Xenoestrogen And Impact On Mammalian Reproductive System

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Xenoestrogen and Impact on Mammalian Reproductive System

Author : Linee Goswami
Publisher : LAP Lambert Academic Publishing
ISBN 13 : 9783845430744
Total Pages : 84 pages
Book Rating : 4.4/5 (37 download)

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Book Synopsis Xenoestrogen and Impact on Mammalian Reproductive System by : Linee Goswami

Download or read book Xenoestrogen and Impact on Mammalian Reproductive System written by Linee Goswami and published by LAP Lambert Academic Publishing. This book was released on 2011-11 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies have revealed that there are numerous toxic chemicals available in the market since World War II which can act like natural hormone and fool the body's endocrine system. These endocrine disrupting chemicals or hormone mimics are called environmental estrogen or xenoestrogen. As many as 116 components have been identified as possible endocrine disrupting chemicals by European Commission in September 1999 out of which 50 endocrine disruptors including DDT, DDE, PCBs & even some pesticides like aldrin, dieldrin, heptachlor, kepone etc have been listed by WWF society. Environmental estrogens are ubiquitous in nature and are identified to be responsible for a number of physiological aberrations in human health as well as wildlife. A major area of concern has been in relation to the possible link between the effects of these chemicals and reported decline in sperm count along with the increasing reproductive disorders in living beings. This book particularly concentrates on industrial chemical Bisphenol-A, as a potential source of environmental estrogen.

Impact of Xenoestrogens on Reproductive Health

Author : Emma Curtis
Publisher :
ISBN 13 :
Total Pages : 30 pages
Book Rating : 4.:/5 (114 download)

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Book Synopsis Impact of Xenoestrogens on Reproductive Health by : Emma Curtis

Download or read book Impact of Xenoestrogens on Reproductive Health written by Emma Curtis and published by . This book was released on 2019 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: Xenoestrogens such as phthalates, parabens, bisphenol A, dichlorodiphenyltrichloroethane, and dioxins are compounds found in ordinary substances such as detergents, cosmetics, plastics, pesticides and herbicides (Sonnenschein & Soto, 1998). Estrogen is a vital component in the development of the male and female reproductive system. However, xenoestrogens mimic endogenous estrogenic signaling and exhibit endocrine disrupting properties that may cause long-lasting repercussions on human reproductive health. Xenoestrogen bind to both intracellular and membrane-bound estrogen receptors resulting in an inappropriate activation of tissue-specific estrogenic responses, leading to low sperm count in males and precocious puberty and polycystic ovarian syndrome in females (Shanle & Xu, 2011). Although the pathways of many xenoestrogens mechanism are unknown, the detrimental outcomes on reproductive health are evident.

Developmental Exposure to Xenoestrogens

Author : Durga Kolla
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (15 download)

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Book Synopsis Developmental Exposure to Xenoestrogens by : Durga Kolla

Download or read book Developmental Exposure to Xenoestrogens written by Durga Kolla and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans experience ubiquitous exposures to estrogenic environmental chemicals from food, personal care products, and other industrial and consumer goods. Bisphenol A (BPA), a well-studied xenoestrogen, is known to alter development of estrogen-sensitive organs including the brain, reproductive tract, and mammary gland. Bisphenol S (BPS), which has a similar chemical structure to BPA, is also used in many consumer products, but its effects on estrogen-sensitive organs in mammals has not been thoroughly examined. In our study, pregnant CD-1 mice were orally exposed to BPS or ethinyl estradiol (EE2, a positive control for estrogenicity) from gestational day 9 through postnatal day (PND) 2, the period when many estrogen-sensitive organs are developing. After weaning, the offspring were administered either oil (vehicle) or an estrogen challenge (1 [mu]g EE2/kg/day) for ten days starting at PND21 (prior to puberty), PND80 (early adulthood), or PND260 (later adulthood). Timing of puberty was evaluated in females by noting the date on which vaginal opening occurred. After the 10 day estrogen challenge, we evaluated the response of endocrine sensitive organs through measurements of organ weight, tissue morphology, and gene expression in both males and females. We observed dose- and sex-specific effects of BPS and EE2 treatment, as well as alterations in the responses of males and females to the estrogen challenge. This study sheds light on the effects of low dose xenoestrogen exposures on estrogen-sensitive organs including the reproductive tract and mammary gland. Furthermore, it improves our understanding of the influence of environmental chemicals on secular trends of earlier age of puberty in girls reported over the past few decades.

