Biophysical Analysis of GAP-junction Channels Involved in Congenital Diseases

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (955 download)

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Book Synopsis Biophysical Analysis of GAP-junction Channels Involved in Congenital Diseases by : Victor Hugo Hernandez Gonzalez

Download or read book Biophysical Analysis of GAP-junction Channels Involved in Congenital Diseases written by Victor Hugo Hernandez Gonzalez and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cell-Cell Channels

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Publisher : Springer Science & Business Media
ISBN 13 : 0387360581
Total Pages : 331 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Cell-Cell Channels by : František Baluška

Download or read book Cell-Cell Channels written by František Baluška and published by Springer Science & Business Media. This book was released on 2006-08-28 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers cell-cell channels at all levels of biological organization. The purpose of this book is to document that cells are not physically separated and fully autonomous units of biological life as stated by the currently valid Cell Theory. If not the cell then some lower level unit must fulfill this role. The book deals also with the identity of this elusive unit of biological life.

The Ichthyoses

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Publisher : Springer Science & Business Media
ISBN 13 : 3642736505
Total Pages : 270 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Ichthyoses by : Heiko Traupe

Download or read book The Ichthyoses written by Heiko Traupe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a great pleasure for me to see this work in print. As outlined by Dr. Traupe, at least 20 different types of ichthyosis have been identified to date. This book will effectively help to establish a correct diagnosis, as a basis for genetic counseling. Dr. Traupe proposes a new classification of the ichthyoses, based on reason able clinical criteria. He lets the reader share in his enormous knowledge and safely guides him through the difficult field of nomenclature. He describes the particular nature of these scaling disorders in a manner as simple as possible. During the last few years, research on ichthyosis has become a fascinating scientific challenge due to the introduction of novel investigative approaches. The main advantage of this book lies in the fact that the author successfully combines recent achievements made in lipid analysis, enzymology, electron microscopy, and molecular genetics. Heiko Traupe began his career in dermatology 11 years ago, as a resident in the Department of Dermatology in Munster. As we were both interested in the genetic aspects of skin diseases, this was the starting point of a most fruitful collaboration, which is still continuing. During our common work in Munster, Dr. Traupe was able, thanks to his unceasing clinical curiosity, to describe many novel aspects within the field of ichthyosis, and I took pride in coauthoring papers on new items such as cryptorchidism as a fea ture associated with X-linked recessive ichthyosis, autosomal dominant lamellar ichthyosis, and alopecia ichthyotica.

The Cardiomyopathic Heart

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Publisher : Raven Press (ID)
ISBN 13 :
Total Pages : 506 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Cardiomyopathic Heart by : Makoto Nagano

Download or read book The Cardiomyopathic Heart written by Makoto Nagano and published by Raven Press (ID). This book was released on 1994 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gap Junctions in the Nervous System

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Publisher : Springer Science & Business Media
ISBN 13 : 3662219352
Total Pages : 321 pages
Book Rating : 4.6/5 (622 download)

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Book Synopsis Gap Junctions in the Nervous System by : David C. Spray

Download or read book Gap Junctions in the Nervous System written by David C. Spray and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the types of gap junction proteins (connexins) and their distribution within the nervous system, the physiological properties of channels formed of each connexin, and the role of gap junction channels in functions of normal and pathological brain and peripheral nerve. Although glial tissue is emphasized, additional groups of chapters deal with neurons in the central nervous system and with the retina.

Pattern Formation in Zebrafish

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Publisher : Springer
ISBN 13 : 9783642536670
Total Pages : 438 pages
Book Rating : 4.5/5 (366 download)

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Book Synopsis Pattern Formation in Zebrafish by : Lilianna Solnica-Krezel

Download or read book Pattern Formation in Zebrafish written by Lilianna Solnica-Krezel and published by Springer. This book was released on 2012-11-28 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by leading experts in the field, this book provides the first comprehensive overview of the mechanisms of early patterning and morphogenesis in zebrafish. It summarizes the current knowledge and the key questions for the next decade of research.

