Molecular And Cellular Biophysics

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Integrated Molecular and Cellular Biophysics

Author : Valerica Raicu
Publisher : Springer Science & Business Media
ISBN 13 : 1402082681
Total Pages : 254 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Integrated Molecular and Cellular Biophysics by : Valerica Raicu

Download or read book Integrated Molecular and Cellular Biophysics written by Valerica Raicu and published by Springer Science & Business Media. This book was released on 2008-06-17 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysics represents perhaps one of the best examples of interdisciplinary research areas, where concepts and methods from disciplines such as physics, biology, b- chemistry, colloid chemistry, and physiology are integrated. It is by no means a new ?eld of study and has actually been around, initially as quantitative physiology and partly as colloid science, for over a hundred years. For a long time, biophysics has been taught and practiced as a research discipline mostly in medical schools and life sciences departments, and excellent biophysics textbooks have been published that are targeted at a biologically literate audience. With a few exceptions, it is only relatively recently that biophysics has started to be recognized as a physical science and integrated into physics departments’ curr- ula, sometimes under the new name of biological physics. In this period of cryst- lization and possible rede?nition of biophysics, there still exists some uncertainty as to what biophysics might actually represent. A particular tendency among phy- cists is to associate biophysics research with the development of powerful new te- niques that should eventually be used not by physicists to study physical processes in living matter, but by biologists in their biological investigations. There is value in that judgment, and excellent books have been published that introduce the int- ested reader to the use of physical principles for the development of new methods of investigation in life sciences.

Molecular and Cellular Biophysics

Author : Meyer B. Jackson
Publisher : Cambridge University Press
ISBN 13 : 9780521624411
Total Pages : 536 pages
Book Rating : 4.6/5 (244 download)

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Book Synopsis Molecular and Cellular Biophysics by : Meyer B. Jackson

Download or read book Molecular and Cellular Biophysics written by Meyer B. Jackson and published by Cambridge University Press. This book was released on 2006-01-12 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. Students who have taken physical chemistry and calculus courses will find this book an accessible and valuable aid in learning how these concepts can be used in biological research. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples. Conformational transitions of proteins are studied first using thermodynamics, and subsequently with kinetics. Allosteric theory is developed as the synthesis of conformational transitions and association reactions. Basic ideas of thermodynamics and kinetics are applied to topics such as protein folding, enzyme catalysis and ion channel permeation. These concepts are then used as the building blocks in a treatment of membrane excitability. Through these examples, students will gain an understanding of the general importance and broad applicability of biophysical principles to biological problems.

Molecular and Cellular Biophysics

Author : Meyer B. Jackson
Publisher : Cambridge University Press
ISBN 13 : 9781139447249
Total Pages : pages
Book Rating : 4.4/5 (472 download)

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Book Synopsis Molecular and Cellular Biophysics by : Meyer B. Jackson

Download or read book Molecular and Cellular Biophysics written by Meyer B. Jackson and published by Cambridge University Press. This book was released on 2006-01-12 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. Students who have taken physical chemistry and calculus courses will find this book an accessible and valuable aid in learning how these concepts can be used in biological research. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples. Conformational transitions of proteins are studied first using thermodynamics, and subsequently with kinetics. Allosteric theory is developed as the synthesis of conformational transitions and association reactions. Basic ideas of thermodynamics and kinetics are applied to topics such as protein folding, enzyme catalysis and ion channel permeation. These concepts are then used as the building blocks in a treatment of membrane excitability. Through these examples, students will gain an understanding of the general importance and broad applicability of biophysical principles to biological problems.