Endocrine Disruption and Human Health

Author : Philippa D. Darbre
Publisher : Academic Press
ISBN 13 : 0128011203
Total Pages : 390 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Endocrine Disruption and Human Health by : Philippa D. Darbre

Download or read book Endocrine Disruption and Human Health written by Philippa D. Darbre and published by Academic Press. This book was released on 2015-03-21 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations

Environmental Impacts on Reproductive Health and Fertility

Author : Tracey J. Woodruff
Publisher : Cambridge University Press
ISBN 13 : 9780521519526
Total Pages : 262 pages
Book Rating : 4.5/5 (195 download)

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Book Synopsis Environmental Impacts on Reproductive Health and Fertility by : Tracey J. Woodruff

Download or read book Environmental Impacts on Reproductive Health and Fertility written by Tracey J. Woodruff and published by Cambridge University Press. This book was released on 2010-01-28 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many reproductive and developmental health problems are caused by exposure to chemicals that are widely dispersed in our environment. These problems include infertility, miscarriage, poor pregnancy outcomes, abnormal fetal development, early puberty, endometriosis, and diseases and cancers of reproductive organs. The compelling nature of the collective science has resulted in recognition of a new field of environmental reproductive health. Focusing on exposures to environmental contaminants, particularly during critical periods in development and their potential effects on all aspects of future reproductive life-course, this book provides the first comprehensive source of information bringing together the arguments that are spread out among various scientific disciplines in environmental health, clinical and public health fields. It provides a review of the science in key areas of the relationship between environmental contaminants and reproductive health outcomes, and recommendations on efforts toward prevention in clinical care and public policy.

Hormonally Active Agents in the Environment

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309064198
Total Pages : 453 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Hormonally Active Agents in the Environment by : National Research Council

Download or read book Hormonally Active Agents in the Environment written by National Research Council and published by National Academies Press. This book was released on 2000-02-03 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.

Bisphenol A

Author : Pinar Erkekoglu
Publisher : BoD – Books on Demand
ISBN 13 : 9535132172
Total Pages : 166 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Bisphenol A by : Pinar Erkekoglu

Download or read book Bisphenol A written by Pinar Erkekoglu and published by BoD – Books on Demand. This book was released on 2017-06-07 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bisphenol A (BPA) is a synthetic compound for hardening and clearing polycarbonate plastics. BPA is mainly classified as an estrogen-like endocrine-disrupting chemical. In the last decade, attention has arisen in scientific communities that it is not safe to use this chemical in mainly polycarbonate plastics. Exposure to BPA starts in prenatal period, which is the critical period for its toxic effects on different organs. Throughout this book, the readers will obtain information on the effects of BPA on different systems. They will also get information on the prenatal and postnatal effects of BPA. We believe that readers will get qualified scientific knowledge and a general overview of the toxic effects of BPA exposure and its consequences from this book.

The Leydig Cell in Health and Disease

Author : Anita H. Payne
Publisher : Springer Science & Business Media
ISBN 13 : 1597454532
Total Pages : 471 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis The Leydig Cell in Health and Disease by : Anita H. Payne

Download or read book The Leydig Cell in Health and Disease written by Anita H. Payne and published by Springer Science & Business Media. This book was released on 2007-10-28 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive study of the Leydig cell, a fascinating and important cell type. It presents all of the developments in our understanding of Leydig cell biology and explores a wide variety of current and potential clinical applications. All aspects of Leydig cell biology, development, regulation, and physiology are explored in thirty-one expertly written chapters. This in-depth volume is an invaluable resource.

Environmental Health Risk

Author : Marcelo Larramendy
Publisher : BoD – Books on Demand
ISBN 13 : 9535124013
Total Pages : 280 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Environmental Health Risk by : Marcelo Larramendy

Download or read book Environmental Health Risk written by Marcelo Larramendy and published by BoD – Books on Demand. This book was released on 2016-06-16 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, Environmental Health Risk - Hazardous Factors to Living Species, is intended to provide a set of practical discussions and relevant tools for making risky decisions that require actions to reduce environmental health risk against environmental factors that may adversely impact human health or ecological balances. We aimed to compile information from diverse sources into a single volume to give some real examples extending concepts of those hazardous factors to living species that may stimulate new research ideas and trends in the relevant fields.

Testosterone

Author : Alexandre Hohl
Publisher : Springer Nature
ISBN 13 : 3031315014
Total Pages : 515 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Testosterone by : Alexandre Hohl

Download or read book Testosterone written by Alexandre Hohl and published by Springer Nature. This book was released on 2023 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even though research on testosterone is increasing, there is still much controversy regarding its physiology and clinical use. This book provides a broad overview on testosterone, from its basic features to the most recent evidence of clinical applicability. In addition, specific conditions in which testosterone play a pivotal role are discussed in detail, such as hypogonadism, misuse and abuse, puberty, cardiovascular effects and testosterone therapy. The testes are vital organs for reproduction of the human species, besides being the main source of testosterone production in men. Although not essential for survival, these singular structures represent the essence of male biological function. Testosterone is the most important testicular androgen in men. Low serum testosterone levels are associated with cardiovascular morbidity, metabolic syndrome, type 2 diabetes mellitus, atherosclerosis, osteoporosis, sarcopenia, and mortality. Also, there is increasing evidence that serum testosterone is a major biomarker status of men's health in general. Hypogonadism in a male refers to a decrease in one or both of the two major functions of the testes: sperm production or testosterone production. These abnormalities can result from disease of the testes (primary hypogonadism) or disease of the pituitary or hypothalamus (secondary hypogonadism). Currently, the clinical features of male hypogonadism are sufficiently well-recognized, the causes are well-known, and the tests of the hypothalamic-pituitary-testicular axis are accurate enough for the diagnosis in most patients. Testosterone, the focus hormone of this book, is used in different forms and routes of administration. Several authors unravel its peculiarities and assist in choosing the most suitable form in each case, as well as the possible risks of its misuse or even abuse in men and women, seeking alternatives to help patients in this situation.

Phytoestrogens and Health

Author : G. Sarwar Gilani
Publisher : The American Oil Chemists Society
ISBN 13 : 9781893997325
Total Pages : 682 pages
Book Rating : 4.9/5 (973 download)

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Book Synopsis Phytoestrogens and Health by : G. Sarwar Gilani

Download or read book Phytoestrogens and Health written by G. Sarwar Gilani and published by The American Oil Chemists Society. This book was released on 2002-06-30 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Environment and Breast Cancer

Author : Jose Russo
Publisher : Springer
ISBN 13 : 9781489993915
Total Pages : 0 pages
Book Rating : 4.9/5 (939 download)

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Book Synopsis Environment and Breast Cancer by : Jose Russo

Download or read book Environment and Breast Cancer written by Jose Russo and published by Springer. This book was released on 2014-10-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer is a complex disease caused by multiple environmental and lifestyle factors interacting with genetic susceptibility across the life span. Therefore, environmental factors are of intense interest to both researchers and community members, including women with breast cancer. There is not adequate literature that addresses this issue comprehensively from epidemiological, experimental, and translational research perspective. This book is aiming to fill this gap by gathering chapters from the most recognized experts in the field of breast biology and cancer with special interests in environmental issues.