Ion Channels in Health and Sickness

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Publisher : BoD – Books on Demand
ISBN 13 : 1789842271
Total Pages : 204 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Ion Channels in Health and Sickness by : Fatima Shad Kaneez

Download or read book Ion Channels in Health and Sickness written by Fatima Shad Kaneez and published by BoD – Books on Demand. This book was released on 2018-10-10 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion channels are proteins that make pores in the membranes of excitable cells present both in the brain and the body. These cells are not only responsible for converting chemical and mechanical stimuli into the electrical signals but are also liable for monitoring vital functions. All our activities, from the blinking of our eyes to the beating of our heart and all our senses from smell to sight, touch, taste and hearing are regulated by the ion channels. This book will take us on an expedition describing the role of ion channels in congenital and acquired diseases and the challenges and limitations scientist are facing in the development of drugs targeting these membrane proteins.

Ion Channel Diseases

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Publisher : Academic Press
ISBN 13 : 0080923100
Total Pages : 168 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Ion Channel Diseases by :

Download or read book Ion Channel Diseases written by and published by Academic Press. This book was released on 2011-09-06 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ion channel dysfunction in humans leads to impairment of the excitable processes necessary for the normal function of several tissues, such as muscle and brain. It follows that an increasing number of human diseases have been associated with malfunctioning ion channels, many of which have a genetic component. This volume of Advances in Genetics presents a broad and comprehensive overview of the inherited channelopathies in humans, including clinical, genetic and molecular aspects of these conditions. Keeping true to the scope of the serial, novel genomic and modeling research approaches and a review of potential therapeutic approaches for each of these conditions are also incorporated.

Molecular Biology of The Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gap Junction Channels and Hemichannels

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Publisher : CRC Press
ISBN 13 : 9780367658441
Total Pages : 289 pages
Book Rating : 4.6/5 (584 download)

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Book Synopsis Gap Junction Channels and Hemichannels by : Taylor & Francis Group

Download or read book Gap Junction Channels and Hemichannels written by Taylor & Francis Group and published by CRC Press. This book was released on 2021-03-30 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gap junction channels are a group of intercellular channels expressed in tissues and organs to synchronize many physiological processes. A gap junction channel is formed by the docking of two hemichannels, and each hemichannel is a hexamer of connexins. The field of gap junction channel and hemichannel research has recently exploded and became one of the most active areas of cell biology. Numerous novel approaches and techniques have been developed, but there is no single book dedicated to the unique techniques and protocols employed for the research on these large pore channels. This book fills the gap and focuses on protocols, approaches and reviews of gap junction channels and connexin hemichannels. It will be a useful reference for graduate students, postdoctoral fellows and researchers. Anyone with an interest in gap junction channels and hemichannels will need this summary of state-of-the-art techniques and protocols.

Intercellular Communication through Gap Junctions

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Publisher : Newnes
ISBN 13 : 0444599525
Total Pages : 474 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Intercellular Communication through Gap Junctions by : Y. Kanno

Download or read book Intercellular Communication through Gap Junctions written by Y. Kanno and published by Newnes. This book was released on 1995-02-09 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on intercellular communication through gap junctions has continued to expand, and the meeting on which this book is based brought together many scientists from many different countries and disciplines. In line with the objective of the meeting, this volume focuses on the biological meaning of intercellular communication through gap junctions in various organs. The most recent up-to-date findings have been included in this extensive volume, valuable to all those interested in this rapidly expanding field.

Intercellular Communication in Cancer

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Publisher : Springer
ISBN 13 : 9401773807
Total Pages : 370 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Intercellular Communication in Cancer by : Mustapha Kandouz

Download or read book Intercellular Communication in Cancer written by Mustapha Kandouz and published by Springer. This book was released on 2015-11-20 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells are by nature compelled to live in groups. They develop dependence over signaling cues received from their microenvironment, in particular from other cells, whether of their own “kind” or of a different type. Therefore, communicating with these cells is a critical aspect of their behavior and fate, as they live and die normally or as they undergo disease-related pathological changes, with dramatic repercussions. In this book, we have asked expert researchers in the field of Intercellular Communication in Cancer to provide chapters on different aspects of interaction between neighboring cells, in the context of cancer diseases. We have specifically focused our efforts on membrane-to-membrane contact-based rather than growth factors-mediated modes of intercellular communications. The contributing authors provide an extensive overview of their respective area of specialization, with an in-depth discussion of the molecular mechanisms of cell-cell interactions, the impact on tumor progression and response to therapies, as well as the cancer diagnostic value of this scientific information. This book aims to introduce essential aspects of the normal and pathological cellular fate and homeostasis to both scientists and clinicians, and also to provide established researchers with an update on the novelties and future directions this expanding field is witnessing.

