4.4/5 (677 download)

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Book Synopsis Signal Processing for Neuroscientists by : Wim van Drongelen

Download or read book Signal Processing for Neuroscientists written by Wim van Drongelen and published by Elsevier. This book was released on 2006-12-18 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signal Processing for Neuroscientists introduces analysis techniques primarily aimed at neuroscientists and biomedical engineering students with a reasonable but modest background in mathematics, physics, and computer programming. The focus of this text is on what can be considered the ‘golden trio’ in the signal processing field: averaging, Fourier analysis, and filtering. Techniques such as convolution, correlation, coherence, and wavelet analysis are considered in the context of time and frequency domain analysis. The whole spectrum of signal analysis is covered, ranging from data acquisition to data processing; and from the mathematical background of the analysis to the practical application of processing algorithms. Overall, the approach to the mathematics is informal with a focus on basic understanding of the methods and their interrelationships rather than detailed proofs or derivations. One of the principle goals is to provide the reader with the background required to understand the principles of commercially available analyses software, and to allow him/her to construct his/her own analysis tools in an environment such as MATLAB®. Multiple color illustrations are integrated in the text Includes an introduction to biomedical signals, noise characteristics, and recording techniques Basics and background for more advanced topics can be found in extensive notes and appendices A Companion Website hosts the MATLAB scripts and several data files: http://www.elsevierdirect.com/companion.jsp?ISBN=9780123708670

Foundations of User-Centric Cell-Free Massive MIMO

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Publisher :
ISBN 13 : 9781680837902
Total Pages : 328 pages
Book Rating : 4.8/5 (379 download)

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Book Synopsis Foundations of User-Centric Cell-Free Massive MIMO by : Özlem Tugfe Demir

Download or read book Foundations of User-Centric Cell-Free Massive MIMO written by Özlem Tugfe Demir and published by . This book was released on 2021-01-25 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern day cellular mobile networks use Massive MIMO technology to extend range and service multiple devices within a cell. This has brought tremendous improvements in the high peak data rates that can be handled. Nevertheless, one of the characteristics of this technology is large variations in the quality of service dependent on where the end user is located in any given cell. This becomes increasingly problematic when we are creating a society where wireless access is supposed to be ubiquitous. When payments, navigation, entertainment, and control of autonomous vehicles are all relying on wireless connectivity the primary goal for future mobile networks should not be to increase the peak rates, but the rates that can be guaranteed to the vast majority of the locations in the geographical coverage area. The cellular network architecture was not designed for high-rate data services but for low-rate voice services, thus it is time to look beyond the cellular paradigm and make a clean-slate network design that can reach the performance requirements of the future. This monograph considers the cell-free network architecture that is designed to reach the aforementioned goal of uniformly high data rates everywhere. The authors introduce the concept of a cell-free network before laying out the foundations of what is required to design and build such a network. They cover the foundations of channel estimation, signal processing, pilot assignment, dynamic cooperation cluster formation, power optimization, fronthaul signaling, and spectral efficiency evaluation in uplink and downlink under different degrees of cooperation among the access points and arbitrary linear combining and precoding. This monograph provides the reader with all the fundamental information required to design and build the next generation mobile networks without being hindered by the inherent restrictions of modern cellular-based technology.

MIMO Communication for Cellular Networks

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387775234
Total Pages : 329 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis MIMO Communication for Cellular Networks by : Howard Huang

Download or read book MIMO Communication for Cellular Networks written by Howard Huang and published by Springer Science & Business Media. This book was released on 2011-11-19 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the theoretical foundations of multiple-antenna techniques evolve and as these multiple-input multiple-output (MIMO) techniques become essential for providing high data rates in wireless systems, there is a growing need to understand the performance limits of MIMO in practical networks. To address this need, MIMO Communication for Cellular Networks presents a systematic description of MIMO technology classes and a framework for MIMO system design that takes into account the essential physical-layer features of practical cellular networks. In contrast to works that focus on the theoretical performance of abstract MIMO channels, MIMO Communication for Cellular Networks emphasizes the practical performance of realistic MIMO systems. A unified set of system simulation results highlights relative performance gains of different MIMO techniques and provides insights into how best to use multiple antennas in cellular networks under various conditions. MIMO Communication for Cellular Networks describes single-user, multiuser, network MIMO technologies and system-level aspects of cellular networks, including channel modeling, resource scheduling, interference mitigation, and simulation methodologies. The key concepts are presented with sufficient generality to be applied to a wide range of wireless systems, including those based on cellular standards such as LTE, LTE-Advanced, WiMAX, and WiMAX2. The book is intended for use by graduate students, researchers, and practicing engineers interested in the physical-layer design of state-of-the-art wireless systems.