Phytoremediation

Author : Steven C. McCutcheon
Publisher : John Wiley & Sons
ISBN 13 : 0471459321
Total Pages : 1019 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Phytoremediation by : Steven C. McCutcheon

Download or read book Phytoremediation written by Steven C. McCutcheon and published by John Wiley & Sons. This book was released on 2004-04-05 with total page 1019 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytormediation is an exciting new method for controlling and cleaning up hazardous wastes using green plants. This book is the first to compile the state of the science and engineering arts in this rapidly advancing field. Phytormediation: Approaches the subject from the perspectives of biochemistry, genetics, toxicology, and pathway analysis. Is written by two of the premier experts in the field.

Environment and Female Reproductive Health

Author : Huidong Zhang
Publisher : Springer Nature
ISBN 13 : 9813341874
Total Pages : 315 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Environment and Female Reproductive Health by : Huidong Zhang

Download or read book Environment and Female Reproductive Health written by Huidong Zhang and published by Springer Nature. This book was released on 2021-02-01 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will focus on the harmful effect of environmental toxins on female reproductive health. Reproduction is the basis of the continuation of human beings, and environment is the basis of human survival. However, environmental pollution has become a potential risk factor for human reproductive health, which not only leads to many chronic diseases, but also causes certain harm to reproductive health. Compared to male reproduction, female reproductive process is more complex, the reproductive system is more fragile, and is more vulnerable to be damaged. The aim of this book is to review the research progress, to address the challenges, and to stimulate the development in the direction of environment and female reproductive health.

Developmental Effects of Diethylstilbestrol (DES) in Pregnancy

Author : Arthur L. Herbst
Publisher :
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Developmental Effects of Diethylstilbestrol (DES) in Pregnancy by : Arthur L. Herbst

Download or read book Developmental Effects of Diethylstilbestrol (DES) in Pregnancy written by Arthur L. Herbst and published by . This book was released on 1981 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Encyclopedia of Aquatic Ecotoxicology

Author : Jean-Francois Férard
Publisher : Springer
ISBN 13 : 9789400750401
Total Pages : 0 pages
Book Rating : 4.7/5 (54 download)

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Book Synopsis Encyclopedia of Aquatic Ecotoxicology by : Jean-Francois Férard

Download or read book Encyclopedia of Aquatic Ecotoxicology written by Jean-Francois Férard and published by Springer. This book was released on 2013-06-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: With its 104 chapters, this Encyclopedia of aquatic ecotoxicology reveals the diversity of issues, problems and challenges that have faced, and are facing today, receiving environments. It also indicates ways by which tools, strategies and future investigations can contribute to correct, minimize, solve and prevent water quality degradation. Structured homogeneously, the chapters convey salient information on historical background, features, characteristics, uses and/or applications of treated topics, often complemented by illustrations and case studies, as well as by conclusions and prospects. This work is most suitable for teaching purposes. Academics, for example, could literally deliver comprehensive lectures to students simply based on chapter outlines and contents. Meet the Authors of the Encyclopedia! Check out 'Meet the Authors' under ADDITIONAL INFORMATION (Right menu).

Female Reproductive Dysfunction

Author : Felice Petraglia
Publisher : Springer
ISBN 13 : 9783030147815
Total Pages : 0 pages
Book Rating : 4.1/5 (478 download)

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Book Synopsis Female Reproductive Dysfunction by : Felice Petraglia

Download or read book Female Reproductive Dysfunction written by Felice Petraglia and published by Springer. This book was released on 2020-05-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by leading international specialists, this book provides a comprehensive, state-of-the-art overview of endocrine-based female reproductive disorders. Particularly focusing on the Hypothalamus – Pituitary – Ovary (HPO) axis as the main driver of reproduction in women, it discusses amenorrhea; chronic anovulation and polycystic ovary syndrome as the most common dysfunctions of the HPO axis; endocrine diseases as possible impacts on the HPO axis; uterine disorders related to estrogen/progesterone; and the impact of endometriosis and uterine fibroids on reproduction. It also addresses infertility and menopause as hormone-related disorders in women and endocrine changes during pregnancy and lactation, and in breast disorders. The book is intended as a major reference for endocrinologists, gynecologists, and obstetricians, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which provides access to live editions constantly updated through a dynamic peer-review publishing process.