Hereditary Hearing Loss and Its Syndromes

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Publisher : Oxford University Press
ISBN 13 : 0199313881
Total Pages : 749 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Hereditary Hearing Loss and Its Syndromes by : Helga V. Toriello

Download or read book Hereditary Hearing Loss and Its Syndromes written by Helga V. Toriello and published by Oxford University Press. This book was released on 2013-06-20 with total page 749 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third edition of the foremost medical reference on hereditary hearing loss. Chapters on epidemiology, embryology, non-syndromic hearing loss, and syndromic forms of hearing loss have all been updated with particular attention to the vast amount of new information on molecular mechanisms, and chapters on clinical and molecular diagnosis and on genetic susceptibility to ototoxic factors have been added. As in previous editions, the syndromes are grouped by system (visual, metabolic, cardiologic, neurologic, musculoskeletal, endocrine, etc.), with each chapter written by a recognized expert in the field. Written for practicing clinicians, this volume is an excellent reference for physicians, audiologists, and other professionals working with individuals with hearing loss and their families, and can also serve as a text for clinical training programs and for researchers in the hearing sciences.

Molecular and Cellular Biophysics

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Publisher : Cambridge University Press
ISBN 13 : 9780521624411
Total Pages : 536 pages
Book Rating : 4.6/5 (244 download)

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Book Synopsis Molecular and Cellular Biophysics by : Meyer B. Jackson

Download or read book Molecular and Cellular Biophysics written by Meyer B. Jackson and published by Cambridge University Press. This book was released on 2006-01-12 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. Students who have taken physical chemistry and calculus courses will find this book an accessible and valuable aid in learning how these concepts can be used in biological research. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples. Conformational transitions of proteins are studied first using thermodynamics, and subsequently with kinetics. Allosteric theory is developed as the synthesis of conformational transitions and association reactions. Basic ideas of thermodynamics and kinetics are applied to topics such as protein folding, enzyme catalysis and ion channel permeation. These concepts are then used as the building blocks in a treatment of membrane excitability. Through these examples, students will gain an understanding of the general importance and broad applicability of biophysical principles to biological problems.

Astrocytes and Epilepsy

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Publisher : Academic Press
ISBN 13 : 0128026243
Total Pages : 395 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Astrocytes and Epilepsy by : Jacqueline A. Hubbard

Download or read book Astrocytes and Epilepsy written by Jacqueline A. Hubbard and published by Academic Press. This book was released on 2016-07-05 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy. Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume Provides a great resource on the field of astrocyte biology and astrocyte-neuron interactions Details potential therapeutic targets, including chapters on gap junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation

Rhythms of the Brain

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Publisher : Oxford University Press
ISBN 13 : 0199828237
Total Pages : 465 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Rhythms of the Brain by : G. Buzsáki

Download or read book Rhythms of the Brain written by G. Buzsáki and published by Oxford University Press. This book was released on 2011 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies of mechanisms in the brain that allow complicated things to happen in a coordinated fashion have produced some of the most spectacular discoveries in neuroscience. This book provides eloquent support for the idea that spontaneous neuron activity, far from being mere noise, is actually the source of our cognitive abilities. It takes a fresh look at the coevolution of structure and function in the mammalian brain, illustrating how self-emerged oscillatory timing is the brain's fundamental organizer of neuronal information. The small-world-like connectivity of the cerebral cortex allows for global computation on multiple spatial and temporal scales. The perpetual interactions among the multiple network oscillators keep cortical systems in a highly sensitive "metastable" state and provide energy-efficient synchronizing mechanisms via weak links. In a sequence of "cycles," György Buzsáki guides the reader from the physics of oscillations through neuronal assembly organization to complex cognitive processing and memory storage. His clear, fluid writing-accessible to any reader with some scientific knowledge-is supplemented by extensive footnotes and references that make it just as gratifying and instructive a read for the specialist. The coherent view of a single author who has been at the forefront of research in this exciting field, this volume is essential reading for anyone interested in our rapidly evolving understanding of the brain.

Webvision

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (53 download)

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Book Synopsis Webvision by : Helga Kolb

Download or read book Webvision written by Helga Kolb and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: