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Virus Discovery By Metagenomics The Impossibilities
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Book Synopsis Virus Discovery by Metagenomics: The (Im)possibilities by : Bas E. Dutilh
Download or read book Virus Discovery by Metagenomics: The (Im)possibilities written by Bas E. Dutilh and published by Frontiers Media SA. This book was released on 2017-10-25 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the late 1800s, the discovery of new viruses was a gradual process. Viruses were described one by one using a suite of techniques such as (electron) microscopy and viral culture. Investigators were usually interested in a disease state within an organism, and expeditions in viral ecology were rare. The advent of metagenomics using high-throughput sequencing has revolutionized not only the rate of virus discovery, but also the nature of the discoveries. For example, the viral ecology and etiology of many human diseases are being characterized, non-pathogenic viral commensals are ubiquitous, and the description of environmental viromes is making progress. This Frontiers in Virology Research Topic showcases how metagenomic and bioinformatic approaches have been combined to discover, classify and characterize novel viruses.
Book Synopsis Desk Encyclopedia of Microbiology by : Moselio Schaechter
Download or read book Desk Encyclopedia of Microbiology written by Moselio Schaechter and published by Academic Press. This book was released on 2010-04-19 with total page 1277 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Desk Encyclopedia of Microbiology, Second Edition is a single-volume comprehensive guide to microbiology for the advanced reader. Derived from the six volume e-only Encyclopedia of Microbiology, Third Edition, it bridges the gap between introductory texts and specialized reviews. Covering topics ranging from the basic science of microbiology to the current "hot" topics in the field, it will be invaluable for obtaining background information on a broad range of microbiological topics, preparing lectures and preparing grant applications and reports. - The most comprehensive single-volume source providing an overview of microbiology to non-specialists - Bridges the gap between introductory texts and specialized reviews - Provides concise and general overviews of important topics within the field making it a helpful resource when preparing for lectures, writing reports, or drafting grant applications
Book Synopsis Ticks and Tick-Borne Pathogens by : Muhammad Abubakar
Download or read book Ticks and Tick-Borne Pathogens written by Muhammad Abubakar and published by BoD – Books on Demand. This book was released on 2019-03-13 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is vital to understand ticks and tick-borne pathogens as well as their impact on humans. This book is intended for students in parasitology, biologists, parasitologists involved in molecular diagnostics of tick-borne diseases, practicing veterinarians, and for others who may require information on ticks and tick-borne diseases. Here we have put together a collection of chapters focused on different aspects of ticks and tick-borne diseases mainly to provide the reader with novel information in the field, but not the basic generalised information provided by many textbooks. This book includes topics such as high-throughput technologies in diagnosis, discovery of novel tick vaccines, identification of new pathogens transmitted by ticks, and new epidemiological information of certain well-known ticks and tick-borne diseases. These chapters were authored by parasitologists from all over the world, giving an insight to the reader about significant ticks and tick-borne diseases prevalent in those particular geographical regions with the local expert's point of view. Each of the chapters has separate reference lists, making it easier for the reader to find additional reading material related to their topic of interest.
Book Synopsis Genomic Medicine by : Dhavendra Kumar
Download or read book Genomic Medicine written by Dhavendra Kumar and published by Oxford Monographs on Medical G. This book was released on 2014-10-15 with total page 853 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preceded by Genomics and clinical medicine / edited by Dhavendra Kumar. [First edition]. 2008.
Book Synopsis Viruses: Essential Agents of Life by : Günther Witzany
Download or read book Viruses: Essential Agents of Life written by Günther Witzany and published by Springer Science & Business Media. This book was released on 2012-11-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: A renaissance of virus research is taking centre stage in biology. Empirical data from the last decade indicate the important roles of viruses, both in the evolution of all life and as symbionts of host organisms. There is increasing evidence that all cellular life is colonized by exogenous and/or endogenous viruses in a non-lytic but persistent lifestyle. Viruses and viral parts form the most numerous genetic matter on this planet.
Book Synopsis Metagenomics for Microbiology by : Jacques Izard
Download or read book Metagenomics for Microbiology written by Jacques Izard and published by Academic Press. This book was released on 2014-11-07 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concisely discussing the application of high throughput analysis to move forward our understanding of microbial principles, Metagenomics for Microbiology provides a solid base for the design and analysis of omics studies for the characterization of microbial consortia. The intended audience includes clinical and environmental microbiologists, molecular biologists, infectious disease experts, statisticians, biostatisticians, and public health scientists. This book focuses on the technological underpinnings of metagenomic approaches and their conceptual and practical applications. With the next-generation genomic sequencing revolution increasingly permitting researchers to decipher the coding information of the microbes living with us, we now have a unique capacity to compare multiple sites within individuals and at higher resolution and greater throughput than hitherto possible. The recent articulation of this paradigm points to unique possibilities for investigation of our dynamic relationship with these cellular communities, and excitingly the probing of their therapeutic potential in disease prevention or treatment of the future. - Expertly describes the latest metagenomic methodologies and best-practices, from sample collection to data analysis for taxonomic, whole shotgun metagenomic, and metatranscriptomic studies - Includes clear-headed pointers and quick starts to direct research efforts and increase study efficacy, eschewing ponderous prose - Presented topics include sample collection and preparation, data generation and quality control, third generation sequencing, advances in computational analyses of shotgun metagenomic sequence data, taxonomic profiling of shotgun data, hypothesis testing, and mathematical and computational analysis of longitudinal data and time series. Past-examples and prospects are provided to contextualize the applications.
Book Synopsis Contracting for ABS by : Shakeel Bhatti
Download or read book Contracting for ABS written by Shakeel Bhatti and published by IUCN. This book was released on 2009 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contracts relating to scientific/technical development are effective only where they are enforceable or valid under relevant law, can be practically implemented by the parties, and address matters arising from the relevant scientific/technical issues and practices. Negotiators are often hampered by their lack of knowledge of contract law and of the biotechnological techniques used to derive new molecules and genes or genetic or biochemical formulas from biological samples. This lack of knowledge means they may not make the best choices. This book examines the special issues in applying contract law to the rights to take and utilize genetic resources; and the scientific issues and the manner in which they affect the negotiation of ABS agreements.
Book Synopsis Microorganisms in Sustainable Agriculture and Biotechnology by : T. Satyanarayana
Download or read book Microorganisms in Sustainable Agriculture and Biotechnology written by T. Satyanarayana and published by Springer Science & Business Media. This book was released on 2012-01-02 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: This review of recent developments in our understanding of the role of microbes in sustainable agriculture and biotechnology covers a research area with enormous untapped potential. Chemical fertilizers, pesticides, herbicides and other agricultural inputs derived from fossil fuels have increased agricultural production, yet growing awareness and concern over their adverse effects on soil productivity and environmental quality cannot be ignored. The high cost of these products, the difficulties of meeting demand for them, and their harmful environmental legacy have encouraged scientists to develop alternative strategies to raise productivity, with microbes playing a central role in these efforts. One application is the use of soil microbes as bioinoculants for supplying nutrients and/or stimulating plant growth. Some rhizospheric microbes are known to synthesize plant growth-promoters, siderophores and antibiotics, as well as aiding phosphorous uptake. The last 40 years have seen rapid strides made in our appreciation of the diversity of environmental microbes and their possible benefits to sustainable agriculture and production. The advent of powerful new methodologies in microbial genetics, molecular biology and biotechnology has only quickened the pace of developments. The vital part played by microbes in sustaining our planet’s ecosystems only adds urgency to this enquiry. Culture-dependent microbes already contribute much to human life, yet the latent potential of vast numbers of uncultured—and thus untouched—microbes, is enormous. Culture-independent metagenomic approaches employed in a variety of natural habitats have alerted us to the sheer diversity of these microbes, and resulted in the characterization of novel genes and gene products. Several new antibiotics and biocatalysts have been discovered among environmental genomes and some products have already been commercialized. Meanwhile, dozens of industrial products currently formulated in large quantities from petrochemicals, such as ethanol, butanol, organic acids, and amino acids, are equally obtainable through microbial fermentation. Edited by a trio of recognized authorities on the subject, this survey of a fast-moving field—with so many benefits within reach—will be required reading for all those investigating ways to harness the power of microorganisms in making both agriculture and biotechnology more sustainable.
Book Synopsis Frontiers of Life by : J. Thanh Van Tran
Download or read book Frontiers of Life written by J. Thanh Van Tran and published by Atlantica Séguier Frontières. This book was released on 1992 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis An Introduction to Ecological Genomics by : Nico M. van Straalen
Download or read book An Introduction to Ecological Genomics written by Nico M. van Straalen and published by Oxford University Press. This book was released on 2012 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors also provide a comparative survey of the properties of genomes (genome size, gene families, synteny, and polymorphism) for prokaryotes as well as the main eukaryotic models.