Single-Molecule Cellular Biophysics

Author : Mark C. Leake
Publisher : Cambridge University Press
ISBN 13 : 1139619349
Total Pages : pages
Book Rating : 4.1/5 (396 download)

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Book Synopsis Single-Molecule Cellular Biophysics by : Mark C. Leake

Download or read book Single-Molecule Cellular Biophysics written by Mark C. Leake and published by Cambridge University Press. This book was released on 2013-01-31 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in single molecule science have presented a new branch of science: single molecule cellular biophysics, combining classical cell biology with cutting-edge single molecule biophysics. This textbook explains the essential elements of this new discipline, from the state-of-the-art single molecule techniques to real-world applications in unravelling the inner workings of the cell. Every effort has been made to ensure the text can be easily understood by students from both the physical and life sciences. Mathematical derivations are kept to a minimum whilst unnecessary biological terminology is avoided and text boxes provide readers from either background with additional information. 100 end-of-chapter exercises are divided into those aimed at physical sciences students, those aimed at life science students and those that can be tackled by students from both disciplines. The use of case studies and real research examples make this textbook indispensable for undergraduate students entering this exciting field.

Cellular Biophysics and Modeling

Author : Greg Conradi Smith
Publisher : Cambridge University Press
ISBN 13 : 1107005361
Total Pages : 395 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Cellular Biophysics and Modeling by : Greg Conradi Smith

Download or read book Cellular Biophysics and Modeling written by Greg Conradi Smith and published by Cambridge University Press. This book was released on 2019-03-14 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: What every neuroscientist should know about the mathematical modeling of excitable cells, presented at an introductory level.

Methods in Molecular Biophysics

Author : Nathan R. Zaccai
Publisher : Cambridge University Press
ISBN 13 : 1108508804
Total Pages : 710 pages
Book Rating : 4.1/5 (85 download)

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Book Synopsis Methods in Molecular Biophysics by : Nathan R. Zaccai

Download or read book Methods in Molecular Biophysics written by Nathan R. Zaccai and published by Cambridge University Press. This book was released on 2017-05-18 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy, electron microscopy, molecular dynamics simulations and nuclear magnetic resonance. Each method is explained in detail using examples of real-world applications. Short asides are provided throughout to ensure that explanations are accessible to life scientists, physicists and those with medical backgrounds. The book remains an unparalleled and comprehensive resource for graduate students of biophysics and medical physics in science and medical schools, as well as for research scientists looking for an introduction to techniques from across this interdisciplinary field.

Computer Simulation and Data Analysis in Molecular Biology and Biophysics

Author : Victor Bloomfield
Publisher : Springer Science & Business Media
ISBN 13 : 1441900837
Total Pages : 325 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Computer Simulation and Data Analysis in Molecular Biology and Biophysics by : Victor Bloomfield

Download or read book Computer Simulation and Data Analysis in Molecular Biology and Biophysics written by Victor Bloomfield and published by Springer Science & Business Media. This book was released on 2009-06-05 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to two important aspects of modern bioch- istry, molecular biology, and biophysics: computer simulation and data analysis. My aim is to introduce the tools that will enable students to learn and use some f- damental methods to construct quantitative models of biological mechanisms, both deterministicandwithsomeelementsofrandomness;tolearnhowconceptsofpr- ability can help to understand important features of DNA sequences; and to apply a useful set of statistical methods to analysis of experimental data. The availability of very capable but inexpensive personal computers and software makes it possible to do such work at a much higher level, but in a much easier way, than ever before. TheExecutiveSummaryofthein?uential2003reportfromtheNationalAcademy of Sciences, “BIO 2010: Transforming Undergraduate Education for Future - search Biologists” [12], begins The interplay of the recombinant DNA, instrumentation, and digital revolutions has p- foundly transformed biological research. The con?uence of these three innovations has led to important discoveries, such as the mapping of the human genome. How biologists design, perform, and analyze experiments is changing swiftly. Biological concepts and models are becoming more quantitative, and biological research has become critically dependent on concepts and methods drawn from other scienti?c disciplines. The connections between the biological sciences and the physical sciences, mathematics, and computer science are rapidly becoming deeper and more extensive.

Quantitative Fundamentals of Molecular and Cellular Bioengineering

Author : K. Dane Wittrup
Publisher : MIT Press
ISBN 13 : 0262042657
Total Pages : 593 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Quantitative Fundamentals of Molecular and Cellular Bioengineering by : K. Dane Wittrup

Download or read book Quantitative Fundamentals of Molecular and Cellular Bioengineering written by K. Dane Wittrup and published by MIT Press. This book was released on 2020-01-07 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive presentation of essential topics for biological engineers, focusing on the development and application of dynamic models of biomolecular and cellular phenomena. This book describes the fundamental molecular and cellular events responsible for biological function, develops models to study biomolecular and cellular phenomena, and shows, with examples, how models are applied in the design and interpretation of experiments on biological systems. Integrating molecular cell biology with quantitative engineering analysis and design, it is the first textbook to offer a comprehensive presentation of these essential topics for chemical and biological engineering. The book systematically develops the concepts necessary to understand and study complex biological phenomena, moving from the simplest elements at the smallest scale and progressively adding complexity at the cellular organizational level, focusing on experimental testing of mechanistic hypotheses. After introducing the motivations for formulation of mathematical rate process models in biology, the text goes on to cover such topics as noncovalent binding interactions; quantitative descriptions of the transient, steady state, and equilibrium interactions of proteins and their ligands; enzyme kinetics; gene expression and protein trafficking; network dynamics; quantitative descriptions of growth dynamics; coupled transport and reaction; and discrete stochastic processes. The textbook is intended for advanced undergraduate and graduate courses in chemical engineering and bioengineering, and has been developed by the authors for classes they teach at MIT and the University of Minnesota.

Introduction to Cellular Biophysics, Volume 1

Author : Armin Kargol
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1643274104
Total Pages : 117 pages
Book Rating : 4.6/5 (432 download)

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Book Synopsis Introduction to Cellular Biophysics, Volume 1 by : Armin Kargol

Download or read book Introduction to Cellular Biophysics, Volume 1 written by Armin Kargol and published by Morgan & Claypool Publishers. This book was released on 2019-03-29 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or entire organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What does the cell consist of? Where are its organelles? What function does each organelle fulfil? From a chemists' point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, one of the main questions is the physical movement of all these molecules between organelles within the cell, as well as their exchange with the extracellular medium. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and that in turn leads to the biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfil its function as a part of a larger organ or organism. This book is an inventory of physical transport processes occurring in cells while the second volume will be a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.

Physics and Biology

Author : M Volkenstein
Publisher : Elsevier
ISBN 13 : 0323160735
Total Pages : 174 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Physics and Biology by : M Volkenstein

Download or read book Physics and Biology written by M Volkenstein and published by Elsevier. This book was released on 2012-12-02 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physics and Biology demonstrates the unlimited possibilities of physics in explaining a variety of biological phenomena. It explores developments in biophysics and the most general problems of biological thermodynamics, information theory, and the physical theory of biological development and how they are all connected with the biophysics of complicated systems. Organized into 13 chapters, this volume begins with a historical overview of biophysics, with emphasis on molecular biophysics, followed by a discussion of the biophysics of the cell and of complicated systems. It then introduces the reader to the physical basis of theoretical chemistry and biologically functional substances, with emphasis on some concepts that are necessary for the understanding of molecular biophysics. The next chapters focus on some properties of biopolymers such as proteins and nucleic acids, how molecules interact with each other, and the peculiarities of macromolecules. More specifically, the molecules of organic substances, the chemical reaction involved in molecular interactions, van der Waals forces, and the role of hydrogen bonds in biological processes are considered. The final chapter analyzes the physicochemical basis of the functions of biological molecules. This book will be a valuable resource for physicists, biologists, chemists, natural scientists, and anyone who wants help in tackling some important biophysics-related problems in the contemporary natural sciences.

Molecular and Cellular Biophysics

Author : Jack A. Tuszynski
Publisher : CRC Press
ISBN 13 : 1315357259
Total Pages : 320 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Molecular and Cellular Biophysics by : Jack A. Tuszynski

Download or read book Molecular and Cellular Biophysics written by Jack A. Tuszynski and published by CRC Press. This book was released on 2018-10-24 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: From quantum theory to statistical mechanics, the methodologies of physics are often used to explain some of life's most complex biological problems. Exploring this challenging yet fascinating area of study, Molecular and Cellular Biophysics covers both molecular and cellular structures as well as the biophysical processes that occur in these structures. Designed for advanced undergraduate and beginning graduate students in biophysics courses, this textbook features a quantitative approach that avoids being too abstract in its presentation. Logically organized from small-scale (molecular) to large-scale (cellular) systems, the text first defines life, discussing the scientific controversies between mechanists and vitalists, the characteristics of living things, and the evolution of life. It then delves into molecular structures, including nucleic acids, DNA, RNA, interatomic interactions, and hydrogen bonds. After looking at these smaller systems, the author probes the larger cellular structures. He examines the cytoplasm, the cytoskeleton, chromosomes, mitochondria, motor proteins, and more. The book concludes with discussions on biophysical processes, including oxidative phosphorylation, diffusion, bioenergetics, conformational transitions in proteins, vesicle transport, subcellular structure formation, and cell division.

Cellular Mechanics and Biophysics

Author : Claudia Tanja Mierke
Publisher : Springer Nature
ISBN 13 : 3030585328
Total Pages : 919 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Cellular Mechanics and Biophysics by : Claudia Tanja Mierke

Download or read book Cellular Mechanics and Biophysics written by Claudia Tanja Mierke and published by Springer Nature. This book was released on 2020-10-30 with total page 919 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the mechanical properties of cells, discussing the basic concepts and processes in the fields of immunology, biology, and biochemistry. It introduces and explains state-of-the-art biophysical methods and examines the role of mechanical properties in the cell/protein interaction with the connective tissue microenvironment. The book presents a unique perspective on cellular mechanics and biophysics by combining the mechanical, biological, physical, biochemical, medical, and immunological views, highlighting the importance of the mechanical properties of cells and biophysical measurement methods. The book guides readers through the complex and growing field of cellular mechanics and biophysics, connecting and discussing research findings from different fields such as biology, cell biology, immunology, physics, and medicine. Featuring suggestions for further reading throughout and addressing a wide selection of biophysical topics, this book is an indispensable guide for graduate and advanced undergraduate students in the fields of cellular mechanics and biophysics.

Physical Biology of the Cell

Author : Rob Phillips
Publisher : Garland Science
ISBN 13 : 1134111584
Total Pages : 1089 pages
Book Rating : 4.1/5 (341 download)

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Book Synopsis Physical Biology of the Cell by : Rob Phillips

Download or read book Physical Biology of the Cell written by Rob Phillips and published by Garland Science. This book was released on 2012-10-29 with total page 1089 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that

Cellular Biophysics, Volume 2

Author : Thomas Fischer Weiss
Publisher : National Geographic Books
ISBN 13 : 0262529572
Total Pages : 0 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Cellular Biophysics, Volume 2 by : Thomas Fischer Weiss

Download or read book Cellular Biophysics, Volume 2 written by Thomas Fischer Weiss and published by National Geographic Books. This book was released on 1996-03-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular Biophysics is a quantitatively oriented basic physiology text for senior undergraduate and graduate students in bioengineering, biophysics, physiology, and neuroscience programs. It will also serve as a major reference work for biophysicists. Developed from the author's notes for a course that he has taught at MIT for many years, these books provide a clear and logical explanation of the foundations of cell biophysics, teaching transport and the electrical properties of cells from a combined biological, physical, and engineering viewpoint. Each volume contains introductory chapters that motivate the material and present it in a broad historical context. Important experimental results and methods are described. Theories are derived almost always from first principles so that students develop an understanding of not only the predictions of the theory but also its limitations. Theoretical results are compared carefully with experimental findings and new results appear throughout. There are many time-tested exercises and problems as well as extensive lists of references. The volume on the electrical properties of cells covers both electrically inexcitable cells as well as electrically excitable cells such as neurons and muscle cells. Included are chapters on lumped-parameter and distributed-parameter models of cells, linear electric properties of cells, the Hodgkin-Huxley model of the giant axon of the squid, saltatory conduction in myelinated nerve fibers, and voltage-gated ion channels.