Introduction to Wireless Digital Communication

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Publisher : Prentice Hall
ISBN 13 : 0134431847
Total Pages : 685 pages
Book Rating : 4.1/5 (344 download)

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Book Synopsis Introduction to Wireless Digital Communication by : Robert W. Heath Jr.

Download or read book Introduction to Wireless Digital Communication written by Robert W. Heath Jr. and published by Prentice Hall. This book was released on 2017-04-04 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Accessible Guide to Modern Wireless Communication for Undergraduates, Graduates, and Practicing Electrical Engineers Wireless communication is a critical discipline of electrical engineering and computer science, yet the concepts have remained elusive for students who are not specialists in the area. This text makes digital communication and receiver algorithms for wireless communication broadly accessible to undergraduates, graduates, and practicing electrical engineers. Notably, the book builds on a signal processing foundation and does not require prior courses on analog or digital communication. Introduction to Wireless Digital Communication establishes the principles of communication, from a digital signal processing perspective, including key mathematical background, transmitter and receiver signal processing algorithms, channel models, and generalizations to multiple antennas. Robert Heath’s “less is more” approach focuses on typical solutions to common problems in wireless engineering. Heath presents digital communication fundamentals from a signal processing perspective, focusing on the complex pulse amplitude modulation approach used in most commercial wireless systems. He describes specific receiver algorithms for implementing wireless communication links, including synchronization, carrier frequency offset estimation, channel estimation, and equalization. While most concepts are presented for systems with single transmit and receive antennas, Heath concludes by extending those concepts to contemporary MIMO systems. To promote learning, each chapter includes previews, bullet-point summaries, examples, and numerous homework problems to help readers test their knowledge. Basics of wireless communication: applications, history, and the central role of signal processing Digital communication essentials: components, channels, distortion, coding/decoding, encryption, and modulation/demodulation Signal processing: linear time invariant systems, probability/random processes, Fourier transforms, derivation of complex baseband signal representation and equivalent channels, and multi-rate signal processing Least-squared estimation techniques that build on the linear algebra typically taught to electrical engineering undergraduates Complex pulse amplitude modulation: symbol mapping, constellations, signal bandwidth, and noise Synchronization, including symbol, frame, and carrier frequency offset Frequency selective channel estimation and equalization MIMO techniques using multiple transmit and/or receive antennas, including SIMO, MISO, and MIMO-OFDM Register your product at informit.com/register for convenient access to downloads, updates, and corrections as they become available.

Genomic Signal Processing

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Author :
Publisher : Princeton University Press
ISBN 13 : 1400865263
Total Pages : 314 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis Genomic Signal Processing by : Ilya Shmulevich

Download or read book Genomic Signal Processing written by Ilya Shmulevich and published by Princeton University Press. This book was released on 2014-09-08 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic signal processing (GSP) can be defined as the analysis, processing, and use of genomic signals to gain biological knowledge, and the translation of that knowledge into systems-based applications that can be used to diagnose and treat genetic diseases. Situated at the crossroads of engineering, biology, mathematics, statistics, and computer science, GSP requires the development of both nonlinear dynamical models that adequately represent genomic regulation, and diagnostic and therapeutic tools based on these models. This book facilitates these developments by providing rigorous mathematical definitions and propositions for the main elements of GSP and by paying attention to the validity of models relative to the data. Ilya Shmulevich and Edward Dougherty cover real-world situations and explain their mathematical modeling in relation to systems biology and systems medicine. Genomic Signal Processing makes a major contribution to computational biology, systems biology, and translational genomics by providing a self-contained explanation of the fundamental mathematical issues facing researchers in four areas: classification, clustering, network modeling, and network intervention.