Book Synopsis Cytokines in Inflammatory Bowel Disease by : Claudio Fiocchi
Download or read book Cytokines in Inflammatory Bowel Disease written by Claudio Fiocchi and published by . This book was released on 1996 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pathogenesis of both forms of inflammatory bowel disease, Crohn's disease and ulcerative colitis, depends on complex immune abnormalities, and the investigation of cytokines has become critical to basic, clinical and therapeutic aspects of these enigmatic entities. This book offers clear, concise, state-of-the-art information on the role of various immunoregulatory and pro-inflammatory mediators in Crohn's disease and ulcerative colitis. Each cytokine is analyzed in regard to pathogenic and clinical implications, taking advantage of information derived from patients, animal models, as well as immunological and molecular in vitro systems. This volume is of interest to gastroenterologists, clinical investigators, immunologists, cell biologists and any professional interested in mucosal immunity and inflammation.
Download or read book Gnotobiotics written by Trenton R Schoeb and published by Academic Press. This book was released on 2017-08-11 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gnotobiotics summarizes and analyzes the research conducted on the use of gnotobiotes, providing detailed information regarding actual facility operation and derivation of gnotobiotic animals. In response to the development of new tools for microbiota and microbiome analysis, the increasing recognition of the various roles of microbiota in health and disease, and the consequent expanding demand for gnotobiotic animals for microbiota/microbiome related research, this volume collates the research of this expanding field into one definitive resource. - Reviews and defines gnotobiotic animal species - Analyzes microbiota in numerous contexts - Presents detailed coverage of the protocols and operation of a gnotobiotic facility
Book Synopsis Microbial Versatility in Varied Environments by : Raghvendra Pratap Singh
Download or read book Microbial Versatility in Varied Environments written by Raghvendra Pratap Singh and published by Springer Nature. This book was released on 2020-04-09 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book compiles the latest studies on microorganisms thriving in extreme conditions. Microbes have been found in extremely high and low temperatures, highly acidic to saline conditions, from deserts to the Dead sea, from hot-springs to underwater hydrothermal vents- the diversity is incredible. The various chapters highlight the microbial life and describe the mechanisms of tolerance to these harsh conditions, and show how an understanding of these phenomena can help us exploit the microbes in biotechnology. The theme of the book is highly significant since life in these environments can give vital clues about the origin and evolution of life on earth, as a lot of these conditions simulate the environment present billions of years ago. Additionally, the study of adaptation and survival of organisms in such environments can be important for finding life on other planets. This book shall be useful for students, researchers and course instructors interested in evolution, microbial adaptations and ecology in varied environments.
Book Synopsis Discovering Life, Manufacturing Life by : Pierre V. Vignais
Download or read book Discovering Life, Manufacturing Life written by Pierre V. Vignais and published by Springer Science & Business Media. This book was released on 2010-06-21 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Francis BACON, in his Novum Organum, Robert BOYLE, in his Skeptical Chemist and René DESCARTES, in his Discourse on Method; all of these men were witnesses to the th scientific revolution, which, in the 17 century, began to awaken the western world from a long sleep. In each of these works, the author emphasizes the role of the experimental method in exploring the laws of Nature, that is to say, the way in which an experiment is designed, implemented according to tried and tested te- niques, and used as a basis for drawing conclusions that are based only on results, with their margins of error, taking into account contemporary traditions and prejudices. Two centuries later, Claude BERNARD, in his Introduction to the Study of Experimental Medicine, made a passionate plea for the application of the experimental method when studying the functions of living beings. Twenty-first century Biology, which has been fertilized by highly sophisticated techniques inherited from Physics and Chemistry, blessed with a constantly increasing expertise in the manipulation of the genome, initiated into the mysteries of information techn- ogy, and enriched with the ever-growing fund of basic knowledge, at times appears to have forgotten its roots.
Book Synopsis Diversity and Benefits of Microorganisms from the Tropics by : João Lucio de Azevedo
Download or read book Diversity and Benefits of Microorganisms from the Tropics written by João Lucio de Azevedo and published by Springer. This book was released on 2017-06-10 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the diversity of tropical microorganisms and its applications in agriculture, renewable energy production and environmental protection. It covers several tropical habitats such as rain forests, mangroves, sea and river waters and describes how microorganisms isolated from these regions can be used to control insects and plant diseases, to improve sugar cane and biofuels production among other applications. The book also aims to bring researchers’ attention to the potential of tropical microorganisms for biotechnological purposes, an area that is still far from being well explored.