Molecular Biophysics for the Life Sciences

Author : Norma Allewell
Publisher : Springer Science & Business Media
ISBN 13 : 1461485487
Total Pages : 397 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Molecular Biophysics for the Life Sciences by : Norma Allewell

Download or read book Molecular Biophysics for the Life Sciences written by Norma Allewell and published by Springer Science & Business Media. This book was released on 2013-09-28 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an overview of the development and scope of molecular biophysics and in-depth discussions of the major experimental methods that enable biological macromolecules to be studied at atomic resolution. It also reviews the physical chemical concepts that are needed to interpret the experimental results and to understand how the structure, dynamics, and physical properties of biological macromolecules enable them to perform their biological functions. Reviews of research on three disparate biomolecular machines—DNA helicases, ATP synthases, and myosin--illustrate how the combination of theory and experiment leads to new insights and new questions.

Introduction to Cellular Biophysics, Volume 2

Author : Armin Kargol
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1643277561
Total Pages : 107 pages
Book Rating : 4.6/5 (432 download)

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Book Synopsis Introduction to Cellular Biophysics, Volume 2 by : Armin Kargol

Download or read book Introduction to Cellular Biophysics, Volume 2 written by Armin Kargol and published by Morgan & Claypool Publishers. This book was released on 2019-12-13 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What the cells consists of? Where are its organelles? What function each organelle fulfils? From a chemists’ point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, some of the fundamental questions are about the physical movement of all these molecules between organelles within the cell, their exchange with the extracellular medium, as well as electrical phenomena resulting from such transport. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and various electrical effects, and that in turn leads to biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfill its function as a part of a larger organ or organism. The first volume of this book is an inventory of physical transport processes occurring in cells while this second volume provides a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.

Molecular and Cellular Biology of Phagocytosis

Author : Maurice B. Hallett
Publisher : Springer Nature
ISBN 13 : 3030404064
Total Pages : 194 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Molecular and Cellular Biology of Phagocytosis by : Maurice B. Hallett

Download or read book Molecular and Cellular Biology of Phagocytosis written by Maurice B. Hallett and published by Springer Nature. This book was released on 2020-05-12 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phagocytosis is the engulfment of particulate matter by cells. It is a fundamental (and probably “primitive”) cell biological process which is important in single celled organisms such as amoeba; multicellular animals including coelenterates; and in higher animals. In humans and other mammals, specialised immune cells (phagocytes) utilise phagocytosis in their crucial role of engulfing and destroying infecting microbes. Yet, surprisingly, the biophysics and biochemistry underlying the process has only become clear recently with the advent of genetic manipulation and advances in single cell imaging. In this volume, the aim is to bring together recent fundamental advances that give a clear picture of the underlying mechanism involved in phagocytosis. Not only is this an important topic in its own right, but a full understanding of the process will have a potential impact on human medicine, since as antibiotics become less effective in fight infection, researchers are looking at alternative approaches, including enhancing the “natural” immunity brought about by immune phagocytes. The aim is to provide a comprehensive volume on the topic, with separate chapters on identified recent advances, each written by the major contributors in each area. In addition, the volume will attempt to give a wider overview than is often the case in single author reviews, with an emphasis here on the cell biological understanding of phagocytosis using biophysical approaches alongside the biochemical and imaging approaches.