Book Synopsis COVID-19 Pandemic – Philosophical Approaches by : Nicolae Sfetcu
Download or read book COVID-19 Pandemic – Philosophical Approaches written by Nicolae Sfetcu and published by Nicolae Sfetcu. This book was released on with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: The paper begins with a retrospective of the debates on the origin of life: the virus or the cell? The virus needs a cell for replication, instead the cell is a more evolved form on the evolutionary scale of life. In addition, the study of viruses raises pressing conceptual and philosophical questions about their nature, their classification, and their place in the biological world. The subject of pandemics is approached starting from the existentialism of Albert Camus and Sartre, the replacement of the exclusion ritual with the disciplinary mechanism of Michel Foucault, and about the Gaia hypothesis, developed by James Lovelock and supported in the current pandemic by Bruno Latour. The social dimensions of pandemics, their connection to global warming, which has led to an increase in infectious diseases, and the deforestation of large areas, which have caused viruses to migrate from their native area (their "reservoir") are highlighted below. The ethics of pandemics is approached from several philosophical points of view, of which the most important in a crisis of such global dimensions is utilitarianism which involves maximizing benefits for society in direct conflict with the usual (Kantian) view of respect for people as individuals. After a retrospective of the COVID-19 virus that caused the current pandemic, its life cycle and its history, with an emphasis on the philosophy of death, the concept of biopower initially developed by Foucault is discussed, with reference to the practice of modern states of control of the populations and the debate generated by Giorgio Agamben who states that what is manifested in this pandemic is the growing tendency to use the state of emergency as a normal paradigm of government. An interesting and much debated approach is the one generated by the works of Slavoj Žižek, who states that the current pandemic has led to the bankruptcy of the current "barbaric" capitalism, wondering if the path that humanity will take is a neo-communism. Another important negative effect is desocialization, with the conclusion of some philosophers that we cannot exist independently of our relationships with others, that a person's humanity depends on the humanity of those around him. The last section is dedicated to forecasting what the world will look like after the pandemic, and there are already signs of a paradigm shift, including the sudden disappearance of the "wall" ideology: a cough was enough to make it suddenly impossible to avoid the responsibility that every individual has it towards all living beings for the simple fact that he is part of this world, and of the desire to be part of it. The whole is always involved in part, because everything is, in a sense, in everything and in nature there are no autonomous regions that are an exception. The COVID-19 pandemic seems to restore the supremacy that once belonged to politics. One of the virtues of the virus is its ability to generate a more sober idea of freedom: to be free means to do what needs to be done in a specific situation. CONTENTS: Abstract Introduction 1 Viruses 1.1 Ontology 2 Pandemics 2.1 Social dimensions 2.2 Ethics 3 COVID-19 3.1 Biopolitics 3.2 Neocommunism 3.3 Desocialising 4 Forecasting Bibliography DOI: 10.13140/RG.2.2.31039.74405/1
Book Synopsis Big Farms Make Big Flu by : Rob Wallace
Download or read book Big Farms Make Big Flu written by Rob Wallace and published by NYU Press. This book was released on 2016-06-30 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first collection to explore infectious disease, agriculture, economics, and the nature of science together Thanks to breakthroughs in production and food science, agribusiness has been able to devise new ways to grow more food and get it more places more quickly. There is no shortage of news items on hundreds of thousands of hybrid poultry—each animal genetically identical to the next—packed together in megabarns, grown out in a matter of months, then slaughtered, processed and shipped to the other side of the globe. Less well known are the deadly pathogens mutating in, and emerging out of, these specialized agro-environments. In fact, many of the most dangerous new diseases in humans can be traced back to such food systems, among them Campylobacter, Nipah virus, Q fever, hepatitis E, and a variety of novel influenza variants. Agribusiness has known for decades that packing thousands of birds or livestock together results in a monoculture that selects for such disease. But market economics doesn't punish the companies for growing Big Flu—it punishes animals, the environment, consumers, and contract farmers. Alongside growing profits, diseases are permitted to emerge, evolve, and spread with little check. “That is,” writes evolutionary biologist Rob Wallace, “it pays to produce a pathogen that could kill a billion people.” In Big Farms Make Big Flu, a collection of dispatches by turns harrowing and thought-provoking, Wallace tracks the ways influenza and other pathogens emerge from an agriculture controlled by multinational corporations. Wallace details, with a precise and radical wit, the latest in the science of agricultural epidemiology, while at the same time juxtaposing ghastly phenomena such as attempts at producing featherless chickens, microbial time travel, and neoliberal Ebola. Wallace also offers sensible alternatives to lethal agribusiness. Some, such as farming cooperatives, integrated pathogen management, and mixed crop-livestock systems, are already in practice off the agribusiness grid. While many books cover facets of food or outbreaks, Wallace's collection appears the first to explore infectious disease, agriculture, economics and the nature of science together. Big Farms Make Big Flu integrates the political economies of disease and science to derive a new understanding of the evolution of infections. Highly capitalized agriculture may be farming pathogens as much as chickens or corn.
